Clinical trials: Orofacial Pain
Temporomandibular Disorder, Myofascial Pain
CBD (Cannabidiol) Intraoral Application and TMD (Temporomandibular Disorders)
The aim of the project is to assess the effectiveness of reducing the masseter muscles tension and hyperactivity in patients with a painful form of TMD by using polymers containing CBD compared to placebo polymers.
- Conditions
- Temporomandibular Disorder, Myofascial Pain, Orofacial Pain, CBD
- Trial name
- NCT05562635
- Testing
- 5% polymer gel with CBD application, 10% polymer gel with CBD application
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Oral-facial Pain
Impact of Palmitoylethanolamide (PEA) in the Management of Oro-facial Pain
Pain is the most common symptom faced by dentists, whether acute (pulpitis, acute periodontitis, post-surgical, etc.) or chronic (chronic periodontitis, muscle pain, TMJ disorders, BMS, OLP, etc.).
- Trial name
- NCT05877170
- Testing
- Palmitoyletinolamide
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Catania
Toothache, Temporomandibular Joint Disorders
Multimodal Assessment of Sensory Processing and Brain Features in Patients With Chronic Orofacial Pain
This proposal will investigate pain modulatory mechanisms and brain functional and structural characteristics using multiple MRI modalities in persistent dentoalveolar pain disorder (PDAP) patients with and without…
- Trial name
- NCT02630771
- Testing
- Pressure pain threshold
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Temporomandibular Disorder, Temporomandibular Joint Disorders
Influence of Stabilization Splint Thickness on The Temporomandibular Disorders
The aim of the study is assessing the effect of the stabilization splint (SS) thickness on the temporomandibular disorder's and their symptoms; such as muscle or temporomandibular joint (TMJ) pain, TMJ sounds, and limitation of…
- Conditions
- Temporomandibular Disorder, Temporomandibular Joint Disorders, Orofacial Pain
- Trial name
- NCT04524806
- Testing
- stabilization splint
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Motor Imagery Training, Physical Exercise
Acute Effects of Motor Imagery and Physical Exercise on Tongue Strength and Pain Threshold in Healthy Adults
Motor imagery is the feeling and thinking that the movement is done by imagination without physically occurring. In addition to its use in various fields, its use in the field of physiotherapy is also increasing.
- Conditions
- Motor Imagery Training, Physical Exercise, Orofacial Exercise
- Trial name
- NCT04822896
- Testing
- Physical Exercise, Kinesthetic Motor Imagery Exercises, Visual Motor Imagery Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Temporomandibular Dysfunction (TMD), Orofacial Pain
Electrostimulation Therapies With Implementation of Multifractal Electromyographic Analysis
The objective is to compare the neuromuscular electrical activity and muscle fatigue of the masseter muscles in three groups of patients with different treatments for TMD (GA = Transcutaneous electrostimulation and splint, GB =…
- Trial name
- NCT04704778
- Testing
- Transcutaneus electrostimulation therapies, Percutaneus electrostimulation therapies, Oclusal splint
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Mexico
Orofacial Pain, Sleep Problems
Orofacial Pain in Woodwind and Cello Musicians in German Orchestras
Professional musicians in German professional orchestras represent a population group that has received little attention so far, despite being exposed to a variety of work-related factors that may pose potential health risks to…
- Trial name
- NCT06618898
- Testing
- online questionnaire
- Where
- Germany
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen
Bruxism, Temporomandibular Joint Disorders
Aspects Associated With Obstructive Sleep Apnea, Bruxism and Orofacial Pain
This study evaluated the influence of the sleep bruxism (SB), awake bruxism (AB) and obstructive sleep apnea syndrome (OSAS) on the signs and symptoms of temporomandibular disorders (TMD).
- Conditions
- Bruxism, Temporomandibular Joint Disorders, Obstructive Sleep Apnea Syndrome
- Trial name
- NCT03766464
- Testing
- Evaluation of TMD and pain sensitivity, Evaluation of SB, Evaluation of AB
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Chronic Masticatory Myofascial Pain
Masticatory Muscle Activity Using a 24-Hour Wearable Device
Patients with chronic masticatory myofascial pain (MFP) often report that stress and parafunctional oral habits aggravate their pain, consistent with the widespread belief that stress and parafunctional habits lead to…
- Trial name
- NCT07861906
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Midwestern University
Temporomandibular Disorders, Rheumatoid Arthritis
Biomarkers Associated With Temporomandibular Disorders in Patients With Rheumatoid Arthritis
The goal of this observational study is to determinate temeporomandibular disorders (TMDs) and levels of biomarkers in 30 rheumatoid arthritis patients and 30 healthy controls.
- Trial name
- NCT06488937
- Where
- Croatia
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Tension-Type Headache, Orofacial Pain
Laser Therapy on Tension-type Cephalea and Orofacial Pain in Post-covid-19 Patients
Considering the auxiliary potential effect of photobiomodulation in controlling persistent CTT and TMD-related pain in patients who have been diagnosed with COVID-19, and are recovered from the viral infection, we intend to…
- Conditions
- Tension-Type Headache, Orofacial Pain, COVID-19
- Trial name
- NCT05430776
- Testing
- Photobimodulation
- Where
- 2 sites in Brazil
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Airway Management, Endotracheal Intubation
The Effect of Different Methods of Airway Management on the Stomatognathic System: an Observational Prospective Study.
The manipulations required during airway management and the different methods of establishing an airway (endotracheal intubation, supraglottic airway device etc) during anesthesia, as well as certain drugs used during anesthesia…
- Conditions
- Airway Management, Endotracheal Intubation, Supraglottic Airway Device, Regional Anesthesia
- Trial name
- NCT05783128
- Testing
- Airway management techniques (exposure)
- Where
- Greece
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Aretaieio Hospital
Temporomandibular Disorder, Headache Disorders
Validation of the TMD Pain Screener in a Specialized Headache Center
The purpose of the study is to investigate whether a questionnaire can be used to detect whether patients referred to the Danish Headache Center have a painful temporomandibular disorder (TMD).
- Trial name
- NCT04193111
- Testing
- TMD pain screener
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Mastication Disorder, Fatigue
Validation and Evaluation of the Mastication Function in Adults: The Functional Six-minute Mastication Test (F-6MMT).
Temporomandibular Disorders (TMD) encompass various conditions that affect the temporomandibular joint and associated tissues, often causing or being associated with other symptoms such as jaw pain, myofascial pain, neck pain…
- Conditions
- Mastication Disorder, Fatigue, Temporomandibular Disorder, Orofacial Pain
- Trial name
- F-6MMT (NCT06298786)
- Testing
- Functional 6-minute mastication test
- Where
- 3 sites in Spain
- Volunteers
- 514 people, healthy volunteers welcome
- Sponsor
- Fundació Universitària del Bages
Temporomandibular Joint Disorders
Acute Effects of Alcohol Use on Chronic Orofacial Pain
Self-medication of pain with alcohol is a common, yet risky, behavior among individuals with chronic orofacial pain. Chronic pain status may affect the degree to which alcohol use relieves pain, but the independent contributions…
- Trial name
- NCT04019093
- Testing
- Ethanol
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Florida
Temporomandibular Joint, Conservative Treatment Therapy
The Use of PET/CT to Evaluate Synovitis in the Temporomandibular Joint (TMJ)
Temporomandibular joint disorders (TMD) are a common musculoskeletal problem with an estimated 40-75 percent of the population reporting at least one sign.
- Trial name
- NCT01471418
- Testing
- PET/CT with 18-FDG
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Temporomandibular Disorders (TMDs)
Diagnostic Study Accuracy of Jaw Motion Analyzer(JMA) Versus Research Diagnostic Criteria(RDC/TMD) and Magnetic Resonance Imaging(MRI) for Temporomandibular Disorders Among Patients With Chronic Orofacial Pain.
The goal of this diagnostic accuracy study is to determine the diagnostic accuracy of jaw motion analyzer(JMA) in terms of sensitivity and specificity with target cut of points used by valid reference standards which will be the…
- Trial name
- NCT07486609
- Testing
- The Jaw Motion Analyzer (JMA, Zebris, Germany) as the index test, Research Diagnostic Criteria for Temporomandibular Disoders, Magnetic Resonance Imaging
- Where
- Egypt
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Pain
Emotional Intelligence and Chronic Orofacial Pain
Chronic pain, lasting more than three months, is a widespread health issue that negatively impacts daily life, leading to significant emotional distress and functional impairment.
- Trial name
- IEDOF (NCT07280338)
- Testing
- Questionnaire and Physical Exam
- Where
- France
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Myofascial Pain Syndromes, Facial Pain
Comparative Analysis of Dry Needling Techniques for Orofacial Myofascial Pain
This study aims to compare the clinical effectiveness and individual comfort of three distinct dry needling techniques (dynamic, static, and hybrid) for managing orofacial myofascial pain.
- Conditions
- Myofascial Pain Syndromes, Facial Pain, Trigger Points
- Trial name
- NCT07706153
- Testing
- Dry needling
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Flávio Magno Gonçalves
Education, Medicine
Musicians' Health Education in D-A-CH
Professional musicians are often exposed to significant physical and psychological strain. Long hours of playing, high muscle tension in the head and neck area, and performance-related stress can lead to problems such as…
- Conditions
- Education, Medicine, Dentistry, Orofacial Pain
- Trial name
- MUSED-DACH (NCT07443930)
- Where
- Germany
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen