Clinical trials: Neurological Impairment
Urinary Incontinence, Sarcopenia
The Urinary Incontinence Treatment Study
Investigators plan a prospective cohort study with an adaptive design based on physical function status. The design will involve tracking the number of women recruited with physical function impairment and those without any…
- Trial name
- UNITS (NCT03057834)
- Testing
- Pelvic floor muscle exercise
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Sleep Deprivation
A Change in Diet May Decrease the Negative Consequences of Chronic Sleep Deprivation
The purpose of this study is to determine whether or not a low calorie, low glycemic index diet with omega-3 fatty acid supplements can prevent some of the negative consequences of sleep deprivation.
- Trial name
- NCT00123214
- Testing
- Controlled Dietary Intervention
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- St. Vincent's Medical Center
Dyslexia, Developmental, Reading
Enhancing Letter-Speech Sound Learning and Reading Network Activation With Transcranial Electrical Stimulation
This study investigates the effects of transcranial electrical stimulation (tES) on the brain and its potential to enhance reading-related learning.
- Conditions
- Dyslexia, Developmental, Reading, Dyslexia, Learning
- Trial name
- LexiStim (NCT07546292)
- Testing
- Transcranial random noise stimulation
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Silvia Brem
Motor Disorders, Healthy
Non-invasive BCI-controlled Assistive Devices
Injuries affecting the central nervous system may disrupt the cortical pathways to muscles causing loss of motor control. Nevertheless, the brain still exhibits sensorimotor rhythms (SMRs) during movement intents or motor imagery…
- Conditions
- Motor Disorders, Healthy, Spinal Cord Injuries, Muscular Diseases
- Trial name
- NCT05183152
- Testing
- NMES Feedback, Visual Feedback, TESS
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Visual Impairment
mHealth Intervention for Improving Eye Health at Community Level
This study is a community trial that aims to establish and evaluate an mHealth screening and promotional tool for improving eye health in Iran.
- Trial name
- Vison mHealth (NCT03922347)
- Testing
- Screening program including 2 consecutive tests, Screening program with mobile health
- Where
- Iran
- Volunteers
- 3,300 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Hearing Impairment
Do Bluetooth Noise Cancelling Headphones Improve the Quality of Care in Hearing Impaired Patients?
Participants will be recruited by performing chart reviews of patients to be seen at University of Texas Medical Branch at Galveston Ophthalmology and Optometry Clinic. A sample size of at least 30 patients is needed (60 eyes).
- Trial name
- NCT05420038
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Hearing Loss, Bilateral Sensorineural, Pulmonary Function
Comparison of Pulmonary Functions and Respiratory Muscle Strength Between Children With Hearing Impairment and Healthy Peers
This study aims to compare pulmonary function and respiratory muscle strength between children with hearing impairment and their healthy peers.
- Conditions
- Hearing Loss, Bilateral Sensorineural, Pulmonary Function, Respiratory Muscle Strength, Children
- Trial name
- NCT07421349
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Body Composition, Beneficial, Paresis
Meal Patterning on Weight Loss With Changes to Body Comp, Muscle and Metabolic Health
About two-thirds of adults in the United States are overweight or obese with likely adverse health consequences. A Moderate weight loss by dieting and exercise is recommended to improve health.
- Conditions
- Body Composition, Beneficial, Paresis, Impaired Glucose Tolerance
- Trial name
- S38 (NCT02066948)
- Testing
- wt loss, Meal Pattern, even
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Purdue University
Dementia of Alzheimer Type, Alzheimer Disease, Late Onset
Genetic Studies in Familial Dementia
The purpose of this study is to identify genetic factors that contribute to or cause dementia (loss of memory) and related disorders across all ages and ethnic groups.
- Conditions
- Dementia of Alzheimer Type, Alzheimer Disease, Late Onset, Alzheimer Disease, Early Onset, Mild Cognitive Impairment
- Trial name
- NCT04680013
- Where
- United States
- Volunteers
- 4,884 people, healthy volunteers welcome
- Sponsor
- University of Miami
Neurologic Deficits, Neurologic Disorder
NeuroSeq: A Prospective Trial to Evaluate the Diagnostic Yield of Whole Genome Sequencing (WGS) in Adult Neurology
Prospective, multi-site, single-arm study to evaluate the diagnostic yield of cWGS in adults with neurological disorders. A single cohort naive of genetic testing will receive standard of care testing for 180 days followed by…
- Conditions
- Neurologic Deficits, Neurologic Disorder, Neurologic Abnormalities
- Trial name
- NeuroSEQ (NCT04170985)
- Testing
- clinical Whole Genome Sequencing
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Illumina, Inc.
Memory Impairment
Vilazodone for Corticosteroid-Induced Memory Impairment
The purpose of this study is to examine whether vilazodone attenuates the memory and mood effects of corticosteroids on the human hippocampus in 24 healthy controls.
- Trial name
- NCT01828515
- Testing
- Vilazodone, Hydrocortisone
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Alzheimer Disease, Mild Cognitive Impairment
Tau Imaging With JNJ067
This protocol is designed to assess the utility of a new positron emission tomography (PET) radiopharmaceutical to image tau, [18F] JNJ067, invented by Janssen Pharmaceutical companies of Johnson \& Johnson.
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Progressive Supranuclear Palsy
- Trial name
- NCT03926702
- Testing
- Radiopharmaceuticals
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Delirium, Cognitive Impairment
Preoperative BAMCOG and Cortisol and Postoperative DeltaScan in AVR Patients (Aortic Valve Replacement)
There is lack of attention to preoperative cognitive function and delirium in elderly who underwent surgery. The investigators are investigating different tools that can help to screen for cognitive dysfunction and delirium in…
- Conditions
- Delirium, Cognitive Impairment, Cognitive Dysfunction, Cognitive Dysfunction, Postoperative
- Trial name
- NCT05209555
- Testing
- MoCA, BAMCOG, DeltaScan
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Catharina Ziekenhuis Eindhoven
Mild Cognitive Impairment, Mild Dementia
Assessing Cognitive Decline at Home
Neuropsychiatric symptoms (NPS) refer to a range of mental and emotional issues that can be observed through how patients move, perform daily tasks, and express feelings on their faces.
- Conditions
- Mild Cognitive Impairment, Mild Dementia, Dementia Alzheimers, Dementia
- Trial name
- NCT06704971
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Stanford University
Mild Cognitive Impairment
Cognitive Stimulation Therapy and Olderly People With Mild Cognitive Impairment
The aim of this study is to examine the effect of cognitive stimulation therapy on cognitive status and apathy in elderly individuals with mild cognitive impairment.
- Trial name
- NCT06115785
- Testing
- Cognitive Stimulation Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ejdane Coskun
Binocular Vision Disorder, Visual Impairment
Evaluation of Tests Performance on a New Digital Orthoptic Platform
This clinical trials aims to evaluate Tests Performance on a New Digital Orthoptic Platform.
- Trial name
- ESPPADON (NCT02651389)
- Where
- France
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Feeding Behavior, Sensory Integration Disorder
Feeding Behavior Intervention in Children with Cerebral Visual Impairment
This study was planned to investigate the effects of nutritional education given in addition to sensory integration intervention on feeding behavior, sensory processing and developmental areas in children with Cerebral Visual…
- Conditions
- Feeding Behavior, Sensory Integration Disorder, Cerebral Visual Impairment
- Trial name
- NCT06827743
- Testing
- feeding behavior education, Sensory integration intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Trakya University
Memory Disturbances
Functional Magnetic Resonance Imaging Study of Jaw-tapping Movement on Memory Function
The purpose of this study is to examine the possibility of using jaw-tapping training as a self-exercise for developing memory and preventing dementia in elderly subjects with memory disturbances using functional magnetic…
- Trial name
- NCT01873664
- Testing
- Jaw-tapping
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kyunghee University Medical Center
Developmental Language Disorder, Specific Language Impairment
Retrieval-Based Word Learning in Developmental Language Disorder During Book Reading
Children with developmental language disorder (DLD; also referred to as specific language impairment) experience a significant deficit in language ability that is longstanding and harmful to the children's academic, social, and…
- Conditions
- Developmental Language Disorder, Specific Language Impairment, Language Development
- Trial name
- NCT06026124
- Testing
- Retrieval-based word learning: Repeated Spaced Retrieval condition, Retrieval-based word learning: Repeated Study condition
- Where
- 2 sites in United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Purdue University
Hearing Loss, Age-Related
Early Identification of Age-related Hearing Impairment
The need for future hearing rehabilitation is enormous. World Health Organization (WHO 2021) has estimated that by 2050, 2.5 billion people will have some degree of hearing loss, and 1/4 of them will require hearing…
- Trial name
- NCT06418321
- Testing
- Investigational device, Audiometer, Otomicroscopy
- Where
- 2 sites in Finland
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Aalto University