Clinical trials: Open Surgical Wounds
Mandibular Fractures
Precision of Patient Specific 3D Printed Occlusal Stent, Surgical Guide, and Patient Specific Titanium Plates in Management of Mandibular Fracture (Case Series)
This study evaluates the accuracy of preoperative fully computerized occlusal stents, surgical guide, and patient-specific titanium plates in guided mandibular fracture reduction and fixation.
- Trial name
- NCT07499726
- Testing
- Patient-Specific 3D Printed Occlusal Stent, Surgical Guide, and Titanium Plates
- Where
- Egypt
- Volunteers
- 6 people
- Sponsor
- Cairo University
Wound and Injuries, Surgical Wound Dehiscence
The Clinical Efficacy of RENASYS TOUCH NPWT System in the Management of Acute, Sub-acute and Chronic Wounds
The study is looking at the clinical efficacy, functionality and device performance of a new Negative Pressure Wound Therapy (NPWT) system in the management of a variety of wound types, in a real-life clinical setting.
- Trial name
- NPWT (NCT02565043)
- Testing
- RENASYS TOUCH Negative Pressure Wound Therapy System
- Where
- 2 sites in South Africa
- Volunteers
- 80 people
- Sponsor
- Smith & Nephew, Inc.
Surgery, Pneumonia
Multicenter Infection Surveillance Study Following Open Heart Surgery
The main goals of the study are as follows: (1) to determine the correlation between pain management using continuous infusion of local anesthetics and the incidence of pneumonia and surgical infection in cardiac surgery…
- Conditions
- Surgery, Pneumonia, Surgical Site Infection
- Trial name
- NCT00673712
- Testing
- Continuous Sternal Block, Opioid based analgesia
- Where
- 8 sites in United States
- Volunteers
- 647 people
- Sponsor
- Halyard Health
Patients Undergoing Clean Surgery
OPSITE Post-Op Visible Wound Dressings in Treatment of Surgical Incisions
OPSITE Post-Op Visible is a tri-layer dressing made up of a low adherent wound contact layer, lattice shaped absorbent pad and a top film that is waterproof and a bacterial barrier and is coated with a water-based adhesive.
- Trial name
- OPOV (NCT01577225)
- Testing
- OPSITE POST-OP VISIBLE, Tape and Gauze
- Where
- 6 sites in China
- Volunteers
- 100 people
- Sponsor
- Smith & Nephew Medical (Shanghai) Ltd
Surgical Site Infection
Intradermal Suture Versus Stapling for Groin Skin Closure in Vascular Surgery (VASC-INF Trial)
Surgical site infection (SSI) is one of the most frequent and fearsome complications in vascular surgery due to its high morbidity and mortality.
- Trial name
- NCT05434182
- Testing
- Intradermal Suture, Metallic Staples
- Where
- Spain
- Volunteers
- 225 people
- Sponsor
- Hospital Universitari de Bellvitge
Traumatic Lacerations or Surgical Incisions
Safety and Efficacy Study of BondEase to Treat Traumatic Lacerations and Surgical Incisions
To demonstrate that BondEase™ and conventional wound closure devices (CWCD) are the same in terms of cosmesis (appearance) of the repaired wound when these devices are used for closure of surgical and traumatic wounds .
- Trial name
- NCT01716013
- Testing
- BondEase, CWCD
- Where
- 6 sites in United States
- Volunteers
- 162 people
- Sponsor
- OptMed, Inc.
Surgical Site Infection, Unplanned Fracture-Related Reoperation
Pre-operative Aqueous Antiseptic Skin Solutions in Open Fractures
The prevention of infection is the single most important goal influencing peri-operative care of patients with open fractures. Standard practice in the management of open fractures includes sterile technique and pre-operative…
- Conditions
- Surgical Site Infection, Unplanned Fracture-Related Reoperation, Open Appendicular Fracture
- Trial name
- Aqueous-PREP (NCT03385304)
- Testing
- 10% povidone-iodine (1% free iodine) in purified water, 4% chlorhexidine gluconate (CHG) in purified water
- Where
- 15 sites in United States, Canada and 1 more
- Volunteers
- 1,638 people
- Sponsor
- University of Maryland, Baltimore
Pilon Fractures, Fractures
Surgery of the Pilon Fractures
The assessment consists in comparing the osteosynthesis plate with minimally invasive technique versus open reduction and internal fixation.
- Conditions
- Pilon Fractures, Fractures, Bone, Leg Injuries
- Trial name
- MICOPIL (NCT03367169)
- Testing
- minimally invasive method, open reduction method
- Where
- France
- Volunteers
- 54 people
- Sponsor
- University Hospital, Clermont-Ferrand
Renal Failure
The Efficacy of "MediHoney" to Facilitate Catheter Exit-Site Surgical Wound Healing
To evaluate the efficacy of honey as a post surgical exit site care process to promote healing and prevent infectious bacterial colonization of newly created exit sites.
- Trial name
- NCT01230489
- Testing
- MediHoney
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Missouri-Columbia
Intra-articular Fracture of the Mandibular Condyle
Treatment of Intra-articular Fractures of the Mandibular Condyle
Intra-articular fractures of the mandibular condyle ((IAFC) are usually treated by means of physical therapy with or without transient maxillo-mandibular fixation (conservative or closed treatment).
- Trial name
- FIAC (NCT04776473)
- Testing
- Open treatment, Closed treatment
- Where
- 7 sites in France
- Volunteers
- 110 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pilonidal Sinus, Wound Healing
ENVELOP: Wound Care Following Pilonidal Sinus Surgery
This is a single-blinded, multicentre, prospective randomised controlled trial (RCT) comparing post-operative and patient-reported outcomes for patients undergoing application of negative-pressure wound therapy (NPWT) after sinus…
- Trial name
- ENVELOP (NCT06647290)
- Testing
- Negative Pressure Wound Therapy, Standard wound care
- Where
- 10 sites in Ireland
- Volunteers
- 200 people
- Sponsor
- Royal College of Surgeons, Ireland
Biliary Tract Diseases, Gallbladder Diseases
Small-incision Open Cholecystectomy or Laparoscopic Cholecystectomy for Gallbladder Disease
The trial compares minilaparotomy (small-incision) cholecystectomy with (key-hole) laparoscopic cholecystectomy by randomly allocating patients with gallbladder disease to two groups of surgeons, each group being trained for one…
- Conditions
- Biliary Tract Diseases, Gallbladder Diseases, Cholecystitis, Cholecystolithiasis
- Trial name
- NCT00370344
- Testing
- Laparoscopic cholecystectomy, Small-incision open cholecystectomy
- Where
- 2 sites in Sweden
- Volunteers
- 355 people
- Sponsor
- Umeå University
Tennis Elbow
Platelet Rich Plasma vs Open Surgery in the Treatment of Tennis Elbow
Chronic Lateral Epicondylar Tendinopathy is a debilitating condition that is associated with repetitive use of the forearm extensor muscles.
- Trial name
- NCT02755727
- Testing
- Platelet Rich Plasma Injection, Open Surgical Release
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Inguinal Hernia, Hydroceles
Prevention of Surgical Site Infection in Open Paediatric Groin Surgeries Using Intravenous Prophylactic Antibiotics and Antimicrobial-coated Sutures
The goal of this clinical trial is to learn if the use of prophylactic antibiotics and antimicrobial-coated sutures can prevent surgical site infection in children undergoing open groin surgeries.
- Conditions
- Inguinal Hernia, Hydroceles, Surgical Site Infection
- Trial name
- NCT07346742
- Testing
- Antimicrobial-coated sutures, Intravenous Cefuroxime
- Where
- Nigeria
- Volunteers
- 174 people
- Sponsor
- Olawumi Olajide
Femur Fracture
Vastus Intermedius Dry Needling for Knee Stiffness Resulted From Surgically Managed Femoral Fractures With Open Reduction & Internal Fixation.
Orthopedic traumatic injuries are considered a major health epidemic, challenged by high morbidity, mortality, and socioeconomic burden.
- Trial name
- NCT06307587
- Testing
- dry needling
- Volunteers
- 44 people
- Sponsor
- Al-Razi Hospital
Femoral Fractures
Study Of Tranexamic Acid For The Reduction Of Blood Loss In Patients Undergoing Surgery For Long Bone Fracture
Tranexamic acid has been shown to reduce postoperative blood losses and transfusion requirements in a number of types of surgery.
- Trial name
- NCT00824564
- Testing
- Tranexamic Acid plus standard of care, Standard of care
- Where
- India
- Volunteers
- 82 people
- Sponsor
- Pfizer
Hernia, Obesity
Evaluation of Surgisis Gold Graft for Incision Reinforcement After Open Bariatric Surgery
The primary objective is to compare the effectiveness of the Surgisis Gold Graft to suture closure alone in preventing an incisional hernia after open bariatric surgery.
- Trial name
- NCT00274625
- Testing
- Surgisis Gold Graft, Control
- Where
- 2 sites in United States
- Volunteers
- 402 people
- Sponsor
- Cook Group Incorporated
Surgical Wound Infection
Clinical Assessment of Next Science Solution on Gustilo and Anderson Type II and IIIA or IIIB Tibial Fractures
This is a prospective, randomized, controlled, double-blinded clinical feasibility study of subjects that are being treated for Gustilo and Anderson Type II or IIIA or IIIB Tibial Fractures
- Trial name
- NCT04906642
- Testing
- Next Science, Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Next Science TM
Postoperative Pain, Wrist Fracture
Comparing Efficacity of Analgesia Between Ultrasound-guided Nerve Block and Local Infiltration After Wrist Fracture Surgery
Distal radial fracture reparations by volar plating are often managed under regional anaesthesia, but are associated with severe pain when the block ends.
- Trial name
- BNINF (NCT02693288)
- Testing
- Local infiltration anesthesia
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Shoulder Impingement Syndrome, Adhesive Capsulitis
Sayed Issa's Hybrid Shoulder Arthroscopic-Open Surgical Management (HSSM)
Sayed Issa's Hybrid Shoulder Arthroscopic-Open Surgical Management (HSSM) is a limited lateral approach to the shoulder arthroscopically guided.
- Conditions
- Shoulder Impingement Syndrome, Adhesive Capsulitis, Rotator Cuff Tear, Hill-Sachs Lesion
- Trial name
- HLSSM (NCT05897866)
- Testing
- Sayed Issa's Hybrid Shoulder Arthroscopic-Open Surgical Management
- Where
- Syria
- Volunteers
- 44 people
- Sponsor
- Issa, Abdulhamid Sayed, M.D.