Clinical trials: Neurological Condition
Delirium, Awakening, Post-Anesthesia Delayed
Validation and Reliability of the Turkish 4AT Scale for Post-Anesthesia Awakening Delirium
Background: Delirium is a common and serious condition in hospitalized patients that often leads to extended hospital stays and increased healthcare costs. Accurate and timely detection is essential for optimal patient outcome.
- Conditions
- Delirium, Awakening, Post-Anesthesia Delayed, Delirium, Postoperative, Nurse's Role
- Trial name
- NCT06187389
- Testing
- 1 Grups
- Where
- Turkey (Türkiye)
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Kilis 7 Aralik University
Symptomatic Irreversible Pulpitis (SIP), Dental Pain
Intraligamentary vs Inferior Alveolar Nerve Block for Pulpitis: A Randomized Clinical Trial
This multicenter randomized trial compares the clinical effectiveness of intraligamentary injection versus inferior alveolar nerve block (IANB) in patients with symptomatic irreversible pulpitis in mandibular molars.
- Conditions
- Symptomatic Irreversible Pulpitis (SIP), Dental Pain, Inferior Alveolar Nerve Block Failure, Local Anesthesia
- Trial name
- NCT07130760
- Testing
- Intraligamentary Injection, Inferior Alveolar Nerve Block
- Where
- 2 sites in Spain
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Aula Dental Avanzada
Korean, Male
The Effect of Education on Decreasing the Prevalence and Severity of Neck and Shoulder Pain
Neck and shoulder pain (NSP) is fairly common among high school students in Korea. Presumably, the high prevalence of NSP in Korean adolescents is a consequence of an inappropriate static position for a prolonged period of time.
- Conditions
- Korean, Male, Adolescents
- Trial name
- NCT01727960
- Testing
- Education and posture correction
- Where
- South Korea
- Volunteers
- 1,302 people, healthy volunteers welcome
- Sponsor
- Soonchunhyang University Hospital
Oral Proprioceptive Sensitivity and Upper Limb Kinesthetic Acuity
Oral Proprioceptive Sensitivity and Upper Limb Kinesthetic Acuity: A Pilot Study
The goal of this observational study is to investigate whether differences in oral proprioceptive sensitivity are associated with differences in kinesthetic acuity of the upper limbs in children.
- Trial name
- NCT07854314
- Testing
- Upper-Limb Kinesthetic Acuity Assessment, Effect of Auditory Stimulation on Visual Perception, Oral Proprioceptive Sensitivity Assessment
- Where
- Spain
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Sophie Román Richon
Trigger Finger, Pain
Vibratory Anesthesia in Trigger Finger Injections
This study aims to compare the effectiveness of the use of no topical anesthesia, topical coolant, and the use of vibration in the reduction of pain during trigger finger injections.
- Conditions
- Trigger Finger, Pain, Anesthesia, Local
- Trial name
- NCT05405452
- Testing
- Vibration Anesthesia Device by Blaine Labs, Gebauers Ethyl Chloride 100% Topical Spray
- Where
- 2 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Aging Well, Aging Problems
Aquatic Exercise for Cognition and Mobility in Older Adults
The purpose of this study is to assess the effects of an aquatic exercise program on cognition and physical function of older adults.
- Conditions
- Aging Well, Aging Problems, Cognitive Change, Gait, Unsteady
- Trial name
- NCT05501249
- Testing
- Aquatic Integrated Cognitive Motor Training
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Emily Dunlap
Effects of; Anesthesia, in Labor and Delivery, Pregnancy
Effects of Analgesic Techniques on Duration of Spontaneously Laboring Patients
The purpose of this study is to determine if there is a difference in the duration of the first stage of labor in nulliparous women in spontaneous labor with whom analgesia is maintained with a combined spinal epidural (CSE)…
- Conditions
- Effects of; Anesthesia, in Labor and Delivery, Pregnancy, Prolonged First Stage of Labor
- Trial name
- NCT01982838
- Testing
- Epidural de novo, CSE
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Chronic Pain, Spinal Cord Injuries
Effects of Spinal Cord Injury Exercise Guidelines
Over 85,000 Canadians live with a spinal cord injury (SCI). The vast majority experience chronic pain from neuropathic or musculoskeletal origins, with many reporting the pain to be more physically, psychologically and socially…
- Trial name
- NCT04160858
- Testing
- Exercise, Control
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Old Age; Atrophy, Inflammatory Response
Effects of Parmigiano Reggiano on Skeletal Muscle Damage in Older Adults
Aging is associated with the loss of muscle mass and function (sarcopenia) and reduced tissue regenerative capacity. Eccentric exercise (ECC) is a model of RET that can be used with the elderly, due to the ability of the muscle…
- Conditions
- Old Age; Atrophy, Inflammatory Response, Muscle Soreness
- Trial name
- NCT04872374
- Testing
- Parmigiano Reggiano, Whey Protein
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Padova
Progressive Supranuclear Palsy
Study About Safety and Efficacy of Coenzyme Q10 in Progressive Supranuclear Palsy
Study hypothesis: A 6-week p.o treatment with 5 mg/Kg Coenzyme Q10 is safe and tolerable,increases the brain's metabolism and ameliorates clinical symptoms in patients with PSP.
- Trial name
- NCT00328874
- Testing
- Coenzyme Q10
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- German Parkinson Study Group (GPS)
Endodontically Treated Teeth, Post Operative Pain
The Effect of Instrumentation and Obturation on Postoperative Pain in Retreatment
Objectives: The aim of this study was to assess postoperative pain in prospective randomized clinical trial comparing Reciproc or hand instrument and also different obturation techniques in one visit of endodontic retreatment.
- Trial name
- NCT04789343
- Testing
- Root canal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Marmara University
Pain Management, 3D Printing
The Effectiveness of the Three-dimensional Biochemical Activity Model of Pain
Aim: In this study, it was aimed to develop a pain biochemical activity model taken from a three-dimensional printer and fixed by applying epoxy resin and to investigate the effect of this model on nursing students' understanding…
- Conditions
- Pain Management, 3D Printing, Education Nursing
- Trial name
- NCT07389382
- Testing
- 3D printed pain biochemical activity training model, PowerPoint Presentations
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Hearing Loss
Restoration of Spectral Resolution With Hearing-aid Amplification
The objective of this study protocol is to determine the efficacy of using aided measures of spectral resolution to set the dynamic range of hearing with hearing-aid amplification.
- Trial name
- NCT03850678
- Testing
- Hearing Aid
- Where
- United States
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Chronic Pain
Prevalence of Pain Disorders in Employees of French Furniture Shop.
In France, the Direction of Research, Studies, Evaluation and Statistics, in their 2015 report on "Chronic pain: the state of health of the population in France - Indicators associated with the Public health ", shows that 34.6%…
- Trial name
- PREVADouleur (NCT03277885)
- Testing
- chronic pain
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Anhedonia, Depression
Sleep and Healthy Aging Research on Depression for Younger Women
Compelling evidence indicates inflammation plays a role in depression, but potential mechanisms linking inflammation to depression, such as dysregulated reward processing, are poorly understood.
- Trial name
- NCT03848715
- Testing
- Endotoxin
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Neurological Disease, Motor Disorders
Technological Devices and Home Automation System in Neurological Rehabilitation
The use of home automation system may be useful in rehabilitation to collect data about the environment and the amount of therapy.
- Trial name
- SMART (NCT06270420)
- Testing
- Technological Motor Rehabilitation
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Shoulder Pain, Neuromuscular Diseases
Understanding Control and Mechanisms of Shoulder Instability in FSHD
The aim of this study is to identify factors for shoulder instability in people with Facioscapulohumeral dystrophy (FSHD). FSHD is a non-life limiting condition with symptoms presenting in the second decade of life (Evangelista…
- Conditions
- Shoulder Pain, Neuromuscular Diseases, Shoulder Injuries, Facio-Scapulo-Humeral Dystrophy
- Trial name
- NCT05239520
- Testing
- 3D movement analysis with surface electromyography and ultrasound
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Chronic Pain, Pain
Classifying and Predicting Long-term Pain and Function in Older Adults
This project will use novel methods to detect clinically meaningful subgroups of older adults based on long-term trajectories of bothersome pain and function.
- Trial name
- NCT04864223
- Where
- United States
- Volunteers
- 6,783 people, healthy volunteers welcome
- Sponsor
- University of Washington
Pain, Postoperative
TOTEM: Trial of TAP Block Effective Medications
Our goal is to determine if liposomal bupivacaine compared to standard bupivacaine results in increased pain control and decreased narcotic pain medication use when used in TAP blocks prior to laparoscopic hysterectomies for…
- Trial name
- TOTEM (NCT04382859)
- Testing
- Transversus abdominis plane (TAP) block with liposomal bupivacaine
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Western Michigan University School of Medicine
Local Analgesia Via Infiltration, Wound Heal
Comparison of Postoperative Effects of Articaine and Lidocaine in Mucogingival Surgery
The aim of this study is to compare and evaluate the effects of using lidocaine 2% (with adrenaline) and articaine 4% (with adrenaline) in free gingival graft (FGG) surgery on postoperative wound healing, changes in blood flow in…
- Conditions
- Local Analgesia Via Infiltration, Wound Heal, Pain, Postoperative, Hemorrhage
- Trial name
- NCT07145879
- Testing
- Lidocaine hydrochloride 2% with epinephrine 1:100 000, Articaine 4% with epinephrine 1:100,000, Free gingival graft (FGG)
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
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