Clinical trials: Muscular Hypertrophy
Muscle Hypertrophy, Healthy and Well-Trained Men and Women
Time-Restricted Eating and Muscle Hypertrophy
The purpose is to examine the effects of time-restricted eating (TRE; consuming all calories within an 8-hour period each day) vs.
- Trial name
- NCT04000750
- Testing
- Time Restricted Eating, Normal Feeding, Resistance Training
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- California State University, Fullerton
Mitochondria, Strength
BFR and Muscle Mitochondrial Oxidative Capacity
Blood flow restricted (BFR) exercise has been shown to improve skeletal muscle adaptations to resistance exercise. BFR uses blood pressure cuffs (i.e., tourniquets) to reduce skeletal muscle blood flow during resistance exercise.
- Conditions
- Mitochondria, Strength, Hypertrophy
- Trial name
- NCT03723226
- Testing
- Low Load Resistance Exercise, Low Load Resistance Exercise + BFR
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Louisiana State University and A&M College
Aging
Metformin to Augment Strength Training Effective Response in Seniors (MASTERS)
The purpose of this study is to determine whether a commonly prescribed drug, metformin, can enhance the benefits seen during resistance exercise such as increased muscle mass and strength.
- Trial name
- NCT02308228
- Testing
- Progressive Resistance Training, Metformin
- Where
- 2 sites in United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Philip Kern
Hypertrophy, Muscle Strength
Reliability and Performance Analysis of the Use of Tissue Flossing for Blood Flow Restriction.
Blood flow restriction (RFS) is a widely studied technique that combines low-intensity exercise with vascular occlusion, resulting in muscular benefits.
- Trial name
- NCT06075901
- Testing
- Tissue Flossing, Blood Flow Restriction Cuff, Training Protocol
- Where
- Brazil
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Paulista University
Hypertrophy, Muscle Strength
Effect of Low-load Resistance Training vs. High-intensity Interval Training on Local Muscle Endurance
Local muscle endurance (LME) is the ability of a muscle(s) to resist fatigue and is needed for daily activities of life such as climbing stairs, lifting/moving objects, and in sport contexts like rock climbing, mixed martial…
- Conditions
- Hypertrophy, Muscle Strength, High-Intensity Interval Training, Resistance Training
- Trial name
- LLSIT (NCT05945641)
- Testing
- Low Load Resistance training, Sprint/High Intensity Interval Training
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Delayed Onset Muscle Soreness
The Effect of Low-Intensity Resistance Exercise Training
It was to compare the effect of low-load resistance training with blood flow restriction (LL-BFR) and high-intensity resistance training (HI-RT) on muscle strength, endurance and volume, functional performance, and delayed onset…
- Trial name
- NCT04755608
- Testing
- Low Intensity Exercises with Blood Flow Restriction, High Intensity Resistant Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Inherited Cardiac Arrythmias, Long QT Syndrome (LQTS)
Derivation of Human Induced Pluripotent Stem (iPS) Cells to Heritable Cardiac Arrhythmias
Human induced pluripotent stem cells (hiPSCs) have driven a paradigm shift in the modeling of human disease; the ability to reprogram patient-specific cells holds the promise of an enhanced understanding of disease mechanisms and…
- Conditions
- Inherited Cardiac Arrythmias, Long QT Syndrome (LQTS), Brugada Syndrome (BrS), Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)
- Trial name
- NCT02413450
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Skeletal Muscle
Leucine or Protein Supplementation and Resistance Training
The purpose of this study was to determine the effects of L-leucine (LEU) or different protein supplements standardized to LEU (~3.0 g/serving) on changes in body composition, strength, and histological attributes in skeletal…
- Trial name
- MPS (NCT03501628)
- Testing
- L-leucine + maltodextrin, Whey protein concentrate, Hydrolyzed whey protein concentrate
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Auburn University
Strength, Range of Motion
Low-Load Blood Flow Restriction Training vs Traditional Resistance Training Exercises Following ACLR Surgery
The main objective/s of the study is to compare the effectiveness of low load blood flow restriction training (LL-BFR) with traditional resistance training exercises (T-RT) at improving skeletal muscle hypertrophy, strength…
- Conditions
- Strength, Range of Motion, Pain-Knee, Skeletal Muscle Hypertrophy
- Trial name
- NCT06480032
- Testing
- Blood Flow Restriction band
- Where
- Pakistan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Abasyn University Peshawar
Exercise, Resistance Training
Muscle Response to High Intensity Interval Resistance Training (HIIRT)
Resistance training (RT) is one of the most important stimuli for muscle hypertrophy and it plays an important role on weight loss and fatty acid oxidation increase.
- Trial name
- HIIRT (NCT04321772)
- Testing
- High Intensity Interval Resistance Training, Traditional Resistance Training
- Where
- Italy
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Padova
Hypertrophy, Exercise Training
Resistance Training, Detraining, and Retraining Study 2024 (TraDeRe2024)
The goals of our research project are to identify factors explaining inter-individual variation in responses to resistance training (RT) and the baseline determinants underlying an individual's sensitivity to respond to RT.
- Conditions
- Hypertrophy, Exercise Training, Skeletal Muscle Atrophy, Healthy
- Trial name
- TraDeRe (NCT06573086)
- Testing
- Resistance Training
- Where
- Finland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Jyvaskyla
Hypertrophy
Neuromuscular Characteristics of Strict Vegetarians and Non-Vegetarians Women
A strict vegetarian diet includes only foods of plant-based origin and, despite being able to meet the nutritional needs of individuals of different ages, when correctly planned, it commonly offers a lower protein intake than a…
- Trial name
- NCT05576337
- Testing
- 16 weeks of strength training protocol
- Where
- Brazil
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Obesity, Overfeeding
Overeating Different Fats and Influence on Muscle Mass and Body Fat Accumulation
To investigate metabolic and molecular response to fatty acid-specific overfeeding in overweight subjects, in relation to changes in ectopic fat, lean tissue mass and insulin sensitivity
- Conditions
- Obesity, Overfeeding, Muscle Mass, Body Composition
- Trial name
- LIPOGAIN-2 (NCT02211612)
- Testing
- PUFA-group, SFA-group
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Skeletal Muscle Hypertrophy
The Effects of Heavier- and Lighter-load Resistance Training on Arm and Leg Muscle Mass in Young Adult Women
When you perform weightlifting, your body makes new proteins within your muscle. These new proteins can increase the size of the fibers within your muscle to make your muscle larger, a process called hypertrophy.
- Trial name
- FHALL (NCT04547972)
- Testing
- Higher-load resistance training, Lower-load resistance training
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Electric Stimulation Therapy, Muscle Strength
Effectiveness of NMES Associated to Vascular Occlusion in Functional Performance and Muscle Hypertrophy in Athlete's
This study evaluates the effect of training with neuromuscular electrical stimulation (NMES) associated with vascular occlusion of the lower limbs, for increased strength and hypertrophy of the quadriceps muscle of professional…
- Trial name
- NCT02406339
- Testing
- NMES, Vascular Occlusion
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Sarcopenia
Peanut Protein Supplementation to Augment Muscle Growth and Improve Markers of Muscle Quality and Health in Young Adults
This study will evaluate the adaptations in skeletal muscle that occur in response to 10 weeks of weight training with or without peanut protein supplementation in untrained men and women ages 18-30
- Trial name
- NCT04707963
- Testing
- Peanut protein powder, Full body resistance training
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Auburn University
Hypertrophy, Physiologic Hypertrophy
Beta2-adrenergic Agonism and Muscle Remodelling
The study aims to investigate gender-specific adaptations to beta2-adrenoceptor stimulation with selective short- and long-acting beta2-agonist with emphasis on skeletal muscle in relation to performance enhancing effects and…
- Conditions
- Hypertrophy, Physiologic Hypertrophy, Physical Activity
- Trial name
- NCT03565302
- Testing
- Formoterol, Terbutaline
- Where
- Denmark
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Morten Hostrup, PhD
Skeletal Muscle Physiology
Muscle Memory After Treatment With Anabolic Substance Clenbuterol and Resistance Training in Humans
The purpose of the project is investigate muscle memory and underlying mechanisms in humans following resistance training and use of the anabolic substance clenbuterol.
- Trial name
- NCT05692856
- Testing
- Clenbuterol
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Morten Hostrup, PhD
Menopause Related Conditions, Exercise Training
Effects of Estrogen on Muscle Gain During 12-weeks of Exercise in Post-menopausal Women
As females age and transition through menopause, the decline in oestrogen level profoundly affects skeletal muscle mass and function.
- Trial name
- HER-MUSCLE (NCT07617454)
- Testing
- Estrogel, Physical exercise
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mette Hansen
Healthy Adult, Athlete
Comparison Between Eccentric Hamstring Training and Sprint-Specific Training
The purpose of this study is to compare the effects of an intensity-, volume-, and time under tension-matched eccentric hamstring exercise intervention with the Romanian deadlift (RDL) and the Nordic hamstring exercise (NHE) to a…
- Conditions
- Healthy Adult, Athlete, Exercise Training, Sport
- Trial name
- NCT07716319
- Testing
- RDL, NHE, Sprint testing
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison