Clinical trials: Nodular Goiter
Pleuropulmonary Blastoma, Sertoli-Leydig Cell Tumor
International PPB/DICER1 Registry
PPB has strong genetic implications, with a unique set of conditions in an individual or their family, occurring mostly in childhood and adolescence.
- Conditions
- Pleuropulmonary Blastoma, Sertoli-Leydig Cell Tumor, DICER1 Syndrome, Cystic Nephroma
- Trial name
- NCT03382158
- Where
- United States
- Volunteers
- 3,400 people, healthy volunteers welcome
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Hypocalcemia, Hypoparathyroidism
NIRAF-Guided Parathyroid Identification During Thyroidectomy
This is a single-site, two-component prospective study evaluating whether near-infrared autofluorescence (NIRAF) imaging can improve intraoperative identification of parathyroid glands during thyroidectomy and reduce…
- Conditions
- Hypocalcemia, Hypoparathyroidism, Thyroid Diseases, Goiter, Nodular
- Trial name
- NCT07617584
- Testing
- Wearable Near-Infrared Autofluorescence Imaging System
- Where
- North Macedonia
- Volunteers
- 280 people
- Sponsor
- Ss. Cyril and Methodius University of Skopje
Goiter, Thyroid Disease
Dysphagia After Thyroidectomy
The goal of this observational study is to develop a questionnaire for measuring swallowing and throat discomfort symptoms in patients with goiter or thyroidectomy, which complies with the model of Rasch and which satisfies the…
- Trial name
- DYSPHATHYR (NCT06296420)
- Where
- Italy
- Volunteers
- 420 people
- Sponsor
- Istituto Auxologico Italiano
Nodular Goiter
TACE Treats Nodular Goiter
transarterial bleomycin chemoembolization represents a novel minimally invasive therapeutic approach for the management of giant nodular goiter.
- Trial name
- NCT07258199
- Testing
- TACE
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking Union Medical College Hospital
Goiter, Nodular, Total Thyroidectomy
Thyroid Cancer in Surgical Treated Multinodular Goiter
This study aims to investigate, based on existing knowledge, the incidence of occult thyroid carcinoma in a cohort of patients with MNG, providing new insights into the prevalence and characteristics of thyroid malignancies in…
- Conditions
- Goiter, Nodular, Total Thyroidectomy, Thyroid Cancer
- Trial name
- NCT06924242
- Testing
- total or partial thyroidectomy
- Where
- Italy
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- University of Foggia
Graves Disease, Goiter, Nodular
Role of Embolization of Thyroid Arteries as a Treatment for Different Thyroid Disorders
To investigate the safety and efficacy of selective embolization of thyroid arteries (SETA) as adjunctive or definitive treatment in different thyroid disorders
- Conditions
- Graves Disease, Goiter, Nodular, Goiter Malignant, Goiter Diffuse
- Trial name
- NCT06537141
- Testing
- selective embolization of thyroid arteries (SETA)
- Volunteers
- 20 people
- Sponsor
- Assiut University
Medullary Thyroid Carcinoma, Nodular Goiter
Calcitonin in Needle Wash Using Electrochemiluminescence Method For Diagnosis Of Medullary Thyroid Carcinoma.
Medullary thyroid carcinoma (MTC) is a tumor originating from parafollicular C cells of the thyroid. (1) Representing 1 to 7% of all thyroid carcinoma cases (2, 3, 4).
- Trial name
- NCT06067594
- Testing
- Fine Needle Aspiration Cytology (FNAC) procedure+calcitonin measurement
- Where
- Argentina
- Volunteers
- 155 people
- Sponsor
- Austral University, Argentina
Thyroid Nodule
Effect of Dill in Thyroiditis and Nodular Goiter Patients
The aim of the study was to investigate the functional and morphological effects of Anethum graveolens L. in patients with thyroiditis and nodular goiter by evaluating hormone levels, anti-Inflammatory markers and comparing…
- Trial name
- Dill (NCT04482907)
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Bezmialem Vakif University
Thyroid Neoplasms, Goiter, Nodular
Study of the Efficacy of Local Analgesia as an Adjunct to General Anesthesia in Thyroidectomy and Parathyroidectomy
We aim to study the effect of local anesthetic when used in conjunction with general anesthesia during thyroidectomy or parathyroidectomy.
- Conditions
- Thyroid Neoplasms, Goiter, Nodular, Thyroid Nodule, Graves' Disease
- Trial name
- NCT02205801
- Testing
- Superficial Cervical Plexus Block, Local Wound Infiltration, 0.9% saline
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Chicago
Goiter, Nodular
Tracheal Anatomy After Thyroidectomy
The investigators aimed at investigating the effects of thyroidectomy on tracheal anatomy and airflow in patients with benign nodular goiter, employing a prospective observational study.
- Trial name
- NCT03072654
- Testing
- Thyroidectomy
- Volunteers
- 72 people
- Sponsor
- University of Southern Denmark
Goiter, Nodular
Galectin 3 Dosage in Diagnosis of Nodular and Multinodular Goiter
The investigators will dose galectin 3 in plasma and water rinse of the needle aspiration biopsy in patients with thyroid nodules.
- Trial name
- Galectins (NCT01588288)
- Testing
- Galectin 3 dosage
- Where
- 2 sites in France
- Volunteers
- 193 people
- Sponsor
- University Hospital, Rouen
Nodular Goiter
rhTSH, Radioiodine Uptake and Goiter Reduction Following 131I Therapy in Patients With Benign Nontoxic Nodular Goiter
The study aims at clarifying (in a randomized, double-blinded design): 1. Whether stimulation with 0.1 mg rhTSH 24, 48 or 72 hours before induction of a 131I-tracer dosis increases the 131I uptake in patients with atoxic…
- Trial name
- NCT00275171
- Testing
- Recombinant human thyrotropin (Thyrogen), recombinant human TSH
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Steen Bonnema
Nodular Goiter
Effect of Higher Doses of Remifentanil on Postoperative Pain in Patients Undergoing Thyroidectomy
Extensive clinical studies have shown that intraoperative infusion high dose of remifentanil (0.2ug/kg/min) induced postoperative hyperalgesia.
- Trial name
- NCT01761149
- Testing
- Remifentanil
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Central South University
Nodular Goiter, Thyroid Cancer
Elastography in Thyroid Nodules
Nodular goiter is a highly prevalent disease in iodine-deficient areas. Usually nodule assessment includes ultrasonography (US) and fine-needle aspiration (FNA), but some benign nodules can hardly be distinguished from…
- Trial name
- NCT01102127
- Testing
- Elastography
- Where
- Spain
- Volunteers
- 128 people
- Sponsor
- Castilla-León Health Service
Thyroid Nodule, Thyroid Cancer
Pilot Study on Laser Ablation of Symptomatic Benign Thyroid Masses
This proposal is designed as a pilot study for the use of laser ablation for local control of symptomatic (e.g compressive) benign thyroid masses in 20 patients.
- Conditions
- Thyroid Nodule, Thyroid Cancer, Thyroid Neoplasms, Nodular Goiter
- Trial name
- NCT00615537
- Testing
- Laser Ablation of Thyroid Nodule
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- BioTex, Inc.
Goiter, Nodular
LISA-study : Levothyroxin in Nodular Goiter
Primary objective: To evaluate change in total volume of all nodules. Secondary objectives: To evaluate change in goiter volume after a 12-months treatment, number of nodules and echogenicity of nodules.
- Trial name
- NCT00277589
- Testing
- Levothyroxin-Na, Levothyroxine-Na + iodide, Iodide
- Where
- Germany
- Volunteers
- 1,024 people
- Sponsor
- Sanofi
Goiter
Outcomes of Different Thyroid Resections for Multinodular Non-toxic Goiter
The aim of this three-arm randomized study was to evaluate results of different thyroid resection modes among patients with bilateral multinodular non-toxic goiter, with special emphasis put on recurrence rate and morbidity rate…
- Trial name
- NCT00946894
- Testing
- Total thyroidectomy, Dunhill operation, Bilateral subtotal thyroidectomy
- Where
- Poland
- Volunteers
- 600 people
- Sponsor
- Jagiellonian University
Recurrent Goiter
Thyroid Lobectomy With or Without Levothyroxine Treatment Postoperatively
The aim of this study was to compare the prevalence of recurrent nodular goiter in the contralateral thyroid lobe among patients after unilateral thyroid lobectomy for unilateral multinodular goiter receiving versus not receiving…
- Trial name
- NCT00941551
- Testing
- levothyroxine, no levothyroxine
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Jagiellonian University