Clinical trials: Movement Disorders, Functional
Healthy Older Adults, Parkinson Disease
Brain Activity, Cognitive Function, and Walking Ability in Parkinson's Disease
The dual-task automated walking performance in people with Parkinson\'s disease (PD) is affected by their gait disturbances and impaired executive functions.
- Trial name
- NCT06588920
- Testing
- Cognitive function, gait, and electroencephalogram
- Where
- 2 sites in Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Parkinson's Disease
The Effect of Rasagiline on Cognition in Parkinson's Disease
While Parkinson's disease has historically been defined in terms of its motor symptomatology, studies have shown that non-motor deficits form an important part of the syndrome.
- Trial name
- NCT01382342
- Testing
- Rasagiline
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Brown University
Kinesiophobia (Fear of Movement), Rhematoid Arthritis
Kinesiophobia in Rheumatoid Arthritis: Associations With Functional Disability, Disease Activity, and Related Clinical Factors
Objectives: Impairment of physical function is a core feature of RA, particularly in patients with high disease activity where pain and inflammation directly limit movement.
- Conditions
- Kinesiophobia (Fear of Movement), Rhematoid Arthritis, Rheumatoid Arthritis (RA), Rheumatoid
- Trial name
- NCT07435272
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Minia University
Parkinson Disease, Balance
Non-motor Symptoms, Balance, Muscle Strength, and Functional Mobility in Patients With Parkinson's Disease
The purposes of this study is to examine balance, muscle strength, and mobility in relation with non-motor symptoms (NMSs) in patients with Parkinsosn's Disease (PD).
- Conditions
- Parkinson Disease, Balance, Muscle Strength, Mobility
- Trial name
- NCT04420910
- Testing
- Non-Motor Symptoms, Balance, Lower Limb Strength
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Parkinson's Disease
Galantamine Executive Function in Parkinson's Disease
The aim of the study is to determine whether galantamine stabilizes or improves thinking abilities in individuals with Parkinson's disease.
- Trial name
- NCT00211588
- Testing
- galantamine
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Memorial Hospital of Rhode Island
Dysphagia, Gastroesophageal Reflux
Stimulation of Sensation and Improvement in Swallowing Using Oral Capsaicin
This is a research study to learn more about whether capsaicin, a natural ingredient of chili peppers that makes them taste "hot", can improve swallowing function.
- Trial name
- NCT01053286
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Parkinson Disease, Huntington Disease
Group Drum-Based Music Therapy Intervention for Parkinson's Disease/Huntington's Disease
Participants in this study (18-89 years) with Parkinson's disease or Huntington's disease receive drum classes twice a week for 12 weeks (24 lessons).
- Trial name
- NCT05157074
- Testing
- Group Drumming Music Therapy
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Parkinson Disease, Postural Kyphosis, Lumbosacral Region
The Relationship of Trunk Position Sense and Spinal Posture With Balance in Parkinson's
The 4 main motor symptoms seen in Parkinson's patients are tremor, rigidity, postural instability and bradykinesia. In addition to these, another common symptom investigators encounter is balance problems.
- Conditions
- Parkinson Disease, Postural Kyphosis, Lumbosacral Region, Postural Kyphosis, Postural Lordosis, Lumbosacral Region
- Trial name
- NCT05233943
- Testing
- Spinal Mouse and Digital Inclinometer
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Multiple Sclerosis, Kinesiophobia
Evaluation of the Presence and Effects of Kinesiophobia in Multiple Sclerosis
The aim of this study was to evaluate the presence of kinesiophobia in multiple sclerosis and to investigate the effect of kinesiophobia on physical activity, functional status, quality of life and depression.
- Trial name
- NCT06167447
- Testing
- questionnaire and examination
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Gazi University
Attention Deficit Hyperactivity Disorder, Autistic Disorder
Characterization of Executive Functions and Patterns of Eye Movements in Children With Developmental Disabilities
The purpose of this study is to characterize the profile of executive functions and eye movements in several populations of children with developmental disabilities.
- Conditions
- Attention Deficit Hyperactivity Disorder, Autistic Disorder, Developmental Coordination Disorder
- Trial name
- NCT00716235
- Where
- Israel
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Neurologic Disorder, Parkinson Disease
High Intensity Functional Training for Individuals With Neurologic Diagnoses and Their Care Partners
Individuals with and without neurologic diagnoses greatly benefit from participation in regular exercise but the majority are physically inactive.
- Conditions
- Neurologic Disorder, Parkinson Disease, Spinal Cord Injuries, Spina Bifida
- Trial name
- SHIFT-AR (NCT05951985)
- Testing
- HIFT
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Arkansas Colleges of Health Education
Parkinson Disease and Hydrotherapy
Acute Effects of Strength Training and High Intensity Training on Functional and Biochemical Measurements of Individuals With Parkinson's Disease in Different Environments and Depths
Introduction: Parkinson's disease (PD) is the second most common neurodegenerative disease in the elderly. Chronic and progressive, it includes loss of dopamine, a neurotransmitter involved in the regulation of movement.
- Trial name
- NCT04863118
- Testing
- Strength training in shallow water and dry land, High-intensity training in shallow and deep water
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federal University of Health Science of Porto Alegre
Parkinson Disease
Support + High Intensity Functional Training for Parkinson's
Parkinson's is the fastest growing neurological disorder in the world. With more people living with Parkinson's than ever before, there is an urgent need for interventions that improve health and reduce disability.
- Trial name
- SHIFT-PD (NCT05225506)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Arkansas Colleges of Health Education
Traumatic Brain Injury, Stroke
Long-term Brain Stimulation of the Motor Ventral Thalamus (VOP/VIM) to Improve Motor Function
This study aims to recruit patients already implanted with Deep Brain Stimulation (DBS) for movement disorders to complete tasks assessing parameters of motor output, speech, and swallowing functions, both with and without…
- Conditions
- Traumatic Brain Injury, Stroke, Brain Disease, Movement Disorders (Incl Parkinsonism)
- Trial name
- NCT07056348
- Testing
- Deep Brain Stimulation (DBS) of the Motor Thalamus
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jorge Gonzalez-Martinez
Cognitive Dysfunction
Eye Movement Parameters and Cognitive Functions in Older Adults
Dementia most commonly occurs in elderly individuals, but currently there is still a lack of objective measurement methods that can detect cognitive impairment in older adults at an early stage.
- Trial name
- NCT07358598
- Where
- Taiwan
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- National Sun Yat-sen University
Obesity
Home-based Training in Obese Individuals
Generally, the enhancement of physical fitness depends on the optimal modulation of different physiological, technical or psychological stimuli and within the factors the would contribute to a decrease performance level, obesity…
- Trial name
- FITOB (NCT05773690)
- Testing
- Movement quality, Conventional Resistance Training
- Where
- Italy
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Huntington's Disease
Social Cognition in Huntington's Disease: Cognitive Study and Functional and Morphological Imaging
Huntington's disease is a rare genetic neurodegenerative disease. It is accompanied by movement disorders, cognitive and behavioral. The social behavior of patients are changed, affecting interpersonal relationships.
- Trial name
- COSIMH (NCT02550275)
- Testing
- neuropsychological test, MRI
- Where
- France
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Social Perception in Parkinson's Disease
Brain Mechanisms of Social Perception in Parkinson's Disease
Social cognition is a complex process that enables humans to interpret social information and behave appropriately in a social environment.
- Trial name
- Park Social (NCT06884722)
- Testing
- Behavioral task of social perception (stage 1), Functional magnetic resonance imaging: 3 Tesla magnetic resonance imaging (stage 2), Neurological and neuropsychological assessments
- Where
- France
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Pulmonary Disease, Chronic Obstructive, Postural; Defect
Determination of Body Awareness and the Functional Movement in Patients With COPD
The aim of this study is to investigate body awareness and functional movement in patients with Chronic Obstructive Pulmonary Disease (COPD) compared to healthy controls.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Postural; Defect, Movement, Abnormal, Pain
- Trial name
- NCT06298994
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Multiple Sclerosis
Improving Hand Movement and Coordination in People With Multiple Sclerosis Using Transcranial Magnetic Stimulation (TMS) and Muscle Electrostimulation (FES) To Support Manual Dexterity and Daily Function
The goal of this interventional study is to test whether combining transcranial magnetic stimulation (TMS) with functional electrical stimulation (FES) can improve hand and upper limb function in adults with Multiple Sclerosis…
- Trial name
- MANTRAStim (NCT07098273)
- Testing
- TMS and FES- based rehabilitation, FES-based rehabilitation
- Where
- 2 sites in Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS