Clinical trials: Movement Disorders, Functional
Parkinson Disease
Effects of Land and Water Physiotherapy on Motor Function in Parkinson's Disease
The aim of this study is to assess the effect of dry soil therapy and shallow water therapy on motor function in individuals with Parkinson's disease. Regarding the benefits, is there a difference between the therapies?
- Trial name
- NCT05866120
- Testing
- Physiotherapy on the ground, Aquatic physiotherapy
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Vitamin D Deficiency, Parkinson Disease
12 Weeks Vitamin D Supplementation and Physical Activity in PD Patients With DBS
Parkinson's disease (PD) is the second most frequently appearing neurodegenerative disease. It is a progressive disease of the central nervous system (CNS) and affects around 1% of people over 60 years old.
- Trial name
- NCT04768023
- Testing
- Juvit D3
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Medical University of Gdansk
Parkinson Disease
rTMS on Motor Function of Parkinson's Disease Patients With Different Phenotypes
In this study we wondered whether patients with different phenotypes of Parkinson's disease respond differently to the protocol of repetitive transcranial magnetic stimulation (rTMS) associated with physical therapy.
- Trial name
- NCT04116216
- Testing
- High frequency repetitive transcranial magnetic stimulation, Low frequency repetitive transcranial magnetic stimulation
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal de Pernambuco
Cerebral Palsy
Sensory Stimulation During CIMT
The long-term goal of this project is to assess the impact of the novel sensory stimulation technique in enhancing outcomes of constraint-induced movement therapy (CIMT) in children with cerebral palsy. This is a pilot project.
- Trial name
- NCT03558230
- Testing
- Standardized Constraint-Induced Movement Therapy, Vibration
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Medical University of South Carolina
Parkinson Disease
Smart Home-based Technology to Promote Functional Mobility Among Individuals With Parkinson's Disease
Many patients with Parkinson's disease suffer of gait disorder termed as "freezing of gait" (FOG). non-pharmacological approach such as applying external cues is effective in mitigating FOG events.
- Trial name
- NCT05211687
- Testing
- Smart-home for freezing of gait
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- University of Haifa
Dystonia, Parkinson Disease
Impact of a Standardized Music Therapy Protocol on the Quality of Life of Patients With Abnormal Movements Treated With Continuous Electrical Neuromodulation
The study of the impact of music on emotional, motor and cognitive aspects remains recent. Music therapy has experienced a major boom over the last half century thanks to neuroradiological techniques for investigating the brain…
- Conditions
- Dystonia, Parkinson Disease, Essential Tremor
- Trial name
- Music-QOL (NCT05214313)
- Testing
- Music Therapy
- Where
- France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Montpellier
Irritable Bowel Syndrome (IBS)
Effect of HMOs as Nutritional Support for Normal Bowel Movements in IBS Patients
This is an open labeled, one-armed real-world study in IBS-patients. All participants will receive active treatment for 12 weeks.
- Trial name
- GRIPS (NCT03550742)
- Testing
- Fuco-N-Tetraose
- Where
- United States
- Volunteers
- 317 people
- Sponsor
- Glycom, Inc.
Parkinson Disease
Exercise and Plasticity in Parkinson Disease
We will study the effects of intensive rehabilitation in PD on plasticity with a multimodal approach. We will define first, whether exercise in PD restores the potentiation of the motor cortex to normal levels with both 5 Hz-rTMS…
- Trial name
- NCT05786261
- Testing
- experimental group MIRT, EEG task rTMS, fMRI
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Pain, Sleep
Effects of Tactile Touch on Chronic Pain in Parkinson´s Disease
The Parkitouch study compared the effects on pain, sleep quality and HealthRelated Quality of Life (HRQoL) among 44 participants with Parkinson´s Disease for at least two years and chronic pain.The two groups were randomized to…
- Trial name
- NCT01734876
- Testing
- Tactile Touch, Rest To Music
- Where
- Sweden
- Volunteers
- 45 people
- Sponsor
- Region Jönköping County
Functional Neurological Disorders
Functional Neurological Disorders in Patients Admitted in Stroke Units
Functional neurological disorders are an important subgroup of patients with stroke mimics admitted to stroke unit.Their clinical profile and outcome are poorly known.
- Trial name
- NEUROFON (NCT04662372)
- Testing
- Description
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Multiple Sclerosis, Chronic Progressive, Multiple Sclerosis
MUSCLE - Nordic Walking in MUltiple SCLErosis
The aim of the study is to analyze the effects of Nordic Walking and free walking in the clinical-functional, postural balance, motor control, muscular echographic quality, and gait analysis (pendulum gait mechanism), in people…
- Conditions
- Multiple Sclerosis, Chronic Progressive, Multiple Sclerosis, Multiple Sclerosis, Primary Progressive, Multiple Sclerosis, Secondary Progressive
- Trial name
- MUSCLE (NCT05385731)
- Testing
- Nordic Walking (NWG), Free Walking (FWG), Health Education (HEG)
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Leonardo A. Peyré-Tartaruga
Functional Neurological Disorders
The Pathophysiology of Functional Neurological Disorders
Functional disorders, also called psychogenic or psychosomatic are very common, disabling and their costs to society are immense.
- Trial name
- NCT02905877
- Testing
- Behavioural study
- Where
- United Kingdom
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University College, London
Parkinson's Disease, Multiple Sclerosis
Blood Lactate Concentrations With and Without Exercise in Parkinson's Disease and Multiple Sclerosis Patients
Fatigue is one of the most common and debilitating symptoms experienced in Parkinson's Disease (PD) and Multiple Sclerosis (MS).
- Trial name
- PDMSLac (NCT02184494)
- Testing
- pro5 AIRdaptive Power Plate (Badhoevedorp, The Netherlands)
- Where
- 2 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Florida State University
Diabetes Mellitus Type 2, Impaired Balance in Elderly
Improvement Through Movement - Balance Control and Somatosensory Function in People With Diabetes Mellitus Type 2
This study focuses on improving balance control and somatosensory functions in individuals aged 60 years and older with diabetes mellitus tyoe 2 (DMT2).
- Conditions
- Diabetes Mellitus Type 2, Impaired Balance in Elderly, Somatosensory Disorders, Balance Control in Elderly
- Trial name
- NCT07786194
- Testing
- Balance control and exercise training, Relaxation and exercise training
- Where
- Belgium
- Volunteers
- 48 people
- Sponsor
- Universiteit Antwerpen
Parkinson Disease, Multiple Sclerosis
Functional Exercise in Virtual Environment for Persons With Multiple Sclerosis or Parkinson's Disease
The aim of the study is to optimise the hand dexterity exercising program in virtual reality (VR) for patients with multiple sclerosis and Parkinson's disease.
- Trial name
- MEFA (NCT04266444)
- Testing
- Exergaming in virtual environment
- Where
- Slovenia
- Volunteers
- 108 people
- Sponsor
- University Rehabilitation Institute, Republic of Slovenia
Parkinson's Disease (PD)
Observational Study Evaluating Robotic Spinal Mobilization in 16 Parkinson's Disease Participants. The Study Recorded Changes in Mobility, Sit-to-stand Performance, and Pain Scores After a 2-week Intervention With the BackHug Device.
The goal of this completed observational pilot study was to evaluate the immediate and short-term clinical effects of robotic spinal mobilization on motor and non-motor symptoms in community-dwelling adults with Parkinson's…
- Trial name
- NCT07384364
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- Pacla Medical Limited
Malignant Brain Tumors
Magnetic Resonance (MR) Guided Focused Ultrasound in the Treatment of Brain Tumors
Focused Ultrasound Focused ultrasound is an attractive method for non-invasive thermal ablation of soft tissue tumors. Treatment begins by acquiring a series of MR images of the target organ.
- Trial name
- FUS-Tumor (NCT01698437)
- Testing
- Non-invasive intervention with focused ultrasound (ExAblate 4000)
- Where
- Switzerland
- Volunteers
- 3 people
- Sponsor
- University Children's Hospital, Zurich
Essential Tremor, Neuromodulation
Ultrasound Neuromodulation in Essential Tremor
This study is being done to test whether low-intensity focused ultrasound (LIFU) (low energy sound waves) cause temporary changes in brain activity and behavior when directed at particular parts of the brain.
- Trial name
- UNMET (NCT06610877)
- Testing
- Focused ultrasound neuromodulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Francisco
Parkinson Disease
Improvisational Dance for Parkinson Disease
The long-term goal of this work is to maintain or improve daily function of people with PD by addressing cognition. The overall objective is to discover interventions that aid in cognitive functioning.
- Trial name
- NCT04354298
- Testing
- Improvisational Dance Class
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Movement Disorders (Incl Parkinsonism), Parkinsonian Disorders
Effect of Motor Function, Depression and Sleep Quality on Attention in Parkinson's Disease
Our study was planned to analyze motor function, endurance and sleep attention information in Parkinson's patients with detailed and objective measurements.
- Conditions
- Movement Disorders (Incl Parkinsonism), Parkinsonian Disorders, Attention Impaired, Movement Disorders, Functional
- Trial name
- NCT06283043
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Inonu University