Clinical trials: Normative
Healthy Subjects
Definition and Validation of Normative Data of EndoFLIP™ Measurements in Healthy Subjects
Multicenter, Prospective, Non-Randomized clinical trial to define and validate normative data of EGJ-distensibility measurements and contractile patterns in healthy subjects.
- Trial name
- RUBY (NCT03831724)
- Testing
- EndoFLIP™ System with FLIP Topography Module
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medtronic - MITG
All Health Backgrounds to Determine a Baseline of Flatus Activity
Using the Smart Underwear Device to Determine a Baseline of Flatus Activity Normalized to Fiber Intake
The goal of this observational study is to quantify the typical frequency of flatulence in healthy adults, normalized by fiber intake, using the Smart Underwear device.
- Trial name
- NCT07134543
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Cerebral Palsy, Infant Development
Neuroimaging of Babies During Natural Sleep to Assess Typical Development and Cerebral Palsy
Background: Early diagnosis of cerebral palsy (CP) is crucial, enabling intervention when neuroplasticity is at its highest. Magnetic resonance imaging (MRI) plays a vital role in CP diagnosis.
- Conditions
- Cerebral Palsy, Infant Development, Development, Infant
- Trial name
- NIBS-CP (NCT06396520)
- Testing
- No intervention, observational
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Danish Research Centre for Magnetic Resonance
Muscle Strength, Healthy
Reference Equations and Normative Data for Isometric Quadriceps and Handgrip Muscles STrength in Southern European Populations - RESTart: a Multicentre Study
This observational study aims to learn about peripheral muscle strength in healthy adults and people with chronic respiratory diseases.
- Conditions
- Muscle Strength, Healthy, Chronic Respiratory Diseases
- Trial name
- RESTart (NCT07628530)
- Where
- Spain
- Volunteers
- 2,815 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Perinatal Depression, Perinatal Anxiety
Effectiveness and Implementation of a Personalized mHealth Intervention for the Universal Prevention of Maternal Perinatal Mental Disorders
This study is part of the ERC-funded e-Perinatal project and represents a large-scale hybrid type 1 effectiveness-implementation cluster randomized controlled trial.
- Trial name
- ePerinatal-RCT (NCT07613008)
- Testing
- The e-Perinatal intervention is a personalized mobile health (mHealth) program, Standard routine maternal care
- Where
- Spain
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Seville
Warfarin
Patient Self Testing of Warfarin Therapy
To test the hypothesis that home international normalised ratio (INR) monitoring with supervised patient self-testing (PST)can provide comparable or superior time in therapeutic range (TTR) to that provided by traditional…
- Trial name
- NCT00594828
- Testing
- CoaguChek (Patient self testing), Anticoagulation Management Service (AMS)
- Where
- Ireland
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- University College Cork
Healthy, Heart Valves
Assessment of a Diagnostic Medical Device for the INR (International Normalized Ratio) Measurement
The purpose of this study is to assess the measurement conformity of an in vitro diagnostic device measuring the INR (International harmonized Ratio).
- Conditions
- Healthy, Heart Valves, Arrhythmias, Cardiac, Thromboembolism
- Trial name
- HEMOPTICS2 (NCT02779400)
- Testing
- Self testing INR device
- Where
- France
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Coordination Disorder, Developmental
Normative Reference Values of Equilibrium Coordination Test Among Children
A cross-sectional study will be conducted recruiting children of age group 8-15 years. Pilot study has been conducted for the determination of the sample size.
- Trial name
- NCT05159297
- Testing
- Reference values
- Where
- India
- Volunteers
- 1,104 people, healthy volunteers welcome
- Sponsor
- Asir John Samuel
Most Demanding Periods, Sport
The Most Demanding Match Periods: Should GPS Data be Normalized
To date, the characterization of Most Demanding Periods (MDPs) in soccer has relied almost exclusively on absolute metrics, suggesting that the peak demands currently reported in the scientific literature are inherently shaped by…
- Trial name
- NCT07321496
- Testing
- Assessment of most demanding periods in soccer
- Where
- Portugal
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Maia
Dry Eye
Cyclosporine 0.1% / Loteprednol 0.2% Effect on Anterior Segment Normalization
The CLEAN Study: Cyclosporine 0.1% / Loteprednol 0.2% Effect on Anterior Segment Normalization-A Prospective Cohort Study of Combination Therapy in the Treatment of Dry Eye
- Trial name
- CLEAN (NCT05322148)
- Testing
- Klarity CL, Cylcosporine 0.1%/Loteprednol Etabonate 0.2% Preservative Free
- Where
- 3 sites in United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Research Insight LLC
Healthy Volunteer
Normal Values in Hearing and Balance Testing
Background: Researchers at the National Institutes of Health give many tests of hearing and balance. These tests can help detect problems that affect hearing or balance.
- Trial name
- NCT01629108
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Sleep Disorders
Pediatric Sleep Questionnaire: Normalization and Validation Study
The information gathered from normal pediatric patients seen at the Pediatric Neurology Clinic in the DCAM and LaRabida Children's Hospital will be used to standardize and validate the information gathered from pediatric patients…
- Trial name
- NCT00203840
- Where
- United States
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Pediatric ALL, Adolescent
Pediatric Normative Markerless Movement Analysis
The objective of this project is to collect baseline data from a normative population of 20 children that gender and age matches the population of patients expected to be treated by Mary Bridge Children's Research \& Movement Lab.
- Trial name
- NCT06249880
- Testing
- Observation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- MultiCare Health System Research Institute
Healthy
Normative State and Variation in Growth, Hematology, Hydration, Oxidation, Infection, Inflammation, Guatemalan Children
This study will provide the researchers with an opportunity for the investigation of the biomarkers and different human biology component variable interactions in children; information that can generate new correlations between…
- Trial name
- NCT02203890
- Where
- Guatemala
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- María José Soto
Healthy
Estimating Error in Locating Touch Sensation on Forearm in Healthy Middle School Going Children
Tactile localization stimuli are fundamental in forearm to the somatosensory perception.Tactile localization reverse the touch internal organization of the forearm and in the normal development of children.It is helpful in quick…
- Trial name
- NCT03546712
- Testing
- Tactile Localization
- Where
- 2 sites in India
- Volunteers
- 365 people, healthy volunteers welcome
- Sponsor
- Maharishi Markendeswar University (Deemed to be University)
HIV Testing, HIV Stigma
Personalized Normative Feedback to Increase HIV Testing
Randomized trial to measure the effect of personalized normative feedback about local HIV testing rates and local rates of HIV-related stigma on self-reported HIV testing intentions and perceptions about others' HIV testing…
- Trial name
- NCT06969677
- Testing
- Survey questionnaire
- Where
- Uganda
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Healthy, Speech Disorders
Development of Normative Ultrasound Databases of Tongue Surface Configuration
Our past ultrasound research has indicated a need for baseline normative tongue data against which to compare our disordered speech populations.
- Trial name
- NCT00001218
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Healthy Volunteers, Dynamic Stability Margin
Normative Dynamic & Magnetic Spine
This study aims to describe normal spinal musculoskeletal patterns in healthy adolescents and young adults by using static and dynamic measures.
- Conditions
- Healthy Volunteers, Dynamic Stability Margin, Gait, Paraspinal Muscles
- Trial name
- NDMS (NCT03125434)
- Testing
- EOS full-spine, MRI, gait analysis
- Where
- France
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Wrist, Reliability
Angle-Specific Torque Profile Analysis in the Wrist Joint
The wrist joint performs various tasks at multiple angles during daily activities, both in flexion and extension positions. Among the parameters that facilitate these tasks, strength-particularly in relation to coordination and…
- Conditions
- Wrist, Reliability, Torque, Isokinetic
- Trial name
- NCT07122375
- Testing
- Angle Specific Torque Profile Analysis
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gazi University
Gait
Normative Database for Gait Analysis on the GRAIL UZ Gent
The aim of this study is to collect a large set of norm/control data on an instrumented treadmill (the Gait Real-time Analysis Interactive Lab - GRAIL) at the university hospital of Ghent for the purpose of clinical studies as…
- Trial name
- B670201942108 (NCT04987346)
- Testing
- Walking on an instrumented treadmill, Walking on an instrumented treadmill while dual-tasking
- Where
- Belgium
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent