Clinical trials: Muscle Protein Synthesis, open to volunteers
Muscle Protein Synthetic Response to Protein, Muscle Protein Synthesis
Diet Synergy in Muscle Protein Synthesis
In the present semi-crossover randomized design, 15 recreationally active young adults (19-40 y) will receive stable isotope tracer infusions and perform a single bout of resistance exercise.
- Conditions
- Muscle Protein Synthetic Response to Protein, Muscle Protein Synthesis, Muscle Health, Protein Metabolism
- Trial name
- POTATO (NCT07367854)
- Testing
- Resistance Exercise, Potato and Beef, Bread and Beef
- Where
- 2 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Motor Disorder, Reliability and Validity
Turkish Translation , Validity and Reliability of the Hypertonia Assessment Tool in Children With Motor Disorders
Translating batteries with good psychometric properties into Turkish will increase the number of assessment batteries we can use in our language for clinical and academic studies.
- Conditions
- Motor Disorder, Reliability and Validity, Hypertonia
- Trial name
- NCT07267442
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Kastamonu University
Cirrhosis
Novel Tracer Methods to Evaluate Muscle Protein Metabolism in Cirrhosis
To determine the rate and mechanisms of skeletal muscle protein synthesis and breakdown in cirrhotic patients by using multiple tracers and single muscle biopsies.
- Trial name
- NCT03225677
- Testing
- blood draw and muscle biopsy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The Cleveland Clinic
No Condition, Healthy Individuals
Protein Intake Distribution to Support Muscle Anabolism in Healthy Young Adults
The purpose of the study is to evaluate whether the distribution pattern of daily protein intake affects how much muscle protein can be built in the muscle after resistance exercise and at rest.
- Trial name
- NCT07245199
- Testing
- protein intake
- Where
- Netherlands
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Muscle Protein Synthesis
Re-evaluation of the Muscle-full Effect During Continuously Elevated Amino Acid Availability in Healthy Young Males
Muscle tissue consists of proteins. These proteins are built up of a collection of smaller building blocks: amino acids. When protein is consumed, it gets digested and absorbed into the blood.
- Trial name
- Muscle-full (NCT06721026)
- Testing
- Continuous intravenous stable isotope amino acid tracer infusion, Amino acid infusion
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Muscle Protein Synthetic Response to Protein
Nutritional and Physical Intervention During Bed Rest
Hospitalization often involves long periods of bed rest and reduced nutritional intake, which can lead to skeletal muscle loss and anabolic resistance.
- Trial name
- Bed-Plant (NCT07280819)
- Testing
- Nutritionally complete tube feed providing a sole source of nutrition with a plant-dominant protein mix, Nutritionally complete tube feed providing a sole source of nutrition with an animal-based protein mix, Neuromuscular Electrical Stimulation (NMES)
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Cancer of Prostate
The Impact of Physical Activity Versus Dietary Energy Restriction on Tumour and Muscle Protein Synthesis in Prostate Cancer Patients
Background: Prostate cancer is the second most common cancer and the fifth leading cause of death in men worldwide. Tumour growth is attributed to disproportionately greater protein synthesis rates relative to protein breakdown…
- Trial name
- DIRECT (NCT06406803)
- Testing
- Dietary energy restriction, Daily exercise
- Where
- Belgium
- Volunteers
- 45 people
- Sponsor
- Maastricht University Medical Center
Muscular Atrophy, Insulin Resistance
Human Skeletal Muscle Response to 5 Days of Bedrest in Young Adults
The goal of this intervention trial is to characterize skeletal muscle atrophy in healthy, young adults during short term bedrest.
- Conditions
- Muscular Atrophy, Insulin Resistance, Muscle Protein Synthesis
- Trial name
- FABRIC (NCT07178353)
- Testing
- Bedrest
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Queen's University
Obesity & Overweight, Women
Effect Of Whole or Skimmed Milk Greek Yogurt on Integrated Muscle Protein Synthesis, Glucose Homeostasis, and Cognition in Post-Menopausal Women
The study will examine the impact of adding two servings per day of skimmed or whole milk Greek yogurt on integrated muscle protein synthesis (iMPS), blood sugar control, and cognition in post-menopausal women with overweight and…
- Conditions
- Obesity & Overweight, Women, Menopause
- Trial name
- NCT07705724
- Testing
- Skimmed vs Whole Milk Greek Yogurt
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Type 2 Diabetes Mellitus (T2DM), Sarcopenia
HMB Plus Vitamin D to Preserve Muscle in Older Adults Starting Semaglutide
This randomized, double-blind, placebo-controlled trial will evaluate whether daily calcium beta-hydroxy-beta-methylbutyrate (calcium-HMB) plus vitamin D3 preserves muscle mass, physical function, and resting metabolism in adults…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Sarcopenia, Obesity, Muscle Loss
- Trial name
- PRESERVE-HMB (NCT07760948)
- Testing
- Calcium-HMB Plus Vitamin D3
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Vanderbilt University Medical Center