Clinical trials: Normal Skin
Acne Vulgaris
Clinical Pharmacist Role in Adherence to Recommendations Among Isotretinoin Users
The objective of the study was to evaluate the role of clinical pharmacists in improving adherence to medication and the recommendations related to isotretinoin, awareness about proper use, dealing with the side effects, and…
- Trial name
- NCT05839223
- Testing
- Education
- Where
- Jordan
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Pharmacokinetics
The Study to Assess the Pharmacokinetics of Pimicotinib in Subjects With Mild and Moderate Hepatic Impairment Relative to Subjects With Normal Hepatic Function
This is a phase 1, open-label, parallel-group, single-center study to evaluate the pharmacokinetics and safety of a single 25 mg oral dose of pimicotinib in subjects with mild and moderate hepatic impairment and in control…
- Trial name
- NCT06562946
- Testing
- Pimicotinib
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Abbisko Therapeutics Co, Ltd
Dental Pulp Necrosis, Periapical Periodontitis
Measurement of Bite Force in Humans
This protocol is for a clinical trial to evaluate the reliability of the bite fork as a diagnostic instrument in subjects with pulpal necrosis and apical periodontitis.
- Trial name
- NCT00223327
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Diabetes Mellitus, Hypertension
Evidence-based Laboratory Test Order Sets in Primary Care
Cluster randomised controlled trial to evaluate what the effect is of evidence-based order sets aimed at five indications on the appropriateness of laboratory test ordering in primary care.
- Conditions
- Diabetes Mellitus, Hypertension, Cardiovascular Diseases, Fatigue
- Trial name
- NCT02950142
- Testing
- CPOE with order sets for lab testing, CPOE without order sets for lab testing
- Where
- Belgium
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Breast Cancer
Screening in Myocardial Perfusion Patients
To expand the understanding of the uptake and distribution of Tc-99m sestamibi in the breast in a normal female population undergoing myocardial perfusion imaging using Molecular Breast Imaging (MBI).
- Trial name
- NCT00943241
- Where
- United States
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Pain
In Vitro Studies on Pharmacological Regulation and Genetic Risk Factors of Peripheral Human Nociceptors
This protocol is for a number of in vitro studies using human surgical biopsies and evaluating the pharmacology and genetics of human nociceptors ("pain detecting") neurons
- Trial name
- NCT00223366
- Where
- United States
- Volunteers
- 2,007 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Hidradenitis Suppurativa, Scarring
Efficacy and Tolerability of a Fractional Ablative Erbium Laser for Axillary Scarring for Hidradenitis Suppurativa Patients
Single center, open-label, baseline-controlled study evaluating the use of a Sciton fractionated ablative laser in the treatment of Hidradenitis Suppurativa (HS) scarring.
- Trial name
- NCT05470322
- Testing
- Er: YAG laser
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Propionic/Methylmalonic Acidemias, Maple Syrup Urine Disease
Selective Screening of Children for Hereditary Metabolic Diseases by Tandem Mass Spectrometry in Kazakhstan
Inborn errors of metabolism (IEM) are not have specific clinical signs, they masquerade as other diseases, and are difficult to diagnose using only clinical manifestations or routine laboratory tests.
- Conditions
- Propionic/Methylmalonic Acidemias, Maple Syrup Urine Disease, Citrullinemia, Argininosuccinic Aciduria
- Trial name
- NCT05910151
- Testing
- Obtaining Dry Blood Spots From Healthy Newborns (Aged 1-7 Days), Obtaining Dry Blood Spots From Healthy Children Aged 8 Days - 7 Years, Obtaining Dry Blood Spots From Healthy Children Aged 8-18 Years
- Where
- Kazakhstan
- Volunteers
- 2,250 people, healthy volunteers welcome
- Sponsor
- West Kazakhstan Medical University
Breast Cancer
Evaluation of Mailers Promoting Mammogram Screening
In this evaluation, 3 different versions of mailers promoting annual mammograms are being sent to women on the month of their 50th and 64th birthdays.
- Trial name
- NCT04555902
- Testing
- Postcard, Small Gift, Loss Frame and Fear Appeals
- Where
- United States
- Volunteers
- 1,342 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Breast Cancer
An Impact Assessment of a Culturally Tailored Online Psychosocial Program for Chinese Immigrant Women With Breast Cancer
The purpose of the study is to evaluate the effectiveness of an online psychosocial self-help program for Chinese immigrant women with breast cancer, by comparing Chinese immigrant women who receive the online psychosocial…
- Trial name
- NCT04656353
- Testing
- Intervention Arm, Control Group
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Overweight, Obesity
Exercise Genes: Genomic Association With Exercise Reinforcement
This study tests whether different physical activity patterns are linked an individual's genes.
- Conditions
- Overweight, Obesity, Physical Activity
- Trial name
- ExGenes (NCT02416882)
- Testing
- Aerobic Exercise, Resistance Exercise, Sedentary Option
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Healthy Volunteers
Safety, Tolerability and Pharmacokinetic Study of MRG-201 in Healthy Volunteers
The primary objective of this study is to evaluate the safety and tolerability of the investigational drug, MRG-201, in healthy volunteers.
- Trial name
- NCT02603224
- Testing
- MRG-201
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- miRagen Therapeutics, Inc.
Diabetic Kidney Disease
Study to Evaluate the Pharmacokinetics of Selonsertib in Participants With Normal and Impaired Hepatic Function
The primary objective of this study is to evaluate the pharmacokinetics (PK) of selonsertib in participants with impaired hepatic function relative to matched, healthy controls.
- Trial name
- NCT02509624
- Testing
- Selonsertib
- Where
- 5 sites in United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Gilead Sciences
Breast Neoplasms
Breast Cancer and Exercise Trial in Alberta
The Breast Cancer and Exercise Trial (BETA Trial) is a randomized controlled trial aimed at understanding what dose (or volume) of exercise will best reduce the risk for breast cancer, particularly among women who are between the…
- Trial name
- BETA (NCT01435005)
- Testing
- Moderate Volume, High Volume
- Where
- 2 sites in Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- AHS Cancer Control Alberta
Blood Pressure
Accuracy Study of a Non-Invasive Blood Pressure Cuff in Comparison to an Invasive Radial Arterial Blood Pressure
The purpose of this study is to establish the performance of a blood pressure cuff. The hypothesis is that the blood pressure reading from the cuff will provide similar blood pressure as a radial artery.
- Trial name
- NCT01485120
- Testing
- BP monitoring using two methods
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Healthy, Stroke
Influence of Brain Oscillation-Dependent TMS on Motor Function
Background: When people have a stroke, they often have difficulty moving their arms and hands. Transcranial magnetic stimulation (TMS) can improve how well people with and without stroke can move their arms and hands.
- Conditions
- Healthy, Stroke, Normal Physiology, Aging
- Trial name
- NCT03288220
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Breast Cancer
Study to Examine the Effect of HKI-272 on Rhythms of the Heart (Cardiac Repolarization)
The purpose of this study is to determine whether HKI-272 affects the rhythms of the heart (cardiac repolarization).
- Trial name
- NCT00708903
- Testing
- neratinib, Moxifloxacin
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Puma Biotechnology, Inc.
Acne
Clinical Study for the Evaluation of P-3075 Cream on Acne Treatment
Primary end point of the study is the clinical and non-invasive instrumental evaluation of the activity of P-3075 cream on subjects with acne: 20 subjects with a mild/moderate grade and 20 subjects with a moderately severe/severe…
- Trial name
- ANTI-ACNE (NCT01948570)
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Derming SRL
Male Pattern of Hair Loss, Androgenic Alopecia, Androgenetic Alopecia (AGA)
Phase I Clinical Trial of CG2001 in Chinese Adult Male Participants With Androgenetic Alopecia
This study is testing CG2001, a new medicine that is applied as a light foam to the scalp and is being developed to treat male-pattern hair loss (androgenetic alopecia). The main goals are to find out: 1.
- Trial name
- NCT07038941
- Testing
- CG2001
- Where
- China
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Beijing Dayspring Pharmaceutical Technology Co., Ltd
Diabetic Foot, Diabetic Foot Ulcer
SkinTE™ in the Treatment of Diabetic Foot Wounds
This study is a prospective, multi-center, randomized controlled trial designed to collect patient outcome data on a commercially available human autologous homologous skin construct with SOC dressing compared to SOC dressings…
- Conditions
- Diabetic Foot, Diabetic Foot Ulcer, Ulcer Foot
- Trial name
- NCT03881254
- Testing
- Human Autologous Homologous Skin Construct, Additional Outer Dressing Applicaiton, Offloading
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- PolarityTE
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