Clinical trials: Muscle Fatigue
LONG-COVID, Post-acute Sequelae of COVID-19
Skeletal Muscle in PASC and ME/CFS Patients
Rationale: A common feature in patients with Post-Acute Sequelae of SARS-CoV-2 Infection (PASC) and Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) are skeletal muscle-related symptoms, such as muscle pain, weakness…
- Conditions
- LONG-COVID, Post-acute Sequelae of COVID-19, ME/CFS
- Trial name
- NCT05225688
- Testing
- Bike exertion test
- Where
- Netherlands
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Electrical Stimulation
Effect of Femoral Quadriceps Muscle Length on Fatigue Induced by Neuromuscular Electrical Stimulation
This study aims To investigate the effects of Quadriceps femoris muscle length on neuromuscular fatigue induced by NMES, muscle performance, discomfort and peripheral oxygen extraction.
- Trial name
- NCT05905406
- Testing
- Electrical estimulation
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Brasilia
Muscle Fatigue
Microcurrent Therapy and the Post-Exercise Physiological Response (MENS_PE)
The goal of this clinical trial is to find out whether microcurrent therapy changes blood levels of creatine kinase, a marker of muscle stress, during the first 48 hours after exercise in military personnel.
- Trial name
- MENS_PE (NCT07877337)
- Testing
- Microcurrents Therapy
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Healthy Volunteers, Muscle Fatigue
Effects of Recoverben® on Recovery After Exhaustive Exercise
The aim of the study is to investigate a pre and post workout supplementation (15 days) with Recoverben® , a Aloysia citriodora extract on recovery after exhaustive exercise.
- Conditions
- Healthy Volunteers, Muscle Fatigue, Muscle Soreness
- Trial name
- NCT02923102
- Testing
- Aloysia citriodora extract, Maltodextrin
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Vital Solutions GmbH
Fatigue, Inflammation
Effects of Post-exercise Protein Supplementation in Young Athletes
This randomised double blind, placebo-controlled study examined the effects of post-exercise consumption of whey protein (PRO) or carbohydrate (CHO) on performance recovery, muscle damage and inflammatory cytokine responses…
- Conditions
- Fatigue, Inflammation, Bone Resorption
- Trial name
- NCT04114045
- Testing
- Experimental:Whey protein, Active Comparator: Isoenergetic control - Carbohydrate
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brock University
Chronic Fatigue Syndrome
High-tech Acupuncture for Treatment of Chronic Fatigue Syndrome
1. To study the relationship between Chronic Fatigue Syndrome (CFS) and heart rate (HR) and its variability (HRV). 2. To compare the curative effects and the HR/HRV indices between applicationa of different acupoints as well as…
- Trial name
- NCT02924831
- Testing
- Acupuncture, moxibustion
- Where
- China
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Hubei Provincial Collaborative Innovation Center of Preventive Treatment by Acupuncture and Moxibust
Phase Angle
Phase Angle as a Marker of Muscle Damage, Muscle Fatigue and Inflammation, After Eccentric Exercise
The purpose of this study will be to assess the effectiveness of bioimpedance device (BIA) as a safe, rapid, and non-invasive method of analyzing muscle damage induced by high intensity induced eccentric exercise as an…
- Trial name
- NCT05583500
- Testing
- Experimental: Single group: excentric exercise protocol
- Where
- Spain
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidad Francisco de Vitoria
Chronic Fatigue Syndrome
Exertional Exhaustion in Chronic Fatigue Syndrome
Post-exertional malaise was modeled by having Chronic Fatigue Syndrome (CFS) and sedentary control subjects perform submaximal exercise on 2 consecutive days with objective changes in brain function measured by magnetic resonance…
- Trial name
- NCT03567811
- Testing
- Submaximal bicycle exercise stress test on Days 1 and 2
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Athletic Performance, Muscle Fatigue
Whole-Body Photobiomodulation Use in Professional Soccer Players During a State Championship
This study aims to investigate the effects of whole-body photobiomodulation on professional soccer players during a state championship.
- Conditions
- Athletic Performance, Muscle Fatigue, Muscle Strength, Sports
- Trial name
- WBPBM-PSC (NCT07224646)
- Testing
- Whole-Body Photobiomodulation (PBM) (Active PBM)
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Exercise-Induced Fatigue, Muscle Fatigue
Effect of Lactobacillus Plantarum GKK1 Supplementation on Anti-fatigue Health Effects
Title: Effect of Lactobacillus plantarum GKK1 Supplementation on Anti-Fatigue Health Effects: A Randomized, Double-Blind, Placebo-Controlled Trial This study aims to investigate the effects of Lactobacillus plantarum GKK1…
- Conditions
- Exercise-Induced Fatigue, Muscle Fatigue, Sports Performance, Fatigue Recovery
- Trial name
- GKK1-Fatigue (NCT06893549)
- Testing
- Lactobacillus plantarum GKK1 Probiotic
- Where
- Taiwan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Taiwan Sport University
Healthy
Improving Motor Skills: The Role of Music and Encouragement
This study used a randomised crossover design to analyse the effect of three different experimental interventions - i.e. standard conditions, music and verbal encouragement - on performance in an isometric endurance task…
- Trial name
- NCT06380088
- Testing
- Isometric Task
- Where
- Italy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Universita degli Studi di Genova
Lymphoma Patients
Progressive Muscle Relaxation Exercises on Sleep, Fatigue, Pain in Lymphoma Patients
With regular practice, relaxation has been found to have many benefits such as reducing sensitivity to pain and fatigue, facilitating the transition to sleep, and improving quality of life.
- Trial name
- NCT06920095
- Testing
- Progressive muscle relaxation exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Sabahattin Zaim University
Chronic Fatigue Syndrome
Use of Sildenafil (Viagra) to Alter Fatigue, Functional Status and Impaired Cerebral Blood Flow in Patients With CFS
Use of Viagra to Alter Symptoms in Patients with Chronic Fatigue Syndrome (CFS)
- Trial name
- NCT00598585
- Testing
- Sildenafil (Viagra)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Charles Drew University of Medicine and Science
Fibromyalgia, Chronic Fatigue Syndrome
Influence of Co-diagnosis of Chronic Fatigue Syndrome in Patients With Fibromyalgia.
The purpose of this study is to evaluate differences in neuroimmunoendocrine response and quality of live in patients diagnosed with Fibromyalgia, with or without a co-diagnosis of Chronic Fatigue Syndrome.
- Conditions
- Fibromyalgia, Chronic Fatigue Syndrome, Comorbidities and Coexisting Conditions
- Trial name
- NCT05323838
- Testing
- Subjective quality of live, Blood extraction, Accelerometry
- Where
- Spain
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
ME/CFS, Fibromyalgia (FM)
Whole-body Cryotherapy in Those With Chronic Fatigue: A Feasibility Study
Chronic fatiguing illnesses such as Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), Fibromyalgia, and Long COVID are becoming a major global health challenge.
- Conditions
- ME/CFS, Fibromyalgia (FM), Long-COVID, Control Group
- Trial name
- NCT07874217
- Testing
- Cryotherapy
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oxford Brookes University
Post-Acute COVID-19 Syndrome, ME/CFS
Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research
The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related…
- Conditions
- Post-Acute COVID-19 Syndrome, ME/CFS, Rheumatic Arthritis, Juvenile Rheumatoid Arthritis (JRA)
- Trial name
- NCT04806620
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Brain Inflammation Collaborative
Healthy
Influence of an Inspiratory Muscle Fatigue Protocol on Healthy Youngs on Respiratory Muscle Strength, Vertical Jump Performance and Muscle Oxygen Saturation
Respiratory muscle training represents an effective method increasingly utilized in both sports and healthcare domains, employing various devices, among which threshold devices are prominent.
- Trial name
- NCT06271876
- Testing
- Inspiratory muscle training
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Sierra Varona SL
Healthy
Electrical Stimulation With Different Currents and Electromagnetic Fields
Muscle strength is the amount of force generated by muscle contraction. It could be measured with an isometric dynamometer. This is a validated tool that could be used to measure Maximal Voluntary Isometric Contraction (MVIC) and…
- Trial name
- NCT05500300
- Testing
- Neo-Russian, Aussie, RBS
- Where
- Argentina
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maimonides University
Muscle Fatigue
Physiological Constraints Associated With Trail Running
The practice of mountain running or "trail" is in full development in France and elsewhere in the world. This sporting practice associates specific physiological constraints related in particular to the duration of the efforts…
- Trial name
- UT4M2018 (NCT03712592)
- Testing
- Pre and post running evaluations
- Where
- France
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Motor Activity
Electromyography During Common Exercises Used in Rehabilitation
It is generally accepted that the effectiveness of an exercise can be controlled not only by the weight or resistance applied but also by doing an exercise that would better target the desired muscle.
- Trial name
- NCT01400347
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University