Clinical trials: Neuromuscular Fatigue
Multiple Sclerosis, Amyotrophic Lateral Sclerosis
Polish Version Fatigue Severity Scale
Fatigue is one of main symptoms in multiple sclerosis, amyotrophic lateral sclerosis and other diseases with profound effect on quality of life and professional and social functioning.
- Conditions
- Multiple Sclerosis, Amyotrophic Lateral Sclerosis, Stroke, Ischemic
- Trial name
- NCT06668649
- Testing
- Testing with Questionnaires
- Where
- 2 sites in Poland
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Jakub Antczak
Hemodialysis Complication, Muscle Spasm
Hot and Cold Compress in Hemodialysis
Aims and objectives. To examine and compare the effects of hot and cold compresses administration on muscle cramps, fatigue, and comfort in hemodialysis (HD) patients. Background.
- Conditions
- Hemodialysis Complication, Muscle Spasm, Fatigue
- Trial name
- NCT04681521
- Testing
- Hot and Cold compress, nursing interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Muscle Fatigue
Post-Fatigue Vibration: Impact on Grip and Reaction Time
This study aims to investigate the acute effects of local vibration applied after induced fatigue of the wrist flexor muscles on grip strength and upper extremity reaction time.
- Trial name
- NCT06949566
- Testing
- 100 Hz Local Vibration, 50 Hz Local Vibration
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Bitlis Eren University
Neuromuscular Disease, Inspiratory Muscle Training
Manual Therapy and Inspiratory Muscle Training in Neuromuscular Disease
The benefits of inspiratory muscle training (IMT) have been reported in neuromuscular diseases. However, its effects are limited.
- Conditions
- Neuromuscular Disease, Inspiratory Muscle Training, Manual Therapy
- Trial name
- NCT07416929
- Testing
- inspiratory muscle training, Manual therapy, Conventional physiotherapy programme
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people
- Sponsor
- Istinye University
Muscle Fatigue
Characterization of Hamstring and Quadriceps Neuromuscular Fatigue After Consecutive Soccer Trainings in Soccer Players
This is a monocentric study assessing hamstring and quadriceps neuromuscular fatigue after 3 consecutive soccer trainings. The purpose of this study was: 1.
- Trial name
- QIF2 (NCT07861269)
- Testing
- a simulated soccer training
- Volunteers
- 20 people
- Sponsor
- University Hospital, Strasbourg, France
Bodily Distress Syndrome, Irritable Bowel
Health Care Use and Costs of Functional Somatic Disorders
The goal of this observational case-control study is to learn about direct healthcare use and costs of functional somatic disorders.
- Conditions
- Bodily Distress Syndrome, Irritable Bowel, Fibromyalgia, Chronic Widespread Pain
- Trial name
- NCT05811663
- Where
- Denmark
- Volunteers
- 9,656 people
- Sponsor
- Aarhus University Hospital
Obesity, Arterial Stiffness
Phase II Study of Neuromuscular Electrical Multisite System on Cardiovascular Effects in Severe Obese Patients
The study was designed to test the following hypotheses: In patients with severe obesity, a multisite electrostimulation session (m-NMES) will induce higher changes in metabolic, inflammatory and cardiovascular parameters and…
- Conditions
- Obesity, Arterial Stiffness, Electrical Stimulation, Training
- Trial name
- StimobII (NCT01820598)
- Testing
- Multisite NMES training during 6 weeks
- Where
- France
- Volunteers
- 30 people
- Sponsor
- AGIR à Dom
Chronic Pain, Fibromyalgia
Developing an Activity Pacing Framework: Feasibility and Acceptability
This study explores whether it is feasible to use a newly developed activity pacing framework to standardise how activity pacing is instructed by healthcare professionals in rehabilitation programmes for patients with chronic…
- Conditions
- Chronic Pain, Fibromyalgia, Chronic Fatigue Syndrome, Chronic Low Back Pain
- Trial name
- NCT03497585
- Testing
- Activity pacing framework
- Where
- United Kingdom
- Volunteers
- 112 people
- Sponsor
- Pennine Acute Hospitals NHS Trust
Fibromyalgia
Translation and Psychometric Properties of the Fatigue Severity Scale in Patients With Fibromyalgia
The study will employ a Cross-Sectional Validation Study design. The study will be conducted at the Department of Physical Therapy, University of Lahore Teaching Hospital, located on Defence Road, Lahore.
- Trial name
- NCT06031207
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- University of Lahore
Carpal Tunnel Syndrome (CTS)
Changes in Sleep, Fatigue, Kinesiophobia, and Upper Extremity Function After Carpal Tunnel Release
Carpal tunnel syndrome can cause hand pain, numbness, weakness, sleep disturbance, fatigue, fear of movement, and difficulty performing daily activities.
- Trial name
- CTS-RECOVER (NCT07806071)
- Testing
- Carpal Tunnel Release Surgery
- Volunteers
- 100 people
- Sponsor
- Istanbul Medipol University Hospital
Juvenile Idiopathic Arthritis, Rheumatic Diseases
Low-energy Laser Applications in Patients With Juvenile Idiopathic Arthritis
This study endeavored to evaluate the auxiliary effect of low-energy laser therapy (LLT) on pain, muscle performance, fatigue, and functional ability in children with juvenile idiopathic arthritis (JIA).
- Conditions
- Juvenile Idiopathic Arthritis, Rheumatic Diseases, Chronic Knee Pain, Fatigue
- Trial name
- NCT05031104
- Testing
- Physical Exercise, Physical Exercise plus Low-energy Laser Therapy
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- Cairo University
Myasthenia Gravis
Prevalence and Impact of Fatigue in Myasthenic Patients Followed At Clermont-Ferrand University Hospital - "My" Asthenia
After identifying myasthenic patients meeting the inclusion criteria, telephone contact with patients to suggest that they participate in the study by responding to various questionnaires composed of validated scales used in…
- Trial name
- NCT06877403
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Chronic Fatigue Syndrome, Behavioral Therapy Targeted to Sleep Problems
Behavioral Insomnia Therapy With Chronic Fatigue Syndrome
The purpose of this study is to determine how best to manage the sleep problems of people with Chronic Fatigue Syndrome. This study is being conducted to determine how improvements in sleep affect other Chronic Fatigue symptoms…
- Trial name
- NCT00540254
- Testing
- Cognitive Behavioral Therapy, Usual Care for Chronic Fatigue Syndrome (Active Control Group)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Duke University
SARS-CoV-2 Acute Respiratory Disease, Myalgic Encephalomyelitis
Does a Technology Enabled Multi-disciplinary Team-based Care Model for the Management of Long COVID and Other Fatiguing Illnesses Improve Clinical Care of Patients and Represent a Sustainable Approach Within a Federally Qualified Health Center?
The primary objective of the present research is to determine the effectiveness of Family Health Center of San Diego's Long COVID and Fatiguing Illness Recovery Program (LC\&FIRP) on clinician- and patient-level outcomes.
- Conditions
- SARS-CoV-2 Acute Respiratory Disease, Myalgic Encephalomyelitis, Chronic Fatigue Syndrome, Post-acute Sequelae of SARS-COV-2 Infection
- Trial name
- LC&FIRP (NCT05167227)
- Testing
- Extension for Community Healthcare Outcomes
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Family Health Centers of San Diego
Duchenne Muscular Dystrophy, Duchenne Disease
Evaluating VM100 Nutritional Supplement for Improving Quality of Life in Duchenne Muscular Dystrophy Patients
This pilot study will investigate the potential efficacy of VM100, a nutritional supplement specifically formulated for patients with DMD, on quality of life and physical symptoms.
- Conditions
- Duchenne Muscular Dystrophy, Duchenne Disease, Muscular Dystrophy in Children, DMD
- Trial name
- NCT07766980
- Testing
- VM100 Nutritional Supplement
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Florida
Myalgic Encephalomyelitis
Effect of CoQ10 Plus Selenium Supplementation on Clinical Outcomes and Biochemical Markers in ME/CFS (CoSeME Study)
In recent years, it has been suggested that nutritional deficiencies may be of causal relevance in individuals with ME/CFS. These include deficiencies of vitamins and trace elements.
- Trial name
- CoSeME (NCT05128292)
- Testing
- CoQ10 plus Selenium
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Long COVID, Postural Orthostatic Tachycardia Syndrome
The Long COVID-19 Wearable Device Study
To further characterize Long COVID-19 by collecting data from individuals who already own wearable devices or are provided with a wearable device along with basic and enhanced educational materials to determine if both can…
- Conditions
- Long COVID, Postural Orthostatic Tachycardia Syndrome, Dysautonomia, Myalgic Encephalomyelitis
- Trial name
- NCT05741112
- Testing
- Wearable device
- Where
- United States
- Volunteers
- 100,500 people
- Sponsor
- Scripps Translational Science Institute
Sprint Training
Recovery Kinetics After Different Sprint Training Protocols (STRecovery)
Speed is one of the most important physical capacities for many sports, especially those that include speed and power as a major element, and plays a major role on performance.
- Trial name
- STRecovery (NCT04766411)
- Testing
- Unresisted sprint training, Resisted sprint training with load equal to 10% of body weight, Resisted sprint training with load equal to 20% of body weight
- Where
- Greece
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Fibromyalgia
Mechanism of Fatigue in Fibromyalgia and Cortical Motor Neuron Dysfunction
The goal of this study is to test whether cortical motor neuron dysfunction plays a role in the pathogenesis of fatigue in fibromyalgia patients.
- Trial name
- NCT06778681
- Testing
- Cheer
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Diaphragmatic Dysfunction, Muscle Weakness
Recovery of Diaphragmatic Function After Neuromuscular Blockade and Sugammadex
The effect of neuromuscular blocking agents (NMBA, e.g. rocuronium) on respiratory muscle activity is well known. However, since the availability of sugammadex, to our knowledge, no study has been conducted to evaluate the effect…
- Conditions
- Diaphragmatic Dysfunction, Muscle Weakness, Muscle Fatigue
- Trial name
- SUDIA (NCT01962298)
- Testing
- sugammadex 2mg/kg, neostigmine, sugammadex 4mg/kg
- Where
- Belgium
- Volunteers
- 75 people
- Sponsor
- University Hospital, Antwerp