Clinical trials: Neuromuscular Disease Patients
CRPS Type I of the Upper Extremity, Neuropathy of the Median Nerve
Two Measures of Tactile Acuity in CRPS Type I Patients
This study aims to investigate whether two different measures of tactile acuity lead to comparable results in patients diagnosed with CRPS Type I of the upper extremity.
- Conditions
- CRPS Type I of the Upper Extremity, Neuropathy of the Median Nerve, Healthy Controls
- Trial name
- NCT01888783
- Testing
- Tactile acuity measured by 2PD and the GOT
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ruhr University of Bochum
Fibromyalgia
Effects of Two Different Applications in Fibromyalgia
The study aims to determine the effect of connective tissue massage and taping applications on the pain and depression complaints of fibromyalgia patients and to compare their impact on quality of life.
- Trial name
- NCT05897931
- Testing
- Connective tissue massage, Kinesio Tape Application
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Biruni University
Lumbar Spine Disease
Deep Neuromuscular Block on Postoperative Delirium in Lumbar Surgery
The effect of deep neuromuscular blockade (NMB) during spine surgery reduced postoperative pain and bleeding in recent studies. Therefore by reducing these two factors, which were the contributing factors for postoperative…
- Trial name
- NCT05453929
- Testing
- Rocuronium for deep NMB, Rocuronium for moderate NMB
- Where
- South Korea
- Volunteers
- 230 people
- Sponsor
- Korea University Guro Hospital
Acute Leukemia
Physical Fitness Impact of Early Physiotherapy Intervention With a Standardized Exercise Therapy Program in Adult Patients Receiving Intensive Induction Chemotherapy for Treatment of Acute Leukemia During Extended Hospitalization.
This study aimed to investigate the impact of Physical therapy in adult patients receiving intensive induction chemotherapy for the treatment of acute leukemia during prolonged hospitalization.
- Trial name
- KinHémo (NCT04899882)
- Testing
- KinHémo
- Where
- 4 sites in France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Angers
Vitamin D Deficiency, Sarcopenia
Effect of Vitamin D3 Supplementation on Muscle Mass in ICU Patient
A randomized double blind placebo control trial study will be conducted in critically ill patients with vitamin D deficiency. Investigator aimed to study the effect of oral vitamin D3 supplementation, compare to placebo, on…
- Conditions
- Vitamin D Deficiency, Sarcopenia, Critical Illness
- Trial name
- NCT02594579
- Testing
- Vitamin D3
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Refractory Cancer, CNS Tumors
A Study of Avutometinib for People With Solid Tumor Cancers
The purpose of this study is to find out whether avutometinib is a safe treatment for advanced or recurrent solid tumor cancers in children and young adults.
- Conditions
- Refractory Cancer, CNS Tumors, CNS Tumor, Adult, CNS Tumor, Childhood
- Trial name
- NCT06104488
- Testing
- Avutometinib
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Mesothelioma, Non Small Cell Lung Cancer
Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion
This is a Phase 1, open-label, multicenter, study of the safety, tolerability, PK, PD, and anti-tumor activity of MRTX1719 patients with advanced, unresectable or metastatic solid tumor malignancy with homozygous deletion of the…
- Conditions
- Mesothelioma, Non Small Cell Lung Cancer, Malignant Peripheral Nerve Sheath Tumors, Solid Tumor
- Trial name
- NCT05245500
- Testing
- MRTX1719
- Where
- 25 sites in United States
- Volunteers
- 336 people
- Sponsor
- Bristol-Myers Squibb
Fibromyalgia
Nurse Educational Intervention to Improve Symptoms in Fibromyalgia Patients
To improve self-care and therapy adherence by fibromyalgia (FM) patients through a nursing educational intervention. Historic diagnoses of subjects included terms such as "insane", "imaginary ill", "whiny"; as well, their…
- Trial name
- NCT05247411
- Testing
- Educational intervention
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Milano Bicocca
Amyotrophic Lateral Sclerosis, Neurodegenerative Disease
Satisfaction Survey for Amyotrophic Lateral Sclerosis (ALS) Patients Comparing Rooms With and Without Assistive Technology
The purpose of this study is : 1. To assess the ALS patient's satisfaction related to a hospital stay on the neurology floor of Hahnemann Hospital. 2.
- Conditions
- Amyotrophic Lateral Sclerosis, Neurodegenerative Disease, Motor Neuron Disease
- Trial name
- NCT00718107
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Drexel University College of Medicine
Lupus, Fibromyalgia (FM)
Helping Lupus Patients Manage Fibromyalgia Symptoms Through Emotional Awareness and Expression Therapy (EAET)
The goal of this clinical trial is to learn if a psychotherapy intervention works to relieve widespread pain in patients with lupus.
- Conditions
- Lupus, Fibromyalgia (FM), Chronic Widespread Pain
- Trial name
- EAET (NCT07282392)
- Testing
- Emotional Awareness and Expression Therapy (EAET)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Utah
Familial Amyloid Polyneuropathy, ATTR-PN
An Extension of Study Fx-005 Evaluating Long-Term Safety And Clinical Outcomes Of Fx-1006A In Patients With Transthyretin Amyloid Polyneuropathy
This study is designed to determine the long-term safety and tolerability of Fx-1006A as well as the effects of Fx-1006A on clinical outcomes in patients with ATTR-PN.
- Trial name
- NCT00791492
- Testing
- Fx-1006A
- Where
- 11 sites in Argentina, Brazil and 4 more
- Volunteers
- 86 people
- Sponsor
- Pfizer
Cancer, Pain
Oxycodone and Pregabalin for the Treatment of Oncological Neuropathic Pain
The aim of the study is to assess tolerability and activity of oxycodone and pregabalin in combination for the treatment of oncological neuropathic pain with two different strategies.
- Trial name
- NCT00637975
- Testing
- oxycodone, pregabalin
- Where
- 8 sites in Italy
- Volunteers
- 80 people
- Sponsor
- Associazione Progetto Oncologia UMAN.A
Fibromyalgia
Combined Behavioral and Analgesic Trial for Fibromyalgia
This is a randomized control study that involves a combination of a drug treatment, behavioral health, and placebo controls. Some participants will receive a medication approved by the Food and Drug Administration for treatment…
- Trial name
- COMBAT-FM (NCT01598753)
- Testing
- Tramadol, Cognitive Behavior Therapy for FM, Health Education
- Where
- 2 sites in United States
- Volunteers
- 134 people
- Sponsor
- University of Washington
Breast Carcinoma, Breast Cancer
Diffusion Tensor Imaging in Predicting Development of Chemotherapy Induced Peripheral Neuropathy in Patients With Breast Cancer (CIPN)
This pilot early phase I trial studies how well diffusion tensor imaging works in predicting development of chemotherapy induced peripheral neuropathy in patients with breast cancer.
- Conditions
- Breast Carcinoma, Breast Cancer, Neuropathy;Peripheral, Neuropathy
- Trial name
- CIPN (NCT03365895)
- Testing
- Diffusion Tensor Imaging, Laboratory Biomarker Analysis, Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Arizona
Neuromuscular Diseases, Hemiparesis
Validation Study of Posturology Platforms for Evaluating Postural Control of Hemiparetic and Neuro-muscular Patients
The instrumental evaluation of standing postural control by posturographic analysis supplements the clinical evaluation and, as such, is recommended by the French National Authority for Health (HAS 2007).
- Conditions
- Neuromuscular Diseases, Hemiparesis, Charcot-Marie-Tooth Disease
- Trial name
- KPLATES (NCT04283175)
- Testing
- Posturological examination on KPlates and AMTI platforms, Berg Balance Scale (BBS)
- Where
- France
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Amyotrophic Lateral Sclerosis
Phase III Trial of AMX0035 for Amyotrophic Lateral Sclerosis Treatment
The Phoenix Trial is a randomized double blind placebo controlled Phase III trial to evaluate the safety and efficacy of AMX0035 for treatment of ALS
- Trial name
- Phoenix (NCT05021536)
- Testing
- AMX0035
- Where
- 69 sites in United States, Belgium and 10 more
- Volunteers
- 664 people
- Sponsor
- Amylyx Pharmaceuticals Inc.
Cardiac Catheterization, Spasm
Topical Radial Artery Vasodilation
The aim of the study is to facilitate radial artery access for cardiac catheterization. The investigators hypothesize that topical nitroglycerin and lidocaine will reduce radial artery spasm.
- Trial name
- NCT01155167
- Testing
- Nitroglycerin and lidocaine
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of California, San Francisco
ALS - Amyotrophic Lateral Sclerosis
Comprehensive Biomarker Profiling of the IFN-α Pathway in Amyotrophic Lateral Sclerosis Patient Biofluids
ALS is characterized by significant genetic, clinical, and biological heterogeneity. The heritability of ALS is approximately 50%, and variants in more than 200 genes have been associated with the disease.
- Trial name
- NCT07260981
- Where
- Ireland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ulysses Neuroscience LTD
Sarcopenia, Lung Cancer
Assessment System of Sarcopenia in Lung Cancer Patients
1. To explore the diagnostic value of musculoskeletal cross-modal imaging assessment system of ultrasound combined with abdominal CT/MRI for sarcopenia in patients with lung cancer. 2.
- Conditions
- Sarcopenia, Lung Cancer, Ultrasound
- Trial name
- NCT06327594
- Testing
- ultrasound scan, CT/MRI scan
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- West China Hospital
Post-Stroke Spasticity, Spastic Equinovarus Foot
Efficacy of Focused Shock Wave Therapy Before and After Botulinum Toxin Injection in Patients With Post-Stroke Spastic Equinus/Equinovarus Foot: A Randomized Clinical Trial
Spastic equinovarus foot is the most common lower limb motor impairment after stroke and has a significant impact on gait, mobility, and quality of life.
- Trial name
- NCT07758322
- Testing
- Botulinum toxin type A, Focal Extracorporeal Shock Wave Therapy (ESWT)
- Where
- Spain
- Volunteers
- 69 people
- Sponsor
- María Belén Martínez Luna
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