Clinical trials: Muscle Loss
Sarcopenia
Assessing the Impact of "Super-whey" vs. Isonitrogenous Whey on Muscle Protein Synthesis
Skeletal muscle accounts for approximately 45-55% of total body mass in healthy adults and plays a pivotal role in whole-body metabolic health, locomotion and physical independence.
- Trial name
- ARLA-WHEY (NCT05701202)
- Testing
- Super-Whey protein, Isonitrogenous whey protein
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Muscle Atrophy
n3 PUFA and Muscle-disuse Atrophy in Young Women
This study will examine the influence of n3 PUFA supplementation on the rate of muscle atrophy in women undergoing 2 weeks of unilateral limb immobilization.
- Trial name
- NCT03059836
- Testing
- n3 PUFA-enriched fish oil
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- McMaster University
Sarcopenia
Insulin and Sarcopenia in the Elderly
Muscle loss with aging is a significant contributor to disability in older people. Our general hypothesis is that loss of muscle with aging, known as sarcopenia, may be due to inability of muscle to grow in response to insulin.
- Trial name
- NCT00690534
- Testing
- Insulin Regular, L-NMMA, Sodium Nitroprusside
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Sarcopenia, Cirrhosis, Liver
Impact of Dietary Assessment and Intervention on Outcomes in Liver Cirrhosis Patients
Malnutrition and reduced muscle mass have been associated with poor outcomes in many disease conditions including severe inflammatory bowel disease, liver failure and cancers.
- Trial name
- NCT05259930
- Testing
- Amino MP9
- Where
- Ireland
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons, Ireland
Sarcopenia, Respiratory Function Impaired
Respiratory Sarcopenia in Institutionalized Older Adults in the Region of Murcia
Objectives: The objectives of this study are to describe the prevalence of respiratory sarcopenia in institutionalized older adults.
- Trial name
- NCT06130800
- Where
- Spain
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Felipe León Morillas
Frailty
Effects of the Combined Intervention of Exercise, Fruit, and Vitamin Supplementation on Frailty in Older Adults
The goal of this cohort-based cluster-randomized controlled trial is to investigate the effect of the combined intervention of exercise, fruit, and vitamin supplementation on frailty among older adults.
- Trial name
- EFVF (NCT06225271)
- Testing
- the combined intervention of exercise, fruit, and vitamin supplementation
- Where
- China
- Volunteers
- 934 people, healthy volunteers welcome
- Sponsor
- Nanjing Medical University
Overweight and Obesity, Weight Loss
Exercise Training and Time-restricted Feeding in Overweight and Obese Adults
Overweight and obesity prevalence in adolescents and adults continues to remain significantly high in the United States. While diet and exercise improve many consequences of obesity, dietary strategies are not always nutrient…
- Trial name
- NCT03823872
- Testing
- Time restricted feeding, Normal feeding
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Kyle Hackney
Sarcopenia
Electrical Stimulation of Human Myocytes in Microgravity
The purpose of this study is to evaluate the changes of muscle, in microgravity. Which will help explain the health benefits of exercise.
- Trial name
- microG (NCT03665051)
- Testing
- Muscle Tissue Biopsy, Maximal Oxygen Consumption (V02max)
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Frailty, Sarcopenia
FrAilty Care and wEll-funcTion in Community Dwelling Older Adults
This study is looking at whether older people could benefit from an online monitoring platform to support their individual ambitions to maintain or improve functional ability.
- Conditions
- Frailty, Sarcopenia, Aging
- Trial name
- FACET (NCT03707145)
- Testing
- Consultation, Online Support, Empowered
- Where
- United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Aberystwyth University
Muscle Protein Synthesis, Sarcopenia
The Anabolic Properties of Fortified Plant-based Protein in Older People
Rationale: Consumption of sufficient dietary protein is fundamental to skeletal muscle mass maintenance and overall health. Conventional animal-based protein sources such as meat, poultry, fish, eggs, and dairy are considered…
- Trial name
- Strongplant (NCT05711095)
- Testing
- Fortified plant-based protein blend, Plant-based protein blend, Whey protein
- Where
- Netherlands
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Sarcopenia
Effect of HINEX Jelly on Nutritional Status in People With Possible Sarcopenia or Sarcopenia
HINEX Jelly is a jelly high protein supplement. This report is to investigate whether jelly high protein supplement can achieve greater muscle mass, muscle strength, physical performance and nutritional status in sarcopenia or…
- Trial name
- NCT05926375
- Testing
- HINEX Jelly ( jelly high protein supplement)
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Muscle Atrophy
Effectiveness of Egg Versus Whey Protein Powder During Resistance Training
Consumption of whole eggs has recently been shown to stimulate muscle protein synthesis to a greater degree than consumption of egg whites after a resistance training session.
- Trial name
- NCT05206253
- Testing
- Whole egg powder, Whey protein powder
- Where
- 2 sites in Canada
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Sarcopenia
Skeletal Muscle Apoptosis and Physical Performance; Oxidative RNA/DNA Damage and Repair in Aged Human Muscle
The age-related loss of muscle mass and strength, also termed sarcopenia, is a commonly recognized consequence of aging and has been associated with frailty, functional loss, hospitalization, and increased mortality among older…
- Trial name
- NCT01644279
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Florida
Androgen Receptor Abnormal, Endometrial Disorder
The Effect of Androgen Receptor Polymorphism on Endometrial Cancer
Endometrial tissue is a hormonal-dependent tissue in both pre- and postmenopausal period. The endometrial cells are expressing receptors for all sex hormones, mainly for estrogen, progesterone and androgens.
- Trial name
- AREC (NCT05157373)
- Testing
- Endometrial sampling and Peripheral blood collection, FSFI Scale
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Nicosia
Androgen Insensitivity Syndrome, Metabolic Parameters in AIS, CAIS, PAIS and MAIS
Androgen Receptor, Implications for Health and Wellbeing: Natural History Study of Individuals With Androgen Insensitivity
Background: Androgen effects in humans are usually (but not always) mediated by the androgen receptor which is coded for by the androgen receptor gene (AR gene).
- Conditions
- Androgen Insensitivity Syndrome, Metabolic Parameters in AIS, CAIS, PAIS and MAIS, Tumor Formation in AIS, CAIS, PAIS and MAIS, Sexual Function AIS, CAIS, PAIS and MAIS
- Trial name
- NCT04708431
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Respiratory Function Loss, Sarcopenia
Prototype of Innovative Food Product to Improve Respiratory and Peripheral Muscle Function in Humans
HIC1® compound has a presence in the form of a gel, which facilitates its oral intake (direct or diluted with water) and also administration through gastrostomy tubes or nasogastric tubes. All received a dose of 30 grams of gel.
- Trial name
- HIC1 (NCT06248437)
- Testing
- innovative nutraceutical-type food product that we designed called HIC1® from coffee mucilage
- Where
- Colombia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fundación Cardiovascular de Colombia
Obesity, Sarcopenia
Prevalence of Osteosarcopenic Obesity in Older Adults
Osteosarcopenic Obesity (OSO) is a syndrome characterized by the loss of bone and muscle in addition to increase in the fat tissue as a result of aging process.
- Conditions
- Obesity, Sarcopenia, Osteopenia, Osteoporosis
- Trial name
- NCT04288401
- Where
- Turkey (Türkiye)
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Sarcopenia
The Krill Ageing Muscle Mechanisms (KAMM) Study
This study aims to determine the mechanisms via which krill oil supplementation increases muscle strength and whether this translates to improvements in gait and functional characteristics in older adults.
- Trial name
- KAMM (NCT06296875)
- Testing
- Vegetable oil, Krill oil
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Non-sarcopenic Subjects, Possible Sarcopenia
Research on the Possible Relationship Between Sarcopenia and Oral Muscle Function
This study will focus on community-dwelling elderly individuals and will follow the community screening process recommended by AWGS.
- Conditions
- Non-sarcopenic Subjects, Possible Sarcopenia, Sarcopenia (With Low ASM by BIM)
- Trial name
- GSOM (NCT07658612)
- Testing
- Non interventional study
- Where
- Taiwan
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Chang Gung University of Science and Technology
Sarcopenia, Frailty at Older Adults
Targeting Sarcopenia and Frailty: Multicomponent Exercise With Focal Muscle Vibration
This study aimed to evaluate the efficacy of multicomponent exercises (aerobic exercises, strength exercises, and balance exercises), individualized with the application of a focal muscle vibration machine at the lower…
- Conditions
- Sarcopenia, Frailty at Older Adults, Cognitive Impairment, Adherence
- Trial name
- NCT07049809
- Testing
- Focal Muscle Vibration, Multicomponent Exercise
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya