Clinical trials: Multimorbidity
Multimorbidity
Evaluating the Accuracy of an Integrated Vital Sign Measurement Platform
Partners Connected Health will conduct a clinical validation study to evaluate the accuracy of measurement for each vital sign with the Vital Moto Mod platform, compared to appropriate reference devices used in the hospital…
- Trial name
- NCT03589716
- Testing
- Vital Moto Mod, Welch Allyn Connex Spot Vital Signs Monitor, Capnostream 20 Portable Bedside Capnograph
- Where
- United States
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Multimorbidity, Integrated Care
TimelyCare - A Proactive Primary Care Model: Delivering the Right Care at the Right Time for Individuals at Risk of High Care Consumption
Healthcare systems face persistent challenges in providing coordinated, proactive care for individuals with complex health needs, resulting in high vulnerability to fragmented care, acute clinical deterioration, and frequent…
- Conditions
- Multimorbidity, Integrated Care, Primary Care Patients With Chronic Conditions, Coordination, Administrative
- Trial name
- NCT07899723
- Testing
- Timely Care,
- Where
- Sweden
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Linnaeus University
Sleep Disordered Breathing (SDB), Sleep Apnea
Sleep Disordered Breathing and Multimorbidity: The Xiangya SDB Cohort Study
Sleep disordered breathing (SDB) is one of the most common sleep disorders, including obstructive sleep apnea (OSA), central sleep apnea (CSA), sleep-related hypoventilation, hypoxemia, etc., with OSA being the most prevalent.
- Conditions
- Sleep Disordered Breathing (SDB), Sleep Apnea, Cardiometabolic Diseases, Multimorbidity
- Trial name
- NCT06755840
- Where
- China
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Multimorbidity, General Practice (GP), Primary Care Settings
Exploring the Multimorbidity Burden in Primary Care in Romania
Multimorbidity, the coexistence of two or more chronic conditions, is a growing challenge in primary care, significantly impacting healthcare systems worldwide.
- Conditions
- Multimorbidity, General Practice (GP), Primary Care Settings, Specialist Referral
- Trial name
- MULTIMORB-PC-R (NCT06876558)
- Where
- Romania
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Internist.Ro
Chronic Respiratory Diseases, Cardiovascular and Cerebrovascular Diseases
Chinese Population Health and Multimorbidity Study
The Chinese Population Health and Multimorbidity Study (CPHMS; initially named China Pulmonary Health Study, CPHS) was a large-scale epidemiological survey designed to investigate the pulmonary health of Chinese adults aged 20…
- Conditions
- Chronic Respiratory Diseases, Cardiovascular and Cerebrovascular Diseases, Malignant Tumors, Endocrine and Metabolic Diseases
- Trial name
- CPHMS (NCT07026370)
- Where
- China
- Volunteers
- 50,991 people, healthy volunteers welcome
- Sponsor
- China-Japan Friendship Hospital
Chronic Diseases
Evaluate the Effectiveness of a Virtual Community of Practice
Objective: To evaluate and compare the effectiveness and cost-effectiveness of a Virtual Community of Practice (VCoP) via a web-based application versus individual and self-administered online education to improve the activation…
- Trial name
- NCT06046326
- Testing
- virtual community of practice
- Where
- 3 sites in Spain
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Gerencia de Atención Primaria, Madrid
Multimorbidity
Physical Activity Modifies Exercise Responsiveness
Exercise is the cornerstone of rehabilitation and an essential part of treatment plans for many chronic conditions; however, our understanding of why certain individuals respond positively to exercise while others do not remains…
- Trial name
- NCT07792967
- Testing
- SLIMM - Sit less, interact, move more, PB125
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Chronic Kidney Diseases, Sarcopenia
Multimorbidity and Sarcopenia Feasibility Study in Chronic Kidney Disease
The aim of this research study is to look at the body composition (such as muscle and fat) in people with chronic kidney disease (CKD) and comparing it with body composition is people without CKD.
- Trial name
- MaSS-CKD (NCT06109662)
- Testing
- Cystatin C eGFR, Bioimpedance Analysis (Body composition analysis)
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospitals of Derby and Burton NHS Foundation Trust
HIV (Human Immunodeficiency Virus)
Multimorbidity and Polypharmacy in People With HIV vs. the General Population in the Basque Country
People living with HIV now have a life expectancy similar to that of the general population, thanks to major advances in antiretroviral treatment.
- Trial name
- NCT07621224
- Testing
- No intervention
- Volunteers
- 12,546 people, healthy volunteers welcome
- Sponsor
- Biogipuzkoa Health Research Institute
Multimorbidity, Multiple Chronic Conditions
Effect of Aerobic Training on the Health Parameters of Postmenopausal Women With Multimorbidity
People affected by multiple chronic diseases have a greater chance of hospitalization, longer hospital stays, worse general health, worse physical and mental function and lower functional capacity, with an average risk of 50% of…
- Conditions
- Multimorbidity, Multiple Chronic Conditions, Hypertension, Dyslipidemias
- Trial name
- NCT05075902
- Testing
- Aerobic training
- Where
- Brazil
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Federal University of Uberlandia
Fatigue, Depression
Health Literacy Assessment and Intervention to Reduce Disparities: FLIGHT/VIDAS II
The purpose of this study will to be to evaluate the effects of a mobile intervention focused on improving the chronic disease self management skills of individuals with low health literacy.
- Conditions
- Fatigue, Depression, Pain, Sleep Wake Disorders
- Trial name
- FV2 (NCT02922439)
- Testing
- Tailored Intervention, Control Intervention
- Where
- United States
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Chronic Conditions, Multiple, Aging
Physical Literacy and Rehabilitation
With the aging population, the prevalence of chronic conditions continues to rise, affecting 1/3 of Canadians. The promotion of physical literacy, defined as "the motivation, confidence, physical competence and knowledge, to take…
- Conditions
- Chronic Conditions, Multiple, Aging, Mobility Limitation
- Trial name
- NCT04494711
- Testing
- Physical Functional Literacy for Adults
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Julie Richardson
Chronic Obstructive Pulmonary Disease, Heart Failure
Multidimensional Approach for COPD and High Complexity
The MACH Study trial will examine the impact on high complexity COPD patients of a multidimensional approach (moderate-intensity physical activity program and clinic-therapeutic re-evaluation of the participants)
- Conditions
- Chronic Obstructive Pulmonary Disease, Heart Failure, Chronic Disease
- Trial name
- MACH (NCT04986332)
- Testing
- Physical activity program, Global therapeutic remodeling
- Where
- Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo
Multimorbidity, Heart Failure
Effectiveness of a Multimodal Intervention With Simulation for Learning Home Health Nursing Care of Patients With Multimorbidity and Heart Failure
The goal of this clinical trial is to evaluate the efficacy of a multimodal intervention with high-fidelity simulations on home health nursing in improving the care of multipathological patients with heart failure in nursing…
- Trial name
- NCT06855719
- Testing
- Training in high-fidelity simulation and knowledge of care protocols in patients with multimorbidity and heart failure
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Cadiz
Myopia, Mental Health
Intervention for Preventing Myopia and Multimorbidity in Children
This study aims to develop and evaluate a scalable, hybrid intervention model for the co-prevention of myopia, obesity, and mental health issues among children.
- Conditions
- Myopia, Mental Health, Cardiovascular Health Status
- Trial name
- NCT07294222
- Testing
- Standard School Health Education, Multi-component Health Promotion Package
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Fangbiao Tao
Multimorbidity, Healthy
Pilot Trial of Fisetin in Healthy Volunteers and Older Patients With Multimorbidity
The accumulation of senescent cells with age is a central mechanism that contributes to the development of chronic diseases, primarily by driving systemic chronic inflammation.
- Trial name
- Fisetin HIGH (NCT06431932)
- Testing
- Fisetin
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ove Andersen
to Evaluate Association Between Complexity, Multiple Illnesses and Mortality
How Complexity and Multiple Illnesses Affect Hospitalized Patients' Health: A Multicenter Study
The goal of this observational study is to evaluate the association between complexity and multiple illnesses of adult hospitalized internal medicine patient and mortality.
- Trial name
- SPIR (NCT06872632)
- Where
- 21 sites in Italy
- Volunteers
- 2,326 people, healthy volunteers welcome
- Sponsor
- Società Italiana di Medicina Interna
Multimorbidity
Personal Resources of Elderly People With Multimorbidity
PREFER II aims at developing psychological targeted theory- and evidence-based intervention components, which support older people with multiple illnesses in performing more physical activity.
- Trial name
- PREFER (NCT01577134)
- Testing
- Social-cognitive resource intervention, no intervention
- Where
- Germany
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- German Centre of Gerontology
Multimorbidity
Co-design of a Seamless Person-centered Intervention to Optimize Medication Use Across Healthcare Levels
Multiple long term conditions entails various needs for complex medication treatment, which is a huge clinical challenge considering medication interactions and disease-medication interactions.
- Trial name
- CIRCLE (NCT05421143)
- Where
- Norway
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Malin Olsen Syversen
Maternal Cardiometabolic Health, Infertility
St Mary's Assisted Reproductive Technology and Cardiometabolic Health: Modifiable Targets for Multimorbidity Prevention (START-HEALThY)
The main causes of death in women are conditions affecting the heart and blood vessels (cardiovascular disease, CVD). Women who have difficulties getting pregnant (infertility) may be at increased risk, but the reasons for this…
- Conditions
- Maternal Cardiometabolic Health, Infertility, Assisted Reproductive Technology, Cardiovascular Health
- Trial name
- START-HEALThY (NCT07173569)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Manchester