Clinical trials: Neuroscience
Healthy Young Adults
Investigating the Inverted-U Relationship Between Cognitive Performance and Plasma Epinephrine
Abstract Although acute resistance exercise has been suggested to enhance inhibitory control, a critical component of executive function, the mechanism by which acute exercise influences inhibitory control is unclear and there…
- Trial name
- NCT05407259
- Testing
- Resistance exercise
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Aging, Cognitive Ability, General
Lifestyle Enriching Activities for Research in Neuroscience Intervention Trial: LEARNit Study
The purpose of this study is to examine the effects of modifiable lifestyle factors including exercise and healthy living on brain health. The investigators will compare 2 types of interventions, moderate aerobic walking vs.
- Trial name
- NCT02726906
- Testing
- Moderate-aerobic walking, Positron Emission Tomography (PET) scan, Healthy living education
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Stroke
Exercise and Genotype in Sub-acute Stroke
This study will investigate the impact of cardiovascular exercise on brain plasticity among patients in sub-acute stages after stroke, and whether genotype modulates the response to this intervention.
- Trial name
- NCT05076747
- Testing
- Cardiovascular training, Standard Therapy
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- McGill University
Adults, Female
Pain Science Education for Labour and Postpartum Pain
This Delphi study aims to establish expert consensus on the role, content, and delivery of pain science education (PSE) for labour and postpartum pain management.
- Conditions
- Adults, Female, Labour Pain, Postpartum Pain
- Trial name
- PNE-DELPHI (NCT07096661)
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bournemouth University
Neuroscience, Neuromodulation
Study of the Dynamics of Verbal and Non-verbal Interaction in Healthy Subjects, Through the Recording of Body Movements and Non-invasive Neurophysiological Techniques
Based on study literature, the investigators can say that our study aims to give an explanation not only from a behavioral point of view but also with respect to what are the neuronal mechanisms underlying our ability to perceive…
- Trial name
- OMNIBUS2023 (NCT06251479)
- Testing
- behavioral 1, behavioral 2, neuromodulation 1
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Chronic Pain, Educational Problems
Pain Neuroscience Education in Students
This study was designed to evaluate the effect of a 70-minute Pain neuroscience education (PNE) session on physiotherapy students' knowledge of pain and their beliefs and attitudes about the treatment of patients with chronic…
- Trial name
- NCT04007679
- Testing
- Pain neuroscience education
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Major Depressive Disorder
Glutamatergic Adaptation to Stress as a Mechanism for Anhedonia and Treatment Response With Ketamine
The main purpose of this study is to investigate the effects of ketamine on decision-making and emotion processing in a sample of individuals diagnosed with Major Depressive Disorder (MDD).
- Trial name
- NCT05327699
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Emory University
Neuroscience
Study Evaluating Absorption, Distribution, Metabolism and Excretion (ADME) of Single Dose [14C] AZD2423 in Volunteers
Phase I study to evaluate the excretion of radioactivity, the metabolic profile, pharmacokinetics, safety and tolerability following a single oral administration of [14C]AZD2423 in healthy male volunteers aged 50 to 65 years…
- Trial name
- ADME (NCT01223014)
- Testing
- AZD2423
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy
Pain Neuroscience Education in Old Adults.
The primary objectives of this study are to: Evaluate the ability of the older adults to understand the biological processes underneath a pain experience.
- Trial name
- NCT03523949
- Testing
- PNE
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Barcelona
Parkinson's Disease, Epilepsy
Cohorts and Collections: Clinical and Genetic Study of Parkinson's Disease and Epilepsies
The DNA and Cell Bank of Instituts Federatifs de Recherche (IFR) of Neurosciences has been running for the last 15 years at the Institut National de la Santé Et de la Recherche Médicale (INSERM) Unit 679 (former unit 289).
- Trial name
- NCT00142363
- Where
- 15 sites in France
- Volunteers
- 1,700 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Surveys and Questionnaires, Child
Development and Clinimetric Properties of the Dutch Pediatric Neurophysiology of Pain Questionnaire in Healthy Children
The scientific objective of this research implies developing and examining the clinimetric properties of the Dutch Pediatric Neurophysiology of Pain Questionnaire (PedNPQ) in healthy children.
- Conditions
- Surveys and Questionnaires, Child, Pain, Knowledge
- Trial name
- NCT03162835
- Testing
- Pain Neuroscience Education
- Where
- Belgium
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Vision Disorders
Bridging Animal and Human Models of Exercise-induced Visual Rehabilitation
This study will determine whether blood biomarker changes predict sight-saving benefits of exercise.
- Trial name
- NCT02911805
- Testing
- Aerobic exercise, Balance exercise
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Aging, Sleep Disorder
The Effects of Exercise on Sleep and Brain Health
Brain health and cognitive functioning can be affected by aging. Exercise is a potentially effective method for promoting "successful brain aging" by improving cardiovascular fitness, brain function and possibly sleep quality.
- Trial name
- NCT04210882
- Testing
- Moderate-Intensity Exercise
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Schizophrenia, Autism Spectrum Disorder
A Computational Neuroscience Perspective on the Shared Social Cognitive Deficits of Autism and Schizophrenia
This retrospective cohort study will examine shared neural mechanisms of social cognitive deficits in adults with autism spectrum disorder and adults with schizophrenia using existing clinical, behavioral, and neuroimaging data…
- Trial name
- NCT07618767
- Where
- Taiwan
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Alcohol Drinking, Control
Neuroscience-Informed Treatment Development for Adolescent Alcohol Use
This study will examine the effect of N-Acetylcysteine (NAC), an over-the-counter antioxidant supplement, on brains of youth (ages 15-19) using magnetic resonance imaging (MRI).
- Trial name
- NCT03238300
- Testing
- N-Acetylcysteine
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Episodic Memory, Healthy
Causal Role of Brain Networks in Episodic Memory
The goal of this study is to understand the basic brain mechanisms supporting episodic memory in healthy young adults. Transcranial magnetic stimulation will be used to influence brain activity in regions thought to be important…
- Trial name
- NCT05374551
- Testing
- Transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Boston College
Musculoskeletal Pain
Effects of Pain Neuroscience Education on Pain Attitudes and Beliefs in Physiotherapy Assistant Students
The goal of this educational trial is to learn whether Pain Neuroscience Education (PNE) improves pain-related attitudes and beliefs in physiotherapy assistant (PTA) students in Turkey compared to traditional pain education.
- Trial name
- NCT07005778
- Testing
- Traditional pain education, PNE-based education
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Neurological Disorder
Preventing Chronic Depression and PTSD in Stroke Patients Admitted to the Neuroscience Intensive Care Unit (NICU) and Their Family Caregivers
The current study has the following objectives: 1. To determine additional stroke patient (SP) and stroke caregiver (SC) factors including their perceptions of the stroke experience, hospitalization, and how they cope with its…
- Trial name
- NCT02797509
- Testing
- Psychosocial Skills-Based Intervention
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Archery, Physiotherapy and Rehabilitation
The Effect of Neuroscience-Based Exercise Training on Shooting Performance and Neuromuscular Performance in Archers
Archery is a sport that demands sport-specific motor performance, emphasizing fine motor control, postural stability, balance, and concentration skills.
- Conditions
- Archery, Physiotherapy and Rehabilitation, Muscle Activity, Visual Rehabilitation
- Trial name
- NCT07051577
- Testing
- Exercise Group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Istinye University
Pain, Educational Problems
The Effects of Pain Neuroscience Education in a Spanish-Speaking Population
Pain Neuroscience Education (PNE) has been shown to be effective to alter beliefs and decrease pain among individuals with musculoskeletal pain. Additionally, PNE has been shown to alter beliefs among middle school children.
- Trial name
- NCT03785353
- Testing
- PNE lecture
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Shenandoah University