Clinical trials: Ocular Injury
Eye Trauma
Playtime Open Globe Injuries in Children
This study investigated the epidemiology, aetiologies, and complications of playtime open-globe injuries in children at the Assiut University Hospital, Egypt, between January to July 2016.
- Trial name
- NCT04497896
- Testing
- Repair of open globe injury
- Volunteers
- 81 people
- Sponsor
- Assiut University
Glaucoma
NSAID vs Steroid in Trabeculectomy Wound Management
This study will examine the efficacy of steroid vs NSAID treatment in relation to trabeculectomy wound management. Eligible study participants will be randomized to receive either steroid or NSAID topical treatment one week…
- Trial name
- NCT03751059
- Testing
- Bromfenac 0.07% Oph Susp, Dexamethasone
- Volunteers
- 150 people
- Sponsor
- Cindy Hutnik
Mild Traumatic Brain Injury, Photophobia
Pilot Study of Neurofeedback for Photosensitivity in Mild Traumatic Brain Injury
The goal of this study is to complete a pilot study testing the feasibility and acceptability of low-intensity pulse-based transcranial stimulation (LIP-tES) neurofeedback intervention for reducing photosensitivity symptoms in…
- Trial name
- NCT06109909
- Testing
- Micro Current Neurofeedback Device using Low-Frequency Pulse-Based Transcranial Electrical Stimulation
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Burn
Comparing the Use of Vitamin c (Ascorbic Acid) in Eye Burn in Subconjunctival Injection to Topical or Oral Treatment.
Eye burns may cause a severe permanent damage. One kind of treatment is the use of vitamin C (Ascorbic acid). This study will compare between subconjunctival topical and/or systemic route of administration and topical and/or…
- Trial name
- NCT00734695
- Testing
- vitamin c
- Where
- 2 sites in Israel
- Volunteers
- 20 people
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Diabetic Retinopathy (DR), Macular Edema (ME)
Video Intervention to Improve Understanding of Diabetic Retinopathy at Zuckerberg San Francisco General Hospital and Trauma Center
The study will evaluate whether videos can improve understanding of diabetic eye disease, and follow-up rates in the eye clinic.
- Trial name
- NCT07519707
- Testing
- Animated Videos
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of California, San Francisco
Traumatic Brain Injury, Rebound Intracranial Hypertension
ONSD Trajectory in Rebound ICH
The goal of this prospective observational study is to determine whether the trajectory of optic nerve sheath diameter (ONSD) after osmotherapy weaning can predict rebound intracranial hypertension in adult patients with…
- Conditions
- Traumatic Brain Injury, Rebound Intracranial Hypertension, Cerebral Edema
- Trial name
- ONSD/ INH (NCT07722702)
- Testing
- Optic Nerve Sheath Diameter Ultrasonography
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University
Traumatic Brain Injury
TCD and ONSD for Early Risk Stratification of Traumatic Brain Injury
This observational study aims to evaluate the combined use of transcranial Doppler (TCD) and optic nerve sheath diameter (ONSD) ultrasound for early risk stratification of adults with traumatic brain injury (TBI) presenting to…
- Trial name
- TCD-ONSD (NCT07820527)
- Testing
- Transcranial Doppler and Optic Nerve Sheath Diameter Assessment
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Mild Traumatic Brain Injury, Vestibular Neuropathy
Incremental Velocity Error as a New Treatment in Vestibular Rehabilitation
The objective for this study is to compare outcome measures from vestibular rehabilitation (VPT) delivered in a traditional method against a new device Incremental Velocity Error (IVE) that improves physiologic performance of the…
- Trial name
- INVENT (NCT03846830)
- Testing
- Incremental Velocity Error (IVE), Traditional Vestibular Rehabilitation (VPT)
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Johns Hopkins University
HIV Infected Individuals
Piloting Eye Movement Desensitization and Reprocessing (EMDR) Therapy in People Living With HIV and Trauma
Eye Movement Desensitization and Reprocessing therapy is a time-limited trauma-response therapy that treats symptoms of stress that result disturbing life experiences.
- Trial name
- NCT06730867
- Testing
- EMDR Therapy Protocol
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Vanderbilt University Medical Center
Cancers, Cardiovascular Diseases
Swedish Mammography Cohort
The Swedish Mammography Cohort began in 1987-1990, when 66,651 women living in two counties in central Sweden completed a mailed questionnaire that included items about their diet, parity, age at first child's birth, history of…
- Conditions
- Cancers, Cardiovascular Diseases, Cataract, Gastrointestinal Diseases
- Trial name
- SMC (NCT01127698)
- Volunteers
- 61,433 people
- Sponsor
- Karolinska Institutet
Retinal Disease, Macular Degeneration
Stem Cell Ophthalmology Treatment Study
This study will evaluate the use of autologous bone marrow derived stem cells (BMSC) for the treatment of retinal and optic nerve damage or disease. http://mdstemcells.com/scots-ii/
- Conditions
- Retinal Disease, Macular Degeneration, Hereditary Retinal Dystrophy, Optic Nerve Disease
- Trial name
- SCOTS (NCT01920867)
- Testing
- RB (Retrobulbar), ST (Subtenon), IV (Intravenous)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- MD Stem Cells
Enucleated; Eye, Evisceration; Operation Wound
Retrobulbar Block Versus Ketamine Infusion for Post-enucleation Analgesia
This study compares the efficacy and safety of two techniques, retrobulbar block versus intra-operative ketamine infusion, for control of post-operative pain occurring in patients undergoing ocular enucleation or evisceration…
- Conditions
- Enucleated; Eye, Evisceration; Operation Wound, Pain, Postoperative
- Trial name
- NCT03507426
- Testing
- Retrobulbar block, Ketamine
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Nazmy Edward Seif
Irregular; Contour of Cornea, Keratoconus
Scleral Versus Corneal RGP Contact Lenses in Irregular Cornea Disorders
The most common causes for irregular cornea (IC) in hospital contact lens practice are Keratoconus (KC) and related cornea thinning disorders.
- Conditions
- Irregular; Contour of Cornea, Keratoconus, Pellucid Marginal Corneal Degeneration, Injury of Cornea
- Trial name
- NCT02444923
- Testing
- Scleral rigid gas permeable contact lenses (SRGPcl) (Zenlens™), Corneal Rigid gas Permeable contact lenses (CRGPcl) (Rose K2)
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- London South Bank University
Pediatric Ocular Trauma
Pediatric Ocular Trauma in Minia Governate
The most common cause of unilateral blindness in pediatric age groups, especially in developing countries, is ocular trauma. The epidemiology of eye injuries varies in different parts of the world and different age groups and…
- Trial name
- NCT05538260
- Testing
- Repair of ocular trauma in children below 16 years old
- Where
- Egypt
- Volunteers
- 103 people
- Sponsor
- Minia University
Cytomegalovirus Retinitis, Acute Renal Failure
Pharmacokinetics of Cidofovir During Continuous Venovenous Hemofiltration
Cidofovir is an acyclic nucleotide analog with broad-spectrum antiviral activity against herpesviruses. Its potency in inhibiting HCMV has been shown in conventional in vitro studies.
- Trial name
- NCT01866397
- Testing
- Cidofovir pharmacokinetics
- Where
- Austria
- Volunteers
- 1 people
- Sponsor
- Medical University of Vienna
Diabetes Mellitus, Diabetic Retinopathy
Evaluation of Early Retinal Nerve Injury in Type 2 Diabetes Patients Without Diabetic Retinopathy
The object of this study is to investigate the damage to the retinal nerve fiber layer (RNFL) and ganglion cell complex layer (GCL+) in diabetic patients without retinal microangioma as detected by fundus fluorescein angiography…
- Conditions
- Diabetes Mellitus, Diabetic Retinopathy, Nerve Injury
- Trial name
- NCT03970161
- Testing
- routine ophthalmic examination
- Where
- China
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Corneal Diseases
Ocular Surface Disorders in Patients in Intensive Care Units, a Comparative Study of Three Preventive Approaches
60% of the patients hospitalized in intensive care and sedated suffer from insufficient inferior eyelid occlusion. Thus, they are at risk for corneal damage (estimated risk 20% to 57%).
- Trial name
- OCUREA2 (NCT02348242)
- Testing
- Aqueous Gel, Eyelid Occlusion Dressing, Artificial Tears
- Where
- France
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Wave Form Signals Coming From the Eye in a Healthy Cohort
Neuro-ocular Baselines in a Sports Setting
Rebion (Rebiscan, Inc) has developed a noninvasive, handheld device that uses retinal birefringence scanning (RBS) to rapidly assess eye fixation and retinal integrity in adults and children.
- Trial name
- KY (NCT03653936)
- Testing
- HITT device
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Rebiscan, Inc.
Posttraumatic Stress Disorders, Multiple Sclerosis
The Efficacy of EMDR in Patients With PTSD in Multiple Sclerosis
Multiple Sclerosis (MS) can be associated to many psychological symptoms. One of the most relevant is the experience of distress related to the disease, that can lead to the development of Post Traumatic Stress Disorder (PTSD).
- Trial name
- NCT01743664
- Testing
- EMDR, Relaxation
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- San Luigi Gonzaga Hospital
Evisceration, Ocular Trauma
Comparing Posterior Release Sclerotomy With Conventional Evisceration Surgery.
The primary objective of this interventional study is to compare posterior release sclerotomy in the scleral cup with conventional ball implantation during evisceration, focusing on intraoperative feasibility, postoperative…
- Conditions
- Evisceration, Ocular Trauma, Blind Painful Eye, Phthisis Bulbi
- Trial name
- NCT06962384
- Testing
- Posterior release sclerotomy, Conventional Ball Implantation
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Fayoum University Hospital