Clinical trials: Neurological Outcome
Hypoxic-Ischemic Encephalopathy, Post-Cardiorespiratory Arrest Coma
Cerebral Oxymetry and Neurological Outcome in Therapeutic Hypothermia
This study is designed to assess the effect of cerebral oxygen saturation as an early predictor of neurological outcomes in patients undergoing therapeutic hypothermia after cardiac arrest
- Conditions
- Hypoxic-Ischemic Encephalopathy, Post-Cardiorespiratory Arrest Coma, Cardiac Arrest
- Trial name
- NCT03024021
- Testing
- Near-infrared spectroscopy (NIRS) (INVOS®, Covidien)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Tepecik Training and Research Hospital
Traumatic Brain Injury
Effectiveness of Amantadine Hydrochloride for Treatment of Severe Traumatic Brain Injury (TBI)
This is a controlled trial of amantadine to improve level of function following severe traumatic brain injury. The purpose of this study is: 1.
- Trial name
- NCT00970944
- Testing
- Amantadine Hydrochloride
- Where
- 11 sites in United States, Denmark and 1 more
- Volunteers
- 184 people
- Sponsor
- JFK Medical Center
Low Back Pain
Influence of Kinesiophobia on the Outcome of Chronic Low Back Pain Condition
Though large body of evidence reported association between pain and kinesiophobia, there are paucity of studies in associating kinesiophobia to muscle endurance and position sense in patients with Chronic lower back pain [CLBP].
- Trial name
- NCT05079893
- Testing
- Case control study
- Volunteers
- 600 people
- Sponsor
- Gulf Medical University
Stroke, Upper Extremity Dysfunction
Implementing Outcome Measures in Stroke Rehabilitation
The primary objective of this study is to tailor and test implementation strategies to support the adoption of two upper extremity motor outcome measures for stroke: the Fugl-Meyer Assessment and the Action Research Arm Test.
- Conditions
- Stroke, Upper Extremity Dysfunction, Hemiplegia, Hemiparesis
- Trial name
- I-STROM (NCT04888416)
- Testing
- I-STROM
- Where
- United States
- Volunteers
- 484 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Agitation
The Effect of Intravenous Fentanyl Prior the End of Surgery on Emergence Agitation in Paediatric Patients After General Anesthesia
The propose of this study is to determine the effect of intravenous fentanyl prior the end of surgery on the incidence and severity of EA in pediatric patient.
- Trial name
- NCT01440114
- Testing
- fentanyl, NSS
- Where
- Thailand
- Volunteers
- 144 people
- Sponsor
- Prince of Songkla University
Anesthesia, Local, Anesthesia
General Anesthesia and Paravertebral Blocks vs. General Anesthesia Only: Influence Inflammation Factors and Clinical Outcomes in Modified Radical Mastectomy
Regional anesthesia and analgesia may maintain immune function, reduce surgical stress, and also reduce volatile anesthetics and opioids requirements.
- Conditions
- Anesthesia, Local, Anesthesia, Inflammatory Response, Pain, Postoperative
- Trial name
- NCT04540055
- Testing
- Paravertebral block, General Anesthesia
- Where
- Indonesia
- Volunteers
- 88 people
- Sponsor
- Udayana University
Chronic Neck Pain
Cross-cultural Adaptation and Validation of Arabic Version of COMI in Patients With Chronic Neck Pain
PURPOSE: To translate, validate and examine the psychometric properties of the Arabic version of the COMI in Egyptian patients with neck pain.
- Trial name
- NCT04136964
- Testing
- Neck COMI
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Stable Angina (SA), NSTE-ACS (NSTEMI and UA)
Utilisation of Angiox® in European Practice
The objective of this study is to determine utilisation patterns in patients receiving Angiox® in participating European centres.
- Conditions
- Stable Angina (SA), NSTE-ACS (NSTEMI and UA), STEMI (STE-ACS)
- Trial name
- EURO-vision (NCT01011504)
- Where
- 2 sites in France, Germany
- Volunteers
- 2,019 people
- Sponsor
- The Medicines Company
Intraoperative Pain
Management of Indwelling Labor Epidural Catheters for Cesarean Delivery
This is a prospective observational study that will survey patients who had an indwelling labor epidural catheter and subsequently underwent cesarean delivery.
- Trial name
- NCT07366307
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Headache, Cervical Radiculopathy
Outcomes After Surgery for Degenerative Cervical Radiculopathy in Patients with Concurrent Headache
Surgery for degenerative cervical radiculopathy (DCR) is one of the most common causes of neck surgery. The typical surgical indication is radicular pain (arm pain) caused by nerve impingement.
- Trial name
- NCT06885216
- Testing
- Anterior cervical discectomy and fusion/ posterior decompression
- Volunteers
- 12,000 people
- Sponsor
- University Hospital of North Norway
Stroke, Gait Disorders, Neurologic
Technological Balance and Gait Rehabilitation in Patients With Stroke Sequelae: Functional, Motor and Cognitive Outcomes
Stroke represents the leading cause of disability worldwide, with a significant impact on an individual, family, and economic impact.
- Conditions
- Stroke, Gait Disorders, Neurologic, Balance
- Trial name
- ROAR-S (NCT05280587)
- Testing
- Technological Rehabilitation
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Tinnitus, Subjective, Sudden Deafness
The Study on Effect and Neural Network Mechanism of Transcranial Direct Current Stimulation for Sudden Deafness With Tinnitus
This clinical study is prospective, single-center, randomized, controlled, double-blind clinical trail, which entitled transcranial electrical stimulation for the treatment of acute tinnitus approved by Sun Yat-sen University…
- Conditions
- Tinnitus, Subjective, Sudden Deafness, Transcranial Direct Current Stimulation, Double-Blind Method
- Trial name
- NCT05964725
- Testing
- Receive traditional medical therapy and transcranial direct current stimulation
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Type 2 Diabetes Mellitus, Obesity
The TRIABETES - ARMMS-T2D Study: A Randomized Trial to Compare Surgical and Medical Treatments for Type 2 Diabetes
This research study is being performed to begin to determine the effectiveness of two dominant bariatric surgery procedures versus an intensive lifestyle intervention to induce weight loss in patients and promote improvements in…
- Trial name
- TRIABETES (NCT01047735)
- Testing
- Roux-en-Y Gastric Bypass Surgery, Laparoscopic Adjustable Gastric Banding, Lifestyle Weight Loss Intervention
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Pittsburgh
Morbid Obesity
Does Body Mass Index Impact the Outcome of Dural Puncture Epidural in Parturients Undergoing Normal Vaginal Delivery
Recently, the dural puncture epidural (DPE) technique has emerged as a novel method of labor analgesia. The DPE technique is a modification of the combined spinal epidural (CSE) technique, where a dural perforation is created…
- Trial name
- NCT04963452
- Testing
- Dural puncture epidural
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Ain Shams University
Sepsis, Sleep Deprivation
the Relationship of the Use of Eye Masks and Outcomes of Patients With Sepsis in Intensive Care Unit
The aim of the study is to investigate the relationship of nocturnal use of eye masks and immune function, cerebral function and outcomes of patients with sepsis.
- Conditions
- Sepsis, Sleep Deprivation, Immune Suppression
- Trial name
- NCT02304224
- Testing
- eye masks
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai 10th People's Hospital
Neurological Outcome, Cardiac Arrest
Out-of-hospital Cardiac Arrest (OHCA) Biomarkers
Few early prognostic indicators are currently available for patients' families and clinicians following out of hospital cardiac arrest (OHCA), and blood biomarkers may be of prognostic value in these cases.
- Conditions
- Neurological Outcome, Cardiac Arrest, Out-Of-Hospital Cardiac Arrest, Brain Anoxia Ischemia
- Trial name
- NCT03112486
- Testing
- blood draw
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Florida
Orbital Fractures, Blow Out Fracture of Orbit
Orbital Fractures Registry
Approximately 300 patients presenting orbital blow-out fracture will be enrolled prospectively in this registry. All patients, surgically and nonsurgically treated as per standard (routine) of care will be followed-up (FU) within…
- Trial name
- OFx (NCT03887988)
- Testing
- Primary "early" reconstruction, Nonsurgical, Primary "delayed" reconstruction
- Where
- 14 sites in United States, Germany and 10 more
- Volunteers
- 300 people
- Sponsor
- AO Innovation Translation Center
Chronic Pain
Integrative Medicine for Chronic Pain
In this study, the effects of a 14-day inpatient treatment in an internal medicine ward for integrative medicine on pain, disability, quality of life, satisfaction with life, depression, and anxiety will be investigated.
- Trial name
- POSITIVE (NCT02038244)
- Testing
- Multimodal integrative medicine inpatient treatment program
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- Universität Duisburg-Essen
Pain, Chronic
Prediction of Clinical Outcome in Axillary Block
The primary endpoint of this study was to identify that Perfusion index (PI) has any predictive value for the treatment outcome of cervical radiculopathy
- Trial name
- NCT05723419
- Testing
- axillary block using 5 ml local anesthetics
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Keimyung University Dongsan Medical Center
Low Back Pain
Prognostic Factors of a Favorable Outcome Following an Exercise Program for Soldiers With Low Back Pain
Low back pain (LBP) encompasses heterogeneous patients unlikely to respond to a unique treatment. Identifying sub-groups of low back pain may help to improve treatment outcomes.
- Trial name
- NCT03464877
- Testing
- Multi-station full-body supervised exercise program
- Where
- Canada
- Volunteers
- 104 people
- Sponsor
- Marc Perron