Clinical trials: Neurotypical
Neurotypical, Cognitively Normal
Brain Vascular and Neural Function Linked to Balance Across the Adult Lifespan
This is a single-arm, two-visit, non-randomized, cross sectional study identified as an intervention due to the use of a single bout of aerobic exercise to assess cerebrovascular function under the NIH rules.
- Trial name
- NCT06127667
- Testing
- aerobic exercise
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Autism Spectrum Disorders
A Comparative Study of Driving Performance Among Adolescents With Autism Spectrum Disorder and Neurotypical Adolescents
The primary objective of this study is to compare the number of driving errors made by novice adolescents (0-5 hours of driving instruction) with ASD to those made by neurotypical adolescents during a standardized driving…
- Trial name
- Perf-TSA (NCT07630298)
- Testing
- Assessment of executive functions and attention, Evaluation on a driving simulator, Evaluation on-road
- Where
- France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Hopital La Musse
Autism, Autism Spectrum Disorder
Static Balance in Children With Autism vs. Neurotypical Peers
The Virtual Reality Rehabilitation System (VRRS) is an innovative and sophisticated technology, aimed to generate immersive and interactive settings intended for therapeutic and evaluative objectives.
- Trial name
- NCT06152510
- Testing
- Virtual Reality Rehabilitation System
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Internet Addiction
The Effect of the Mobile EEG-Neurofeedback in Healthy Child and Adolescent
The objective of this study was to ascertain the therapeutic impact of mobile neurofeedback (MNF) in neurotypical children when compared to sham MNF.
- Trial name
- NCT06388655
- Testing
- mobile neurofeedback
- Where
- South Korea
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Daegu Catholic University Medical Center
Autism Spectrum Disorder (ASD), Neurotypical
Course of Face-to-face Interactions in Adults With Autism
This research explores how adults with autism make eye contact during formal and informal interactions; to what extent the nature of a conversation influences how eye contact is made in terms of length, frequency and overall…
- Trial name
- NCT06925308
- Testing
- Conversation
- Where
- Netherlands
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Persisting Primitive Reflexes
Preschool Children Motor Development
The preschool age period is crucial for motor and cognitive development, which retention primary reflexes can negatively influence.
- Trial name
- NCT06071000
- Testing
- Neuro-developmental stimulation (Neuro-vývojová stimulace).
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Healthy Volunteer
NEURO-IS: Neurophysiology of Inner Speech Across Neurotypical Participants.
The purpose of this study is to investigate the brain activity associated with two common inner experiences: visual mental imagery (mentally seeing objects or actions) and inner speech (experiencing language without speaking out…
- Trial name
- NEURO-IS (NCT07885020)
- Testing
- Inner Experience Induction Tasks and hdEEG
- Where
- Belgium
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Liege
ADHD, Healthy
Effects of EEG- Microstate Neurofeedback on Attention and Impulsivity in Adult Attention-deficit/Hyperactivity Disorder (ADHD) and Neurotypical Controls
EEG neurofeedback (NFB) may represent a new therapeutic opportunity for ADHD, a neuropsychiatric disorder characterized by attentional deficits and high impulsivity.
- Trial name
- ADHDmicroNFB (NCT05582928)
- Testing
- Neurofeedback
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nader Perroud
Juvenile Neuronal Ceroid Lipofuscinosis, Smith-Lemli-Opitz Syndrome
Functional Near-Infrared Spectroscopy (fNIRS) Combined With Diffuse Correlation Spectroscopy (DCS) in Neurocognitive Disease as Compared to Healthy Neurotypical Controls
Background: Neurocognitive disorders affect how the brain uses oxygen. They may affect mental development in children. These disorders can be studied with imaging scans that use radiation; however, these methods are not ideal for…
- Conditions
- Juvenile Neuronal Ceroid Lipofuscinosis, Smith-Lemli-Opitz Syndrome, Creatine Transporter Deficiency, Niemann-Pick Disease Type C1
- Trial name
- NCT05642221
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Dental Phobia, Dental Anxiety
The Impact of Medical Play in the Dental Clinic Setting on the Cooperation of Neurotypical Patients
The purpose of this pilot study is to investigate the efficacy of medical play in the dental setting to improve the behaviors and cooperation of neurotypical patients during dental visits.
- Conditions
- Dental Phobia, Dental Anxiety, Oral Aversion
- Trial name
- NCT05571423
- Testing
- Medical Play, Routine Play
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Stroke, Cerebellum
Imaging Speech in Neurotypical Adults and Individuals With Cerebellar Stroke
The goal of this research study is to learn how the brain areas that plan and control movement interact with the areas responsible for hearing and perceiving speech in healthy adults and people who have had cerebellar strokes.
- Trial name
- NCT06458153
- Testing
- Neural responses to speech functional localizer, Neural responses to silent articulation, Neural responses to self vs. externally generated speech
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Autism Spectrum Disorder (ASD), Neurotypical
Autistic Eye Contact?
This research explored both breadth and depth of the experiences with eye contact in adults with and without ASD. A hermeneutic phenomenological multicenter design was used in which 15 adults with ASD and 15 adults without ASD…
- Trial name
- NCT06921876
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Neurotypical Adults
Targeting Personalized Brain States Reflecting Strong and Weak Corticospinal Tract Output in Real-time
Transcranial magnetic stimulation (TMS) interventions could feasibly strengthen residual corticospinal tract (CST) connections and enhance recovery of paretic hand function after stroke.
- Trial name
- NCT06365086
- Testing
- Personalized brain state-dependent single-pulse TMS
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Force Measurement, Children
Lower Extremity Dynamometry Assessment in Neurotypical Children
The purpose of this study is to assess the reliability (intra-rater and inter-rater) and criterion validity (using a Cybex isokinetic dynamometer as the reference) of the K-Pull (traction) dynamometer for evaluating lower limb…
- Conditions
- Force Measurement, Children, Lower Limb, Assessment Tool
- Trial name
- NCT06667492
- Testing
- Traction Dynamometry
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Attention Deficit Hyperactivity Disorder, Psychiatric Diagnosis
Neurophysiological Marker of ADHD in Children
This study investigated quantitative electroencephalography (QEEG) subtypes as auxiliary tools to assess Attention Deficit Hyperactivity Disorder (ADHD).
- Conditions
- Attention Deficit Hyperactivity Disorder, Psychiatric Diagnosis, Diagnosis, Psychiatric
- Trial name
- NCT04467658
- Testing
- electroencephalography absolute delta power, electroencephalography relative delta power, electroencephalography absolute theta power
- Where
- South Korea
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Daegu Catholic University Medical Center
Autism Spectrum Disorder, Autism
Faecal Microbiota Analysis in Neurotypical and Autism Syndrome Disorder Siblings
This study aims to accurately characterise the gut microbiota composition of faeces of children with ASD and compare it with the gut microbiota composition of their neurotypical siblings.
- Trial name
- FAMILY (NCT05794620)
- Testing
- Stool sample
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- East Suffolk and North Essex NHS Foundation Trust
ASD
A Sensory-Profile Framework for Differentiated Swim Instruction in Autistic Children
Autistic children drown at one-hundred sixty times the rate of their neurotypical peers: a public health crisis that the adapted learning field has only addressed by demonstrating that standard swimming instruction sometimes…
- Trial name
- NCT07699692
- Testing
- sensory-based instruction, standard instruction
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Genesis Indep Research
Fragile X Syndrome (FXS), Neurotypical Adults
Neural Biomarkers in Fragile X Syndrome
The purpose of this non-interventional test /re-test study is to assess neural biomarkers in adult subjects with Fragile X syndrome compared to those measured in a population of typically developing adults
- Trial name
- EXP-CTH120 (NCT06957054)
- Testing
- Any
- Where
- 2 sites in Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Connecta Therapeutics, S.L.
Stuttering, Developmental, Aphasia, Primary Progressive
Investigating Speech Sequencing in Neurotypical Speakers and Persons With Disordered Speech
Persistent developmental stuttering affects more than three million people in the United States, and it can have profound adverse effects on quality of life.
- Trial name
- NCT05437159
- Testing
- Learning of non-native phoneme combinations: 6 training sessions, Learning of non-native phoneme combinations: 1 training session, Learning of novel multisyllabic nonwords
- Where
- 3 sites in United States
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Stuttering, Developmental, Dyslexia
Investigating Individual Differences in Speech Motor Skills in Neurotypical Speakers and Persons With Disordered Speech
This study aims to understand how people use different types of feedback to control their speech. When an individual speaks, the brain relies on several systems at the same time, such as sensory systems that monitor an…
- Conditions
- Stuttering, Developmental, Dyslexia, Healthy Participants
- Trial name
- NCT07459803
- Testing
- Unpredictable auditory feedback perturbation: 2 behavioral sessions, Unpredictable auditory feedback perturbation during tCS: 3 behavioral sessions, Sustained F1 auditory feedback perturbation
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus