Clinical trials: Neoplasm, Experimental
Plasmodium Falciparum Malaria
Experimental Vaccine for Malaria in Adults in Mali
This study will determine the highest dose of an experimental vaccine called AMA1-C1 that can safely be given to adults exposed to malaria.
- Trial name
- NCT00343005
- Testing
- AMA1-C1, AMA1-C1/alhydrogel Malaria Vaccine
- Where
- Mali
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Lung Diseases, Lung Cancer, Protection Against
Phase II Trial to Modulate Intermediate Endpoint Biomarkers in Former and Current Smokers
The purpose of this study is to find out if an investigational combination drug called Lovaza (made with fish oils)+Curcumin C3 Complex (made from a root called curcumin) can help reduce the size of lung nodules.
- Trial name
- NCT03598309
- Testing
- Curcumin C3 complex®, Lovaza®
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Breast Cancer Awareness, Health Education
A Quasi-Experimental Study to Improve Breast Cancer Awareness Among University Students
Breast cancer is one of the most common cancers among women worldwide and a leading cause of cancer-related deaths. Despite advances in early detection and screening methods, breast cancer remains a significant public health…
- Conditions
- Breast Cancer Awareness, Health Education, Early Detection of Cancer
- Trial name
- BCAwarenessUni (NCT07118969)
- Testing
- Breast Cancer Awareness Training
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mardin Artuklu University
Pancreatic Neoplasm, Magnetic Resonance Imaging
MRE for Diagnosis of Pancreatic Masses
Pancreatic ductal adenocarcinoma (PDAC) accounts for 85-95% of pancreatic cancer and is one of the deadliest tumors in the world, with a survival rate of less than 8%, and identifying key prognostic or predictive factors…
- Trial name
- MREDPCM (NCT06526442)
- Testing
- magnetic resonance imaging
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yu Shi
Breast Cancer
Scripps Polster Breast Care Center Investigational GeneBank
Breast cancer is a disease of complex origin with a strong genetic component. The incidence of breast cancer is very high in monozygotic twins of patients, and it is thought that a high proportion and perhaps the majority of…
- Trial name
- PINK (NCT00945464)
- Testing
- Blood/saliva samples, historic breast imaging
- Where
- United States
- Volunteers
- 1,136 people, healthy volunteers welcome
- Sponsor
- Scripps Translational Science Institute
Healthy Volunteers
An Investigational Study to Assess the Effect of a Light Meal and a High-Fat Meal on the Absorption of BMS-986205 in Healthy Participants
The purpose of this study is to investigate the effect of a light meal and a high-fat meal on the bioavailability (absorption) of of BMS-986205 commercial tablet in healthy participants.
- Trial name
- NCT03312426
- Testing
- BMS-986205
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Effect of Health Education Regarding Screening Tools of Breast Cancer
Effect of Health Education on Female Teachers' Knowledge and Practices Regarding Early Breast Cancer Detection and Screening in the Jazan Area: A Quasi-Experimental Study
The purpose of this study is to assess the effectiveness of health education in improving the knowledge and practices of female teachers regarding screening tools and the early detection of breast cancer.
- Trial name
- NCT03398057
- Testing
- Health education, Control group
- Where
- Saudi Arabia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Anwar Ali Ahmad Alameer
Cancer, Nursing
The Effect of Hippotherapy on The Development of Life Satisfaction, Health Literacy and Healthism Attitude of Young Adults After Cancer Treatment
This research aims to evaluate the impact of hippotherapy on life satisfaction, health literacy, and health culture among young adults who have undergone cancer treatment.
- Conditions
- Cancer, Nursing, Hippotherapy, Life Satisfaction
- Trial name
- NCT06467331
- Testing
- Hippotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Betül Çakmak
Bereavement
Family Cancer Caregivers Receiving a Specific Supportive Care Intervention Pre- and Postloss
Background and study aims The effect of cancer caregiving may have profound impact on the psychosocial health of family caregivers and become evident after loss.
- Trial name
- FAM-SOTC-PL (NCT03850132)
- Testing
- FAM-SOTC-PL
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Iceland
Breast Cancer
Evaluating Image Quality and Comfort of an Investigational Curved Paddle Compared to a Standard Paddle
The goal of this study is to evaluate patient comfort during compression with a standard flat mammographic paddle and an investigational curved paddle.
- Trial name
- NCT03611543
- Testing
- Standard of Care Flat Paddle, Investigational Curved Paddle
- Where
- 4 sites in United States
- Volunteers
- 443 people, healthy volunteers welcome
- Sponsor
- Hologic, Inc.
Immune System
An Experimental Medicine Clinical Study to Compare Peripheral Immune System From Subjects Without Cancer Diagnosis and Patients With Solid Tumours.
The aim of the study is to gain knowledge concerning expression of immune markers on immune cell subpopulation of PBMCs from subjects without cancer diagnosis and cancer patients.
- Trial name
- IMMUNOPBMC (NCT05133128)
- Testing
- blood samples
- Where
- 2 sites in France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Servier
Head and Neck Squamous Cell Carcinoma
An Experimental Study to Compare Treatment Response and Toxicities of Concurrent Chemoradiation With Weekly Cisplatin and Three Weekly Cisplatin in Locally Advanced Head and Neck Cancer.
The aim of this study is to compare treatment responses and toxicities of concurrent chemo-radiation with weekly and three weekly Cisplatin in locally advanced Head \& Neck Cancer.
- Trial name
- HNC (NCT03998696)
- Testing
- Cisplatin 40 mg/m2, Cisplatin 100 mg/m2
- Where
- Bangladesh
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Pediatric Cancer, Pediatric Oncology
Central Venous Catheter Care Training for Pediatric Oncology Nurses
The knowledge level of nurses regarding care techniques plays a crucial role in the prevention of central venous catheter-related infections.
- Conditions
- Pediatric Cancer, Pediatric Oncology, Central Venous Catheter, Central Venous Catheter Placement
- Trial name
- NCT07345598
- Testing
- CVC Care Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fenerbahce University
Cervical Cancer, Human Papillomavirus Infection
Effect of Health Belief Model-Based Education on Cervical Cancer Knowledge and HPV Vaccine Attitudes in Women
This study evaluated the effect of a Health Belief Model-based educational intervention on women's knowledge of cervical cancer and their attitudes and beliefs toward HPV vaccination.
- Conditions
- Cervical Cancer, Human Papillomavirus Infection, Preventive Health Services
- Trial name
- HBM-HPV (NCT07521163)
- Testing
- Health Belief Model-Based Education
- Where
- Turkey (Türkiye)
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Muhammet Faruk Yigit
Evaluation of the Effects of Education Provided on Family Members Caring for Colorectal Cancer Patients
The Effect of Education Provided to Family Members Caring for Colorectal Cancer Patients on Caregiving Reactions and Healthy Lifestyle Behaviors: A Prospective Quasi-experimental Study.
The effect of education provided to family members caring for colorectal cancer patients on caregiving reactions and healthy lifestyle behaviors: A prospective quasi-experimental study
- Trial name
- NCT04791982
- Testing
- Educational sessions
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ankara University
Health Belief Model, Nursing Students
The Effect of Health Belief Model-Based HPV Infection and Vaccination Education on University Students' Knowledge and Health Beliefs
This study aimed to examine changes in knowledge and health beliefs (perceived susceptibility, severity, benefits, and barriers) regarding HPV infection and cervical cancer among students residing in a university dormitory…
- Conditions
- Health Belief Model, Nursing Students, HPV (Human Papillomavirus)-Associated
- Trial name
- NCT07900113
- Testing
- Educational intervention HPV
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Mersin University
Cervical Intraepithelial Neoplasia
A Study on the Immune Response and Safety of an Adjuvanted Human Papillomavirus Vaccine When Given to Healthy Women 16 to 26 Years of Age
The main purpose of this study was to evaluate the safety and reactogenicity of GlaxoSmithKline Biologicals SA (GSK)'s investigational adjuvanted human papillomavirus (HPV) vaccine formulations.
- Trial name
- NCT05496231
- Testing
- HPV9 High formulation, HPV9 Medium formulation, HPV9 Low formulation
- Where
- 68 sites in United States, Bulgaria and 6 more
- Volunteers
- 1,080 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Cancer Prevention, Health Behavior
Program of Health Behaviour Against to Cancer (PHeBAC)
The European Code Against Cancer contains 12 recommendations to reduce the risk of cancer. It is estimated that about half of all cancers could be prevented if all recommendations are followed.
- Conditions
- Cancer Prevention, Health Behavior, Disability, Intellectual, Parents
- Trial name
- PHeBAC (NCT06371469)
- Testing
- PHeBAC, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Healthy, Adolescents
Integration to Improve Adolescent Health and HPV Vaccination in Laos
The goal of this study is to find out if adding HPV vaccination to adolescent health services works to increase HPV vaccine uptake in 10-13-year-old girls in Laos.
- Conditions
- Healthy, Adolescents, Integrated, Community-Health Systems, HPV Vaccines
- Trial name
- NCT06650956
- Testing
- Integrated HPV and SRH Service Package, Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) Vaccine, Recombinant
- Where
- Laos
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Health Poverty Action
Chronic Disease, Cardiovascular Diseases
CEPPPIA Pilot. Experimental Center of Participative and Individualized Predictive Prevention in Auvergne
The state of health in France appears to be good with regard to major indicators such as life expectancy at birth. However, France is characterized by a high standardized rate of premature mortality (deaths occurring before the…
- Conditions
- Chronic Disease, Cardiovascular Diseases, Cancers, Diabetes Mellitus
- Trial name
- CEPPPIA (NCT03378895)
- Testing
- online questionnaire
- Where
- France
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand