Clinical trials: Occupational Exposure, active
Skin Cancer, Heat Tolerance
Title: ICARUS - Psycho-physiological Profiling of Low and High Heat-resilient Individuals
The escalating environmental heat-stress associated with global warming is a societal challenge with large and potential harmful consequences for humans.
- Conditions
- Skin Cancer, Heat Tolerance, Heat-related Illness, Hyperthermia
- Trial name
- ICARUS (NCT07510061)
- Testing
- Controlled Heat and Ultraviolet Radiation Exposure Protocol
- Where
- 2 sites in Denmark, Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Musculoskeletal Disorder, Anxiety Disorders
A Multicentre Randomised Controlled Trial of the Norwegian Health in Work Service. The NSAC Efficacy Study
The Norwegian Sickness Absence Clinic (NSAC) is a publicly funded specialist outpatient health service, which is uniquely available for the work force.
- Conditions
- Musculoskeletal Disorder, Anxiety Disorders, Depression, Fatigue
- Trial name
- NSAC (NCT05310695)
- Testing
- NSAC - rapid, NSAC - ordinary, NSAC - active control
- Where
- 5 sites in Norway
- Volunteers
- 2,500 people
- Sponsor
- Nordlandssykehuset HF
Interstitial Lung Disease Due to Systemic Disease (Disorder), Interstitial Lung Disease Due to Systemic Disease (Telomere Biology Disorder)
Occupational and Environmental Exposures Analysis in Interstitial Lung Diseases.
The OCEAN-ILD study is designed to prospectively evaluate the prevalence and clinical relevance of environmental and occupational exposures in a large Italian cohort of patients affected by any ILD, using a standardised exposure…
- Conditions
- Interstitial Lung Disease Due to Systemic Disease (Disorder), Interstitial Lung Disease Due to Systemic Disease (Telomere Biology Disorder), Exposure Occupational, Occupational Exposure
- Trial name
- OCEAN-ILD (NCT07577115)
- Testing
- standard interview
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Istituto Clinico Humanitas
Occupational Exposure to Radiation, Neoplasms, Radiation-Induced
Epidemiological Study of Korean Radiation Workers
Health risks of radiation exposure in the moderate-to-high dose range have been well established. However, the risk remains unclear at low-dose ranges with protracted low-dose rate exposure, which is typical of occupational…
- Conditions
- Occupational Exposure to Radiation, Neoplasms, Radiation-Induced, Leukemia, Radiation-Induced, Radiation Effects
- Trial name
- KRWS (NCT05380570)
- Testing
- Occupational radiation exposure
- Where
- South Korea
- Volunteers
- 196,379 people
- Sponsor
- Korea Institute of Radiological & Medical Sciences
Formaldehyde, Pathological Anatomy and Cytology
Experimentation of Formaldehyde Purification by Plants in the Anatomy and Cytology Department
Formaldehyde is notably used as a tissue fixator in pathological anatomy. Despite its toxicity, it continues to be widely used because it is currently not substitutable.
- Trial name
- DETOXANAPATH (NCT07264504)
- Testing
- Biological measurement of urinary formic acid, Plant installation
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Occupational Exposure
Unloading Maneuvers During Spinal Flexion Exposure
An experimental study, which will aim to investigate the acute effects of unloading maneuvers during an intermittent spinal flexion protocol on changes in trunk mechanical and neuromuscular properties.
- Trial name
- NCT07116720
- Testing
- Unloading maneuvers
- Where
- Slovenia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Occupational Radiation Exposure in Operating Room Nurses
PMT-Based Radiation Safety Training for Nurses: Randomized Controlled Trial.
This randomized controlled trial aims to evaluate the effect of a Protection Motivation Theory (PMT)-based radiation protection training program on nurses' knowledge, awareness, motivation, and safety behaviors.
- Trial name
- NCT07128407
- Testing
- Protection Motivation Theory-Based Radiation Protection Training
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Auditory Diseases, Central
Comparing Hearing Aid Fitting Methods in Blast-exposed Veterans
Since 2000, at least 250,000 U.S. Service members have experienced a blast-related mild traumatic brain injury. A retrospective analysis of over 100,000 post-9/11 Veterans shows that blast injury more than doubles the risk of a…
- Trial name
- SBA (NCT06309264)
- Testing
- Phonak Lumina P90
- Where
- 3 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
PFAS, Environmental Exposures
Use of Bile Acid Binding Resins to Decrease PFAS Levels Via Colesevalem in Veterans Study
The goal of this study is to test the efficacy and feasibility of Colesevelam administration (50% of the recommended dose) to reduce serum PFAS concentration in the Veteran population who have serum PFAS levels that exceed the…
- Conditions
- PFAS, Environmental Exposures, Occupational Exposure to Chemicals, Military Exposure
- Trial name
- PAVERS (NCT07592858)
- Testing
- Colesevelam
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Rhode Island
Work-Related Musculoskeletal Disorders, Ergonomic Risk Exposure
Posture Protection Program for Musculoskeletal Disorders and Ergonomic Risk in Hospital Cleaning Staff
Cleaning work, particularly in hospital settings, is an occupation that demands high physical load on both the musculoskeletal and cardiovascular systems.
- Trial name
- POSKOP (NCT07590453)
- Testing
- Posture Protection Program
- Volunteers
- 60 people
- Sponsor
- Akdeniz University
Job Satisfaction, Bullying, Workplace
Mobbing Exposure and Job Satisfaction Among Physiotherapists
Physiotherapists, who hold a significant place in the healthcare sector, are at risk for mobbing and low levels of job satisfaction due to both demanding physical working conditions and emotional stress.
- Trial name
- NCT07402824
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Spine Health, Spine Injuries and Disorders
Occupational Exposure to Whole Body Vibration Among U.S. Military Veterans: Acute and Chronic Contributions to Musculoskeletal Disorders and Spine-Area Pain
Significance to VA: There is a lack of prospective longitudinal studies investigating the relationship between risk factors to Veterans and development and progression of musculoskeletal (MSK) spine injury and pain.
- Conditions
- Spine Health, Spine Injuries and Disorders, Spine Degeneration, Whole Body Vibration
- Trial name
- NCT07367139
- Testing
- Water
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Milwaukee VA Medical Center
Aging, Mortality
Human Observatory Study
The Human Observatory Study is a prospective observational and ecological surveillance study building a continuously-updating world model for human health, disease, and death at the individual and population level.
- Conditions
- Aging, Mortality, All-cause Mortality, Life Expectancy
- Trial name
- HOS (NCT07646782)
- Testing
- Multi-Domain Ecological and Clinical Data Linkage
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Sharps Injuries, Needlestick Injuries
AI-Supported Gamified Training for Sharps Injury Prevention in Nurses
This study aims to evaluate the effect of a Health Belief Model (HBM)-based, artificial intelligence (AI)-supported gamified training program on nurses' knowledge and attitudes toward the prevention of sharps injuries.
- Conditions
- Sharps Injuries, Needlestick Injuries, Occupational Exposure
- Trial name
- NCT07562867
- Testing
- Experimental: Intervention Group, control group
- Volunteers
- 36 people
- Sponsor
- Baskent University
Skin Melanoma, Cutaneous Melanoma
Melanoma of the Skin and Exposure to Solar Ultraviolet Radiation at Work in Modena Territory: a Case-control Study to Promote an Active Search and Prevention of Occupational Diseases Based on Recent INAIL Criteria
The goal of this observational study is to learn about the link between work-related sun exposure and a specific type of skin cancer called melanoma in people living in the Modena area, Italy.
- Trial name
- Mesur (NCT07251335)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University of Modena and Reggio Emilia
Screen Time Exposure
The Effects Of Occupation-Based Self-Regulation Program On Sensory Processing, Executive Functions and Occupational Performance In Preschool Children With Screen Addiction
The purpose of this interventional study was to measure the effectiveness of a self-regulation program for screen addiction in preschool children aged 4-5 years.
- Trial name
- NCT07004036
- Testing
- Occupation-based Self-Regulation Intervention Program, Family Awareness Training
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Biliary Tract Cancer, Pancreatic Cancer
Study of Occupational Risk Factors for Biliary and Pancreatic Cancers
PANTOXBIL is a research project developed in the context of the increasing incidence of biliary tract and pancreatic cancers in France. Despite recent therapeutic advances, the prognosis of these cancers remains poor.
- Trial name
- PANTOXBIL (NCT07668024)
- Volunteers
- 210 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Glioblastoma
Key Longitudinal Associations With Risk and Glioblastoma Outcomes
The goal of this observational study is to find out what factors affect the health and risks in adults with glioblastoma (GBM), a grade 4 brain cancer.
- Trial name
- Key LARGO (NCT06625684)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Duke University
Microvascular Dysfunction, Endothelial Dysfunction
Nailfold Capillaroscopy and Endothelial Biomarkers in Healthcare Workers Exposed to Chronic Low-Dose Ionizing Radiation
Chronic occupational exposure to low-dose ionizing radiation may lead to subclinical endothelial dysfunction and early microvascular alterations in healthcare workers.
- Conditions
- Microvascular Dysfunction, Endothelial Dysfunction, Occupational Radiation Exposure
- Trial name
- NCT07363187
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul Training and Research Hospital
Body Temperature Changes, Heat Stress
Progressive Heat Exposure and Physiological Strain
Occupational heat-stress guidelines are commonly based on the level of environmental heat exposure and are largely derived from studies conducted under constant environmental conditions.
- Conditions
- Body Temperature Changes, Heat Stress, Heat Exposure, Heat Fatigue
- Trial name
- NCT07847437
- Testing
- Constant Heat Exposure, Progressively Increasing Heat Exposure
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Ottawa