Clinical trials: Neuropathic Pain, open to volunteers
Pain (Visceral, Somatic, or Neuropathic), Anxiety Acute
The Effect of Sound-Based Interventions on Pain and Anxiety in Pediatric Patients
This study is a prospective, three-arm, single-blind, randomized controlled clinical trial designed to evaluate the effectiveness of non-pharmacological sound-based interventions on pain and anxiety in pediatric patients.
- Trial name
- PED-SOUND-PAIN (NCT07727109)
- Testing
- white noise, pink noise
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Tokat Gaziosmanpasa University
Peripheral Nerve Stimulation, Chronic Neuropathic Pain
Mechanisms of Stimulation for Pain Alleviation
This is a mechanistic randomized controlled trial of patients with chronic neuropathic pain (CNP) in the upper extremities, lower back, pelvis, and lower extremities, randomized to conventional medical management (CMM) or…
- Conditions
- Peripheral Nerve Stimulation, Chronic Neuropathic Pain, Chronic Neuropathic Pain (Below the Shoulders)
- Trial name
- M-SPA (NCT06741579)
- Testing
- Peripheral Nerve Stimulation, Conventional Care Regimen
- Where
- 2 sites in United States
- Volunteers
- 148 people
- Sponsor
- Stanford University
Neuropathic Pain, Postherpetic Neuralgia
Simultaneous Engagement of Networks for Alleviating Pain (SENAP)
This trial is investigating the acceptability and efficacy of PFM-guided cortical stimulation for the treatment of central neuropathic pain.
- Trial name
- NCT07057206
- Testing
- PFM-guided cortical stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Minnesota
Diabetic Peripheral Neuropathic Pain
Evaluation of Efficacy and Safety of Suzetrigine (SUZ) for Pain Associated With Diabetic Peripheral Neuropathy
The purpose of this study is to evaluate the efficacy, safety, and tolerability of Suzetrigine in participants with pain associated with diabetic peripheral neuropathy (DPN).
- Trial name
- NCT07231419
- Testing
- Suzetrigine
- Where
- 75 sites in United States
- Volunteers
- 734 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Diabetic Neuropathy, Neuropathic Pain
Extended-release Pregabalin for the Treatment of Neuropathic Pain in Patients With Diabetic Peripheral Neuropathy and Postherpetic Neuralgia
Extended-release Pregabalin for the Treatment of Neuropathic Pain in Patients With Diabetic Peripheral Neuropathy and Postherpetic Neuralgia
- Conditions
- Diabetic Neuropathy, Neuropathic Pain, Neuralgia, Postherpetic
- Trial name
- PRISE (NCT07712913)
- Testing
- Experimental: Pregabalin XR, Comparator: Dorene Tabs
- Where
- 15 sites in Brazil
- Volunteers
- 348 people
- Sponsor
- Brainfarma Industria Química e Farmacêutica S/A
Neuromyelitis Optica Spectrum Disorders (NMOSD), Neuropathic Pain
Crisugabalin in NMOSD Neuropathic Pain: A Randomized, Double-Blind, Placebo-Controlled Exploratory Trial
This study is a multicenter, prospective, randomized, double-blind, placebo-controlled exploratory investigation conducted in China.
- Trial name
- TERMINATOR (NCT07699770)
- Testing
- Crisugabalin
- Where
- 10 sites in China
- Volunteers
- 110 people
- Sponsor
- Tang-Du Hospital
Spinal Cord Injuries, Neuropathic Pain
Novel Soluble Epoxide Hydrolase Inhibitor for Neuropathic Pain in Patients With Spinal Cord Injury
The goal of this clinical trial is to evaluate safety and tolerability of multiple oral doses of EC5026 in male and female patients with neuropathic pain due to traumatic or non-traumatic (degenerative) spinal cord injury.
- Conditions
- Spinal Cord Injuries, Neuropathic Pain, Degenerative Disc Disease, Spinal Stenosis
- Trial name
- NCT06438471
- Testing
- EC5026 oral tablet
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- EicOsis Human Health Inc.
Diabetic Neuropathic Pain
Effectiveness of Pain Neuroscience Education Along With Neural Mobilization Versus Neural Mobilization Alone on Pain, Functional Disability And Quality of Life In Patients With Diabetic Neuropathic Pain
This is a randomized controlled trial aims to evaluate the comparative effect of Pain Neuroscience Education combined with neural mobilization versus neural mobilization alone in patients with diabetic neuropathic pain.
- Trial name
- NCT07695181
- Testing
- Pain Neurosciences Education + Neural Mobilization
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Ibadat International University, Islamabad
Chronic Pain, Pain Management
PREDICT-DOLOR VE: Validation of a Structured Triage Protocol for Chronic Pain
PREDICT-DOLOR VE is a structured clinical triage protocol for chronic pain that uses five internationally validated pain assessment instruments to help healthcare providers determine the appropriate level of care for patients…
- Conditions
- Chronic Pain, Pain Management, Neuropathic Pain
- Trial name
- PREDICT-VE (NCT07696676)
- Testing
- PREDICT-DOLOR VE
- Volunteers
- 120 people
- Sponsor
- Universidad Central de Venezuela
Osteoporotic Vertebral Fracture, Neuropathic Pain
Osteoporotic Fracture and Lidocaine Plaster 5% for Neuropathic Pain preventioN
Osteoporotic vertebral fractures may lead to chronic pain with a neuropathic component, which is often underdiagnosed and undertreated in older adults.
- Trial name
- FLYNN (NCT07691359)
- Testing
- Lidocaine 5% medicated plaster
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Clermont-Ferrand
Diabetic Peripheral Neuropathic Pain
A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Diabetic Peripheral Neuropathic Pain
The purpose of this study is to test the safety and efficacy of study drug LY4065967 for the treatment of diabetic peripheral neuropathic pain (DPNP).
- Trial name
- NP07 (NCT07285018)
- Testing
- LY4065967
- Where
- 37 sites in United States, Puerto Rico
- Volunteers
- 150 people
- Sponsor
- Eli Lilly and Company
Chronic Post-surgical Pain, Postoperative Pain After Thoracic Surgery
Prevalence and Risk Factors for Chronic Post-Surgical Pain Following Video-Assisted Thoracic Surgery : The EVATHO Prospective Bicentric Cohort Study.
Chronic post-surgical pain (CPSP) remains a common complication after thoracic surgery and may significantly impair patients' quality of life.
- Conditions
- Chronic Post-surgical Pain, Postoperative Pain After Thoracic Surgery, Neuropathic Pain, Thoracic Surgical Procedures
- Trial name
- EVATHO (NCT07687082)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Rectal Surgery, Pain (Visceral, Somatic, or Neuropathic)
Post Operative Pain and Vagal Stimulation
Anorectal surgery is a type of surgery that can cause anal pain, particularly in the context of hemorrhoid surgery or anal fissure surgery. Generally, the period of discomfort related to the pain lasts about two weeks.
- Conditions
- Rectal Surgery, Pain (Visceral, Somatic, or Neuropathic), Vagal Nerve Stimulation
- Trial name
- VAGANAL (NCT07659314)
- Testing
- Experimental arm, Control arm
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Angers
Neuropathic Pain
Study of the Location of Motor Cortical Stimulation Electrodes in Chronic Neuropathic Refractory Patients
Cortical stimulation has been used since 1991 to treat neuropathic pain. However, the underlying mechanisms are still incompletely understood and under-studied.
- Trial name
- NCT06216717
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Neuropathic Pain, Neuropathic Pain Diagnostic Questionnaire (DN4) ≥ 4
Hematological Indices and Sympathetic Block Response in Neuropathic Pain
This prospective observational study aims to evaluate the relationship between hematological inflammatory indices and clinical treatment response in patients with neuropathic pain undergoing sympathetic nerve block procedures as…
- Trial name
- HINSPAIN (NCT07596823)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara City Hospital Bilkent
Neuropathic Pain
The Prevalence of Neuropathic Pain Pathophysiology Associated With Ankle Fracture
This application addresses the Peer Reviewed Medical Research Program Investigator-Initiated Research Award FY21 W81XWH-22-CPMRP-IIRA area of Chronic Pain Management Research Program- The investigators will utilize subjects who…
- Trial name
- AFNP (NCT06420141)
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Indiana University
Spinal Cord Injuries, Neuropathic Pain
Repetitive Transcranial Magnetic Stimulation Therapy in Spinal Cord Injury Related Neuropathic Pain
The aim of our study is to investigate the effect of different protocols of high-frequency Repetitive Transcranial Magnetic Stimulation (rTMS) therapy added to the rehabilitation program on neuropathic pain,depression, quality of…
- Trial name
- NCT06726954
- Testing
- High-frequency real-time rTMS DLPF cortex protocol, High-frequency real-time rTMS M1 motor cortex protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Afyonkarahisar Health Sciences University
Dental Neuralgia, Neuropathic Dental Pain
Neuropathic Dental Pain & DBS
This prospective observational study will evaluate pain outcomes in patients with neuropathic dental pain (Atypical Odontalgia/Phantom Tooth Pain) who undergo directional deep brain stimulation (DBS).
- Trial name
- NCT07671950
- Testing
- Directional Deep Brain Stimulation
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- University of British Columbia
Gonarthrosis, Neuropathic Pain, Nociceptive Pain
Functional Brain MRI to Understand Pain Phenotypes in Knee Osteoarthritis
Some people with knee osteoarthritis (gonarthrosis) experience pain differently. In some, the pain is described as "nociceptive" (directly related to the joint), while in others it has "neuropathic" characteristics (related to…
- Trial name
- INDIGO (NCT07668674)
- Testing
- blood sampling, Resting-state functional MRI
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Clermont-Ferrand
Pain (Visceral, Somatic, or Neuropathic), Women of Reproductive Age
Virtual Menstrual Pain Approaches in Females
This research study is testing two self-care approaches that may help prevent or reduce period pain in young females with recurrent painful menstrual cramps.
- Conditions
- Pain (Visceral, Somatic, or Neuropathic), Women of Reproductive Age, Mental Disorder, Digital Health
- Trial name
- AABQ (NCT07497711)
- Testing
- Virtual Auricular Acupressure, Virtual Baduanjin Qigong Exercise, Self Education
- Where
- Singapore
- Volunteers
- 145 people
- Sponsor
- Nanyang Technological University