Clinical trials: Nephrolithotomy
Urosepsis, Kidney Stone
Effect of Emergency Urinary Drainage on Subsequent PCNL Outcomes in Obstructive Urosepsis
Obstructive urolithiasis complicated by urosepsis is a life-threatening medical emergency requiring urgent urinary tract decompression.
- Trial name
- NCT07826325
- Testing
- Retrograde Ureteral Stenting followed by PCNL, Percutaneous Nephrostomy followed by PCNL
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Beni-Suef University
Pain, Acute Postoperative, Renal Stone
Continuous Erector Spinae Plane Blocks to Treat Pain Following Percutaneous Nephrolithotomy
This is a randomized, triple-masked, placebo-controlled parallel-arm human subjects clinical trial investigating the addition of a continuous erector spinae plane nerve block to a single-injection erector spinae plane block to…
- Trial name
- NCT05121168
- Testing
- Active bupivacaine 0.25% via an erector spinae plane perineural catheter
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of California, San Diego
Percutaneous Nephrolithotomy
Conventional PCNL Versus Tubeless PCNL
prospective randomized study measuring the safety and efficacy of tubeless PNL in patients at assiut university hospital comparing to the standard PNL
- Trial name
- NCT03907930
- Testing
- percutaneous nephrolithotripsy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Nephrolithiasis
The Application of Health Education Path Nursing Program
Objective: To explore the effect of health education pathway on self-management ability and quality of life of patients after percutaneous nephrolithotomy.
- Trial name
- NCT07047625
- Testing
- control group (Routine nursing), Experimental group （Health education path）
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Fuyang Affiliated Hospital of Anhui Medical University
Pediatric Renal Stones
Efficacy and Safety of Flexible Ureteroscopy With Flexible Navigable Suction Ureteral Access Sheath Versus Mini-Percutaneous Nephrolithotomy With Vacuum-Assisted Access Sheath
Mini-percutaneous nephrolithotomy (mini-PCNL) and retrograde intrarenal surgery (RIRS) are both effective treatment modalities for renal calculi measuring up to 2.5 cm in pediatric patients, demonstrating similar efficacy and…
- Trial name
- NCT07763743
- Testing
- Flexible Ureteroscopy
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Ain Shams University
Kidney Stones
Laser Versus Ultrasonic Lithotripsy in Percutaneous Nephrolithotomy for Staghorn Stones
This study will be conducted to compare the results of Laser and ultrasonic lithotripsy in disintegration of staghorn stones during percutaneous nephrolithotomy.
- Trial name
- NCT01922414
- Testing
- Laser, Ultrasonic
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Mansoura University
Nephrolithiasis
Outcomes and Inter-Stage Interval in Staged Bilateral PCNL
This prospective, single-center observational study evaluated patients undergoing staged bilateral standard percutaneous nephrolithotomy (PCNL) for bilateral renal stones.
- Trial name
- NCT07854743
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Ankara Training and Research Hospital
Percutaneous Nephrolithotomy (PCNL), Perioperative Analgesia
Anterior QLB for PCNL
Aim: In this study, we primarily aimed to determine the effect of anterior Quadratus Lumborum Block (QLB) on intraoperative and postoperative opioid consumption in patients undergoing percutaneous nephrolithotomy (PCNL) surgery…
- Conditions
- Percutaneous Nephrolithotomy (PCNL), Perioperative Analgesia, Quadratus Lumborum Block, Opioid Consumption
- Trial name
- NCT07487415
- Testing
- ANTERİOR QUADRATUS LUMBORUM BLOCK ( anterior QLB)
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Zonguldak Bulent Ecevit University
Nephrolithiasis, Urinary Tract Infection (UTI)
Endourology Disease Group Excellence (EDGE) Consortium: Antibiotics (Abx) for Percutaneous Nephrolithotomy (PCNL) Part 2
This study will be a multi-institutional randomized clinical trial of a short course of pre-operative antibiotic prophylaxis in addition to perioperative antibiotics prior to undergoing percutaneous nephrolithotomy.
- Conditions
- Nephrolithiasis, Urinary Tract Infection (UTI), Sepsis
- Trial name
- PNLABXPART2 (NCT02829060)
- Testing
- Nitrofurantoin 100 MG, 7d, Gentamicin, 5mg/kg, Ampicillin 2g
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- University of California, San Diego
Urinary Tract Infection Bacterial, Nephrolithiasis
Blood Parameters as a Predictor of Fever After Percutaneous Nephrolithotomy
To investigate the relationship between neutrophil count, lymphocyte count, neutrophil-to-lymphocyte count ratio (NLR), and postoperative fever in patients undergoing percutaneous nephrolithotomy (PNL).
- Trial name
- NCT03774940
- Testing
- peripheric blood count
- Where
- Turkey (Türkiye)
- Volunteers
- 519 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Pain
Peritubal Infiltration of Bupivacaine in PCNL
Patients may feel significant pain at the surgery site after they wake up from the surgery. Usually pain is managed in the ward by giving strong pain medication that may slow down your mobilization and recovery process.
- Trial name
- NCT02198027
- Testing
- Bupivacaine, Normal saline infiltration
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Indus Hospital and Health Network
Kidney Calculi, Nephrolithiasis
Metaphylaxis of Infected Kidney Stones After Percutaneous Nephrolithotripsy
Kidney stone recurrence, particularly infection-related stones, remains a significant clinical problem after percutaneous nephrolithotripsy (PCNL).
- Conditions
- Kidney Calculi, Nephrolithiasis, Urinary Tract Infections
- Trial name
- DIOX-PCNL (NCT07393711)
- Testing
- Dioxidine, Percutaneous Nephrolithotripsy (PCNL)
- Where
- Kazakhstan
- Volunteers
- 95 people
- Sponsor
- West Kazakhstan Marat Ospanov Medical University
Urolithiasis
Bacterial Analysis of Kidney Stones Removed by Percutaneous Nephrolithotomy
The aim of this research is to use a controlled laboratory setting to determine whether bacteria isolated from kidney stones of patients play a role in the formation of non-infectious kidney stones.
- Trial name
- NCT02739919
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- University of British Columbia
Artery Pseudoaneurysm After PCNL
Renal Artery Pseudoaneurysm After PCNL
In a multicenter retrospective study, to assess the incidence and risk factors of renal artery pseudoaneurysm after percutaneous nephrolithotomy, and to characterize the clinical presentation and treatment outcomes.
- Trial name
- NCT07724912
- Testing
- Embolization of a renal artery branch pseudoaneurysm
- Volunteers
- 50 people
- Sponsor
- Botkin Hospital
Kidney Stone
Ultrasound-guided Transmuscular Quadratus Lumborum Block for Percutaneous Nephrolithotomy
Patients undergoing percutaneous nephrolithotomy (PNL) suffer from acute postoperative pain, despite a multimodal analgesic regime.
- Trial name
- NCT02818140
- Testing
- Ropivacaine TQL block, Saline TQL block, Ropivacaine
- Volunteers
- 60 people
- Sponsor
- Zealand University Hospital
Nephrolithiasis, Anesthesia, Local
Over 2000 Epidural Anesthesias for Percutaneous Nephrolithotomy - a Retrospective Analysis
Percutaneous nephrolithotomy (PNL) is a renal lithiasis treatment. It is usually two staged: it begins in the lithotomy position for ureteral catheter placement and retrograde pyelography and, subsequently, an optimal renal…
- Trial name
- NCT02986997
- Where
- Poland
- Volunteers
- 2,000 people
- Sponsor
- Medical University of Warsaw
Nephrolithiasis
Intraoperative Cone-beam CT for Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy (PCNL) is a first-line treatment for kidney stones >2cm. Frequently, patients require multiple procedures to address their stone burden.
- Trial name
- NCT04556396
- Testing
- Cone beam CT
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- Loyola University
Extravascular Lung Water, Percutaneous Nephrolithotomy
Ultrasound Assessment of Extravascular Lung Water in Patients Undergoing Percutaneous Nephrolithotomy
Early detection of fluid accumulation in alveolar, interstitial and intracellular compartments of the lung due to intravascular absorption of irrigation fluid of PNL guided by lung ultrasound by detection of sonographic B lines.
- Trial name
- NCT06141746
- Testing
- Lung ultrasound
- Volunteers
- 100 people
- Sponsor
- Assiut University
Postoperative Pulmonary Complication, Mechanical Power
Postoperative Pulmonary Complications in Adult PNL Patients
The aim of this study is to investigate the effect of different surgical positions (supine/prone) on lung mechanical power (MP) and its relationship with postoperative pulmonary complications in patients planned to percutaneous…
- Trial name
- NCT06462976
- Testing
- mechanical power calculation
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- TC Erciyes University
Percutaneous Nephrolithotomy
The Minimal Effective Volume (MEV90) of Ropivacaine 0.75% for Ultrasound-guided Transmuscular Quadratus Lumborum Block
This double-blind dose-finding trial is based on a biased coin up-and-down sequential design, where the volume of local anesthetic administered to each patient depends on the response from the previous one.
- Trial name
- NCT04196270
- Testing
- Ropivacaine injection
- Volunteers
- 40 people
- Sponsor
- Zealand University Hospital