Clinical trials: Neurosciences, open to volunteers
Fibromyalgia
Effects and Mechanisms of Pain Neuroscience Education in Patients With Fibromyalgia
This randomized controlled trials study aims, first, to determine the effectiveness of a nurse-led PNE program designed by a multidisciplinary team, compared with an active control group on pain intensity, fibromyalgia (FM)…
- Trial name
- NCT06097091
- Testing
- Self-management education, pain neuroscience education
- Where
- Taiwan
- Volunteers
- 98 people
- Sponsor
- Taipei Medical University
Diabetic Adhesive Capsulitis, Frozen Shoulder
Pain Neuroscience Education and Graded Motor Imagery Combined With Conventional Physiotherapy on Diabetic Adhesive Capsulitis
The purpose of this study is to determine the effects of Pain Neuroscience Education (PNE) and Graded Motor Imagery (GMI) combined with conventional physiotherapy on pain, kinesiophobia, central sensitization, functional…
- Conditions
- Diabetic Adhesive Capsulitis, Frozen Shoulder, Type II Diabetes Mellitus
- Trial name
- NCT07763366
- Testing
- Pain Neuroscience Education (PNE), Graded Motor Imagery (GMI), Conventional Physiotherapy
- Where
- 2 sites in Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Motoric Cognitive Risk Syndrome, Cognitive-Motor Interaction
Laser-Based Map Tests in Motoric Cognitive Risk Syndrome
This study aims to evaluate the validity and reliability of neuroscience-based visual laser feedback map tests in individuals with Motoric Cognitive Risk Syndrome (MCRS).
- Conditions
- Motoric Cognitive Risk Syndrome, Cognitive-Motor Interaction, Sensorimotor Performance
- Trial name
- NCT07572942
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Balikesir University
Carpal Tunnel Syndrome
Effectiveness of Desensitisation and Pain Neuroscience Education in Patients With Carpal Tunnel Syndrome With Nosiplastic Pain
The aim of our study was to determine the effectiveness of desensitisation and pain neuroscience education in a group of patients with mixed phenotype pain (neuropathic and nosiplastic).
- Trial name
- NCT06635213
- Testing
- Desensitisation, Pain neuroscience education
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kutahya Health Sciences University
Archery, Physiotherapy and Rehabilitation
The Effect of Neuroscience-Based Exercise Training on Shooting Performance and Neuromuscular Performance in Archers
Archery is a sport that demands sport-specific motor performance, emphasizing fine motor control, postural stability, balance, and concentration skills.
- Conditions
- Archery, Physiotherapy and Rehabilitation, Muscle Activity, Visual Rehabilitation
- Trial name
- NCT07051577
- Testing
- Exercise Group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Istinye University
Low Back Pain
Neuroscience Education and Spinal Manipulation on Health Locus of Control in Low Back Pain
The purpose of this study is to evaluate the effects of combining Pain Neuroscience Education (PNE) with spinal manipulation for individuals suffering from chronic low back pain.
- Trial name
- LHC-LBP (NCT07639216)
- Testing
- Pain Neuroscience Education (PNE), Spinal Manipulation (SM)
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- Centro Universitário Augusto Motta
Fibromyalgia (FM), Chronic Low Back Pain (CLBP)
Pain Neuroscience Education for Chronic Pain
Chronic pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, with a high prevalence in Spain (25.9%) and an average duration of 6.83 years, highlighting its significant health…
- Conditions
- Fibromyalgia (FM), Chronic Low Back Pain (CLBP), Chronic Pain
- Trial name
- PNE (NCT07693998)
- Testing
- Therapeutic Exercise and Education in Pain Neuroscience
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- University of Valencia
Non Specific Low Back Pain
Effects of Pain Neuroscience Education on Pain, Kinesiophobia in Patients With Non Specific Low Back Pain
Chronic non-specific low back pain (NSLBP) is a highly prevalent musculoskeletal condition and a leading cause of disability worldwide.
- Trial name
- NCT07460011
- Testing
- Core stabilization exercises, Pain neuroscience education + core stabilization
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Benzodiazepine Adverse Reaction, Depression, Anxiety
Benzodiazepine Impact on Cognitive Function: fNIRs and PET/MRI Study
This study explores the impact of long-term benzodiazepine (BZDs) use on cognitive function and associated neuroimaging markers.
- Conditions
- Benzodiazepine Adverse Reaction, Depression, Anxiety, Benzodiazepine Dependence
- Trial name
- NCT06250842
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Dalian Medical University
Social Dynamics
Brain-to-brain Synchrony in Ss With Different Levels of Social Interaction
Brain-to-brain synchrony will be measured between pairs of subjects with different levels of similarity of DNA and social interactions
- Trial name
- NCT06673589
- Testing
- Transcendental Meditation
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maharishi International University
Chemotherapy-Related Cognitive Impairment, Chemotherapeutic Toxicity
Investigating Cognitive Impairment in Young Patients With Cancer Prospectively
The MyBrain study investigates the brain function of children, adolescents and young adults during and after chemo treatment for cancer.
- Conditions
- Chemotherapy-Related Cognitive Impairment, Chemotherapeutic Toxicity, Chemo-brain, Cancer
- Trial name
- MyBrain (NCT05840575)
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Promoting Active Inference of Healthy Older Adults With Language Activity
A Language-Based Training Intervention to Enhance Cognitive Health in Community-Dwelling Older Adults
Taiwan is fast approaching a super-aged society, making it urgent to bolster cognitive health in otherwise healthy older adults.
- Trial name
- NCT07132281
- Testing
- Language activities active inference, Language activities passive, Board Games
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Osteoarthritis, Knee
Effects of Including a Chronic Pain Neuroscience Education Program for Individuals With Knee OA
Research participants diagnosed with knee osteoarthritis will be randomized through a draw using sealed opaque envelopes indicating two groups: 1. therapeutic exercises, 2.
- Trial name
- NCT06187038
- Testing
- Therapeutic exercises, Therapeutic exercises + pain neuroscience education program
- Where
- Brazil
- Volunteers
- 92 people
- Sponsor
- University of Nove de Julho
Pain, Normal Physiology
Neural and Psychological Mechanisms of Pain Perception
Background: Painful stimuli cause changes in a network of brain regions called the "Pain Matrix." But most of these regions respond to many other stimuli, not just pain.
- Conditions
- Pain, Normal Physiology, Healthy Volunteers
- Trial name
- NCT02446262
- Testing
- Instructions, Attention, Thermal Pain
- Where
- United States
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Depression Mild, Depression
fMRI Neurofeedback With Matter Neuroscience App
Study will utilize an app, Matter Neuroscience, designed to help users with depression understand positive emotions and the neurotransmitters that create them.
- Conditions
- Depression Mild, Depression, Depression Moderate
- Trial name
- NCT06735885
- Testing
- Matter Neuroscience App, Stock Photos, No Home Training
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Stanford University
Healthy Aging, Healthy
The Effect of Different Focus of Attention Instructions on Resistance Training and Its Transfer to Gait Parameters in Older Adults
The goal of this clinical trial is to investigate the effects of strength training with different focus of attention strategies on plantar flexor force and how this affects gait in apparently healthy older adults.
- Trial name
- NCT06538766
- Testing
- Strength training with an internal focus of attention, Strength training with a proprioceptive external focus of attention, Strength training with a visual external focus of attention
- Where
- Portugal
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Chronic Pain
Pain Neuroscience Education and Memory
Brief Summary: The goal of this observational study (case series) is to determine whether Pain Neuroscience Education (PNE) can influence memory function and sensory awareness in adults (18 years and older) experiencing chronic…
- Trial name
- PNE (NCT07252596)
- Testing
- Pain Neuroscience Education (PNE)
- Volunteers
- 50 people
- Sponsor
- Evidence In Motion
Adults, Female
Pain Science Education for Labour and Postpartum Pain
This Delphi study aims to establish expert consensus on the role, content, and delivery of pain science education (PSE) for labour and postpartum pain management.
- Conditions
- Adults, Female, Labour Pain, Postpartum Pain
- Trial name
- PNE-DELPHI (NCT07096661)
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bournemouth University
Fibromyalgia
Pain Neuroscience Education, Conditioned Pain Modulation and Emotional Processes in Fibromyalgia
Chronic pain represents a significant public health concern worldwide and is a primary reason why patients seek specialized medical care.
- Trial name
- NEUROPAINFIB (NCT07055971)
- Testing
- Experimental: Pain Neuoescience Education Group, Active Comparator: Biomedical Education Group
- Where
- Spain
- Volunteers
- 46 people
- Sponsor
- Universidad de Granada
Low Back Pain, Recurrent
Effectiveness of a Pain Neuroscience Education Programme on Physical Activity in Patients With Chronic Low Back Pain
Proposing ways to effectively counter chronic low back pain through non-drug intervention is a major public health issue due to the prevalence and health costs of this condition.
- Trial name
- END-LC (NCT05840302)
- Testing
- Activity monitor, Questionnaire
- Where
- France
- Volunteers
- 82 people
- Sponsor
- University Hospital, Montpellier