Clinical trials: Orthodontic Brackets
Tooth Demineralization, White Spot Lesion
Comparison of a 3-step Bonding System (Transbond™ XT) and a 2-step System (GC Ortho Connect™) on Demineralization Around Maxillary Orthodontic Brackets
White spot lesions (WSLs) are one of the most common adverse effects of fixed orthodontic treatments, affecting up to 97% of patients treated with labial appliances.
- Conditions
- Tooth Demineralization, White Spot Lesion, Demineralization, Orthodontic Appliance Complication
- Trial name
- ORTHOCOLLAGE (NCT07355322)
- Testing
- Transbond™ XT bonding procedure, GC Ortho Connect™ bonding procedure
- Where
- France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Montpellier
Inflammation, Oxidative Stress
Oxidative-reductive Processes and the Degree of Inflammation in Saliva With Conventional Brackets and Clear Aligners
The purpose of this prospective observational study is to evaluate the differences in oxidative-reductive processes and the degree of inflammation in saliva during treatment with conventional brackets and clear aligners.
- Conditions
- Inflammation, Oxidative Stress, TNF-α
- Trial name
- NCT06507592
- Testing
- Saliva samples collection
- Where
- Italy
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Campania Luigi Vanvitelli
Orthodontic Pathological Resorption of External Root, Complication of Personal Oral Hygiene
Comparison of Oral Hygiene & Root Resorption During Orthodontic Treatment
Orthodontic treatment has been traditionally carried out with fixed appliances involving the use of stainless steel brackets and archwires.
- Trial name
- RCT (NCT02745626)
- Testing
- Appliance
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- UConn Health
Malocclusion
0.018 or 0.022 Bracket Slot System More Effective in Orthodontic Treatment?
The purpose of this study is to compare the 0.018-inch and 0.022-inch bracket slot systems to determine which is more effective for orthodontic treatment .
- Trial name
- 18v22 (NCT02080338)
- Testing
- Orthodontic bracket slot system
- Where
- 3 sites in United Kingdom
- Volunteers
- 187 people
- Sponsor
- David Bearn
Dental Malocclusion
Eighteen-month Orthodontic Bracket Survival Rate With the Conventional Bonding Technique Versus RMGIC and V-prep
The aim of this study was to evaluate over eighteen months the clinical bonding failure and survival rates of the conventional bonding technique using the Transbond XT (3M Unitek, Monrovia, California, USA) and the RMGIC Fuji…
- Trial name
- NCT05939102
- Testing
- v-prep combined with RMGIC for bracket bonding, Conventional bracket bonding technique
- Where
- Lebanon
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Orthodontic Appliance Complication
Assessment of Pain When Removing Metallic Brackets for Orthodontic Patients Using Two Removal Methods
Patients at the Orthodontic Department of the University of Damascus Dental School will be examined, and subjects who meet the inclusion criteria will be included.
- Trial name
- NCT06873503
- Testing
- Bracket removal using a Weingart plier with the mouth open, Biting on a cotton roll during brakcet removal
- Where
- Syria
- Volunteers
- 36 people
- Sponsor
- Damascus University
Tooth Discoloration
Bleaching Procedures Performed During Treatment With Brackets and Clear Aligners
The aim of this study is to compare the effectiveness of different whitening methods used during orthodontic treatment with fixed appliances and clear aligners.
- Trial name
- NCT06716827
- Testing
- In-office bleaching system, Laser-assisted bleaching, Home-bleaching
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Ahmet Yağcı
PAIN
COMPARISON OF THE PERCEPTION OF PAIN BETWEEN ORTHODONTIC TREATMENT WITH Invisalign ® AND TREATMENT WITH BRACKETS
This study aims to compare the pain experienced by patients undergoing orthodontic treatment with Invisalign ® corrective aligners with that of patients undergoing orthodontic treatment with conventional braces.
- Trial name
- NCT01855113
- Testing
- Invisalign
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- Université de Montréal
Enamel Demineralization, White Spot Lesions
Silver Nanoparticle-Coated Orthodontic Brackets for Preventing Enamel Demineralization
The goal of this clinical trial is to learn whether orthodontic brackets coated with silver nanoparticles can help prevent early damage to tooth enamel in people receiving fixed braces.
- Trial name
- AgBracket (NCT07707336)
- Testing
- Silver Nanoparticle-Coated Stainless Steel Orthodontic Brackets, Conventional Stainless Steel Orthodontic Brackets
- Where
- United Arab Emirates
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ajman University
Orthodontic Tooth Movement
Evaluation of the Rate of Maxillary En-masse Retraction Using 0.018-inch Versus 0.022-inch Slot Brackets in Adults
The study compares the rate of en-masse retraction using 0.018-inch versus 0.022-inch slot orthodontic bracket systems in adult patients with maxillary dentoalveolar protrusion.
- Trial name
- NCT04468295
- Testing
- Bonding, Leveling and alignment, Extraction
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Halitosis, Oral Hygiene
Impact of Bracket Design and Oral Hygiene Maintenance on Halitosis in the Orthodontic Patient
The advantage of self-ligating brackets on periodontal health has yet to be determined. In addition, the utilization of tongue scraping as an adjunct to traditional oral hygiene measures has yet to be studied in orthodontic…
- Trial name
- NCT01948349
- Testing
- Tongue scraping, Bracket design
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- UConn Health
White Spot Lesion
Effect of CO2 Laser on Enamel White Spot Lesion Formation Around Orthodontic Brackets
This study aims to evaluate the clinical effect of CO2 laser on enamel resistance to white spot lesions formation around orthodontic brackets.
- Trial name
- NCT03114475
- Testing
- CO2 laser irradiation
- Where
- 2 sites in Syria
- Volunteers
- 25 people
- Sponsor
- Damascus University
Malocclusion
Probiotic Lozenge Reduce Streptococcus Mutans in Plaque in Orthodontic Bracket Patients
Advances in orthodontics have improved the quality of appliances and treatment protocols, raising the standard of patient care. However, enamel demineralization is still a problem associated with orthodontic treatment, leading to…
- Trial name
- NCT02357771
- Testing
- Probiotic (L. brevis CD2 lozenges)
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Next Gen Pharma India Pvt. Ltd.
White Spot Lesion of Tooth, Long Term Adverse Effects
Comparison of Efficacy Of Probiotic Toothpaste and Chlorhexidine Mouthwash To Reduce S.Mutans
Orthodontic appliance causes increase in plaque accumulation, especially around brackets, wires and attachments. Advances in orthodontics in recent time have led to improved quality of appliance and treatment procedures…
- Conditions
- White Spot Lesion of Tooth, Long Term Adverse Effects, Caries, Dental, Orthodontic Appliance Complication
- Trial name
- NCT03004196
- Testing
- Probiotic Toothpaste, Dr. Reddy's Clohex, Control Group
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peoples University, Bhanpur, Bhopal
White Spot Lesion of Tooth
Remineralization Agents for the Treatment of White Spot Lesions
Clinically, formation of white spots can occur as early as 4 weeks into orthodontic treatment and very common in high caries risk individuals.
- Trial name
- NCT04827966
- Testing
- Clinpro® 5% sodium fluoride plus tri calcium phosphate varnish, Tooth Mousse® - Casein phosphopeptide-Amorphous calcium phosphate (CPP - ACP)s, MI Paste® -Casein phosphopeptide-Amorphous calcium phosphate fluoride (CPP-ACPF)
- Where
- Bahrain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Bahrain
Bracket Bonding
Orthodontic Bracket Bonding
Accurate bracket positioning is crucial for effective fixed orthodontic treatment and a core component of orthodontic specialist training. Clinically, two main bonding techniques exist: direct and indirect.
- Trial name
- OBB (NCT06685614)
- Testing
- orthodontic bracket bonding
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Temporomandibular Joint Disorders
Impact of Orthodontic Treatment on the Temporomandibular Joints (TMJ) Assessed by Modjaw
The aim of the study is to assess the correlation between orthodontic treatment and temporomandibular joint (TMJ). For that, an evaluation with a virtual articulator (Modjaw) is carried out before and after the treatment.
- Trial name
- EMDJW (NCT05710952)
- Testing
- Review by Modjaw
- Where
- France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Montpellier
Dental Bonding, Orthodontic Brackets
Segmented Indirect Versus Direct Bracket Bonding
This randomized clinical trial compared two methods of attaching orthodontic brackets to teeth: conventional direct bonding, in which each bracket is placed and bonded individually in the mouth, and a segmented modified indirect…
- Trial name
- NCT07861178
- Testing
- Direct bonding, Segmented modified indirect bonding
- Where
- Saudi Arabia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Periodontal Inflammation, Dental Malocclusion
Periodontal Parameters in Orthodontic Patients With Stainless Steel and Ceramic Brackets.
The aim of this study is to assess if there are significant differences in periodontal conditions between patients undergoing fixed orthodontic treatment with stainless steel or ceramic brackets.
- Trial name
- NCT05144555
- Testing
- Fixed orthodontic treatment with stainless steel brackets, Fixed orthodontic treatment with ceramic brackets
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Crowding
Treatment of Crowding Without Extraction Using Self Ligating Brackets
This experimental study will evaluate the effect of active and passive self-ligating brackets in treatment of crowding, compared with the control group of conventional brackets in class I malocclusion without extraction.
- Trial name
- NCT02996292
- Testing
- Traditional brackets, Active self-ligating brackets, Passive self-ligating brackets
- Where
- Syria
- Volunteers
- 60 people
- Sponsor
- Damascus University