Clinical trials: Neuromuscular Blockade Monitoring, open to volunteers
Obesity
Comparison of Acceleromyography and Electromyography in Obese Patients Undergoing General Anesthesia
The goal of this prospective observational study is to compare two different methods of monitoring muscle relaxation during anesthesia - acceleromyography (AMG) and electromyography (EMG) - in people with obesity who are having…
- Trial name
- OBAEG (NCT07283354)
- Testing
- Neuromuscular monitoring with electromyography (EMG), Neuromuscular monitoring with acceleromyography (AMG)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Padova
Postoperative Residual Curarization, Neuromuscular Block Prolonged
Postoperative Residual Neuromuscular Block and Passive Smoke Exposure in Pediatric Dental Patients
Postoperative residual neuromuscular block (PRNB) may persist despite apparent clinical recovery from neuromuscular blockade and may increase the risk of postoperative respiratory complications.
- Trial name
- NCT07831434
- Testing
- Passive Smoke Exposure
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Istanbul University - Cerrahpasa
Neuromuscular Blockade Reversal Agent, Perioperative Complications
Sugammadex-Induced Clenching During Neuromuscular Blockade Reversal
Study Objective: This study aims to evaluate the incidence, severity, and risk factors of sugammadex-induced mouth clenching during neuromuscular blockade (NMB) reversal in adult surgical patients.
- Conditions
- Neuromuscular Blockade Reversal Agent, Perioperative Complications, Anesthesia, General, Sugammadex
- Trial name
- NCT06962007
- Testing
- Sugammadex 1 mg/kg Group, Sugammadex 2 mg/kg Group, Sugammadex 4 mg/kg Group
- Where
- South Korea
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
Neuromuscular Blockade
Comparison of an Acceleromyography- and Electromyography-based Neuromuscular Monitor With TOF-Watch ® Monitor
A quantitative neuromuscular monitoring device is desirable to titrate the depth of neuromuscular block (NMB) during a procedure, and to prevent residual effects after removal of the endotracheal tube.
- Trial name
- NCT05632107
- Testing
- TOF-Watch®；DELSYS® Wireless surface EMG
- Where
- 2 sites in China
- Volunteers
- 100 people
- Sponsor
- Huazhong University of Science and Technology
Neuromuscular Blockade Monitoring, NMT
NMT EasyFit Sensor and Cable
The purpose of this clinical study is to collect and assess feedback from clinical users regarding the functionality and device use and collection of raw parameter date from the NMT Sensor and NMT Cable.
- Trial name
- NCT07394140
- Testing
- Collection of NMT Technology
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- GE Healthcare
Major Depressive Disorder, Bipolar Disorder
Venous Tourniquet vs. Arterial Tourniquet for Seizure Monitoring in ECT
This prospective, open-label clinical trial aims to compare a novel "Venous Tourniquet with Regional Low-Dose Sugammadex" method against the gold standard "Arterial Tourniquet" (Isolated Forearm Technique - IFT) for monitoring…
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Schizophrenia
- Trial name
- NCT07534475
- Testing
- Device: Arterial Tourniquet, Device: Venous Tourniquet, Sugammadex
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Medipol University
Neuromuscular Blocking Agents, Residual Neuromuscular Block
Measuring of the Duration of Action of Different Doses of Rocuronium-induced Neuromuscular Block in Infants During Surgical Treatment of Craniosynostosis
The use of intravenous muscle relaxants during anaesthesia can significantly facilitate endotracheal intubation and reduce the chance of possible airway complications during intubation.
- Conditions
- Neuromuscular Blocking Agents, Residual Neuromuscular Block, Neuromuscular Blockade Monitoring
- Trial name
- NCT07080528
- Testing
- Sevofluorane, Propofol
- Where
- Hungary
- Volunteers
- 20 people
- Sponsor
- Tamas Vegh, MD
Neuromuscular Blockade, Cholecystectomy
Acceleromyography Versus Electromyography for Neuromuscular Recovery Assessment at the End of Surgery
This prospective observational study aims to evaluate the agreement between acceleromyography and electromyography for measuring train-of-four (TOF) ratio at the end of surgery before reversal of neuromuscular blockade.
- Trial name
- NCT07739862
- Testing
- Simultaneous Acceleromyography and Electromyography Monitoring
- Where
- Chile
- Volunteers
- 70 people
- Sponsor
- Clínica Dávila
Neuromuscular Blockade, Statin-Associated Myopathy
Evaluation of Neuromuscular Blockade Responses in Statin-Using and Non-Using Patients
This study aims to compare the neuromuscular blockade responses in patients undergoing elective surgery under general anesthesia, with a focus on the use of statins.
- Conditions
- Neuromuscular Blockade, Statin-Associated Myopathy, Neuromuscular Monitoring
- Trial name
- NCT06834776
- Testing
- TOF (Train-of-Four) monitoring for depth of neuromuscular blockade.
- Volunteers
- 104 people
- Sponsor
- Ankara City Hospital Bilkent
ARDS, TTM
TwichView-guided Atricurium Dose Adjustment Trial
The goal of this clinical trial is to learn if using a monitor that measures muscle response can lower the amount of muscle relaxant medicine needed in adults who are treated in an intensive care unit (ICU) and need a continuous…
- Conditions
- ARDS, TTM, ECMO, Neuromuscular Blockade Monitoring
- Trial name
- NCT07807046
- Testing
- EMG-based quantitative TOF-guided atracurium titration
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Fu Jen Catholic University Hospital
Neuromuscular Blocking Agents
Antagonism of Neostigmine in Continuous Infusion of Mivacurium
In this study, the antagonism of neostigmine, a cholinesterase inhibitor, on continuous infusion of mivacurium during foot and ankle surgery under general anesthesia was investigated, and the appropriate time point of antagonism…
- Trial name
- NCT07524959
- Testing
- Neostigmine
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Beijing Tongren Hospital
Polyneuropathies
Diagnostic Feasibility of 100 Hz Tetanic Stimulation
The goal of this observational study is to investigate the applicability of 100 Hz tetanic stimulation with an electromyography device in the exclusion of postoperative residual neuromuscular block.
- Trial name
- NCT06754995
- Where
- 2 sites in Hungary
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Debrecen
Driving Pressure, Neuromuscular Blockade Monitoring
Effect of Neuromuscular Block Depth on Driving Pressure and Postoperative Respiratory Events in Abdominal Surgeries
This randomized controlled study aims to evaluate the effects of deep versus moderate neuromuscular blockade on intraoperative driving pressure and the development of postoperative critical respiratory events in patients…
- Conditions
- Driving Pressure, Neuromuscular Blockade Monitoring, Postoperative Respiratory Complications
- Trial name
- NCT07464288
- Testing
- Rocuronium
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Mechanomyography, Neuromuscular Blockade Monitoring
The TOF3D Mechanomyograph. Evaluation of a New Device for Assessment of the Neuromuscular Block.
In clinical anesthesiologic practice, most institutions use acceleromyography in order to assess the degree of a neuromuscular block. The aim of the present study is to assess a new device using mechanomyography.
- Trial name
- MMG versus AMG (NCT07371377)
- Testing
- measurement of the time course of a neuromuscular block
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Klinikum Hersfeld-Rotenburg
Neuromuscular Blockade Monitoring
Monitoring of Neuromuscular Blockade in the Intensive Care Unit: a Reliability Study
The objective of this clinical trial is to evaluate the reliability of neuromuscular blockade monitoring in adult intensive care patients depending on the clinical context.
- Trial name
- CURAREA (NCT07741851)
- Testing
- neuromuscular blockade monitoring
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Centre Hospitalier Intercommunal Aix-Pertuis
Surgery, Neuromuscular Blockade
TetraGraph to Evaluate Onset and Recovery Times of Rocuronium
In most clinical instances, direct laryngoscopy and endotracheal intubation is performed after a set time (generally 60 seconds) following the administration of a neuromuscular (NM) blocking agent, rocuronium.
- Trial name
- NCT07435792
- Testing
- TetraGraph
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Nationwide Children's Hospital
Postoperative Residual Curarization, Neuromuscular Blockade
Comparison of Adductor Pollicis and Abductor Digiti Minimi Muscles (Thumb Vs. Fifth Digit) As Sites for Neuromuscular Monitoring with Electromyography
This study aims to evaluate the performance of the TetraGraph on two muscle groups: the adductor pollicis and the abductor digiti minimi. Theese muscles are located on the arms.
- Trial name
- NCT06691204
- Where
- 2 sites in Hungary
- Volunteers
- 46 people
- Sponsor
- Tamas Vegh, MD
Spine Surgery, Intraoperative Neurophysiological Monitoring
Low-Dose Rocuronium Maintenance During Spine Surgery With Intraoperative Neurophysiological Monitoring
This randomized controlled trial will compare two strategies for rocuronium use during general anesthesia for spine surgery with intraoperative neurophysiological monitoring.
- Conditions
- Spine Surgery, Intraoperative Neurophysiological Monitoring, Neuromuscular Blockade
- Trial name
- ROC-IONM (NCT07627750)
- Testing
- Low-Dose Rocuronium Maintenance, Rocuronium
- Where
- Vietnam
- Volunteers
- 62 people
- Sponsor
- Bach Mai Hospital
Nerve Conduction Study, Elective Surgery
Median Nerve Electromyography to Monitor Intraoperative Neuromuscular Function
The effect of muscle relaxants need to be followed during surgery and before waking up the patient, the anesthesiologist has to make sure that the effect of muscle relaxants is gone.
- Conditions
- Nerve Conduction Study, Elective Surgery, Neuromuscular Monitoring After Administration of Neuromuscular Blocking Agents in Different Types of Surgery
- Trial name
- NCT07571395
- Testing
- Electromyography
- Where
- Hungary
- Volunteers
- 45 people
- Sponsor
- Pongrácz Adrienn
Airway Management, Endotracheal Intubation
REMIfentanil (2 vs. 4 mcg/kg) Facilitated Intubation Without Neuromuscular Blockade Versus Succinylcholine and Rocuronium With Sugammadex for Endotracheal Intubation in Spine Surgery Requiring Motor Evoked Potential Monitoring
The purpose of this research is to compare four commonly used anesthesia medication strategies for placing a breathing tube in patients undergoing spine surgery that requires motor evoked potential (MEP) monitoring.
- Trial name
- REMI-MEP (NCT07835295)
- Testing
- Low-Dose Remifentanil, High-Dose Remifentanil, Succinylcholine
- Where
- United States
- Volunteers
- 316 people
- Sponsor
- Mayo Clinic