Clinical trials: Open Bite
Anterior Open Bite Malocclusion
Efficiency of Microosteoperforation for Accelerating Posterior Segment Intrusion in Skeletal Open Bite Cases
This clinical trial aimed to assess the efficiency of micro-osteoperforation for accelerating posterior intrusion in open bite cases.
- Trial name
- NCT07761065
- Testing
- Micro-osteoperforation, Conventional posterior segment intrusion
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Denture Retention
A Study to Assess the Effectiveness of a Marketed Denture Adhesive in Real-World Setting
The purpose of this decentralised study in a real-world setting is to assess the effectiveness of a marketed denture adhesive (Poligrip Power Max Hold + Seal) in preventing food entrapment under dentures (self-assessed).
- Trial name
- NCT07273149
- Testing
- Poligrip Power Max Hold + Seal
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- HALEON
Postoperative Pain Management
A Comparative Study Between Different Volumes During Erector Spinae Block for Pain Control
Since its first description by Forero et al. there have been many articles and case reports including an increasingly number of indications for the ESP block: chronic and acute pain treatment, rib fractures management in the…
- Trial name
- NCT04371341
- Testing
- erector spinae block by 0.25% bupivacaine
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anterior Open Bite
Palatal Crib Versus Bonded Spurs in Early Treatment of Anterior Open Bite Caused by Non-nutritive Sucking Habits: RCT
The study evaluates the effects of palatal crib versus bonded spurs in the early treatment of anterior open bite caused by non-nutritive sucking habits.
- Trial name
- NCT05313399
- Testing
- Palatal Crib, bonded spur
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Reem Hatem Shams
Healthy
Primary Irritation Patch Test (PIPT) Study Conducted at NovoBliss Research for Shared Panel
This is a single-center, evaluator-blinded study in healthy adult human subjects. Single 24-hour application of sponsor(s) provided test products along with positive and negative controls will be kept in contact with the skin of…
- Trial name
- NCT05642702
- Testing
- Peptide complexed HA Age Defying Gel with Vitamin C & Niacinamide, Peptide complexed HA Age Defying Gel with Natural Extracts, Peptide complexed HA Age Defying Gel with Vitamin C & Natural Extracts
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Maxillary Molar Intrusion
Evaluation of Maxillary Posterior Teeth Intrusion by Skeletally Anchored Mousetrap Appliance in Adult Patient With Anterior Open Bite.
Aim of the study: This clinical study aims to evaluate the dental, skeletal, and soft tissue effects of the Mousetrap appliance on the intrusion of maxillary posterior teeth in adult patients with anterior open bite.
- Trial name
- NCT06757686
- Testing
- Mousetrap appliance
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Normal Skin
To Check Dermatological Safety of Test Products by 24 Hours Patch Test on Adult Healthy Human Subjects.
This is single-center, evaluator blinded study in healthy human subjects. single 24-hour application of sponsors provided test product along with positive and negative control will be kept in contact with the skin if subject…
- Trial name
- NCT06631898
- Testing
- SaaTwae Bio-Natural Moisturizing Cream
- Where
- India
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Crossbite, Openbite
Implications of Pacifier Use in Israeli Children
The purpose of this study is to examine pacifier sucking habits among children, and to assess implications of the oral habit - for example malocclusions and drooling.
- Conditions
- Crossbite, Openbite, Drooling
- Trial name
- NCT01249885
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Hemorrhage, Healthy Volunteers
Healthy Adults Aged 18-55, Three Ukrainian Windlass Tourniquets (SICH, DNIPRO GEN 2, PULS) Compared With CAT Gen 7, and Complete Limb Arterial Occlusion Confirmed by Doppler.
The goal of this clinical trial is to learn if three Ukrainian-made windlass tourniquets (SICH, DNIPRO GEN 2 and PULS) stop arterial blood flow in the arm or leg as well as the Combat Application Tourniquet (CAT Gen 7) does.
- Conditions
- Hemorrhage, Healthy Volunteers, Arterial Occlusion
- Trial name
- TORQUE (NCT07900360)
- Testing
- Windlass-type hemostatic tourniquet SICH, Windlass-type hemostatic tourniquet Dnipro, Windlass-type hemostatic tourniquet PULS, Windlass-type hemostatic tourniquet CAT Gen 7 (reference)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Foundation for Expert Deployment for Governance and Economic Growth (EDGE)
Orthodontics
The Effect of Different Force Magnitudes on Maxillary Posterior Segment Intrusion
A Randomized clinical trial comparing two different force magnitudes in maxillary posterior segment intrusion in adult patients with skeletal open bite malocclusion
- Trial name
- NCT02901678
- Testing
- Intrusion by 400 g
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Study Vasodilatory Effects of C21
Effect of C21 on Forearm Blood Flow
The purpose of this study is to assess the effect of C21 on forearm blood flow by use of strain-gauge venous occlusion plethysmography.
- Trial name
- NCT05277922
- Testing
- C21, Sodium Nitroprusside
- Where
- Sweden
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Vicore Pharma AB
Sterilization, Female, Fallopian Tube Occlusion
Development of an Intrauterine Pressure Threshold to Confirm Tubal Occlusion
The overarching goal of this study is to find an alternative method to hysterosalpingogram (HSG) to confirm bilateral tubal occlusion after permanent contraception.
- Trial name
- NCT04071392
- Testing
- Hysterosalpingogram (HSG)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Retinitis Pigmentosa, Macula Off
Transcorneal Electrical Stimulation Therapy for Retinal Disease
Transcorneal stimulation may enable neurons to survive degeneration processes via enhanced secretion of neurotrophic substances and direct stimulation of neurons.
- Conditions
- Retinitis Pigmentosa, Macula Off, Primary Open Angle Glaucoma, Hereditary Macular Degeneration
- Trial name
- NCT00804102
- Testing
- Transcorneal Electrical Stimulation, DTL-electrode attached without energy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Okuvision GmbH
Healthy Participants
To Check Dermatological Safety of Test Products by 24 Hours Patch Testing
To Check Dermatological Safety of Test Products by 24 Hours Patch Testing
- Trial name
- NCT07060976
- Testing
- 18 Transdermal patches along with positive and negative controls 1)Capsaicin0.025% Topical Patch, 2)Diclofenac Diethylamine 100mg Transdermal Patch, 3)Diclofenac Diethylamine 200mg Transdermal Patch,
- Where
- India
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Novamed Laboratories Pvt. Ltd.
Premenstrual Syndrome
A Study to Evaluate the Effect of Funk It Cycle Bites on PMS
This is a virtual, open-label, single-group study that will last 4 menstrual cycles. All participants will complete a questionnaire at the end of their first period after enrolling (baseline/non-intervention cycle 1), then…
- Trial name
- NCT05900024
- Testing
- Funk It Cycle Bites
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Funk It Wellness
Snake Bites
Safety and Effectiveness of PANAF-Premium TM Snake Venom Antiserum As Standard Treatment for Snakebites
Snakebite envenomation (SBE) is a major public health problem in many developing countries. Standard snake antivenom (SA) remains the primary treatment and has been shown to reduce mortality in observational studies conducted in…
- Trial name
- PMS (NCT06615960)
- Where
- Cameroon
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Premium Serums & Vaccines Pvt.Ltd.
Sleep Related Breathing Disorder, Snoring
IOA Preventing Occlusal Changes With MAD Use
This study is evaluating two standard-of-care strategies used to prevent bite changes (occlusal changes) in patients treated with a Mandibular Advancement Device (MAD) for sleep-related breathing disorders such as obstructive…
- Conditions
- Sleep Related Breathing Disorder, Snoring, Obstructive Sleep Apnea (OSA), Open Bite
- Trial name
- NCT07103941
- Testing
- AM Aligner, Exercise
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Isabel Moreno Hay
Denture Retention
A Study to Investigate a Method to Measure Food Occlusion by Denture Adhesives in Denture Wearers
The purpose of this study is to evaluate a methodology to determine the ability of a denture adhesive to restrict food ingress underneath dentures during eating.
- Trial name
- NCT03345108
- Testing
- Denture Adhesive Cream (Conventional Application), Denture Adhesive (Continuous Strip Application), No Adhesive
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Plasmodium Falciparum Infection
Trial to Evaluate the Safety, Immunogenicity and Protective Efficacy of Three or Five Administrations of GAP3KO Sporozoites
This Phase 1 trial will include 16 subjects who will receive the Genetically-attenuated p52-/p36-/sap1- Plasmodium falciparum Parasites (GAP3KO) vaccine administered by the bite of approximately 200 infected Anopheles stephensi…
- Trial name
- NCT03168854
- Testing
- Genetically-attenuated p52-/p36-/sap1- Plasmodium falciparum parasite (GAP3KO) strain, Malaria challenge
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Open Bite
Myofunctional Therapy in Open Bite - RCT
The goal of this clinical trial is to learn if myofunctional therapy in 6-10-year-old children with infant type of swallowing and open bite is effective.
- Trial name
- Myofunctional (NCT06574490)
- Testing
- Myofunctional therapy (+), Myofunctional therapy (-)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Piotr Fudalej