Clinical trials: Muscle Disorders
Myofascial Pain - Dysfunction Syndrome of TMJ
Efficiency of Botulinum Toxin type-a in the Management of the Myofascial Pain
Study Title: Investigation of the Relationship Between Clinical Outcomes and Pain Mediators in the Treatment of Masticatory Muscle Disorders Associated with Myospasm Using Onabotulinum Toxin A Study Importance: Temporomandibular…
- Trial name
- NCT06840730
- Testing
- Botulinum Toxin A (Botox )
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Hacettepe University
Epicondylitis
Platelet Rich Plasma (PRP) in Chronic Epicondylitis
Background Tendinopathy is a difficult problem to manage and can result in significant patient morbidity. Currently, the clinical use of PRP in painful tendons is widespread but its efficacy remains controversial.
- Trial name
- B-PRPtendon (NCT01945528)
- Testing
- US-guided tenotomy with PRP, US-guided tenotomy with lidocaine
- Where
- 2 sites in Spain
- Volunteers
- 86 people
- Sponsor
- Jose Ignacio Martin
Advanced Lung Disease, Lung Transplant
Progressive Rehabilitation Therapy in Patients With Advanced Lung Disease
The International Society of Heart and Lung Transplantation Registry data shows that there is a growing population of critically ill patients with advanced lung disease undergoing lung transplantation.
- Conditions
- Advanced Lung Disease, Lung Transplant, Extracorporeal Membrane Oxygenation
- Trial name
- NCT03562728
- Testing
- MRP and NMES(neuromuscular electric stimulation), Standard of Care
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Maryland, Baltimore
Post-COVID-19 Syndrome, Dyspnea
Home-Based Respiratory Muscle Strength Training Program for Individuals With Post-COVID-19 Persistent Dyspnea
To evaluate the extent to which a 12-week respiratory rehabilitation program consisting of inspiratory and expiratory breathing exercises compared to expiratory breathing exercises alone will help to improve shortness of breath…
- Trial name
- NCT06091280
- Testing
- Respiratory Muscle Strength Trainers
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of South Florida
Chronic Pain, Anxiety
Nu-V3 Non-Invasive Nerve Stimulation Device Trial for Chronic Pain, Anxiety, Depression, Sleeplessness
The Nu-V3 Clinical Study is a prospective, single-arm, open-label, multi-center study using the Nu-V3 cranial nerve stimulation treatment device in patients with chronic pain, anxiety, depression, and/or sleeplessness.
- Conditions
- Chronic Pain, Anxiety, Depression, Sleeplessness
- Trial name
- Nu-V3 (NCT05335980)
- Testing
- Nu-V3
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Nu-Life Solutions
Pulmonary Disease, Chronic Obstructive
Abdominal Functional Electrical Stimulation to Reduce Hyperinflation in Chronic Obstructive Pulmonary Disease Patients
This is an early feasibility study to investigate whether transcutaneous electrical stimulation applied to the abdominal wall muscles synchronous with voluntary exhalation can be used to support ventilation and affect…
- Trial name
- NCT02035228
- Testing
- Abdominal Stimulation - low / early, Abdominal stimulation - low/late, Abdominal Stimulation - low/full
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Liberate Medical
Cerebral Palsy
Effects of PEDAL Program With and Without EMS On Mobility And Gait In Children With Cerebral Palsy
PEDAL is a program that focuses on juvenile endurance and limb building for kids with cerebral palsy. Studying how PEDAL with and without Electrical Muscle Stimulation (EMS) affects these metrics in an effort to determine whether…
- Trial name
- NCT06460311
- Testing
- PEDAL and EMS, PEDAL
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Bladder Cancer
Comparison of Medical and Surgical Treatments of Benign Prostate Hyperplasia in Patients Who Have Low Grade Non Muscle Invasive Bladder Cancer for Tumour Recurrence and Progression
The purpose of this study is to compare medical and surgical treatments of benign prostate hyperplasia in patients who have non muscle invasive bladder cancer for tumour recurrence and progression.
- Trial name
- NCT02443844
- Testing
- Transurethral Resection, Tamsulosin
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Diskapi Teaching and Research Hospital
Tennis Elbow
Treatment of Lateral Epicondylitis With a Percussive Therapy Device
The purpose of this study is to assess the efficacy of using a percussive therapy device in addition to physical therapy to treat acute tennis elbow
- Trial name
- NCT05723809
- Testing
- Percussive Therapy Device, Physical Therapy
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Cedars-Sinai Medical Center
Occupational Health, Sick Leave
Effects of Regulatory Tools on Work Environment and Employee Health
This study evaluates the effects of the Labour Inspection Authority's regulatory tools on workplace exposures to prevent employee ill health.
- Conditions
- Occupational Health, Sick Leave, Occupational Exposure
- Trial name
- NCT03855163
- Testing
- Inspection visits, Guidance workshops, Online risk assessment tool
- Where
- 130 sites in Norway
- Volunteers
- 2,555 people, healthy volunteers welcome
- Sponsor
- National Institute of Occupational Health, Norway
Pulmonary Disease, Chronic Obstructive, Mitochondrial Alteration
High Intensity Interval Training and Muscle Adaptations During PR
Pulmonary rehabilitation (PR) is a validated treatment in patients with Chronic Obstructive Pulmonary Disease (COPD), improving exercise tolerance, quality of life and dyspnea.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Mitochondrial Alteration, Oxygen Deficiency
- Trial name
- MITOXITRAIN (NCT05858463)
- Testing
- Modality of exercise training
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Clermont-Ferrand
Pes Cavus, Pes Planus
Analysing The Impact of Foot Arch Height on Leg Muscle Tone and Balance in Young Adults.
The goal of this observational study is to explore how the shape of the foot arch affects muscle tone, strength, and balance in healthy young adults aged 18-25, of all genders. The main questions it aims to answer are: 1.
- Conditions
- Pes Cavus, Pes Planus, Muscle Tone, Balance Assessment
- Trial name
- NCT07764393
- Testing
- Arch Height Index, Foot Posture Index, Single Leg Stance
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istinye University
Muscular Dystrophy, Duchenne
Phase 1/2 Study in Boys With Duchenne Muscular Dystrophy
The MoveDMD study is a 3-part, Phase 1/2, multi-site study to evaluate the safety, efficacy, pharmacokinetics (PK) and pharmacodynamics (PD) of edasalonexent (also known as CAT-1004) in pediatric patients with a genetically…
- Trial name
- MoveDMD® (NCT02439216)
- Testing
- Edasalonexent
- Where
- 5 sites in United States
- Volunteers
- 31 people
- Sponsor
- Catabasis Pharmaceuticals
Prediabetes, Obesity
Veterans Achieving Weight Loss and Optimizing Resilience-Using Protein
Diabetes is a major health concern in obese older Veterans, especially in those who are African American. The negative impact of diabetes on muscle and physical function contributes to metabolic as well as physical decline and is…
- Trial name
- VALOR-UP (NCT03835416)
- Testing
- Foods rich in high quality protein
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- VA Office of Research and Development
Spinal Muscular Atrophy
An Open-label Safety, Tolerability, and Dose-range Finding Study of Nusinersen (ISIS 396443) in Participants With Spinal Muscular Atrophy (SMA)
This objectives of this study are to evaluate the safety, tolerability, and pharmacokinetics of a single dose of nusinersen (ISIS 396443) administered intrathecally to participants with Spinal Muscular Atrophy (SMA).
- Trial name
- SMNRx (NCT01494701)
- Testing
- nusinersen
- Where
- 4 sites in United States
- Volunteers
- 28 people
- Sponsor
- Biogen
Musculoskeletal Diseases, Depression
Physical Activity Levels and Musculoskeletal Health Among Health Science Academicians at Istanbul Aydin University
This study aims to investigate the relationship between physical activity levels and posture, sleep quality, depression, and musculoskeletal system problems among academic staff working in the health sciences field at Istanbul…
- Conditions
- Musculoskeletal Diseases, Depression, Sleep Wake Disorders, Posture
- Trial name
- PA-ACAD-IAU (NCT07445100)
- Testing
- Observational Data Collection
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Tennis Elbow
Diacutaneous Fibrolysis on Lateral Epicondylitis
Diacutaneous Fibrolysis (DF) is a manual method of treatment, usually adjuvant, addressed to the mechanical pain of the locomotor system.
- Trial name
- NCT02343809
- Testing
- Actual Diacutaneous Fibrolysis, Protocolized Physiotherapy
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Duchenne's Muscular Dystrophy (DMD)
L-citrulline and Metformin in Duchenne's Muscular Dystrophy
The purpose of the study is to show that the intake of L-citrulline and metformin improves muscle function and delay of progression in patients with Duchenne's muscular dystrophy.
- Trial name
- NCT01995032
- Testing
- 750 mg metformin and 7.5 g L-citrulline daily p.o.
- Where
- Switzerland
- Volunteers
- 47 people
- Sponsor
- University Hospital, Basel, Switzerland
Neck Pain, Posterior, Headache
Dry Needling of the M. Obliquus Capitis Inferior on Rotational Mobility and Headache Related Outcome Measures in CH.
An experimental study will be conducted to evaluate the effect of dry needling on the M. Obliquus capitis inferior on rotational mobility and headache realted outcome measures in patients with cervicogenic headache.
- Conditions
- Neck Pain, Posterior, Headache, Mobility Limitation
- Trial name
- NCT05074381
- Testing
- Dry Needling
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- University Ghent
Diabetes Complications
Collagen-povidone for Diabetic Seniors' Tenosynovitis
Diabetes affects 415 million adults globally, leading to hand issues. Povidone collagen shows promise in managing tenosynovitis. A clinical trial was conduced to compared its efficacy in adults over 60.
- Trial name
- NCT06396819
- Testing
- collagen-povidone solution
- Where
- Mexico
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
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