Clinical trials: Muscle
Muscle Damage
Sex Differences in Muscle Damage Following Resistance Exercise With or Without Milk Protein Ingestion
Purpose: To investigate the impact of milk protein ingestion on resistance exercise-induced muscle damage in untrained males and females.
- Trial name
- EIMD-MILK (NCT04986150)
- Testing
- Resistance exercise
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Durham University
Contraceptives, Oral, Sex Hormone
Oral Contraceptive vs Menstrual Cycle Ex Vivo Model
Despite comprising half the population, females are often left out of muscle research due to the impact of changing hormones during the menstrual cycle and when using oral contraceptives.
- Trial name
- OCEV (NCT06124274)
- Testing
- Protein tracer drink
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Healthy
Effects of Foam Rolling Prior to PNF Stretching on Hamstring Flexibility and Thigh Skin Temperature in Healthy Subjects
There is no study investigating the hamstring flexibility and skin temperature after combined warm-up techniques especially PNF and foam rolling.
- Trial name
- PNF (NCT04718363)
- Testing
- PNF stretching, Non-vibration foam rolling prior to PNF stretching, Vibration foam rolling prior to PNF stretching
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Trigger Finger
Endoscopic Trigger Finger Release
The purpose of this study is to compare recovery, scar, and patient satisfaction after retrograde endoscopic trigger finger release versus the standard open surgical treatment.
- Trial name
- NCT03883477
- Testing
- Endoscopic Release, Standard Open Release
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Sports Physical Therapy
Big Toe Muscles Strengthening Exercises With and Without Neuromuscular Training Among Runners
The big toe in relation to the other toes is responsible for a much greater percentage of foot and body stabilization as well as forward propulsion.
- Trial name
- NCT06986681
- Testing
- Big toe muscles strengthening exercises, Big toe muscles strengthening exercises with neuromuscular training
- Where
- Pakistan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Sarcopenia
Insulin and Sarcopenia in the Elderly
Muscle loss with aging is a significant contributor to disability in older people. Our general hypothesis is that loss of muscle with aging, known as sarcopenia, may be due to inability of muscle to grow in response to insulin.
- Trial name
- NCT00690534
- Testing
- Insulin Regular, L-NMMA, Sodium Nitroprusside
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Muscle Strength
Effects of Vibrations on the Biceps Brachii Muscle and Grip Strength
It has been suggested that applying acute vibration exercises enhances muscle force, like several weeks of resistance training. The present study investigated the effects of local vibration with two different frequencies on…
- Trial name
- NCT05523232
- Testing
- Vibration training with 42 Hz, Vibration training with 63 Hz
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King Saud University
Lymphoma Patients
Progressive Muscle Relaxation Exercises on Sleep, Fatigue, Pain in Lymphoma Patients
With regular practice, relaxation has been found to have many benefits such as reducing sensitivity to pain and fatigue, facilitating the transition to sleep, and improving quality of life.
- Trial name
- NCT06920095
- Testing
- Progressive muscle relaxation exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Sabahattin Zaim University
Stroke
Evaluation of BOTOX® With Rehabilitation Therapy for the Treatment of Wrist and Hand Spasticity in Post-Stroke Patients
The present study is designed to determine the safety and effectiveness of injections of BOTOX® in spastic muscles of the arm and hand compared with injections of saline (which would do nothing) when combined with rehabilitation…
- Trial name
- Botox/Rehab (NCT00565201)
- Testing
- Botox and rehab
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Emory University
Chronic Pain, Pain, Musculoskeletal
Physical Therapy Integrated With Mindfulness for Patients With Chronic Pain and Opioid Treatment
This study will use multiple methods to assess the feasibility of conducting a fully powered multisite clinical trial to test the effectiveness of integrating mindfulness-based interventions into physical therapy for patients…
- Conditions
- Chronic Pain, Pain, Musculoskeletal, Opioid Use, Physical Therapy
- Trial name
- PT-IN-MIND (NCT05875207)
- Testing
- Mindfulness based practice, Control/Standard Physical Therapy
- Where
- 2 sites in United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University of Utah
Neck Pain, Back Pain
Cervical and Lumbal Region Muscle Architecture in Individuals With Low Back and Neck Pain
Back or neck problems often begin with an injury and often include a muscle injury. Injury of muscle fibers can occur due to trauma, disease, myotoxic agents, inflammatory processes, and intense exercise.
- Trial name
- NCT05206136
- Testing
- Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Recovery
Influence of Specific Collagen Peptides on Recovery After Exercise Induced Muscle Damage
The present study aims at investigating the potential influence of specific collagen peptides on recovery after exercise induced muscle damage with focus on long-term effects.
- Trial name
- NCT05220371
- Testing
- Collagen, Concurrent training
- Where
- Austria
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Respiratory Insufficiency
"Inspiratory Muscle Training in Older Women"
Objective: To evaluate the effectiveness of two protocols of inspiratory muscle training (IMT) in older women to improve respiratory strength, spirometric parameters and dyspnea.
- Trial name
- NCT03827356
- Testing
- Inspiratory muscle trainer (IMT)
- Where
- Spain
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Knee Osteoarthritis
Electromyographic Biofeedback on Performance of Vastus Medialis Oblique Muscle in Knee Osteoarthritis
This study intends to determine the Effects of Electromyographic biofeedback on performance of vastus medialis oblique muscle in knee osteoarthritis.
- Trial name
- NCT04194853
- Testing
- Electromyographic Biofeedback, Quadriceps Isometric exercises
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Healthy Volunteers
Effects of Running Shoe Sole Hardness on Vibration and Neuromuscular Fatigue During a Half-marathon Run on a Treadmill
During running, each contact between the foot and the ground causes an impact. Ground reaction forces (GRF) are considered as an input into the musculoskeletal system.
- Trial name
- FAT-VIB (NCT06110637)
- Testing
- "hard shoes" runners evaluation, "Soft shoes" runners evaluation
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Temporomandibular Disorder
Analgesic Effects of LED Light on Temporomandibular Disorders.
Low intensity laser therapy (LILT) has been widely applied in pain relief in several clinical situations. With the advent of new LED-based (light emitting diode) light sources, the need of further clinical experiments aiming to…
- Trial name
- LED/TMD (NCT01873937)
- Testing
- Red LED, INFRARED LED, LASER
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Sarcopenia
Understanding Loss of Muscle Mass and Function
Sarcopenia is a loss of muscle mass and function that develops during aging. But sarcopenia is also observed in several other conditions: chronic diseases, cancers, viral infections, renal / respiratory insufficiency, immobility…
- Trial name
- SAMANTHA (NCT04004039)
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Hypertension
L-citrulline Supplementation, Cold Exposure, & Post-Exercise Muscle Ischemia
Cardiovascular disease (CVD) continues to be the major cause of morbidity and mortality in western countries. It has been shown that CVD events are known to be higher in the winter than in the summer.
- Trial name
- NCT02104375
- Testing
- L-citrulline
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Florida State University
Healthy Adult Participants
Geko® T3 One vs Two Study
The primary objective of this study to assess the haemodynamic effects of unilateral and bilateral geko® T3 stimulation on lower-limb circulation, measured by femoral artery and vein blood flow.
- Trial name
- NCT07849257
- Testing
- NMES
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Kieron.Day
Muscle Protein Synthesis, Whole-body Protein Balance
Essential Amino Acids and Protein Kinetics During Caloric Deprivation
The amount of essential amino acids (EAA) necessary to maximally stimulate muscle protein synthesis and optimize whole-body net protein balance during caloric deprivation has not been determined.
- Trial name
- NCT03372928
- Testing
- Standard EAA, High EAA
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine