Clinical trials: Musculoskeletal
Disc Degenerative Disease, Spondylolisthesis
A Clinical Study of a Spine Fusion System in Vertebral Body Fusion Surgery
The primary objective of this study is to demonstrate that the efficacy and safety of Spine fusion system manufactured in China is no inferior than imported product.
- Conditions
- Disc Degenerative Disease, Spondylolisthesis, Spinal Fracture, Spinal Deformity
- Trial name
- NCT02252185
- Testing
- Johnson&Johnson Medical Suzhou made Spine Fusion System, Imported EXPEDIUM screws and OPAL cage
- Where
- 8 sites in China
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Medical (Suzhou) Ltd.
Rheumatoid Arthritis (RA)
Vitamin d Level and it's Association With Disease Activity in Egyptian Rheumatoid Arthritis Patients
Vitamin D level and its association with disease activity in Egyptian Rheumatoid arthritis (RA) patients
- Trial name
- Vitamind (NCT05486715)
- Testing
- Vit D
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Mariam Samir Farg
Rhabdomyolysis, Acute Kidney Injury
Use of a Vacuum Mattress During Laparoscopic Sleeve Gastrectomy to Reduce the Concentration of Rhabdomyolysis Markers and Acute Renal Failure
This prospective clinical trial aimed to assess the usefulness of the usage of a vacuum mattress during laparoscopic sleeve gastrectomy (LSG) in the reduction of levels of rhabdomyolysis markers (myoglobin, creatine kinase…
- Conditions
- Rhabdomyolysis, Acute Kidney Injury, Bariatric Surgery Candidate
- Trial name
- NCT06338423
- Testing
- vacuum mattress, Standard Mattress
- Where
- Poland
- Volunteers
- 1,184 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Bone Growth Abnormal, Inflammation
Effects of Increased Greek Yogurt Consumption in Youth and Young Adult Athletes
Physical activity and dairy consumption during growth and development are each known to improve peak bone mass in young adults. Peak bone mass, the maximum amount of bone a person will have in their lifetime, is typically reached…
- Trial name
- NCT05922462
- Testing
- Greek yogurt, Whey protein
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Brock University
Atrophy, Disuse, Insulin Resistance
Bedrest, Feeding Pattern, and Insulin Sensitivity
In the present study, the investigators will assess the impact of two different feeding patterns (continuous vs intermittent) on insulin sensitivity and muscle mass following bedrest.
- Trial name
- NCT02521025
- Testing
- Intermittent feeding pattern, Continuous feeding pattern
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Dyspareunia; Female
Physiotherapy Treatment With Capacitive Resistive Monopolar Radiofrecuency in Young Women With Dyspareunia
The hypothesis of this study is that capacitive-resistive monopolar radiofrecuency (CRMRF) with vaginal manual physiotherapy improves sexual health in young women suffering from dyspareunia (pain during sexual intercourse).
- Trial name
- [CRMRF] (NCT05844189)
- Testing
- Physical therapy modalities on pelvic floor (manual therapy), CRMRF
- Where
- Spain
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Escoles Universitaries Gimbernat
Osteopenia
A Study to Evaluate the Effect of Romosozumab (AMG 785) on Bone Quality of the Forearm in Postmenopausal Women With Low Bone Mass
The purpose of this study is to evaluate the effect of romosozumab on parameters of bone quality of the forearm using peripheral quantitative computed tomography (pQCT) following multiple subcutaneous dose administrations of…
- Trial name
- NCT00950950
- Testing
- Romosozumab
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Amgen
Vitamin D Status, Osteoporosis
Vitamin D Status and Bone Health of Older Adults in Care Facilities
Vitamin D deficiency is proposed to be prevalent in community-dwelling older adults, with prevalence substantially higher among older adults in residential care facilities.
- Conditions
- Vitamin D Status, Osteoporosis, Sarcopenia
- Trial name
- NCT04399291
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Ulster
TMJ Disorder
Effect of Order and Conjugation of Different Photobiomodulation Therapies and Anterior Repositioning Appliance in Management of TMD Cases
This study aimed to evaluate the effect of using Low level laser therapy / Infrared led therapy with anterior repositioning appliance in anterior dislocation patients with reduction (ADDwR) concerning: 1.
- Trial name
- NCT06103110
- Testing
- Photobiomodulation
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Gout
A Study to Evaluate ALN-XDH in Healthy Subjects and Patients With Gout
The purpose of this study is to: Part A: Evaluate the safety and tolerability of single ascending doses of ALN-XDH in healthy adult participants Part B: Evaluate the safety, tolerability and efficacy of ALN-XDH as monotherapy in…
- Trial name
- NCT05256810
- Testing
- ALN-XDH
- Where
- United Kingdom
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Alnylam Pharmaceuticals
Osteoporosis, Cardiovascular Diseases
Effect of Soy Bread on Markers of Bone Metabolism and Cardiovascular Disease
A study was designed with two specific aims: (1) to assess the effect of soy bread, compared with wheat bread, on markers of bone metabolism and cardiovascular health, and (2) to evaluate whether soy bread consumption affects the…
- Trial name
- NCT00366860
- Testing
- Soy bread
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Colles' Fracture
Low-level Laser Therapy in Distal Radius Fractures
Conservative treatment of distal radius fracture is immobilisation with cast for 4-6 weeks. After removing the cast, it is common to still have pain, swelling and reduced mobility in the wrist.
- Trial name
- NCT03014024
- Testing
- Low-Level Laser Therapy
- Where
- Norway
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Osteoporosis
Jogging in the Change of Osteoporosis
To test the changes in osteoarthritis according to the X-rays, and changes in bone quality before and 1 or more years after beginning the jogging
- Trial name
- NCT03359317
- Testing
- jogging
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Spinal Stenosis
Cerebrospinal Fluid Congestion in Spinal Stenosis Patients
The investigators hypothesized spinal stenosis symptom was provocation due to cerebrospinal fluid congestion.
- Trial name
- NCT01630382
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Alveolar Bone Loss
Biologically Oriented Alveolar Ridge Preservation (BARP) With and Without Advanced Platelet-Rich Fibrin Plus (A-PRF+)
Twenty patients were selected from the outpatient clinic of the Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Mansoura University seeking for extraction of non-restorable maxillary premolar teeth prior to…
- Trial name
- NCT07869082
- Testing
- Socket preservation by deproteinized bovine bone graft, socket preservation by deproteinized bovine bone graft mixed with advanced PRF+
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Osteoarthritis
Application of Injectable Platelet-Rich Fibrin for the Treatment of Temporomandibular Joint Osteoarthritis
The authors designed a randomized, controlled, double-blind clinical trial after the ethical approval by the University Ethics Committee.
- Trial name
- NCT04810923
- Testing
- i-PRF, Arthrocentesis
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ege University
Bone Resorption
Sinus Augmentation in the Posterior Maxillary Region: a Case Report of 0mm Bone Height.
Sinus floor elevation (SFA) and GBR have been applied in the placement of dental implants in longstanding edentate posterior maxilla region.
- Trial name
- NCT06063980
- Testing
- Conventional sinus lift surgery, Two-stage-sinus-lift procedure
- Where
- Vietnam
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- VNU University of Medicine and Pharmacy
Still's Disease, Adult-Onset
Assessment of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of APB-R3
This will be a single centre, Phase 1, First-In-Human, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Ascending Dose of APB-R3 in Healthy…
- Trial name
- NCT05715736
- Testing
- APB-R3
- Where
- Australia
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Syneos Health
Overweight, Physical Capacity
Physical Exercise, Dietary Counseling and Cognitive Behavioral Training as a Combined Intervention to Reduce Weight and Increase Workability in Health Care Workers
The purpose of this study is to evaluate whether a 1 year worksite based life-style intervention can reduce body weight and increase physical capacity and subsequently reduce musculoskeletal disorders and increase workability in…
- Conditions
- Overweight, Physical Capacity, Musculoskeletal Diseases, Work Ability
- Trial name
- FINALE-Health (NCT01015716)
- Testing
- Intervention-group, Control-group
- Where
- Denmark
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Axial Spondyloarthritis, Ankylosing Spondylitis
Osteosarcopenia in Axial Spondyloarthritis
Axial spondyloarthritis is a chronic inflammatory disease affecting the spine, sacroiliac joints, entheses, and sometimes peripheral joints with a close link to HLAB27.
- Conditions
- Axial Spondyloarthritis, Ankylosing Spondylitis, Axial Spondyloarthritis, Non-Radiographic, Osteoporosis
- Trial name
- NCT06577350
- Where
- Turkey (Türkiye)
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Ankara University
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