Clinical trials: Observation
Neurosciences
The Brain Activation During Different Motor Patterns in Healthy Adults
This study aims to investigate the brain activation during different motor patterns, including motor execution (ME), motor imagery (MI), action observation (AO) and mirror visual feedback (MVF).
- Trial name
- NCT04868929
- Where
- Taiwan
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Diabete Mellitus, Pre-diabetes
Investigating the Syndrome Differentiation of Diabetic and Pre-diabetic Using Digitalized TCM Diagnostic Tools
The investigators aim to objectively identify the Traditional Chinese Medicine (TCM) syndrome differentiation of type II diabetic and prediabetic patients in Singapore through modern technologies thereby potentially increasing…
- Conditions
- Diabete Mellitus, Pre-diabetes, Healthy, Hypertension
- Trial name
- NCT05563090
- Testing
- Questionnaires+Tongue diagnosis+Pulse diagnosis
- Where
- Singapore
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Singapore Chung Hwa Medical Institution
Macrosomia, Induction of Labor
Induction of Labor Versus Expectant Management of Large for Gestational Age/Macrosomic Babies at Term. A Multi-center Trial
The equipoise whether to Induce pregnant women with suspected large for gestational babies or suspected macrosomia babies at term pregnancy is not solved yet.
- Conditions
- Macrosomia, Induction of Labor, Expectant Management, Shoulder Dystocia
- Trial name
- IOLEMMT (NCT02315820)
- Testing
- Induction of labor group (Group I)
- Volunteers
- 474 people, healthy volunteers welcome
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Autism, Autism Spectrum Disorder
Online Evaluation of the Diagnostic Accuracy of BlinkLab's Digital Assessments for Autism
This observational study aims to evaluate how patterns of behavioral and sensorimotor responses measured using the BlinkLab Dx1 smartphone application relate to autism diagnoses in children ages 2 to 11.
- Conditions
- Autism, Autism Spectrum Disorder, Autism Spectrum Disorder (ASD), Neurodevelopmental Conditions
- Trial name
- NCT07590973
- Testing
- BlinkLab Dx1, Retrospective Neurodevelopmental Diagnostic Assessment
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Blinklab Limited
NSCLC
18F-FDG PET/CT to Evaluate pD-1 Monoclonal Antibody With First-line Chemotherapy in Advanced NSCLC
This study is a diagnostic study. Subjects were enrolled from clinical stage IIIB or IV NSCLC patients who received standard first-line chemotherapy combined with PD-1 monoclonal antibody immunotherapy and received 18F-FDG PET/CT…
- Trial name
- NCT04996927
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Transient Ischemic Attack
Transient Ischemic Attack (TIA) Accelerated Diagnostic Protocol
The primary objective of this study is to determine if emergency department patients with Transient Ischemic Attack (TIA) that are managed using a TIA "accelerated diagnostic protocol", or "ADP", demonstrate a significant…
- Trial name
- NCT00321022
- Testing
- Accelerated Diagnostic Protocol Emergency Department Observational Unit
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Corewell Health East
Self Efficacy
Telesimulation and Behavioral Health
This study proposes to assess attitudes, perceived proficiency, and knowledge related to telemedicine by implementing telesimulation behavioral health scenarios in a cohort of healthcare students using the Contextual Interview…
- Trial name
- NCT03661372
- Testing
- Robot, Face-to-face
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Pacific Northwest University of Health Sciences
Healthy Volunteers
The Effect of Phenylephrine and Ephedrine on Microvascular Blood Flow
During operations to treat abdominal problems the blood pressure can fall, resulting in falls in blood flow to the vital organs. This fall can be treated by the administration of drugs that cause constriction of blood vessels.
- Trial name
- NCT02252627
- Testing
- Administration of phenylephrine, Measurement of stroke volume, Contrast enhanced ultrasound scan
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Hypertension, Cardiovascular Risk Factors
Community Blood Pressure Screening and Cardiovascular Risk Assessment in Croatia
This is a prospective, observational, non-interventional study conducted during community-based public health blood pressure screening campaigns in Croatia.
- Trial name
- BPSCREEN-CRO (NCT07670741)
- Testing
- Blood pressure measurement and questionnaire-based data collection
- Where
- Croatia
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Dr. Josip Benčević General Hospital
Hepatitis, Delta
Patient Knowledge, Beliefs and Barriers to Hepatitis D Care
A project to understand the determinants of health behaviour among those with chronic hepatitis D virus (HDV) infection, under the care of the viral hepatitis service at Kings College Hospital (KCH).
- Trial name
- NCT06017375
- Testing
- Questionnaire based intervention
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- King's College Hospital NHS Trust
Apnea, Obstructive Sleep, Obesity
Association of Body Fluid Distribution With Obstructive Sleep Apnea in Pregnant Women With Body Mass Index ≥ 40 kg/m2
Obstructive Sleep apnea (OSA) is a common and underdiagnosed condition in obese pregnant women with serious and life-threatening complications to the mother and baby.
- Trial name
- NCT04187612
- Testing
- Bioelectrical Impedance Analysis (BIA)
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Genetic Conditions
Observational Study of Advanced Data Analytics in Genetic Conditions
Background: The genes a person is born with can sometimes cause serious diseases. Genetic diseases are rare, but they can have a big impact on the people they affect.
- Trial name
- NCT05657405
- Where
- United States
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- National Human Genome Research Institute (NHGRI)
Internal Carotid Artery Stenosis
The Observation About the Effects of Internal Carotid Artery Stenosis on Fundus Vessels and the Changes of Fundus Vessels After Interventional Therapy
The investigators plan to collect 30 participants with internal carotid artery stenosis to observed the relationship between the degree of internal carotid artery stenosis and fundus vessels （and blood flow）density before…
- Trial name
- NCT05260229
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Psychological Distress
Psychological Distress in Emerging Adulthood: A Longitudinal Study
Emerging adulthood (18-29 years) is a critical stage in lifespan development. During this stage, people experience instability: shifts from their families of origin, breakups of relationships and job changes are frequent before…
- Trial name
- DistressEA (NCT04596345)
- Where
- Ecuador
- Volunteers
- 1,168 people, healthy volunteers welcome
- Sponsor
- Universidad de las Americas - Quito
Shock, Sepsis
Surrogate of Adequate Perfusion: Bladder Tissue Oxygen Monitoring
The extent and duration of tissue hypoxia is a major determinant of outcome following major, high-risk surgery and in critical illness.
- Conditions
- Shock, Sepsis, Surgery
- Trial name
- SoAP-BOx (NCT03935477)
- Testing
- WellBeing catheter
- Where
- United Kingdom
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- University College London Hospitals
Fatigue Intensity, Sleep
MorphECOS - Evaluation of the Influence of Fatigue and Sleep on the Performance of 2nd Cycle Medical Students (OSCE)
Objective and Structured Clinical Examinations (OSCEs) has been incorporated recently in the certification process as a final national undergraduate ranking examination. This exam is a challenge for medical students.
- Conditions
- Fatigue Intensity, Sleep, Sleep Deprivation, Circadian Rhythm
- Trial name
- MorphECOS (NCT06952972)
- Where
- France
- Volunteers
- 619 people, healthy volunteers welcome
- Sponsor
- Claude Bernard University
Acute Pain
Vasopressin and Pain Perception in the Brain
The feeling of pain is not just a sensory experience, but is also influenced by emotions, beliefs and expectations, making pain a highly subjective experience.
- Trial name
- NCT03446456
- Testing
- Arginine vasopressin, Saline, Observational learning
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
SARS-CoV2 Infection
Understanding the Long-term Impact of COVID-19 in Adults (RECOVER)
This is a combined retrospective and prospective, longitudinal, observational meta-cohort of individuals who will enter the cohort with and without SARS-CoV-2 infection and at varying stages before and after infection.
- Trial name
- NCT05172024
- Where
- 86 sites in United States, Puerto Rico
- Volunteers
- 15,172 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
HIV Infections, HIV-1-infection
Prospective Observational Cohort HIV & STI Study in Europe
The University Hospital Essen is sponsoring the Multicenter human immunodeficiency virus (HIV) and sexually transmitted infections Prevention Network Study (STIPnet) which is funded by Janssen, Pharmaceutical Companies of Johnson…
- Conditions
- HIV Infections, HIV-1-infection, Risk Reduction, Sexual Behavior
- Trial name
- NCT03866759
- Testing
- Determine the Incidence and Point Prevalence
- Where
- 15 sites in France, Hungary and 3 more
- Volunteers
- 3,593 people, healthy volunteers welcome
- Sponsor
- Hendrik Streeck
Pain Management, Analgesia
Post-Operative Pain Management Following Spine Surgery
The primary objective of this pilot study is to assess the feasibility of comparing two standardized approaches to manage post-operative pain following spine surgery: one approach using Patient Controlled Analgesia (PCA) devices…
- Conditions
- Pain Management, Analgesia, Anesthetic
- Trial name
- EXPAREL (NCT03076710)
- Testing
- Opioids delivered through PCA, EXPAREL® infiltration
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
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