Clinical trials: OCT Angiography
Central Serous Chorioretinopathy
Optical Coherence Tomography Angiography (OCT-A) and Central Serous Chorioretinopathy (CSC)
Optical Coherence Tomography Angiography (OCT-A) is a noninvasive imaging technique that allows one to see blood vessels in the retina.
- Trial name
- OPACITY (NCT03950089)
- Testing
- Optical Coherence Tomography Angiography (OCT-A)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
SLE (Systemic Lupus)
Posterior Segment Evaluation of Patients With SLE Using OCT and OCTA
Aim of The Study To evaluate different structural retinal changes using OCT and OCT-A in patients with SLE ; newly diagnosed patients and patients on treatment and compare parameters with normal subjects
- Trial name
- NCT04866615
- Testing
- Optvue OCT
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Minia University
Healthy
Semi-manual Vessel Density Analysis on Optical Coherence Tomography Angiography Images of Healthy Adults
Purpose of the study is to examine the vessel density of healthy adults' optical coherence tomography angiography images with two semi-manual methods and an automated quantification program.
- Trial name
- NCT03590899
- Testing
- Optical coherence tomography angiography (Zeiss Cirrus HD OCT 5000 AngioPlex)
- Where
- Hungary
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Pseudophakic Cystoid Macular Edema
Optical Coherence Tomography Angiography and Pseudophakic Cystoid Edema
This study evaluates the retinal vascular features in macula and papillary regions in patients affected by pseudophakic cystoid edema using optical coherence tomography angiography
- Trial name
- NCT05117411
- Testing
- OCTA and pseudophakin cystoid edema
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Federico II University
Choroid, Retina
Effect of Different Intensities of Repeated Low-Level Red-Light Therapy on Choroidal and Retinal Blood Flow Among Adults
The purpose of this clinical trial is to evaluate the effect of different intensities of repeated low-level red-light (RLRL) therapy on the choroidal and retinal blood flow among adults.
- Trial name
- NCT05747742
- Testing
- RLRL device
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The Second People's Hospital of Foshan
Behçet's Disease
Relation Between Nail Fold Capillaroscopy, Optical Coherence Tomography Angiography, and Femoral Vein Wall Thickness in Behçet's Disease Relation Between Nail Fold Capillaroscopy, Optical Coherence Tomography Angiography, and Femoral Vein Wall Thickness in Behçet's Disease
Relation between Nail Fold Capillaroscopy, Optical Coherence Tomography Angiography, and Femoral Vein Wall Thickness in Behçet's Disease
- Trial name
- NCT06296004
- Testing
- Nail Fold Capillaroscopy, Optical Coherence Tomography Angiography, and Femoral Vein Wall Thickness by U.S
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Diabetic Retinopathy, Periodontitis
Periodontitis Severity in Patients With Diabetic Retinopathy
The aim of this observational study is to investigate the relationship between periodontal disease severity and retinal layer thickness in patients diagnosed with diabetic retinopathy (DR), using optical coherence tomography…
- Trial name
- NCT07137013
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Optical Coherence Tomography, Optical Coherence Tomography Angiography
Normative Database of Healthy Subject Vascular Density Using Spectralis Heidelberg® Optical Coherence Tomography Angiography
Optical coherence tomography angiography (OCT-A) is a determinant progress to study retinal and choroidal vasculature without using a dye injection.
- Trial name
- COPENBASE (NCT06043622)
- Testing
- Optical coherence tomography angiography, ophthalmological exam
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Alzheimer Disease, Amyloid Angiopathy
Comparison of OCTA Factors in Patients With or Without Amyloid Pathology: A Prospective Study
To compare alternation of retinal microcirculation within the macula and optic disc in patients with dementia, mild cognitive impairment (MCI), and cognitively healthy subjects who had positive amyloid biomarkers (Aβ +) or not…
- Conditions
- Alzheimer Disease, Amyloid Angiopathy, Macular Ischemia, Dementia
- Trial name
- NCT05475158
- Where
- South Korea
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Pusan National University Hospital
Amnesia, Alzheimer Disease
OCT-Angiography and Adaptive Optics in Patients With Memory Impairment
Studies suggest an association between retinal abnormalities and NCD (Neuro Cognitive Disorders) whether they are linked to proven or prodromal Alzheimer's disease (aMCI : amnestic mild cognitive impairment), or to other…
- Conditions
- Amnesia, Alzheimer Disease, Lewy Body Disease, Parkinsons Disease With Dementia
- Trial name
- OCTAVO (NCT04389437)
- Testing
- Ophthalmological exam, Blood pressure measurement
- Where
- France
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Patients With Cardiovascular Disease, Healthy Participants
OCTA in Cardiovascular Disease and Healthy Controls
This prospective clinical study will involve the non-invasive assessment of retinal vessels using OCTA (Cirrus OCT 6000 AngioPlex) and scanning laser Doppler flowmetry (SLDF) in patients with cardiovascular disease and healthy…
- Trial name
- NCT07359664
- Testing
- Retinal vascular assessment using OCTA and SLDF
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Retinal Vascular
Physiologic Changes of Posterior Ocular Segment During the Menstrual Cycle
Changes of luteinizing hormone (LH), estrogen and progesterone during the menstrual cycle influence the ocular physiology in both anterior and posterior segments.
- Trial name
- NCT04731207
- Testing
- Optovue®
- Where
- Thailand
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Myopia
Optical Coherence Tomography Angiography in Myopic Patients
The aim of this study is to investigate the macular microvascular network alterations in high myopic eyes using optical coherence tomography angiography.
- Trial name
- NCT04135209
- Testing
- Optical coherence tomography angiography OCTA
- Where
- Egypt
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Minia University
Retinal Vascular, Normal Eyes
Evaluation of Heidelberg Engineering SPECTRALIS With OCT Angiography Module
Assessment of image quality and clinical relevance of OCT Angiography via comparison to FA/ICGA.
- Trial name
- NCT03279939
- Testing
- OCT Angiography, Color Fundus Photography, Fluorescein Angiography
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Heidelberg Engineering GmbH
Pregnancy Related
Retinal and Choroidal Microvascular Changes During Pregnancy Period Detected With Optical Coherence Tomography Angiography
During pregnancy many physiological changes and adaptations occur.Hormonal, hematological and hemodynamic changes are responsible for most of the ocular adaptations.We are planning to compare the choroid and retinal blood flow…
- Trial name
- NCT04950855
- Testing
- Optical Coherence Tomography,Optical Coherence Tomography Angiography(Topcon)
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Glaucoma
To Evaluate the Effect of Ginkgo Biloba Extract on Optic Nerve Head Perfusion Examined Using OCTA
Glaucoma is defined as progressive neuropathy of the optic nerve. It is an important cause of irreversible blindness worldwide. Lowering the intraocular pressure is the only proven treatment for this neurodegenerative disease.
- Trial name
- GBE (NCT04846179)
- Testing
- Ginkgo biloba extract
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Retinal Vein Occlusion, Vascular Occlusive Disease
Intravitreal Aflibercept for Macular Edema Due to Central Retinal Vein Occlusion
Central retinal vein occlusion (CRVO) is a common retinal vascular disorder, occurring when there is a blockage to the main blood vessel that transports blood away from the retina.
- Trial name
- INTRAMED-CRVO (NCT06416241)
- Testing
- EYLEA 2 MG in 0.05 ML Injection
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Athens
Retina Condition Followed by Fluorescein Angiography Imaging
OCT Angiography Software Evaluation Study
Comparisons for vascular structure visualization in the retina and choroid.
- Trial name
- NCT04701931
- Testing
- Maestro2 OCTA, Cirrus HD-OCT 5000, TRC-50DX
- Where
- 2 sites in United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Topcon Corporation
Alzheimer Disease, Dementia
OCT Angiography and NRAI in Dementia
The primary goals of this study are to use optical coherence tomography (OCT) angiography (blood vessel mapping) to: 1. Detect retinal blood vessel and blood flow changes in participants with dementia. 2.
- Conditions
- Alzheimer Disease, Dementia, Mild Cognitive Impairment
- Trial name
- NCT03761381
- Testing
- Optical Coherence Tomography Angiography (OCTA) Imaging, Noninvasive Retinal Amyloid Imaging (NRAI)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Cataract, Diabetic Retinopathy
Diabetic Retinopathy and OCT-A Changes Post-cataract Surgery
The purpose of this study is to use optical coherence tomography angiography (OCT-A) to compare retinal vasculature after uncomplicated cataract surgery in patients with and without diabetic retinopathy.
- Conditions
- Cataract, Diabetic Retinopathy, Macular Edema Due to Diabetes Mellitus
- Trial name
- NCT04660006
- Testing
- Cataract surgery
- Where
- Canada
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Uptown Eye Specialists