Clinical trials: Orthodontic Appliance
Orthodontic Appliance Complication
Evaluation Of Anchorage Control Using Arch Wire Stopper Versus Mini-Screws
The study aims to compare the anchorage control using arch wire stopper versus mini-screws in post-pubertal patients with maxillary dentoalveolar protrusion
- Trial name
- NCT06416904
- Testing
- archwire stopper mesial to the maxillary first molar group, inter-radicular mini-screw
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Orthodontic Appliances
Benefits of an Orthodontic Device Removable Functional Appliance in the Management of Malocclusions/Orofacial Dysfunctions
The removable functional appliance's goal is to restore functional balance (breathing, swallowing, chewing, etc.) and muscular balance (facial muscles, etc.) in the child.
- Trial name
- NCT07127328
- Testing
- Patient with removable funcitonal appliance
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Maxillary Expansion, Forensic Dentistry
Evaluation of Palatal Rugae-Based Identification After Maxillary Expansion Using Local Morphological Patch Analysis
This study investigates the reliability of palatal rugae-based identification following maxillary expansion procedures, including Miniscrew-Assisted Rapid Palatal Expansion (MARPE) and Surgically Assisted Rapid Maxillary…
- Conditions
- Maxillary Expansion, Forensic Dentistry, Intraoral Scanner, Orthodontic Appliance
- Trial name
- NCT07667933
- Testing
- SARME, MARPE, Untreated Control
- Where
- Hungary
- Volunteers
- 45 people
- Sponsor
- Semmelweis University
Malocclusion, Angle Class II, Overbite (Excessive) Horizontal
Long-term Stability of Treatment With the Twin Block Appliance
The objective of this observational study is to investigate the long-term stability of treatment with the Twin block appliance in a patient group previously treated with a Twin block appliance.
- Conditions
- Malocclusion, Angle Class II, Overbite (Excessive) Horizontal, Overbite (Excessive) Deep, Treatment Outcome
- Trial name
- NCT07752498
- Where
- Sweden
- Volunteers
- 72 people
- Sponsor
- Region Jönköping County
Fixed Orthodontic Retainer, Orthodontic Appliances, Removable
Bacterial Diversity Study Using 16S rRNA Sequencing of Periodontal Samples From Patients With Orthodontic Retainers
After completion of orthodontic treatment, a retention phase is required to prevent relapse of tooth malposition. Fixed retention in the mandibular anterior region is commonly used.
- Conditions
- Fixed Orthodontic Retainer, Orthodontic Appliances, Removable, Orthodontic Appliance Complication, Gingivitis
- Trial name
- Ortho-Perio (NCT07718061)
- Testing
- Fixed Orthodontic Retainer, Removable Essix-Type Orthodontic Retainer
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Universidad de Murcia
Traumatic Oral Ulceration, Orthodontic Treatment
Comparison of Hyaluronic Acid and Chlorhexidine Gels for Traumatic Oral Ulcers During Fixed Orthodontic Treatment
This randomized controlled trial aims to compare the effectiveness of topical hyaluronic acid gel and chlorhexidine gel in the management of traumatic oral ulcers that develop following placement of fixed orthodontic appliances.
- Conditions
- Traumatic Oral Ulceration, Orthodontic Treatment, Orthodontic Appliances, Fixed, Oral Mucosal Ulceration
- Trial name
- HYCHO-TOU (NCT07709455)
- Testing
- Hyaluronic Acid gel, Chlorhexidine gel
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Dow University of Health Sciences
Orthodontic Appliance Complication
Evaluation of Maxillary Buccal Miniscrew Insertion Using Digital Guides
This randomized split-mouth clinical trial aims to compare the accuracy and clinical outcomes of CAD/CAM 3D-printed surgical guides with the conventional free-hand technique for orthodontic miniscrew placement in the posterior…
- Trial name
- NCT07698730
- Testing
- CAD/CAM 3D-Printed Surgical Guide, Free-Hand Orthodontic Miniscrew Placement
- Where
- Vietnam
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Can Tho University of Medicine and Pharmacy
White Spot Lesions, Orthodontic Appliance Complication
Comparison of MI Paste Plus and Resin Infiltration in White Spot Lesions Following Orthodontic Treatment
Dental cavities are among the most frequent diseases that affect teeth, particularly in patients who are treated with braces due to the difficulty in maintaining good oral hygiene in the presence of the mouth appliances.
- Conditions
- White Spot Lesions, Orthodontic Appliance Complication, Caries Arrested, Smooth Surface Caries
- Trial name
- NCT05733676
- Testing
- Resin infiltration, Casein Phosphopeptide (CPP) - Amorphous Calcium Phosphate (ACP) - Fluoride
- Where
- Canada
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Orthodontic Appliance
Comparison of the Effectiveness of Three Teaching Methods in Oral Hygiene in Adolescent Orthodontic Patients
Orthodontic appliances have been shown to interfere with oral hygiene maneuvers by providing many additional sites for formation and retention of biofilm.
- Trial name
- MAHO (NCT04444154)
- Testing
- Control group, Group with active participation, Group with video and quizz
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Rennes University Hospital
Orthodontic Appliance Complication
Effect of Clear Aligner Attachment Size on Extrusion of Maxillary Lateral Incisors
Orthodontic treatment has been revolutionized by clear aligner therapy, offering patients a more esthetic and comfortable alternative to traditional braces. In 1999, Align Technology introduced Invisalign.
- Trial name
- NCT06814262
- Testing
- Corresponding treatment order in the prescription with Align Technology, Superimposition of final and initial positions of lateral incisors: Predicted model, Superimposition of final and initial positions of lateral incisors: Gingivally beveled 1x1x3mm aligners
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Virginia Commonwealth University
Orthodontic Appliances, Removable, Dental Plaque
Cleaning Methods for Clear Aligners
The goal of this clinical trial is to learn which cleaning method best removes bacteria from clear plastic aligners. Clear aligners are removable orthodontic trays worn to straighten teeth.
- Conditions
- Orthodontic Appliances, Removable, Dental Plaque, Biofilms, Disinfection
- Trial name
- NCT07610603
- Testing
- Toothbrushing of clear aligner with water, Chlorhexidine gluconate 0.2% oral rinse, Effervescent aligner cleaning tablet
- Where
- Saudi Arabia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Orthodentic Appliances, Orthodontic Pathological Resorption of External Root
Comparative Outcomes of Damon Ultima vs Pitts 21 Pro Bracket Systems
Title Comparative Evaluation of Treatment Outcomes between Damon Ultima and Pitts 21 Pro Bracket Systems; A Randomized Clinical Trial Abstract Background: The primary advantages of self-ligation brackets include faster archwire…
- Conditions
- Orthodentic Appliances, Orthodontic Pathological Resorption of External Root, Orthodontic Pain, Orthodontic Brackets
- Trial name
- NCT07318623
- Testing
- Treatment outcome of Damon ultima, Treatment outcome of pitt21 pro
- Where
- 2 sites in Iraq
- Volunteers
- 40 people
- Sponsor
- University of Baghdad
Orthodontic Appliances, Adverse Effects,Gingivitis, Dental Plaque, Periodontal Diseases
Digital Manufacturing and Periodontal Performance of CAD/CAM-Customized Orthodontic Molar Bands Compared With Standard Stainless-Steel Bands
his prospective randomized clinical trial aimed to compare periodontal outcomes associated with CAD/CAM-customized orthodontic molar bands and conventional preformed stainless-steel molar bands in adolescents undergoing fixed…
- Trial name
- NCT07526805
- Testing
- Stainless-Steel Orthodontic Molar Bands
- Where
- Romania
- Volunteers
- 180 people
- Sponsor
- Dimitrie Cantemir University
Orthodontic Appliance Complication
Effect of Local Subperiosteal Zoledronic Acid Injection on the Survival of Orthodontic Miniscrews
Background: Orthodontic miniscrews are widely used as temporary anchorage devices; however, failure remains a clinical concern. Bisphosphonates may enhance bone stability, but evidence on their local application is limited.
- Trial name
- NCT07546058
- Testing
- Zoledronic Acid, Normal saline (0.9% sodium chloride)
- Where
- Syria
- Volunteers
- 68 people
- Sponsor
- Latakia University
Dental Caries, Streptococcus Mutans
Effect of MI Paste Plus™ on Streptococcus Mutans and White Spot Lesions in Fixed Orthodontics
Background This study is part of a doctoral research project at Universidad Cardenal Herrera CEU (Spain), directed by Prof. Santiago Arias de Luxán and conducted by doctoral candidate Shirli Kelmendi within the PhD program in…
- Conditions
- Dental Caries, Streptococcus Mutans, Tooth Demineralization, Orthodontic Appliances, Fixed
- Trial name
- MIPASTEORTHO (NCT07244991)
- Testing
- MI Paste Plus (CPP-ACP with Sodium Fluoride)
- Where
- 2 sites in Albania
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Orthodontic Appliance, Pain
The Effect of Intraoral Transcutaneous Electrical Nerve Stimulation in Orthodontics Pain
The goal of this clinical trial is to determine whether an intraoral Transcutaneous Electrical Nerve Stimulation (TENS) device can reduce pain during orthodontic alignment and leveling in adolescents and adults.
- Conditions
- Orthodontic Appliance, Pain, Transcutaneous Electric Nerve Stimulation, Orthodontic Appliance Complication
- Trial name
- NCT06573996
- Testing
- Active TENS Device
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of the Pacific
Orthodontic Appliance
Comparison of Two Miniscrew Bone-borne Expanders (2 vs 4 Screws) Versus Conventional Hyrax Expander in Adolescents
Rapid maxillary expansion (RME) is used to correct transverse deficiencies of the maxilla. This randomized controlled trial compares three RME devices in adolescents (age 10-15) with at least 8 mm maxillary transverse deficiency…
- Trial name
- NCT07404488
- Testing
- Miniscrew supported expander application, 4 miniscrews supported rapid maxillary expansion application, Conventional tooth-borne Hyrax expander (comparator)
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- University of Roma La Sapienza
Myofunctional Therapy, Orthodontic Appliance
Assessment of Craniofacial and Postural Changes Induced by LM-Activator Therapy in Growing Children
This prospective study will compare the effects of LM-Activator™ and Twin Block appliances in 26 children (aged 8-13 years) with Class II malocclusion.
- Conditions
- Myofunctional Therapy, Orthodontic Appliance, Malocclusion Class II
- Trial name
- NCT07382011
- Testing
- LM-Activator™, Twin Block Appliance
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Marmara University
Orthodontic Appliance Complication, Plaque, Dental
Regular Home Use of Dual-light Photodynamic Therapy on Oral Health in Adolescents Undergoing Fixed Orthodontic Treatment
This study is designed to determine the efficacy of the Lumoral method on oral health in adolescents undergoing fixed orthodontic treatment.
- Conditions
- Orthodontic Appliance Complication, Plaque, Dental, Gingival Inflammation
- Trial name
- NCT05825742
- Testing
- Lumoral Treatment, Standard oral health instructions
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Koite Health Oy
Tooth Demineralization, White Spot Lesion
Comparison of a 3-step Bonding System (Transbond™ XT) and a 2-step System (GC Ortho Connect™) on Demineralization Around Maxillary Orthodontic Brackets
White spot lesions (WSLs) are one of the most common adverse effects of fixed orthodontic treatments, affecting up to 97% of patients treated with labial appliances.
- Conditions
- Tooth Demineralization, White Spot Lesion, Demineralization, Orthodontic Appliance Complication
- Trial name
- ORTHOCOLLAGE (NCT07355322)
- Testing
- Transbond™ XT bonding procedure, GC Ortho Connect™ bonding procedure
- Where
- France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Montpellier