Clinical trials: Movement Disorder
Huntington's Disease
Cognitive Assessment Battery (CAB) Beta Study
The overall objective of this study is to identify a 60 minute cognitive battery, for subsequent use in clinical trials, that detects cognitive deficits in early HD and late pre-manifest HD compared to controls, and that has a…
- Trial name
- CAB (NCT01290861)
- Where
- 20 sites in United States, Australia and 2 more
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- CHDI Foundation, Inc.
Parkinson's Disease
Facial Expression Recognition and Mirror Neurons in Parkinson's Disease
After few years of evolution, patients with Parkinson's disease may develop apathy, with different degrees of severity. Apathy is characterized by a loss of interest for the others and for activities.
- Trial name
- NCT01315405
- Testing
- Emotional facial expression recognition tests
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Ataxia, Cerebrovascular Accident
PET Scan to Study Brain Control of Human Movement
Positron Emission Tomography (PET) is a technique used to investigate activity in areas of the brain. The PET technique allows researchers to study the normal processes in the brain (central nervous system) of normal individuals…
- Conditions
- Ataxia, Cerebrovascular Accident, Healthy, Movement Disorder
- Trial name
- NCT00001324
- Where
- United States
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
ALS, Amyotrophic Lateral Sclerosis
Cortex Changes in Real/Imagined Movements in Amyotrophic Lateral Sclerosis (ALS)
The purpose of this study is to track areas of the brain, via functional magnetic resonance imaging (fMRI), that retain structural and functional integrity throughout the lifespan of people with amyotrophic lateral sclerosis…
- Trial name
- NCT00809224
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Physical Inactivity, Obesity, Childhood
Gamified Family-based Health Exercise Intervention to Improve Adherence to 24-h Movement Behaviors Recommendations in Children.
Physical inactivity is the fourth most important risk factor for mortality worldwide and it contributes to weight gain and obesity.
- Conditions
- Physical Inactivity, Obesity, Childhood, Sedentary Behavior
- Trial name
- Move On (NCT05741879)
- Testing
- Gamified exercise training, Standard Care
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Pública de Navarra
Hand Injuries and Disorders
System for Quantifying the Functional Strength of the Grip and Pinch Movements
This study developed a system to quantify the functional strength of young adults without motor impairment during grip and pinch movement.
- Trial name
- NCT04174729
- Testing
- handgrip strength, Door handle device, Tap device
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Mogi das Cruzes
Clinical Reasoning, Cerebral Palsy
Tracking General Movements
Background: General movements (GMs) are endogenously generated movements of the entire body observable from the 9th week postmenstrual age to at least 20 weeks postterm age.
- Conditions
- Clinical Reasoning, Cerebral Palsy, General Movement Assessment
- Trial name
- NCT04241445
- Where
- Austria
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Parkinson Disease
Perception, Cognition, and Gait in Parkinson's Disease
The investigators are examining how aspects of daily function are perceived in persons with PD and in those who interact with them on a regular basis.
- Trial name
- NCT03241966
- Where
- United States
- Volunteers
- 439 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Cervical Spondylosis, Mulligan Mobilization
Muscle Energy Versus Mulligan Techniques in Treating Patients With Cervical Spondylosis
This study will be aimed to answer the following questions: Which technique, MET or MMT, is more effective in reducing pain, increasing range of motion (ROM), improving proprioception, and enhancing functional ability in…
- Conditions
- Cervical Spondylosis, Mulligan Mobilization, SNAGs, Muscle Energy Technique
- Trial name
- NCT06664931
- Testing
- Group (A) Muscle Energy Technique (MET), Group (B) Mulligan Mobilizations Techniques (MMT).
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Amyotrophic Lateral Sclerosis, Neurodegenerative Disease
Amyotrophic Lateral Sclerosis (ALS) Tissue Donation Program
Despite significant progress in the identification of mechanisms involved in motor neuron degeneration in Amyotrophic Lateral Sclerosis (ALS) and other motor system diseases, the actual pathogenesis and cause of these diseases…
- Conditions
- Amyotrophic Lateral Sclerosis, Neurodegenerative Disease, Motor Neuron Disease
- Trial name
- NCT00716131
- Where
- United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Drexel University College of Medicine
Parkinson Disease
Merging Yoga and Occupational Therapy for Parkinson Disease: Phase 2
The full program is focused on identifying and reducing risk factors surrounding falls. Based on previous research, we believe that occupational therapy group classes and adaptive yoga are an ideal pairing to reduce fall risk.
- Trial name
- MY-OT for PD (NCT03578653)
- Testing
- Merging Yoga and Occupational Therapy for Parkinson disease
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Idiopathic Parkinson Disease
A Prospective Study to Evaluate the Correlation Between Oculometric Measurements and Clinical Endpoints in PD Patients
This is a prospective study in a cohort of about 500 patients with Idiopathic Parkinson's disease, examined routinely in the neurological outpatient clinic.
- Trial name
- NCT05437003
- Testing
- NeuraLight software-based platform
- Where
- Israel
- Volunteers
- 465 people, healthy volunteers welcome
- Sponsor
- NeuraLight
Decreased Fetal Movements Affecting Care of Mother, Pregnancy
Promoting Awareness Fetal Movements to Reduce Fetal Mortality Stillbirth, a Stepped Wedge Cluster Randomised Trial.
Rates of stillbirth in Scotland are among the highest in resource rich countries. The majority of stillbirths occur in normally formed infants, with (retrospective) evidence of placental insufficiency being the commonest clinical…
- Conditions
- Decreased Fetal Movements Affecting Care of Mother, Pregnancy, Stillbirth
- Trial name
- AFFIRM (NCT01777022)
- Testing
- A package of interventions
- Where
- 29 sites in Ireland, United Kingdom
- Volunteers
- 430,830 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Caregiver Stress, Dementia
A Study of Caregiver Connections Via Technology in Dementia
This research is being done to develop a unique matching process for caregivers of persons living with dementia, such as Alzheimer's disease, Lewy body dementia, frontotemporal degeneration, or other dementia syndromes.
- Conditions
- Caregiver Stress, Dementia, Alzheimer Disease, Lewy Body Dementia
- Trial name
- NCT05779839
- Testing
- Algorithm, Random Match
- Where
- United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Parkinson Disease, Accidental Fall
Development and Evaluation of a Guide to Help People With Parkinson's and Their Caregivers to Self-manage Falling
This study will investigate whether it is possible, through the development and evaluation of a self-management guide, to improve health related quality of life and concern of falling in people with Parkinson's disease who fall…
- Trial name
- NCT03111472
- Testing
- Self-management guide for people with Parkinson's who fall and their informal caregivers
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Wilson's Disease, Myocardial Dysfunction
Subclinical Myocardial Dysfunction in Children With Wilson's Disease
Wilson's disease (WD) is one of the most common metabolic liver diseases in older children. The most frequent clinical presentation is liver disease. However, Wilson's disease (WD) is a multisystem disorder.
- Conditions
- Wilson's Disease, Myocardial Dysfunction, Children, Wilson Disease
- Trial name
- NCT07765472
- Testing
- Echocardiography, Electrocardiography, N-terminal pro b- type natriuretic peptide
- Where
- 2 sites in Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hebatullah Fawzy
Movement Disorders, Aging
Effects of Exercise Poles on Older Adults During Exercise Walking
This study uses a patented type of exercise poles, developed to assist runners rehabilitating from lower body injuries. These poles may offer older adults improved stability, reduced fear of falling, and lessened lower body pain…
- Trial name
- NCT00037167
- Testing
- Exercise poles
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Tourette's Syndrome, Chronic Motor Tic Disorder
Brain Activation in Vocal and Motor Tics
This study will investigate the brain areas that are activated by vocal and motor tics in patients with Tourette's syndrome and other tic disorders. Tics are involuntary repetitive movements similar to voluntary movements.
- Conditions
- Tourette's Syndrome, Chronic Motor Tic Disorder, Chronic Motor Vocal Disorder
- Trial name
- NCT00026000
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Parkinson Disease
ALTROPANE® SPECT Imaging in Patients With Parkinson Disease
After a screening evaluation including baseline clinical laboratory testing, a physical and neurological evaluation, subjects will be asked to undergo an injection of ALTROPANE® followed by up to 60 minutes of serial dynamic…
- Trial name
- NCT00397228
- Testing
- ALTROPANE®
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Molecular NeuroImaging
Huntington Disease
Study of Biomarkers That Predict the Evolution of Huntington's Disease
Huntington's disease (HD) is a rare, autosomal dominant, progressive neurodegenerative disorder typically becoming noticeable in middle age.
- Trial name
- BIOHD (NCT01412125)
- Testing
- Huntington patient evaluation, Healthy subject evaluation
- Where
- France
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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