Clinical trials: Muscle Loss
Sarcopenia, Arteriosclerosis
Effects of Lower Body EMS Training in Postmenopausal Women
This study evaluates the effects of a 8-week lower body Electrical Muscle Stimulation (EMS) training program on body composition, muscle function, and arteriosclerosis markers in postmenopausal women.
- Conditions
- Sarcopenia, Arteriosclerosis, Arterial Stiffness, Blood Pressure, Postmenopausal Women
- Trial name
- LB-EMS-PMW (NCT07385534)
- Testing
- Lower-body Electromyostimulation (LB-EMS) device, Lower Body Resistance Training
- Where
- South Korea
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Seoul National University
Sarcopenia
Middle Age muScle Krill Study
This study will determine the effect of 6 months of supplementation with krill oil on muscle strength and mass in middle-aged adults.
- Trial name
- MASK (NCT06005064)
- Testing
- Krill oil, Vegetable oil
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Healthy, Perimenopausal Depression
Multidimensional Determinants of Functional Health In Women Aged 45-60
The goal of this observational study is to learn about the multidimensional determinants of functional health in women aged 45 to 60 years.
- Conditions
- Healthy, Perimenopausal Depression, Menopausal Complaints, Bone Mineral Density
- Trial name
- NCT07667699
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kartal City Hospital
Muscle Protein Synthesis, Sarcopenia
The Impact of a Whole-food Animal-based Versus Plant-based Protein Rich Meal on Muscle Protein Synthesis
Rationale: Food intake stimulates muscle protein synthesis rates. The magnitude of the anabolic response to feeding forms a key factor in regulating muscle mass maintenance.
- Trial name
- MeaL (NCT05151887)
- Testing
- Muscle protein synthesis
- Where
- Netherlands
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Sarcopenia
Effect of Nutrition Supplementation Combined With Resistance Exercise in Elderly With Sarcopenia.
The purpose of this study was determine whether milk or soy milk supplements combined with resistance exercise improved sarcopenia in the elderly.
- Trial name
- NCT05035121
- Testing
- milk supplement, soy milk supplement, resistance exercise
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Sarcopenia
Managing the Nutritional Needs of Older Filipino With Due Attention to Protein Nutrition and Functional Health Study
The study aims to determine the effect of protein nutrition and exercise on the body composition and functional capacity of Filipino older adults.
- Trial name
- ManoPo (NCT05953116)
- Testing
- Nutrition supplementation, Exercise
- Where
- Philippines
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Food and Nutrition Research Institute, Philippines
Ambulatory Geriatric Outpatients at High Risk of Frailty
Impact of Chronic Disease Control and Aging Psychology on Outcomes of Frailty-Sarcopenia Syndrome in Ambulatory Geriatric Patients
Pursuant to our previous longitudinal study (ClinicalTrials.gov ID: NCT02073370) in geriatric outpatients cooperated with the Department of Family Medicine, Department of Geriatrics and Gerontology, National Taiwan University…
- Trial name
- NCT02160093
- Where
- Taiwan
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Frailty, Surgery
Retrospective Analysis of Sarcopenia in Older Patients Undergoing Laparotomy
Assess the influence of sarcopenia on outcomes of emergency laparotomy in the over 65 age group
- Conditions
- Frailty, Surgery, Emergencies
- Trial name
- NCT04493710
- Testing
- Sarcopenia estimation
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Wirral University Teaching Hospital NHS Trust
Sarcopenia, Back Pain
The "Free From Pain Exercise Book" Versus "The Back Book".
This pragmatic randomised control feasibility trial aims to investigate the effectiveness of the "Free From Pain Exercise Book" in comparison to "The Back Book" for reducing back pain in adults aged 60 and over.
- Conditions
- Sarcopenia, Back Pain, Arthritis
- Trial name
- NCT05359107
- Testing
- "The Free From Pain Exercise Book", "The Back Book"
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Talita Cumi Ltd.
Cardiovascular Diseases, Osteoporosis
Guangzhou Nutrition and Health Study (GNHS)
Purpose: The Guangzhou Nutrition and Health Study (GNHS) project aims to assess the determinants of metabolic disease in nutritional aspects, as well as other environmental and genetic factors, and explore possible mechanisms…
- Conditions
- Cardiovascular Diseases, Osteoporosis, Diabetes Mellitus, Type 2, Metabolic Syndrome
- Trial name
- GNHS (NCT03179657)
- Volunteers
- 5,118 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Spinal Muscular Atrophy
A Drug-drug Interaction Study With Risdiplam Multiple Dose and Midazolam in Healthy Participants
This will be a Phase I, 2-part, open-label, non-randomized study to investigate the safety, tolerability, and pharmacokinetics (PK) of a multiple-dosing regimen of risdiplam (Part 1) and the effect of risdiplam on the PK of…
- Trial name
- NCT03988907
- Testing
- Risdiplam, Midazolam
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Sarcopenia
Detection and Treatment of Sarcopenia and Myosteatosis in Older African Americans
The objectives of this study are to: 1) validate a rapid, portable, cost-effective method for screening myosteatosis and sarcopenia using diagnostic ultrasound, and 2) investigate a novel approach to progressive resistance…
- Trial name
- ARMS-II (NCT02350465)
- Testing
- Eccentric Exercise, Concentric Exercise
- Where
- 3 sites in United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Sarcopenia
A Study of the Intervention Effect of a Hybrid Exercise Program on Elderly With Sarcopenia
Sarcopenia is a geriatric condition characterized by a progressive decrease in skeletal muscle content and loss of muscle function.
- Trial name
- NCT05694117
- Testing
- self-determine sequence exercise program, resistance training, Taichi exercise and resistance training
- Where
- China
- Volunteers
- 392 people, healthy volunteers welcome
- Sponsor
- Northeast Normal University
Cognition Disorders in Old Age, Cognitive Function
Impact of Nutrition, Sleep, and Physical Activity on Intellectual Function and Muscle Mass in Older Adults
The goal of this prospective, single site, interventional randomized control trial is to treat age related health conditions in adults older than 65 years and functional independence.
- Conditions
- Cognition Disorders in Old Age, Cognitive Function, Frailty/Sarcopenia, MCI
- Trial name
- INSPIOR (NCT06135740)
- Testing
- Fitbit wearing, with notification for sleep, activity and nutrition based fitbit data, Routine care
- Where
- Japan
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- Tokyo University
Sarcopenia
Milk and Milk-produce to Counteract the Loss of Muscle Mass and Function in Exercising Older Adults.
This project evaluates the use of different types of proteins from various food sources after an exercise session, on muscle mass and physical capacity in aged sarcopenic men (who have low muscle mass).
- Trial name
- PRO (NCT01883674)
- Testing
- Resistance training
- Where
- Canada
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Amyotrophic Lateral Sclerosis, Primary Lateral Sclerosis
Answer ALS: Individualized Initiative for ALS Discovery
Creation of a large repository of induced pluripotent stem cells (iPSC), bio-fluid samples (blood and spinal fluid (optional)), and cell lines for ALS gene identification.
- Conditions
- Amyotrophic Lateral Sclerosis, Primary Lateral Sclerosis, Flail Arm ALS, Progressive Muscular Atrophy
- Trial name
- AnswerALS (NCT02574390)
- Where
- 8 sites in United States
- Volunteers
- 1,049 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Chronic Obstructive Pulmonary Disease
Substudy : Patients With an Acute Exacerbation of Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. Its prevalence is in progression and COPD is expected to become the fourth leading cause of death by 2030.
- Trial name
- EXA (NCT02282436)
- Testing
- No specific intervention for this study
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Laval University
Sarcopenia, Child Development
Determination of Reference Values for Handgrip Strength and Bioimpedance Values in Healthy Turkish Children
In this study, our aim is to determine the reference values for the handgrip force and bioimpedance values in healthy Turkish children.
- Trial name
- NCT06001931
- Testing
- handgrip force and bioimpedance values in healthy Turkish children.
- Where
- Turkey (Türkiye)
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Sport Nutrition, Probiotic
Supplementation With GKEX Sports Probiotic Combo for Muscle Gain and Fat Loss Assessment
Objective: To discuss the "GKEX Sports Probiotics Combination (hereinafter referred to as GKEX)", a product commissioned by Grape King Biotechnology Co., Ltd., and its effects on increasing muscle mass, muscle strength, physical…
- Trial name
- NCT05909475
- Testing
- GKEX
- Where
- Taiwan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- National Taiwan Sport University
Sarcopenia
Combined Exercise and Nutrition Intervention for Spinal Sarcopenia
Sarcopenia in the lumbar paraspinal muscles is receiving renewed attention as a cause of spinal degeneration. However, there were few studies on the precise concept and diagnostic criteria for spinal sarcopenia.
- Trial name
- NCT04810312
- Testing
- Combined exercise and nutrition intervention
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital