Clinical trials: Neuropathy (Disorder)
HIV Infections, Neuropathy
Epoetin Alfa for HIV-Associated Neuropathy Trial
The purpose of this study is to evaluate the effect of epoetin alfa on HIV-associated neuropathy by measuring changes in nerve fiber density and pain ratings.
- Trial name
- NCT00528593
- Testing
- epoetin alfa
- Sponsor
- Washington University School of Medicine
Low Back Pain, Mechanical, Piriformis Syndrome
Strain-Counterstrain Treatment of Piriformis Pain
The purpose of this investigator-initiated study is to provide an efficient and non-invasive treatment option for pain caused by the piriformis muscle.
- Conditions
- Low Back Pain, Mechanical, Piriformis Syndrome, Somatic Dysfunction of Sacral Region (Finding)
- Trial name
- NCT05023005
- Testing
- Strain-Counterstrain treatment of piriformis muscle
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Neuromuscular Transmission Disorder, Diabetes Mellitus, Type 2
Effect of Type II Diabetes Mellitus With Neuropathy on the Clinical Use of Rocuronium
International Diabetes Federation estimates that there are now 415 million adults aged 20-79 with diabetes mellitus worldwide. By 2040 this will rise to 640 million.
- Trial name
- NCT03737942
- Testing
- monitoring of neuromuscular function
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Diabetic Neuropathy, Painful
Study to Assess Safety and Efficacy of Engensis in Painful Diabetic Peripheral Neuropathy
The purpose of this study is to evaluate the efficacy and safety of intramuscular administration of Engensis on pain in participants with painful diabetic peripheral neuropathy in the feet and lower legs, as compared to Placebo…
- Trial name
- REGAiN-1A (NCT04469270)
- Testing
- Engensis
- Where
- 16 sites in United States
- Volunteers
- 162 people
- Sponsor
- Helixmith Co., Ltd.
Carpal Tunnel Syndrome
High-Intensity Laser Therapy in Carpal Tunnel Syndrome: Clinical, Sonographic, and Electrophysiological Outcomes
Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy of the upper extremity and is characterized by pain, paresthesia, and functional impairment resulting from increased pressure within the carpal tunnel.
- Trial name
- NCT07414069
- Testing
- High-Intensity Laser Therapy (HILT)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara City Hospital Bilkent
Carpal Tunnel Syndrome
Clinical Validation of a Decompression Prototype Splint for Patients With Carpal Tunel Syndrome
A multicentric randomized controlled trial has been designed to study the effects of a decompression prototype splint on symptoms, functional capacity and nerve conduction studies in patients with carpal tunnel syndrome.
- Trial name
- NCT04043780
- Testing
- Decompression prototype splint for carpal tunnel syndrome, Standard splint for carpal tunnel syndrome
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Universidad de Zaragoza
Peripheral Neuropathy, HIV Infections
Open Label Safety And Efficacy Study Of Pregabalin In Subjects With Nerve Pain Asociated With Human Immunodeficiency Virus (HIV) Neuropathy
To evaluate the safety and efficacy of pregabalin in reducing neuropathic pain associated with HIV neuropathy
- Trial name
- NCT00264875
- Testing
- pregabalin
- Where
- 37 sites in United States, Puerto Rico
- Volunteers
- 220 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Limb Ischemia, Diabetic Foot
Safety and Efficacy of Allogeneic Adipose Tissue Mesenchymal Stem Cells in Diabetic Patients With Critical Limb Ischemia
Phase II national, multicenter, double-blind, randomized, placebo-controlled, phase-3 clinical trial of 3 parallel groups.
- Trial name
- NCT04466007
- Testing
- High dose allogeneic mesenchymal stromal cells, Low dose allogeneic mesenchymal stromal cells
- Where
- 10 sites in Spain
- Volunteers
- 90 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Sciatica, Lumbar Radiculopathy
Brain Mechanisms Supporting Cannabis-induced Pain Relief
Chronic low back pain is a common and disabling condition that affects millions of people in the United States. Many people with chronic low back pain do not get enough relief from current treatments.
- Conditions
- Sciatica, Lumbar Radiculopathy, Lower Back Pain, Degenerative Disc Disease
- Trial name
- NCT04982965
- Testing
- Active Cannabis
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Diabetes, Diabetes Complications
Pressure-Sensing Insoles in the Neuropathic Ulcer Treatment Pathway
Diabetic foot ulceration (DFU) is a common complication with a 25% lifetime risk in patients with diabetes. While most of these ulcers can be treated successfully on an outpatient basis, some will persist and become infected.
- Conditions
- Diabetes, Diabetes Complications, Neuropathy, Peripheral Neuropathy
- Trial name
- PINUP (NCT02586519)
- Testing
- SurroSense Rx System
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- University of Calgary
Diabete Mellitus, Diabete Type 2
A Pilot Study of the Effectiveness of Foot-Ankle and Walking Exercises in Patients With Diabetes Mellitus
This pilot feasibility and exploratory study, conducted to prepare for a definitive Randomized Controlled Trial (RCT), compares a structured foot-ankle exercise program with a walking exercise program in adults with Diabetes…
- Conditions
- Diabete Mellitus, Diabete Type 2, Diabetic Peripheral Neuropathy, Diabetic Foot
- Trial name
- NCT07270328
- Testing
- Foot-ankle exercise group, Walking exercise group, Control group
- Where
- 3 sites in Indonesia
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Efficacy and Safety Study of I10E in Treatment of Patients With CIDP
Primary objective: To assess the efficacy of I10E in improving the disability of patients with CIDP. Secondary objective: To assess the safety of I10E in patients with CIDP.
- Trial name
- PRISM (NCT02293460)
- Testing
- I10E
- Where
- 33 sites in France, Italy and 4 more
- Volunteers
- 44 people
- Sponsor
- Laboratoire français de Fractionnement et de Biotechnologies
Carpal Tunnel Syndrome
Efficacy of Extracorporeal Shock Wave Therapy on Carpal Tunnel Syndrome Post Mastectomy Lymphedema
Sixty eight female patients who had symptoms of carpal tunnel syndromesuch as wrist pain or numbness and paraesthesia and had lymphedema of an upper extremity.Their ages will be ranged from 40 to 60 years.
- Trial name
- NCT06131515
- Testing
- extra corporeal shock wave therapy device
- Where
- 2 sites in Egypt
- Volunteers
- 68 people
- Sponsor
- Cairo University
Carpal Tunnel Syndrome
Gabapentin for Carpal Tunnel Syndrome
The purpose of this study is to determine whether gabapentin is safe and effective in the treatment of carpal tunnel syndrome (CTS).
- Trial name
- NCT00137735
- Testing
- Gabapentin
- Where
- 2 sites in Hong Kong
- Volunteers
- 150 people
- Sponsor
- Chinese University of Hong Kong
Breast Cancer Female, Breast Cancer Patients
Effect of Pentoxifylline on Preventing Chemotherapy-induced Toxicities in Patients With Breast Cancer
This clinical trial is a randomized clinical trial that aims to assess the usefulness of adding pentoxifylline to the neoadjuvant chemotherapy treatment protocol of doxorubicin/cyclophosphamide fllowed by taxane for breast cancer…
- Conditions
- Breast Cancer Female, Breast Cancer Patients, Neoadjuvant Therapy, Doxorubicin
- Trial name
- NCT06186700
- Testing
- Pentoxifylline 400mg plus chemotherapy, Chemotherapy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Foot Ulcer, Diabetic
A Study to Assess the Effect of Topical Recombinant Human Vascular Endothelial Growth Factor for Induction of Healing of Diabetic Foot Ulcers
This is a Phase II, double-blind, randomized, placebo-controlled study to evaluate the safety and efficacy of three different doses of topically applied telbermin in subjects ≥ 18 years old with diabetic foot ulcers.
- Trial name
- NCT00351767
- Testing
- telbermin
- Volunteers
- 170 people
- Sponsor
- Genentech, Inc.
Type 1 Diabetes, Sleep Apnea Syndrome
Sleep Apnea in Type 1 Diabetes
Sleep apnea syndrome is strongly associated to type 2 diabet, partly and this is partly due to obesity. Treatment of sleep apnea may improve hypertension, cardiovascular risk and in some studies diabetes status.
- Trial name
- DIASOM (NCT01935765)
- Testing
- Polysomnography, Evaluation of the autonomous nervous system, Clinical examination of the sleep
- Where
- France
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Painful Diabetic Neuropathy, Diabetic Neuropathy, Painful
Extension of Phase 3 Gene Therapy for Painful Diabetic Neuropathy
The purpose of this study is to explore the overall safety profile and durability of efficacy of Engensis (VM202) in painful diabetic peripheral neuropathy.
- Trial name
- NCT04055090
- Testing
- Long-Term Follow-Up of Patients who Received Engensis (VM202)
- Where
- 14 sites in United States
- Volunteers
- 101 people
- Sponsor
- Helixmith Co., Ltd.
Peripheral Neuropathy
Safety and Efficacy of Mecobalamin Injection in Peripheral Neuropathies Patients (Study JGAZSY091109)
This is an open-label, randomized, multi-center clinical trial to evaluate the safety and efficacy in peripheral neuropathies patients treated with Mecobalamin Injection
- Trial name
- NCT01192113
- Testing
- Mecobalamin IV Injection, Mecobalamin IM injection, Mecobalamin IV or IM injection
- Where
- 24 sites in China
- Volunteers
- 1,072 people
- Sponsor
- Eisai Co., Ltd.
Skin Lesion, Traumatic Ulcer
Clinical Investigation EUCLIDES-01 for the Calculation of the Area of Skin Lesions
The aim of this clinical investigation is to collect skin lesion area data for the comparison of the agreement among the results obtained between the following three wound area measurement methods: Ruler using the Kundin method…
- Conditions
- Skin Lesion, Traumatic Ulcer, Hematoma, Pressure Ulcer
- Trial name
- NCT05729334
- Testing
- Clinicgram Euclides
- Where
- Spain
- Volunteers
- 65 people
- Sponsor
- Skilled Skin S.L.
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