Clinical trials: Neurological Conditions
Pain, Postoperative
Bioequivalence Between Integrated E-TRANS (Fentanyl) System and Separated (Two-Part) E-TRANS (Fentanyl) System
The purpose of this study is to confirm that the two forms of the device the Integrated E-TRANS (fentanyl HCl) system and the Separated (Two-Part) E-TRANS (fentanyl HCl) System provide the equivalent blood levels of medication…
- Trial name
- NCT00990418
- Testing
- Separated (Two Part) E-TRANS (fentanyl HCl) System; Integrated E-TRANS (fentanyl HCl) System
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alza Corporation, DE, USA
Acute Pain
Safety of Hydromorphone in Adult Patients Presenting to the Emergency Department With Acute Severe Pain
The purpose of this study is to determine the safety and speed of onset of 2mg intravenous hydromorphone (Dilaudid) in patients weighing at least 150 lbs presenting to the emergency department with acute severe pain
- Trial name
- NCT00305110
- Testing
- 2 mg IV hydromorphone
- Where
- United States
- Volunteers
- 298 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Smoking ( Cigarette), Women
Smoking, Pain Threshold, and Hand Strength in Women
This study aims to investigate the effects of smoking on pain threshold, cervical position sense, and grip strength in women. Measurements will include pressure pain threshold (PPT), cervical position sense (CPS), grip strength…
- Conditions
- Smoking ( Cigarette), Women, Pain
- Trial name
- NCT07611760
- Testing
- observational study
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Primary Dysmenorrhea
TENS on Pain Intensity in Primary Dysmenorrhea
Dysmenorrhoea is a common problem in women of reproductive age. It is associated with painful uterine contractions and discomfort.
- Trial name
- TENSinPain (NCT03446859)
- Testing
- TENS
- Where
- Nigeria
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Obafemi Awolowo University
Strabismus
Mobile Medical Application for Cost-effective Strabismus Screening
Develop and evaluate a new smartphone based app to screen for and measure eye misalignment (strabismus). The investigators will validate the app against simulated strabismus of known magnitude and common clinical tests.
- Trial name
- NCT03450980
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Postoperative Delirium, Postoperative Cognitive Dysfunction
Greek Validation of ACE III Test in Perioperative Patients
Postoperative neurocognitive disorders, including postoperative delirium (POD) and postoperaive cognitive dysfunction (POCD), are common complications of perioperative neurocognition in elderly patients undergoing surgery.
- Trial name
- NCT04312516
- Where
- Greece
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Fear, Pain
The Effect of Using Finger Puppets and Showing Cartoons on Pain and Fear in Preschool Children During Blood Collection
The study is a randomized controlled experimental study aimed at determining the effect of showing cartoons or using finger puppets to children aged 3-6 years before taking venous blood samples on their pain levels.
- Trial name
- NCT07237074
- Testing
- showing finger puppets during blood collection, cartoons, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hitit University
Chronic Metabolic Disorder, Lipid Metabolism Disorders
Randomized Clinical Trial of HMR(Home Meal Replacement)-Type Omega-3-balanced-diet
Investigate whether HMR(Home meal replacement)-type omega-3-balanced-diet can improve clinical laboratory values related to chronic metabolic diseases through reducing lipids and chronic inflammation, and can prevent muscle loss.
- Conditions
- Chronic Metabolic Disorder, Lipid Metabolism Disorders, Sarcopenia
- Trial name
- NCT04552574
- Testing
- HMR(Home meal replacement)-type omega-3-balanced diet
- Where
- South Korea
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Chungbuk National University Hospital
Pain, Nosalabial Folds Correction
The Safety and Efficacy of Using HYADERMIS LA for Wrinkle Correction
The study is a double-blind, randomized, within-subject controlled, 2-armed, single-centre study sponsored by SciVision Biotech Inc. and approved by Yuan's General Hospital Institutional Review Board.
- Trial name
- NCT02128204
- Testing
- lidocaine contained hyaluronate facial dermal filler, hyaluronate facial dermal filler
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- SciVision Biotech Inc.
Hyperalgesia, Pain
Effect of High Dose Naloxone on Secondary Hyperalgesia
Recent studies have focused on the role of endogenous opioids on central sensitization. Central sensitization is known to be impaired or altered in chronic pain conditions, as fibromyalgia or chronic tension headache.
- Conditions
- Hyperalgesia, Pain, Naloxone, Opioid Antagonist
- Trial name
- NCT01935206
- Testing
- Naloxone (2 mg/kg)
- Where
- 2 sites in Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Sleep Deprivation
Effect of Work Load and Sleep Deprivation on Medical Staff's Driving Skills
Long and unorthodox working hours (e.g. 24 hours or 23pm-07am shifts for doctors and nurses respectively) combined with sleep deprivation, may affect cognitive functions such as response time and concentration.
- Trial name
- NCT00849706
- Testing
- Study participants will work their regular shifts, and tested after night shifts.No shifts will be added because of the study.
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Blindness
A Study to Evaluate the BrainPort Vision Device in Individuals Blinded by Traumatic Injury
The BrainPort V200 Device is a wearable, non-surgical, prosthetic device intended for people who are profoundly blind. The BrainPort V200 translates images captured by a digital camera into electro-tactile stimulation presented…
- Trial name
- NCT02393118
- Testing
- BrainPort V200 Device
- Where
- 3 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wicab
Non Sarcopenic Subjects, Possible Sarcopenia
Association Between Oral Hypofunction, Sarcopenia and Social Frailty in Community-dwelling Older Adults
Previous studies have provided a preliminary understanding of the likelihood of sarcopenia and the prevalence of sarcopenia in the elderly in the community.
- Conditions
- Non Sarcopenic Subjects, Possible Sarcopenia, Sarcopenia(With Low ASM by BIM)
- Trial name
- OSSF (NCT07658625)
- Testing
- Non interventional study
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chang Gung University of Science and Technology
IUD Insertion
Comparison of Pain Level During Intrauterine Device (IUD) Insertion Between Conventional and Direct Method
The so-called "direct" method of intrauterine device (IUD) and intraintuerine system (IUS) insertion is increasingly used. A study has shown that it is technically simpler and assumes less painful than the classic pose.
- Trial name
- KIDDS (NCT03473717)
- Testing
- classic method, direct method
- Where
- 10 sites in France
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pain, Face
First-in-man Imaging of a New PET Radiotracer for Oxytocin Receptors
The investigators will test a new positron-emitting radiotracer to determine whether it is suitable for studying the oxytocin receptor by positron emission tomography (PET) in humans.
- Trial name
- NCT06955650
- Testing
- Imaging procedure to measure the distribution of a newly developed radiolabeled ligand for the oxytocin receptor
- Where
- Denmark
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Central Sensitisation, Elbow Pain
Relation Between Temporal Summation and Fatigue
Central sensitization (CS) is a common feature in chronic musculoskeletal pain conditions including rheumatoid arthritis, chronic whiplash syndrome, fibromyalgia, temporomandibular joint disorders, low back pain and lateral elbow…
- Conditions
- Central Sensitisation, Elbow Pain, Fatigue
- Trial name
- NCT05146960
- Testing
- Temporal summation
- Where
- Belgium
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University Ghent
Impacted Wisdom Tooth, Pain
Investigation of Effectiveness of Local Antibiotic With Platelet Rich Fibrin on Third Molar Surgery Outcomes In Vivo
The aim of this study was investigate the effectiveness of Local Antibiotic Applications With Platelet Rich Fibrin on Third Molar Surgery Outcomes In Vivo and In Vitro.
- Conditions
- Impacted Wisdom Tooth, Pain, Staphylococcus Aureus
- Trial name
- NCT05678296
- Testing
- Diagnosis, Analgesic, traditional osteotomies
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ceren Melahat Donmezer
Down Syndrome, Speech and Language Disorder
Building Sentences With Preschoolers Who Use AAC
The focus of this investigation is to compare the effectiveness of the AAC Generative Language Intervention approach to an AAC Standard of Care condition on preschool sentence productions.
- Conditions
- Down Syndrome, Speech and Language Disorder, Speech Disorders in Children, Speech Intelligibility
- Trial name
- NCT03538925
- Testing
- AAC Generative Language Intervention, Standard of Care / Business as Usual
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Developmental Articulation Disorder, Stuttering
Study of Brain Activity During Speech Production and Speech Perception
The purpose of this study is to gain a better understanding of the brain's activity and organization in the development of speech disorders.
- Trial name
- NCT00004991
- Where
- United States
- Volunteers
- 411 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Low Back Pain
Effects of Tactile Stimuli for Lumbar Multifidus Muscle Activation in Healthy Adults and Patients With Low Back Pain
The purpose of this study is to compare combined tactile stimulation and verbal instruction to verbal instruction only on lumbar multifidus muscle activation in asymptomatic healthy adults and in patients with LBP.
- Trial name
- NCT02836860
- Testing
- Tactile stimuli
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Texas Woman's University
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