Clinical trials: Neuromuscular Physiology
Muscle Weakness, Syndrome; Institutionalization
Respiratory Muscle Training in Institutionalized Elderly Population
The global loss of muscle mass and strength associated with aging is a cause of functional impairment and disability, particularly in the frail elderly.
- Conditions
- Muscle Weakness, Syndrome; Institutionalization, Other Diagnoses, Comorbidities, and Complications
- Trial name
- NCT01624272
- Testing
- Threshold® Inspiratory Muscle Trainer (Respironics® Health Scan Inc. Cedar Grove, NJ, USA)., Yoga Pranayama breathing exercises
- Where
- 3 sites in Spain
- Volunteers
- 71 people
- Sponsor
- University of Valencia
Diplegic Cerebral Palsy
"Immediate Effect of DAFO on Gross Motor Function and Balance in Diplegic Cerebral Palsy
" Study will investigate the immediate effect of DAFO usage on balance and gross motor functions in individuals with spastic diplegic cerebral palsy.
- Trial name
- NCT06343688
- Testing
- "Assessment of Balance and Lower Extremity Gross Motor Function with and without DAFO"
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Neonatal Brachial Plexus Palsy
Does Wearing Tetra-Grip Improve Arm Function in Children Diagnosed With Neonatal Brachial Plexus Palsy?
This study evaluates the effect of wearing a tetra-grip on the affected arm of children with neonatal brachial plexus palsy. Half of the participants will have tetra-grip applied to the arm, while the other half will not have it…
- Trial name
- NCT03647761
- Testing
- Tetra-grip
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Texas Southwestern Medical Center
Acromioclavicular Joint Injury, Acromioclavicular Joint Dislocation
Contralateral Resistance Training During Immobilization in Patients With Acromioclavicular Joint Injury
This randomized controlled trial aims to compare the effects of contralateral eccentric and concentric resistance training performed during the immobilization period following acromioclavicular joint injury.
- Trial name
- CROSS-ACD (NCT07628361)
- Testing
- Contralateral Eccentric Resistance Training, Contralateral Concentric Resistance Training
- Where
- Chile
- Volunteers
- 16 people
- Sponsor
- Universidad Nacional Andres Bello
Muscle Damage, Inflammation
Protein and Recovery From Exercise-induced Muscle Damage
Intense, eccentric resistance exercise causes muscle damage, soreness, inflammation, and a loss of muscle function. Protein-amino acid supplementation before, during, and following damaging resistance exercise may reduce muscle…
- Trial name
- NCT02034721
- Testing
- Protein supplement
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Muscle Weakness
The Effect of Exercise on Muscle, Function and Cost in VA Nursing Home Residents
Veterans are admitted to Veterans Health Administration (VA) Nursing Homes (NH) because impairment in their ability to perform activities of daily living (ADL) overwhelms their support system (family/friends) in the community.
- Trial name
- NCT00105807
- Testing
- participation in low intensity exercise, participation in art and music activities
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- US Department of Veterans Affairs
Heart Failure With Reduced Ejection Fraction
Neuromuscular Fatigability in Individuals With Heart Failure
Brief summary The aims of this project are to 1) characterise muscle fatigue in individuals with chronic heart failure during exercise involving a smaller and larger muscle mass (Part I), 2) to determine the effect of nitrate…
- Trial name
- NCT06551012
- Testing
- Nitrate-rich beetroot juice, Beetroot juice with nitrate extracted
- Volunteers
- 28 people
- Sponsor
- Newcastle University
Smoking Dependence, Smoking Among Youth
Efficacy of Diaphragmatic Proprioceptive Neuromuscular Facilitation on Functional Capacity and Pulmonary Function in Heavy Twenties Smokers
Although research on the health risks of e-cigarettes is still limited, there is increasing evidence of debilitating lung disease and general immune dysfunction from e-cigarettes, leading to various infections.
- Trial name
- NCT07003893
- Testing
- Diaphragmatic Proprioceptive Neuromuscular Facilitation + Aerobic exercises
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Zaytoonah University of Jordan
Post Menopausal, Resistance Exercise
Feasibility of Lower-Body EMS Resistance Training in Postmenopausal Women
This pilot randomized controlled trial evaluates whether combining lower-body electrical muscle stimulation (EMS) with resistance training is feasible and beneficial for physically inactive postmenopausal women, who experience…
- Conditions
- Post Menopausal, Resistance Exercise, Body Composition, Autonomic Function
- Trial name
- LB-EMS-Pilot (NCT07628790)
- Testing
- Lower-Body EMS combined with Resistance Training, Resistance Training
- Where
- South Korea
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Seoul National University
Alzheimer Disease, Sarcopenia
Silkworm Pupa Powder Improves Alzheimer's Disease
The goal of this clinical trial is to learn if silkworm pupa powder works to treat Alzheimer's disease in patients. It will also learn about the safety of silkworm pupa powder, and its effect on patients' nutritional and frailty…
- Conditions
- Alzheimer Disease, Sarcopenia, Asthenia, Frailty
- Trial name
- NCT07638449
- Testing
- Silkworm pupa powder
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhejiang Provincial Tongde Hospital
Healthy
Strength Training and Muscle Lipids
The purpose of this study is examine the effects of 8 weeks (3 days/week) of resistance exercise training in children 8 to 10 years of age on muscle strength and power, motor unit activation, and lipid profiles of the vastus…
- Trial name
- Strength-Lip (NCT06480747)
- Testing
- Resistance exercise training
- Where
- 4 sites in United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Healthy, Healthy Participants
Acute Effects of Structured Exercise and Static Stretching on Vascular Function, Neuromuscular Performance, and Metabolic Regulation in Adults
This experimental study investigates the acute cardiovascular and vascular responses to a single session of resistance training, with and without additional static stretching, compared with a resting control condition.
- Conditions
- Healthy, Healthy Participants, Healthy Subjects (HS), Resistance Training Adaptation
- Trial name
- NCT07364149
- Testing
- Resistance Training, Resistance training + Static Stretching
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Fibromyalgia
Development of Treatments Aiming at Improvement of Function in Patients With Chronic Widespread Pain
The study aims to evaluate the effects of adding supervised exercise in supplement to an educational self-management program, and to determine which subgroups would gain effects of the treatment.
- Trial name
- NCT00545649
- Testing
- Exercise and education, Education
- Where
- 3 sites in Sweden
- Volunteers
- 164 people
- Sponsor
- Göteborg University
Sarcopenia
Carnitine Supplementation and Skeletal Muscle Function
Research project objectives The primary aim of the current research project is to use carnitine supplementation as the anti-inflammatory intervention for exploring the relationship between inflammation and associated with aging…
- Trial name
- NCT02692235
- Testing
- carnitine
- Where
- Poland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Hydroxymethylglutaryl-CoA Reductase Inhibitors, Muscular Diseases
The Effect of Statin Medications on Muscle Performance (The STOMP Study)
Statins are a group of medications that are used to lower cholesterol levels. Although serious side effects are rare, some people taking statins experience muscle pain or weakness.
- Trial name
- STOMP (NCT00609063)
- Testing
- Atorvastatin
- Where
- 3 sites in United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Sarcopenia
Effect of Essential Aminoacid Supplementation and Exercise on Skeletal Muscle Function in Hemodialysis Patients
Sarcopenia can be easily observed in patients with hemodialysis. However, there were few studies on the precise concept and diagnostic criteria for sarcopenia in patients with hemodialysis.
- Trial name
- NCT05884138
- Testing
- exercise and nutritional support
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Chungnam National University Hospital
Peripheral Neuropathic Pain
Gabapentin and Pregabalin Effects on Inflammation and Cardiac Function in Peripheral Neuropathic Pain
This prospective, controlled, observational cohort study will evaluate short-term changes in inflammatory biomarkers and subclinical cardiac function in adults with peripheral neuropathic pain who are prescribed gabapentin or…
- Trial name
- NCT07755514
- Testing
- Gabapentin, Pregabalin
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Giresun University
Rotator Cuff Tears
Central Neuromuscular Dysfunction, Functionality, Psychological Status and Rotator Cuff Surgery
Considering the fact that The problems experienced by the patients are not only physiological but also psychological and social. Unfortunately, there is no sufficient study focus on all these concepts.
- Trial name
- NCT05566470
- Testing
- Assessment of Central Neuromuscular Dysfunction, Shoulder Physical Functionality and Psychological Factors
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dietary Supplements: Beetroot Juice Acute Supplementation, Dietary Supplement: Placebo Acute Supplementation
Acute Effects of Beetroot Juice Ingestion on Cognitive Function and Neuromuscular Performance in Elite Female Taekwondo Athletes
Beetroot juice is a good source of nitrate (NO3-), which is a precursor of nitric oxide (NO) through the NO3- to nitrite (NO2-) to NO pathway (Lundberg et al., 2008).
- Trial name
- BEET_TAEKWONDO (NCT06675305)
- Testing
- Beetroot juice (James White, UK)
- Where
- Spain
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Universidad Pontificia Comillas
Core Strength, Knee Stability
Influence of Abdominal Muscle Function on Knee Stability for Injury Prevention
The goal of this clinical trial is to learn whether an 8-week core stabilization training program can improve abdominal strength and knee stability in physically active women aged 18 to 35.
- Trial name
- NCT07499973
- Testing
- Core Stabilization Training Program
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- European University of Madrid