Clinical trials: Older Men
Frail Elderly, Aging
Targeting Aging With a Ketone Ester for Function in Frailty
This study aims to find out if a food supplement that contains a naturally occurring substance, ketones, can help to improve strength and general wellness in adults at, or over the age of 65 years who are experiencing a slight…
- Conditions
- Frail Elderly, Aging, Immune Function, Muscle Function
- Trial name
- TAKEOFF (NCT06645847)
- Testing
- Ketone ester
- Where
- 3 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Buck Institute for Research on Aging
Myopathy
Maintenance of Muscle Mass in Older People: the Negative Impact of Statin Therapy
A major contributor to frailty and immobility in the elderly is the age related loss of muscle mass (sarcopenia). Cardiovascular disease (CVD) is the leading cause of mortality in the elderly, with high blood cholesterol and…
- Trial name
- NCT01047163
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Sarcopenia, Osteopenia
Exercise Effects on Sarco-Osteopenia in Older Men
The study determined the effects of predominately resistance type exercise in combination with protein supplements on parameters of sarcopenia and osteopenia (sarco-osteopenia) in older, community dwelling men with sarcopenia and…
- Trial name
- NCT03453463
- Testing
- exercise
- Where
- Germany
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Ageing Well
A Pilot Study on Skeletal Muscle Proteome Dynamics in Younger and Older Men Undertaking Normal Activity or Resistance Exercise Training.
The goal of this basic research study is to investigate effect of resistance exercise on the quality of muscle proteins in younger and older men.
- Trial name
- LHMA Pilot (NCT07473297)
- Testing
- Resistance Exercise
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Insulin Resistance, Age Problems
Investigating the Effects of Beta-Hydroxy-Beta-Methylbutyrate on Glucose Handling in Older and Younger Men.
This study intends to examine the effect of a commercially available nutritional supplement, Beta-hydroxy-beta-methylbutyrate(HMB) on whole-body responses to a sugar load.
- Trial name
- NCT03018496
- Testing
- Beta-Hydroxy-Beta-Methylbutyrate
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Aging
Fatigability of Lower Limb Muscle in Older Adults: Protective Effects of Strength Training Exercise in Old Men and Women
The proposed studies will assess 1) the mechanisms for the age-related increase in fatigability during dynamic exercise (Aims 1 and 2) and 2) the effectiveness of high-velocity resistance training coupled with blood flow…
- Trial name
- NCT03888040
- Testing
- Exercise
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Marquette University
Sarcopenia
Resistance Exercise for the Prevention of Age-related Sarcopenia
The purpose of this study is to determine the benefits of negative work progressive resistance exercise (PRE) for the conservative management of sarcopenia in older male Veterans at the DC VAMC.
- Trial name
- REPAiRS (NCT01355861)
- Testing
- Negative work exercise
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Oral Health of Older Men
Talking Pen Audio-Interactive Program for Oral Frailty Delay in Community-Dwelling Elderly
This study aims to develop and evaluate the effectiveness of a talking pen audio-interactive technology integrated with an oral frailty delay care program for community-dwelling older adults in rural agricultural regions of…
- Trial name
- NCT07191600
- Testing
- Talking Pen Audio-Interactive Oral Frailty Care Program
- Where
- Taiwan
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Chang Gung University of Science and Technology
HIV, PrEP
Self-Consent for PrEP Perspectives
This study involves a one-time, web-based quantitative structured self-complete ("web-based") survey for all subjects and a qualitative semi-structured ("qualitative") interview for a selected sub-sample of subjects to evaluate…
- Trial name
- NCT02801760
- Where
- 11 sites in United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Bone Strength, Neuromuscular Function
The Influence of High Impact Exercise on Musculoskeletal Health in Older Men
Osteoporotic fractures are an extremely common and serious public health issue which contribute substantially to pain, impaired mobility and morbidity in the elderly.
- Trial name
- Hiphop (NCT02007460)
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Exercise Training
Plyometric Exercise to Improve Rapid Force Production in Older Men
Rapid force production declines as a consequence of ageing. Given the functional relevance of rapid force production, exercise interventions in older adults should aim at improving the capacity to produce force rapidly.
- Trial name
- NCT03645772
- Testing
- Exercise intervention
- Where
- Belgium
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Aging
Fiber and Calcium Absorption in Older Men
Osteoporotic fractures are a major but underrecognized problem in men. There is growing evidence that low dietary fiber intake is a modifiable risk factor for age-related bone loss in men.
- Trial name
- NCT06519877
- Testing
- Soluble corn fiber
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Aging
Project SIRT6 Activator
The global ageing population is increasingly affected by age-related diseases, which are challenging healthcare systems. Current treatments often extend lifespan without improving healthspan.
- Trial name
- NCT07500649
- Testing
- Fucoidan
- Where
- 2 sites in Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Chronic Disease of Cardiovascular System, Multiple Chronic Conditions
MOCHA Moving Forward: a CBPR Investigation of Chronic Disease Prevention in Older, Low-income African-American Men
The overall goal of the research is to discover how to reduce chronic disease health disparities among older (ages 35-70) low-income African-American men more effectively.
- Conditions
- Chronic Disease of Cardiovascular System, Multiple Chronic Conditions, Chronic Disease
- Trial name
- NCT03745703
- Testing
- MOCHA
- Where
- 2 sites in United States
- Volunteers
- 261 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Older Adults, Reduced Physical Activity
Step-reduction in Older Men and Women
This study investigates the effects of two weeks of reduced daily ambulation and a subsequent return to normal physical activity on metabolic health of older adults.
- Trial name
- CDA-SR (NCT03039556)
- Testing
- Normal Daily Steps, Step-Reduction, Return to Normal Daily Steps
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- McMaster University
Physical Inactivity, Mobility Limitation
The Men on the Move Study
The Men on the Move Study is a randomized, controlled, feasibility study designed to address the health problem of physical inactivity in older men.
- Conditions
- Physical Inactivity, Mobility Limitation, Older Men
- Trial name
- NCT02527655
- Testing
- Choice-Based Physical Activity and Active Transportation
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Simon Fraser University
Healthy
Isokinetic Testing Protocol in Elderly and Young Men
An age-related decrease in muscular strength may have a detrimental effect on muscle fatigue and recovery. To date, only one study has determined the effect of varied rest intervals (RI) between exercise sets in active younger…
- Trial name
- NCT00673998
- Testing
- Isokinetic Dynamometer (Biodex system III)
- Where
- Brazil
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Brasilia
Aging
The Effect of Velocity Training in Functionally Limited Elderly
We are exploring a unique weight-training program for men and women 65 years or older that emphasizes high speed training. We believe that the speed at which muscles move may be more important to the performance of functional…
- Trial name
- NCT01211496
- Testing
- High-speed power training, Slow-speed strength training
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Cognitive Function, Mood
A Study by ChromaDex to Assess the Effects of TRU NIAGEN on Cognitive Function, Mood and Sleep in Older Adults
The sponsor of this study is ChromaDex, Inc. This is a double-blind, randomized, crossover study to investigate the effects of 300 mg/d and 1000 mg/d TRU NIAGEN (nicotinamide riboside) compared to a placebo control on cognitive…
- Conditions
- Cognitive Function, Mood, Sleep
- Trial name
- NCT03562468
- Testing
- 300 mg/day of TRU NIAGEN (nicotinamide riboside), 1000 mg/day of TRU NIAGEN (nicotinamide riboside)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- ChromaDex, Inc.
Tolerance, Safety Issues
Buck Institute Ketone Ester RCT
This study is to investigate the tolerability and safety of a ketone promoting ingredient, called a ketone ester (KE), in healthy older adults.
- Conditions
- Tolerance, Safety Issues, Aging
- Trial name
- BIKE (NCT05585762)
- Testing
- Ketone ester
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Buck Institute for Research on Aging