Clinical trials: Non-pharmacological Intervention
Depression, Generalized Anxiety
The Mental Health Status of the General Population During the COVID-19 Pandemic and Its Association With Adherence to Government-initiated Non-pharmacological Epidemiological Interventions (NPI's)
This study seeks to investigate the levels of common psychopathology symptoms (i.e., depression and generalized anxiety) in a general population during the strict social distancing government-initiated non-pharmacological…
- Conditions
- Depression, Generalized Anxiety, Adherence to Non-pharmacological Epidemiological Interventions (NPIs)
- Trial name
- NCT04356365
- Testing
- Cross-sectional study investigating the association of NPIs with mental health
- Where
- Norway
- Volunteers
- 10,084 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Cardiovascular Disease
Effectiveness of Non-pharmacological Interventions in Patients With Cardiovascular Risk Factors in Primary Care
The principal objective is analyzed whether a selective intervention no pharmacological (use of ABPM +/- prescription of physical exercise) for cardiovascular risk factors in patients with high cardiovascular risk in primary…
- Trial name
- NCT03452709
- Testing
- therapeutic exercise, ABPM ambulatory blood pressure monitoring
- Where
- Spain
- Volunteers
- 3,656 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
Myasthenia Gravis
Integrating Art Therapy and Adapted Physical Activity: Toward Improved Quality of Life in Patients With Myasthenia Gravis
Myasthenia Gravis (MG) is a rare neuromuscular disease characterized by fluctuating muscle weakness and excessive fatigability. Although medical treatments have improved, MG continues to significantly impact patients' physical…
- Trial name
- APART-MG (NCT07125105)
- Testing
- Adapted Physical Activity Only, Adapted Physical Activity + Art Therapy
- Where
- France
- Volunteers
- 102 people
- Sponsor
- Universite du Littoral Cote d'Opale
Subjective Cognitive Decline (SCD), Mild Cognitive Impairment (MCI)
Positive Psychology for Early Cognitive Decline: Effects on Cognitive and Brain Function
This randomized study tests whether a new multicomponent Positive Psychology program can improve cognition and wellbeing in older adults at the earliest stages of dementia-related decline.
- Conditions
- Subjective Cognitive Decline (SCD), Mild Cognitive Impairment (MCI), Alzheimer Dementia (AD)
- Trial name
- NCT07289061
- Testing
- Positive Psychology Intervention, Treatment as usual (TAU)
- Where
- Greece
- Volunteers
- 128 people
- Sponsor
- Aristotle University Of Thessaloniki
Tinnitus
FR-taVNS Tinnitus Tria
Tinnitus is a common neurosensory symptom affecting 12-30% of adults and is closely associated with anxiety, sleep disturbance, and autonomic dysregulation.
- Trial name
- NCT07711639
- Testing
- True Foot Reflexology, True ta-VNS, True Auricular Acupressure
- Where
- Taiwan
- Volunteers
- 180 people
- Sponsor
- Tzu Chi University
Pneumonia
Effect of Pursed-Lip Breathing on Physiological Parameters and Discharge Readiness in Children With Pneumonia
This study aims to evaluate the effects of Pursed-Lip Breathing (PLB) exercises on physiological parameters (such as respiratory rate, heart rate, and oxygen saturation) and discharge readiness in children diagnosed with…
- Trial name
- PLB-PEDPNEU (NCT07106203)
- Testing
- Pursed-Lip Breathing (PLB)
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Ataturk University
Neonatal Abstinence Syndrome
Efficacy and Outcomes of a Non-Pharmacological Intervention for Neonatal Abstinence Syndrome
The purpose of this study is to examine the efficacy of a specially-constructed crib mattress that delivers gentle vibrations (stochastic vibrotactile stimulation) as a complementary, non-pharmacological intervention for treating…
- Trial name
- NCT02801331
- Testing
- Stochastic Vibrotactile Stimulation (SVS)
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- Elisabeth B Salisbury
Pregnancy, Delivery Care
Effects of Massage and Shower on Birth Experience and Breastfeeding
Study Design This study is a quasi-experimental research designed to examine the effects of massage and warm shower-used as non-pharmacological methods during labor-on birth satisfaction, maternal comfort, and breastfeeding…
- Trial name
- NCT07151144
- Testing
- Massage, Shower
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Alzheimer Disease, Early Onset, Parkinsons Disease with Dementia
Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease
The goal of this Multicenter observational pilot study is to Compare the specifics of musical engagement (behaviors related to music in everyday life) in subjects aged over 60 with Alzheimer s disease, Parkinson s disease and…
- Conditions
- Alzheimer Disease, Early Onset, Parkinsons Disease with Dementia, Non Pharmacological Intervention
- Trial name
- MUSENGAGE (NCT06688968)
- Testing
- neuropsychologist interview, questionnaire
- Where
- 3 sites in France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Chronic Kidney Diseases, Pain, Procedural
Effect of 4-7-8 Breathing on AV Fistula Needle Pain in Dialysis Patients
For many hemodialysis patients, needle insertion into the vascular access site (fistula) is a significant source of pain and anxiety.
- Conditions
- Chronic Kidney Diseases, Pain, Procedural, Arteriovenous Fistula
- Trial name
- NCT07700680
- Testing
- Breathing technique
- Volunteers
- 80 people
- Sponsor
- Izmir Kavram Vocational School
Prevention of Procedural Pain, Reduction of Procedural Pain
Non-pharmacological Interventions for Procedural Pain in Premature Neonates
A. Specific Aims Premature infants admitted to the neonatal intensive care unit (NICU) require up to several hundred procedures during their hospitalization.
- Conditions
- Prevention of Procedural Pain, Reduction of Procedural Pain, Biochemical Effects of Oral Dextrose
- Trial name
- NCT02214589
- Testing
- Oral glucose, facilitated tucking, NNS, Oral glucose and NNS, Facilitated tucking and NNS
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Loma Linda University
Androgenetic Alopecia
Clinical Evaluation of Localized Scalp Thread Embedding for Male Androgenetic Alopecia
This clinical study aims to evaluate a breakthrough treatment for hair loss (androgenetic alopecia, AGA) using dissolvable threads placed under the scalp skin.
- Trial name
- NCT06879119
- Testing
- Localized scalp thread embedding
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Beijing University of Chinese Medicine, Shenzhen Hospital
Cancer Survivor, Fatigue
Home-Based Programs for Improving Sleep in Cancer Survivors
RATIONALE: Following a program that uses written materials and pre-recorded mp3 devices may help improve the sleep of cancer survivors.
- Conditions
- Cancer Survivor, Fatigue, Psychosocial Effects of Cancer and Its Treatment, Sleep Disorders
- Trial name
- NCT00993928
- Testing
- Home-based sleep intervention
- Where
- 193 sites in United States
- Volunteers
- 93 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Parkinson Disease
Kick Out Parkinson's Disease 2
The benefits of exercise for general health and well-being in older adults are well-established. Balance exercises such as tai chi and yoga, along with resistance training, can improve or maintain physical function in older…
- Trial name
- NCT03882879
- Testing
- Karate Classes, Pre-Intervention Study Visit, Bimonthly Online Survey
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Rush University Medical Center
Colonoscopy, Sedation
Non-pharmacological Intervention for Colonoscopy
The purpose of this study is to determine whether a non-pharmacological intervention reduces consumption of sedative drugs during colonoscopy. A reduction of sedative drugs may reduce side effects.
- Conditions
- Colonoscopy, Sedation, Hypnosis
- Trial name
- NCT00913861
- Testing
- hypnosis, standard sedation, Structured attention
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- University Hospital, Geneva
Mild Cognitive Impairment, Mild Dementia
Shanghai Non-pharmacological Intervention for Mild Cognitive Impairment and Mild Alzheimer's Disease
This study is a multicentre, randomized, double-blind, controlled trial that aims to investigate the efficacy of multi-domain life-style intervention including low inflammatory-index diet, exercise, and cognitive training in…
- Trial name
- SIM-2 (NCT05887674)
- Testing
- Diet intervention, Exercise, Cognitive training
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Ruijin Hospital
Willis-Ekbom Disease, Restless Legs Syndrome (RLS)
EXPLORATORY STUDY OF THE POTENTIAL OF THERAPEUTIC EXERCISE IN THE TREATMENT OF WILLIS-EKBOM DISEASE
The goal of this clinical trial is to learn whether a home-based therapeutic exercise program can improve symptoms of restless legs syndrome (RLS), also known as Willis-Ekbom disease, in adults with chronic RLS.
- Trial name
- NCT07810127
- Testing
- Myofascial Self-Stretching Exercise Program, Buerger-Allen Exercise Program
- Where
- Spain
- Volunteers
- 27 people
- Sponsor
- Universidad Pontificia Comillas
Diabetes Mellitus, Type 1
Effects of Low Intensity Aerobic Exercise on the Microvascular Endothelial Function of Patients With Type 1 Diabetes
Background: The aim of the present study was to evaluate the changes in the microvascular density and reactivity in patients with type 1 diabetes (T1D) resulting from low intensity chronic exercise training.
- Trial name
- NCT02441504
- Testing
- Low intensity Exercise
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Cardiologia de Laranjeiras
Primary Dysmenorrhea (PD)
Graded Motor Imagery for Primary Dysmenorrhea
The goal of this clinical trial is to learn if graded motor imagery can reduce pain sensitivity and period pain in women with primary dysmenorrhea (painful periods with no medical cause).
- Trial name
- NCT07618832
- Testing
- Graded Motor Imagery (GMI)
- Where
- Pakistan
- Volunteers
- 81 people
- Sponsor
- Dr. Mehak Naeem
Sleep Disturbance in Advanced Cancer
Sleep Well At Night
Research has shown that the incidence of sleep disturbances in people with cancer is much higher than in the general population. Sleep problems can lead to worse symptoms, quality of life, and potentially impact outcomes.
- Trial name
- SWAN (NCT07068971)
- Testing
- Online cognitive behavioural therapy for insomnia, bright light therapy, activity
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- Our Lady's Hospice and Care Services