Clinical trials: Nerve Pain
Eye Pain, Neuropathy, Optic
Alternating and Direct Current Stimulation for Neuropathic Eye Pain
The goal of this clinical intervention is to test if two forms of transcranial current stimulation, transcranial direct current stimulation (tDCS) or transcranial alternating current stimulation (tACS) can alleviate neuropathic…
- Conditions
- Eye Pain, Neuropathy, Optic, Cerebral Injury
- Trial name
- NCT05931250
- Testing
- DC-Stimulator Plus (NeuroConn GmbH, Germany), Sooma direct current stimulator (Sooma, Finland)
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Neil Lagali
Analgesia, Pain, Acute
A Randomized Comparison Between 0.67 mcg/kg, 1 mcg/kg, and 1.33 mcg/kg of Perineural Dexmedetomidine for Ultrasound-Guided Infraclavicular Block
This study will compare three different doses of perineural dexmedetomidine 0.67 mcg/kg, 1 mcg/kg, and 1.33 mcg/kg as adjuvants to local anesthetics for ultrasound-guided infraclavicular brachial plexus blocks (ICBs).
- Conditions
- Analgesia, Pain, Acute, Upper Extremity Surgery, Nerve Block
- Trial name
- NCT07249827
- Testing
- dexmedetomidine (perineural) 0.67 mcg/kg, dexmedetomidine (perineural) 1 mcg/kg, dexmedetomidine (perineural) 1.33 mcg/kg
- Where
- Canada
- Volunteers
- 69 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Sciatic Nerve, Lower Extremity Pain
Effect of Sciatic Nerve Mobilization on Lower Extremity Pain Perception
This randomized controlled study aims to investigate the effect of sciatic nerve mobilization on pain perception in lower extremity peripheral nerves, specifically the tibial and common peroneal nerves.
- Trial name
- NCT07525895
- Testing
- Sciatic Nerve Mobilization
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Fenerbahce University
Paravertebral Block, Pectoral Nerve Block
Pectoral Nerve Block Versus Paravertebral Block In The Incidence of Chronic Pain After Breast Cancer Surgery
Chronic pain after Mastectomy is frequent and an important healthcare priority because of its effect on quality of life. Although the association between the severity of acute pain after surgery and the likelihood of chronic pain…
- Conditions
- Paravertebral Block, Pectoral Nerve Block, Chronic Pain, Mastectomy; Lymphedema
- Trial name
- NCT06082206
- Testing
- thoracic paravertebral block (TPVB), PECS group
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University
Rectal Surgery, Pain (Visceral, Somatic, or Neuropathic)
Post Operative Pain and Vagal Stimulation
Anorectal surgery is a type of surgery that can cause anal pain, particularly in the context of hemorrhoid surgery or anal fissure surgery. Generally, the period of discomfort related to the pain lasts about two weeks.
- Conditions
- Rectal Surgery, Pain (Visceral, Somatic, or Neuropathic), Vagal Nerve Stimulation
- Trial name
- VAGANAL (NCT07659314)
- Testing
- Experimental arm, Control arm
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Angers
Transcutaneous Electric Nerve Stimulation, Chronic Low-back Pain
High Frequency RF Current Effects on Muscle Pain and Function
The purpose of this study is to examine the acute and chronic effects of high frequency electrical current transfer (frequently called "TECAR") on pain and functional movement in individuals with a musculoskeletal injury or pain.
- Conditions
- Transcutaneous Electric Nerve Stimulation, Chronic Low-back Pain, Hamstring Injury, Muscle; Injury, Quadriceps (Thigh)
- Trial name
- NCT05345015
- Testing
- Radiofrequency Energy Transfer, Transcutaneous Nerve Stimulation
- Where
- 2 sites in Greece
- Volunteers
- 200 people
- Sponsor
- Aristotle University Of Thessaloniki
Quadro-Iliac Plane Block, Pericapsular Nerve Group Block (PENG Block)
PENG+LFCN Block vs QIPB for Total Hip Arthroplasty
This randomized clinical trial aims to evaluate and compare the analgesic efficacy and functional outcomes of the quadro-iliac plane block (QIPB) and the pericapsular nerve group (PENG) block combined with lateral femoral…
- Conditions
- Quadro-Iliac Plane Block, Pericapsular Nerve Group Block (PENG Block), Hip Arthroplasty, Total, Pain Management
- Trial name
- NCT07667231
- Testing
- Quadro iliac Plane Block(QİPB), PENG Block and LFCN Blok, Lateral femoral cutaneous nerve block(LFCN)
- Volunteers
- 60 people
- Sponsor
- Antalya City Hospital
Dental Anxiety, Inferior Alveolar Nerve
Reducing Pain During Dental Nerve Block Injections in Children
Title of Study: Effect of External Cooling and Vibration, Counterstimulation, and Needle Type on Pain, Physiological, and Behavioral Outcomes During Inferior Alveolar Nerve Block in Pediatric Patients Why was this study done? The…
- Conditions
- Dental Anxiety, Inferior Alveolar Nerve, Pain Management
- Trial name
- IANB (NCT07667725)
- Testing
- Buzzy Device, Counterstimulation, 30-Gauge Needle
- Where
- Iraq
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Pericapsuler Nerve Group Block, Postoperative Pain
The Effect of Pericapsular Nerve Group Block With Different Local Anesthetic Volumes
Early postoperative pain following shoulder surgery is a significant clinical problem for both patients and orthopedic surgeons. Effective pain control is crucial for improving postoperative comfort and optimizing rehabilitation.
- Trial name
- NCT07666737
- Testing
- pericapsular nerve group (PENG) block
- Volunteers
- 60 people
- Sponsor
- Selcuk University
Neuropathic Pain
Safety, Tolerability, and Pharmacokinetics of ASCT-83 in Healthy Adults
The goal of this clinical trial is to learn if ASCT-83 is safe and well-tolerated and measure how ASCT-83 is absorbed, distributed, and eliminated from the body over time. The study will be conducted in healthy adults.
- Trial name
- NCT07363395
- Testing
- ASCT-83
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Alcamena Stem Cell Therapeutics
Lumbar Degenerative Disease, Lumbar Radiculopathy
Comparison of Clinical Effectiveness of Full Endoscopic Lumbar Discectomy (FELD) and Microdiscectomy (MD) in Patients With Lumbar Disc Herniation
The goal of this clinical trial is to compare the clinical effectiveness of Full Endoscopic Lumbar Discectomy (FELD) and Microdiscectomy (MD) in patients aged 18-85 with single-level lumbar disc herniation who have not undergone…
- Conditions
- Lumbar Degenerative Disease, Lumbar Radiculopathy, Sciatic Leg Pain, Sciatic Nerve Compression
- Trial name
- NCT06615518
- Testing
- FELD (Full-Endoscopic Lumbar Discectomy), comprising IELD and TELD as anatomical subgroups, Microdiscectomy
- Where
- 2 sites in Poland
- Volunteers
- 200 people
- Sponsor
- University of Opole
Symptomatic Neuroma, Amputation
Tolerability and Feasibility Pilot Clinical Study of a Large-Diameter Nerve Cap for Protecting and Preserving Terminated Nerve Ends
This pilot study evaluates the tolerability and feasibility of the Axoguard Large-Diameter Nerve Cap (sizes 5-7 mm) for protecting and preserving terminated nerve endings after limb trauma or amputation when immediate attention…
- Conditions
- Symptomatic Neuroma, Amputation, Chronic Nerve Pain
- Trial name
- REPOSE-XL℠ (NCT04865679)
- Testing
- Axoguard Nerve Cap®
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Axogen Corporation
Peripheral Nerve Block, Pain Management
Comparison of Postoperative Analgesic Effects of Quadro-iliac Plane Block and Transversus Abdominis Plane Blocks in Inguinal Hernia Surgery
Inguinal hernia repair is one of the most commonly performed surgical procedures worldwide. Despite being classified as a minor surgical intervention, moderate to severe postoperative pain is reported in approximately 60% of…
- Conditions
- Peripheral Nerve Block, Pain Management, Hernia, Inguinal
- Trial name
- NCT07442188
- Testing
- TAPB, QIPB
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Meniscopathy Surgery, Peripheral Nerve Block
Comparison of Analgesic Effects of ACB Versus ACB Combined With BiFeS Block in Meniscopathy Surgery
Meniscopathy surgeries are commonly associated with moderate postoperative pain, particularly during early mobilization and rehabilitation.
- Conditions
- Meniscopathy Surgery, Peripheral Nerve Block, Pain Management
- Trial name
- NCT07603323
- Testing
- Adductor Canal Block Group, Adductor Canal Block + BiFeS (Biceps Femoris Short Head) Block Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Ankara Etlik City Hospital
Nerve Injury, Pain Management
Study of Nerve Injuries and Physical Exercise
This study will explore if combining exercise with sensory training can help improve sensory function and reduce pain after an injury to the nerves in the arm and hand.
- Conditions
- Nerve Injury, Pain Management, Sensorial Disturbance
- Trial name
- SNIPE (NCT06846788)
- Testing
- Physical exercise
- Where
- Sweden
- Volunteers
- 7 people
- Sponsor
- Karolinska Institutet
Chronic Shoulder Pain, Pericapsular Nerve Group Block (PENG Block)
Ultrasound-Guided PENG Block for Chronic Shoulder Pain
The purpose of this prospective, observational study is to evaluate the clinical and functional outcomes of ultrasound-guided Pericapsular Nerve Group (PENG) block in patients suffering from chronic shoulder pain.
- Conditions
- Chronic Shoulder Pain, Pericapsular Nerve Group Block (PENG Block), Frozen Shoulder, Bursitis
- Trial name
- NCT07607691
- Testing
- Lidocaine and Dexamethasone for PENG Block
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Ankara City Hospital Bilkent
Magnesium Sulfate, Local Anesthetic
Adding Magnesium Sulfate to Local Anesthetic in Combined Pectoral Nerve and Stellate Ganglion Block for Postoperative Pain Control After Modified Radical Mastectomy
We aim to study the effect of adding magnesium sulfate as an adjuvant to the local anesthetic used in the combined Pectoralis Nerve Block II (PECS II) and stellate ganglion block for postoperative pain control in patients…
- Conditions
- Magnesium Sulfate, Local Anesthetic, Pectoral Nerve, Stellate Ganglion Block
- Trial name
- NCT06815887
- Testing
- Bupivacaine, Bupivacaine + Magnesium sulfate
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Hip Fracture, Postoperative Pain
Fascia Iliaca vs Femoral Nerve Block in Hip Fracture Patients
Hip fractures are common orthopedic injuries, especially in older adults, and surgical repair such as hip arthroplasty is often required.
- Conditions
- Hip Fracture, Postoperative Pain, Peripheral Nerve Block, Femoral Nerve
- Trial name
- CPTH (NCT07597317)
- Testing
- Fascia Iliaca Compartment Block (FICB)
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Central Park Teaching Hospital, Lahore
Anesthesia, Nerve Block
Comparison of the Effect of Preoperative and Postoperative ESP and PVB on Postoperative Pain in VATS
The aim of this prospective controlled randomised clinical trial was to identify the analgesic method that is more effective than two different regional analgesia techniques routinely used for pain control after video-assisted…
- Conditions
- Anesthesia, Nerve Block, Pain, Postoperative, Thoracic Surgery, Video Assisted
- Trial name
- NCT06488014
- Testing
- Erector spina plan block (ESP), Paravertebral block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara University
Hip Surgery, Postoperative Pain Management
Comparison of Intermittent Bolus vs. Continuous Infusion PENG Block for Postoperative Pain in Hip Surgery
This retrospective study evaluates the effects of two different administration methods of the Pericapsular Nerve Group (PENG) Block on postoperative pain control, opioid consumption, and recovery in patients undergoing hip…
- Conditions
- Hip Surgery, Postoperative Pain Management, Pericapsular Nerve Group Block (PENG Block), Regional Anesthesia
- Trial name
- ICPENG (NCT06834243)
- Testing
- Intermittent Bolus PENG Block, Continuous Infusion PENG Block
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Onur Baran