Clinical trials: Movement Disorder
Pulmonary Disease, Autonomic Dysfunction
Meditative Movement for COPD Symptoms in Non-Smoking Flight Attendants
This study will explore the a Qigong based exercise intervention, here referred to as Meditative Movement (MM), to ameliorate the symptoms associated with chronic obstructive pulmonary disease (COPD) and its co-morbidities.
- Conditions
- Pulmonary Disease, Autonomic Dysfunction, COPD
- Trial name
- MMforFA (NCT02612389)
- Testing
- Meditative Movement taught via DVD
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Stroke, Movement, Abnormal
Effect of Virtual Reality Game on Upper Limb Movement in Individuals With Stroke
Individuals with stroke show abnormal movement pattern of upper limb. The movement pattern needs to be corrected. There are several methods to train normal movement.
- Trial name
- VRULS (NCT03277950)
- Testing
- Virtual reality with feedback, Virtual reality without feedback, Healthy
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Vimonwan Hiengkaew
PARKINSON DISEASE (Disorder)
Open Label Single Arm Prebiotic Pilot Trial SR001
The goal of this pilot clinical study is to evaluate the effect of a prebiotic fiber blend in individuals diagnosed with Parkinson's Disease. The main objectives of this pilot study are: 1.
- Trial name
- NCT07127120
- Testing
- Prebiotic fiber blend
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sorridi Therapeutics
Cerebral Palsy, Prematurity
Study of Generalized Movements for Early Prediction of Cerebral Palsy
The purpose of this study is to assess the predictive value of generalized movements in preterm and term infants who are at risk for development of cerebral palsy.
- Trial name
- NCT00749008
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Charles R. Neal,
Parkinson Disease
Study of Dysarthria, and the Appearance of Non-dopaminergic Signs in Idiopathic PARKinson's Disease
Pilot study: Longitudinal follow up of the PRODY-GI cohort for parkinson's disease (PD) Observational study of upper and lower axial symptoms' occurence in 30 PD patients in on and off drug conditions, 30 aged matched control…
- Trial name
- Prodygi-II (NCT03517059)
- Where
- France
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Alzheimer's Disease, Healthy Controls
Development of Eye-movement Based Biomarkers in Alzheimer's Disease
This study aims to develop and validate a sensitive and non-invasive eye-tracking software application. This study will obtain participant responses to brief cognitive tests designed to evaluate several key functions known to be…
- Trial name
- NCT05176704
- Testing
- Eye-Tracking
- Where
- 5 sites in Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- McGill University
Parkinson's Disease
Optimization of fMRI for the Study of Basal Ganglia Activation in Parkinson's Disease
Functional magnetic resonance imaging (fMRI) is a non-invasive imaging technique assessing neuronal activations during motor or cognitive tasks.
- Trial name
- 2010-A01115-34 (NCT01429909)
- Testing
- MAGNETOM Avanto (MRI device)
- Where
- France
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Parkinson's Disease
18F-DTBZ for l Diagnosis of Parkinson's Disease and Monitoring the Severity of Disease by VMAT2 PET Imaging
The primary objective of this protocol is to analyze the sensitivity and specificity of 18F-DTBZ PET to the differential diagnosis of Parkinson's Disease (PD) and normality.
- Trial name
- 8F-DTBZ (NCT01283347)
- Testing
- 18F-DTBZ
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Tic Disorders
A Naturalistic Study Investigating Sleep and Cognitive Learning in Children With and Without Tic Disorders
This study will explore the relationship between sleep, learning, cognition, mood and behaviour in children with Tic Disorders (Tourette Syndrome and Chronic Tic Disorder) compared to typically developing peers.
- Trial name
- NCT02676492
- Testing
- Actigraphy to measure sleep duration and efficiency, 'Sleepsuite' novel cognitive learning tasks
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- King's College London
Dementia With Lewy Bodies, Degeneration Nerves
Visualising Cerebral and Peripheral Cholinergic Nerves in Patients With Dementia Lewy Bodies.
Lewy Body Dementia (DLB) is the second most common type of neurodegenerative dementia and characterized by loss of cholinergic neurons in the cerebrum and possibly also internal organs.
- Conditions
- Dementia With Lewy Bodies, Degeneration Nerves, Positron-Emission Tomography, Acetylcholine
- Trial name
- NCT04291144
- Testing
- PET-CT using FEOBV, MRI-scan, Cognitive assessment
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Alzheimer's Disease (AD), Lewy Body Dementia (LBD)
Social-cognitive Functioning: Validation of a New Neuropsychological Test
It is now established that disturbances in social cognition are frequent in neurology and that they contribute to the development of social conduct disorders.
- Conditions
- Alzheimer's Disease (AD), Lewy Body Dementia (LBD), Frontotemporal Degeneration (FTD)
- Trial name
- REALSOCOG (NCT05558709)
- Testing
- REALSOCOG, BCS, Hetero-questionnaires
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Parkinson Disease
Dance Well Therapy: a Study for Evaluating Efficacy, Safety, and Feasibility
A new and in-teresting complementary approach for rehabilitation of parkinsonian patients is represented by "Dance Well", which is an artistic, multisensory dance intervention based on art and music.
- Trial name
- DWpsVMF (NCT06896123)
- Testing
- Dance Well: an artistic, multisensory dance intervention based on art and music, Conventional motor therapy group
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Casa di Cura Villa Margherita Fresco
Limb Loss, Limb Weakness
Analysis of Human Movement With Assistive Devices
The purpose of this research is to evaluate how people move about in different settings with different assistive devices or components, and to understand how people interact with different assistive technologies.
- Conditions
- Limb Loss, Limb Weakness, Limb Paralysis, Movement Disorders
- Trial name
- NCT05729061
- Testing
- Assist-Knee, Prosthetic Knee, Prosthetic Ankle
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Orthocare Innovations, LLC
Parkinson Disease
Effect of BIA 6-512 at Steady-state on the Levodopa Pharmacokinetics
The purpose of the study was to To investigate whether the administration of BIA 6-512 (25 mg, 50 mg, 75 mg and 100 mg) at steady-state affects the pharmacokinetics of levodopa when administered in combination with a single-dose…
- Trial name
- NCT03094156
- Testing
- BIA 6-512, Madopar® 250, Comtan®
- Where
- Portugal
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Bial - Portela C S.A.
Parkinson's Disease
Electromyography Signals as Biomarkers for Parkinson's Disease
A simple, painless and reliable method to detect Parkinson's disease at an early stage is very important to patients, doctors and researchers.
- Trial name
- NCT02168504
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Norconnect Inc
Healthy Volunteers
A First-in-Human Study of Single and Multiple Doses of anle138b in Healthy Subjects
The purpose of this study is to determine the safety, tolerability and blood levels of orally administered anle138b in healthy subjects.
- Trial name
- NCT04208152
- Testing
- anle138b
- Where
- United Kingdom
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- MODAG GmbH
Parkinson's Disease
Subthalamic Deep Brain Stimulation (DBS) in Parkinson's Disease
The purpose of this study is to examine the brain changes in people with Parkinson's Disease (PD) after they get deep brain stimulation (DBS) surgery, compared with people who do not have Parkinson's Disease.
- Trial name
- NCT02012647
- Testing
- Transcranial Magnetic Stimulation (TMS), Motor Physiology Testing
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Florida
Parkinson Disease
Non-invasive Brain Mapping of Movement Facilitation in Parkinson's Disease
Several strategies or contexts help patients with Parkinson's disease to move more quickly or normally, however the brain mechanisms underlying these phenomena are poorly understood.
- Trial name
- NCT05179187
- Testing
- Movement task
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Alzheimer's Disease, Dementia
Blood Gene Expression Signature in Patients Diagnosed With Probable Alzheimer's Disease Compared to Patients Suffering From Other Types of Dementia
The objective of the study is to define the performance of blood-based signatures for Alzheimer's Disease (AD) in different patients populations including AD, non-AD dementia, and non-demented controls.
- Trial name
- NCT00880347
- Testing
- Blood sampling
- Where
- 21 sites in France
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Exonhit
Parkinson Disease
the Effect of Speed Dependent Treadmill Training on Dual Task Performance in Patient With Parkinson's Disease.
The aim of this randomized clinical trail is to identify the impact of treadmill training on walking while doing dual task in patients with Parkinson's disease.
- Trial name
- NCT05903755
- Testing
- speed dependent treadmill training on moderate speed, speed dependent treadmill training on slow speed
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Riphah International University
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