Clinical trials: Old Adults
COVID-19
Phase I Clinical Trial of a COVID-19 Vaccine in 18-60 Healthy Adults
The 2019 novel-coronavirus (2019-nCov) is the cause of a cluster of unexplained pneumonia that started in Hubei province in China.
- Trial name
- CTCOVID-19 (NCT04313127)
- Testing
- Recombinant Novel Coronavirus Vaccine (Adenovirus Type 5 Vector)
- Where
- China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- CanSino Biologics Inc.
Frailty, Old Age; Debility
The Effects of a Tele-health Program
Frailty is a state of being vulnerable and functional disable due to age-related decline of multiple physiological systems, and is often associated with higher risk of falls, institutionalization, hospitalization, disability…
- Trial name
- NCT05267444
- Testing
- Individualized motion-based interactive game program
- Where
- Hong Kong
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Older Adults (60 - 85 Years Old)
Effect of Exercise of Shoulder - Pelvic Coupling Pattern on Breathing Using Proprioceptive Technique
The purpose of this study is to determine the effects of proprioceptive neuromuscular facilitation scapula-pelvis coupling pattern exercise on Respiratory capacity and quality of life in elderly people aged 65 years or older and…
- Trial name
- NCT07442942
- Testing
- PNF combination of scapular and pelvic pattern intervention, Chest cages expansion exercises intervention
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Boung-hyoun Moon
Fall Injury, Fall
Does Participation in a Fall Preparedness Program Improve Fall Efficacy Among Older Adults
The purpose of this study is to determine if a fall preparedness program can reduce the fear of falling in older adults and subsequently improve their function and reduce falls with injury.
- Conditions
- Fall Injury, Fall, Falls (Accidents) in Old Age
- Trial name
- NCT06545539
- Testing
- Fall Preparedness Exercise Class
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Youngstown State University
Meningococcal Infections
Immunogenicity and Safety of Meningococcal Conjugate Vaccine (EG-MCV4) in Healthy Adults Aged 19 to 55 Years Old
Phase 2/3 study to evaluate immunogenicity and safety in healthy adult participants following a single dose administration of Meningococcal (groups A, C, W-135, and Y) conjugate vaccine
- Trial name
- NCT07204457
- Testing
- EG-MCV4, Menveo
- Where
- South Korea
- Volunteers
- 1,123 people, healthy volunteers welcome
- Sponsor
- EyeGene Inc.
COVID-19, Vaccines
Safety and Immunogenicity of COVID-19 Vaccine, AdCLD-CoV19-1
The immunogenicity and safety profiles of AdCLD-CoV19-1 (5.0×10^10 VP/dose) will be assessed for 1-dose or 2-dose regimen in SARS-CoV-2 seronegative healthy adults.
- Trial name
- NCT05520970
- Testing
- AdCLD-CoV19-1
- Where
- 4 sites in South Korea
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Cellid Co., Ltd.
Old Age, Family Members
The Chit-Chat Educational Intervention to Promote Advance Care Planning in the Community
The purpose of this study is to estimate the effect size of the Chit-Chat intervention on ACP engagement among family members of older adults with multi-morbidity.
- Trial name
- NCT06296719
- Testing
- Chit-Chat
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Rotavirus Infections, Rotavirus Vaccines
Safety and Immunological Efficacy of the Pentavalent Rotavirus Vaccine - Rota-V-Aid™ (Live Attenuated Oral, Freeze-dried) at Healthy Adults Aged 18 to 45 Years.
The purpose of the presented study was to evaluate the safety and immunological efficacy in preventing the rotavirus infection within a cohort of healthy subjects (target age of 18-45 years old) by using the pentavalent rotavirus…
- Trial name
- NCT05037435
- Testing
- The pentavalent rotavirus vaccine (live attenuated oral, freeze-dried)
- Where
- Russia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Limited Liability Company Pharm Aid
Typhoid Fever
Safety and Immunogenicity of Three Formulations of Vi-CRM197 Vaccine Against S. Typhi in Adults (18-40 Years Old)
This trial is aimed to evaluate the safety and immunogenicity profiles of three formulations of Vi-CRM197 conjugate vaccine against S.
- Trial name
- NCT01193907
- Testing
- NVGH Vi-CRM197 12.5 mcg, NVGH Vi-CRM197 5.0 mcg, NVGH Vi-CRM197 1.25 mcg
- Where
- Belgium
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Novartis
Mild Cognitive Impairment, Old Age; Debility
Dual Task Perturbation Training for OAwMCI
Studies have determined that compared to cognitively intact older adults (CIOA), older adults with mild cognitive impairment (OAwMCI) exhibit more pronounced balance and gait impairments which lead to an increased risk of falls…
- Trial name
- NCT04938349
- Testing
- Dual task perturbation training
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Cognitive Function, Depression in Old Age
Computer Presented and Physical Exercises to Maintain Cognitive Function and Emotional Health in Older Adults
The aim of this study is to investigate and compare how 18-weeks of computer-based brain training and physical exercise together can improve physical performance, cognitive function and mood in older adults in a cross-over design…
- Trial name
- NCT04404621
- Testing
- Physical exercise (PE) training and computer-based brain (CBB)
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Yale University
Falls (Accidents) in Old Age
Evaluating Technology-Based Fall Prevention Interventions
Approximately one in three older adults fall annually and it is the primary cause of traumatic injury in older adults. While exercise and balance programs have been shown to be effective in reducing fall risk, maintaining…
- Trial name
- FaCT2 (NCT03190460)
- Testing
- Cognitive Training, Technology-based Education
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Washington
Older Adults (65 Years and Older), INSTITUTIONAL CARE
ROLE OF DUAL-TASK COST IN PREDICTING FALL RISK AMONG OLDER ADULTS RECEIVING INSTITUTIONAL CARE
There is a need for studies that examine the role of dual-task cost in predicting fall risk among older adults receiving institutional care and that develop classification models that can be used in clinical practice.
- Conditions
- Older Adults (65 Years and Older), INSTITUTIONAL CARE, Dual Task Cost, Falls in Old Age
- Trial name
- NCT07631975
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Immunogenicity and Safety of a Recombinant Adenovirus Type-5-vectored COVID-19 Vaccine Using for Sequential Immunization
Sequential Immunization With Recombinant Adenovirus Type-5-vectored COVID-19 Vaccine in Health Adults Based on 3 Doses Inactivated COVID-19 Vaccine
COVID-19 is a novel coronavirus infection caused by respiratory droplets and contact transmission. With the spread of the epidemic, it has become a serious threat to global public health.
- Trial name
- NCT05373030
- Testing
- Recombinant adenovirus type-5-vectored COVID-19 vaccine
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zhejiang Provincial Center for Disease Control and Prevention
Pneumococcal Infections
Study Comparing a 13-valent Pneumococcal Conjugate Vaccine With 23-valent Pneumococcal Polysaccharide Vaccine in Adults
This study will assess the safety, tolerability and immune response of 13-valent pneumococcal conjugate vaccine (13vPnC) compared with 23-valent Pneumococcal Polysaccharide Vaccine (23vPS).
- Trial name
- NCT00427895
- Testing
- 13-valent pneumococcal conjugate vaccine (13vPnC), 23-valent Pneumococcal Polysaccharide Vaccine (23vPS)
- Where
- 26 sites in United States
- Volunteers
- 2,141 people, healthy volunteers welcome
- Sponsor
- Pfizer
Old Age
Multi-nutrient Supplement to Improve Physical Performance in Older Adults
Geriatric Day Hospitals (GDH) of the McGill University Health Centre and l'Institut de Gériatrie de Montreal offer comprehensive rehabilitation programs including physiotherapy and medical care, but no dietetic counselling for…
- Trial name
- NCT04454359
- Testing
- Multi-nutrient supplement
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- McGill University
COVID-19, SARS-CoV-2
Safety and Immunogenicity Study of a Booster Dose of the Investigational CV0501 mRNA COVID-19 Vaccine in Adults at Least 18 Years Old
Prevention of COVID-19 caused by SARS-CoV-2.
- Trial name
- NCT05477186
- Testing
- CV0501 (3 μg), CV0501 (6 μg), CV0501 (12 μg)
- Where
- 17 sites in United States, Australia and 1 more
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy
An Exploratory Study to Evaluate the Prophylactic Efficacy of a Single Immunization of Ad26.RSV.preF Against Respiratory Syncytial Virus Infection in a Virus Challenge Model in Healthy 18 to 50 Year-old Adults
The purpose of this study is to assess a trend for the prophylactic efficacy of a single dose of 1*10^11 virus particles (vp) of adenovirus serotype 26 respiratory syncytial virus pre-fusion F protein (Ad26.RSV.preF) administered…
- Trial name
- NCT03334695
- Testing
- Ad26.RSV.preF
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Janssen Vaccines & Prevention B.V.
Accidental Fall, Neurologic Disorder
A Community-Based Falls Prevention Program for Adults At-Risk for Falls
The goal of this interventional study is to implement a Falls Prevention Program to impact the risk and injuries related to falls.
- Conditions
- Accidental Fall, Neurologic Disorder, Old Age; Debility, Healthy Aging
- Trial name
- NCT05771818
- Testing
- Falls Prevention Program
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of St. Augustine for Health Sciences
Cognition Disorders in Old Age
A Feasibility Trial and Protocol for Remote Cognitive Training Developed for Use in a Cognitively Healthy Adult Population During the COVID-19 Pandemic
The COVID-19 pandemic has created a shift in the use of at-home spaces for work, play and research. In the current study, the feasibility of implementing an at-home cognitive training tool called NeuroTrackerX, an anaglyph…
- Trial name
- NCT05278273
- Testing
- NeurotrackerX
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Victoria