Clinical trials: Myocardial Ischemia
Bone Diseases, Breast Neoplasms
Women's Health Initiative (WHI)
To address cardiovascular disease, cancer, and osteoporosis, the most common causes of death, disability, and impaired quality of life in postmenopausal women.
- Conditions
- Bone Diseases, Breast Neoplasms, Cardiovascular Diseases, Colonic Neoplasms
- Trial name
- NCT00000611
- Testing
- hormone replacement therapy, estrogens, progestins
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Coronary Disease
Post Coronary Artery Bypass Graft (CABG) Study
To determine the relative effectiveness of moderate versus more aggressive lipid lowering, and of low dose anticoagulation versus placebo, in delaying saphenous vein coronary bypass graft atherosclerosis and preventing occlusion…
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Ischemia
- Trial name
- NCT00000463
- Testing
- lovastatin, cholestyramine, warfarin
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Coronary Disease
Lipid Research Clinics Coronary Primary Prevention Trial (CPPT)
To determine whether reduction of cholesterol by drug therapy significantly lowered the atherosclerotic coronary heart disease rate in a group of hypercholesterolemic but otherwise healthy men.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Ischemia
- Trial name
- NCT00000488
- Testing
- cholestyramine, diet, fat-restricted
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Coronary Disease
Enhancing Recovery in Coronary Heart Disease (ENRICHD) Patients
To evaluate the effect of psychosocial intervention on mortality and reinfarction in coronary heart disease patients at high psychosocial risk.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Depression, Heart Diseases
- Trial name
- NCT00000557
- Testing
- social support
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Coronary Disease
Magnesium in Coronaries (MAGIC)
To determine whether early intravenous magnesium treatment of patients with suspected acute myocardial infarction reduces mortality.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Infarction
- Trial name
- NCT00000610
- Testing
- magnesium
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Myocardial Ischemia
Cohort Study of Heart Rate Variability
To examine factors affecting heart rate variability (HRV) and the role of HRV in heart disease. Specifically, to examine the role of HRV: as a predictor of fatal and nonfatal ischemic heart disease over a six year follow-up of…
- Conditions
- Cardiovascular Diseases, Myocardial Ischemia, Carotid Stenosis, Hypertension
- Trial name
- NCT00005399
- Testing
- No interventions
- Volunteers
- 111,654 people
- Sponsor
- University of North Carolina, Chapel Hill
Myocardial Infarction, Stroke
The Brain Heart Interaction in Acute Stroke
Many studies have shown that acute cerebral dysfunction can impair cardiac function and autonomic control of blood pressure, heart rate and vascular tone, however, the size of the stroke is rarely reported.
- Trial name
- NCT02734082
- Where
- Switzerland
- Volunteers
- 204 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Ischemic Heart Disease, Cardiovascular Diseases
Acute Safety, Deliverability and Efficacy of the Medtronic Resolute Integrity™ Zotarolimus-Eluting Coronary Stent System in the Treatment of Suitable Patients According to Indication for Use (CHINA RESOLUTE INTEGRITY STUDY)
The purpose of this study is to conduct a prospective, multi-center, single arm, non-randomized evaluation of acute outcomes in Chinese subjects, including those eligible for percutaneous transluminal coronary angioplasty (PTCA)…
- Conditions
- Ischemic Heart Disease, Cardiovascular Diseases, Arteriosclerosis, Coronary Artery Disease
- Trial name
- NCT02452736
- Testing
- Resolute Integrity™ Zotarolimus-Eluting Coronary Stent System
- Where
- 2 sites in China
- Volunteers
- 205 people
- Sponsor
- Medtronic Vascular
Ischemic Heart Disease, Atherosclerosis
Graft Patency as a Predictor of Health-related Quality of Life.
The health-related quality of life questionnaire "EQ-5D" has been collected in connection with several interventional and observational studies where the no-touch vein harvesting technique in CABG has been used.
- Trial name
- NCT02547194
- Where
- Sweden
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Örebro County Council
Cardiovascular Diseases, Coronary Disease
Asymptomatic Cardiac Ischemia Pilot (ACIP) Study
To assess the feasibility of and test the methodology for a full-scale clinical trial of therapies for asymptomatic cardiac ischemia.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Ischemia
- Trial name
- NCT00000478
- Testing
- atenolol, nifedipine, diltiazem
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Coronary Disease
Aspirin-Myocardial Infarction Study (AMIS)
To determine whether the daily administration of 1 gm of aspirin to individuals with a documented myocardial infarction would result in a significant reduction in mortality over a three year period.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Infarction
- Trial name
- NCT00000491
- Testing
- aspirin
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Coronary Disease
Harvard Atherosclerosis Reversibility Project (HARP)
To determine by sequential coronary arteriography whether a lipid-lowering diet with and without lipid-lowering drugs could reverse coronary artery disease in normocholesterolemic patients.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Ischemia
- Trial name
- NCT00000461
- Testing
- pravastatin, niacin, cholestyramine
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Angina Pectoris, Cardiovascular Diseases
Thrombolysis in Myocardial Ischemia Trial (TIMI III)
The Thrombolysis in Myocardial Ischemia Trial (TIMI III) focused on unstable angina and non-Q-wave myocardial infarction. The trial was designed to determine by coronary arteriography the incidence of coronary thrombi in these…
- Conditions
- Angina Pectoris, Cardiovascular Diseases, Coronary Disease, Heart Diseases
- Trial name
- NCT00000472
- Testing
- tissue plasminogen activator, heparin
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Coronary Disease
Thrombolysis in Myocardial Infarction (TIMI)
In TIMI I, to assess the relative thrombolytic activity and side effects of intravenous recombinant tissue-type plasminogen activator (rt-PA) versus intravenous streptokinase in patients with acute myocardial infarction.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases, Myocardial Infarction
- Trial name
- NCT00000505
- Testing
- tissue plasminogen activator, angioplasty, transluminal, percutaneous coronary
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Coronary Arteriosclerosis
Estrogen Replacement and Atherosclerosis (ERA) in Older Women
To determine if estrogen replacement therapy, with or without low dose progesterone, slows progression or induces regression of coronary atherosclerosis in postmenopausal women.
- Conditions
- Cardiovascular Diseases, Coronary Arteriosclerosis, Coronary Disease, Heart Diseases
- Trial name
- NCT00000549
- Testing
- estrogen replacement therapy, hormone replacement therapy, estrogens
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Heart Diseases
National Heart, Lung, and Blood Institute Twin Study
To assess genetic effects on the variation of cardiovascular and pulmonary risk factors in a cohort of 514 pairs of white male veteran twins.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Lung Diseases, Hypertension
- Trial name
- NCT00005124
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Heart Diseases
Predictors of Perioperative Cardiac Morbidity
To determine the predictors of perioperative cardiac morbidity and mortality in patients at high risk who underwent major noncardiac surgery with general anesthesia.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Myocardial Ischemia, Myocardial Infarction
- Trial name
- NCT00005197
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Heart Diseases
Cardiovascular Disease Mortality in The NAS-NRC Twin Registry
To analyze cardiovascular disease mortality and total mortality in the NAS-NRC Twin Registry using a new methodology that allowed for censored observations of outcomes, environmental covariates, and unmeasured…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension, Diabetes Mellitus
- Trial name
- NCT00005266
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Chronic Ischemic Heart Disease, Heart Failure
Human Umbilical-Cord-Derived Mesenchymal Stem Cell Therapy in Ischemic Cardiomyopathy
Phase I-II Clinical Trial-Safety and efficacy of umbilical cord derived mesenchymal stem cells (UC-MSCs) in patients with chronic heart ischemia cohort and perspective study.
- Conditions
- Chronic Ischemic Heart Disease, Heart Failure, Angina
- Trial name
- UCMSC-Heart (NCT02439541)
- Testing
- UCMSC group
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Angina Pectoris, Ischemic Heart Disease
Heart Rate Variability (HRV) Testing Compared With Exercise Stress Test in Hospitalized Patients With Chest Pain
There are many patients hospitalized for chest pain, which don't have high risk features that require invasive coronary angiography, but are considered intermediate risk and for which ischemic heart disease can not be excluded.
- Trial name
- NCT02530021
- Testing
- Heart rate monitor
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Meir Medical Center