Clinical trials: Orthopedic
General Surgery, Orthopedic Procedures
Implementing Virtual Reality in the Operating Room
"Recently, virtual reality has become more accessible thanks to the use of smaller, more comfortable and easier-to-use devices. Its use in operating theatres is growing.
- Trial name
- IRVABO (NCT06333639)
- Testing
- orthopaedic surgery, orthopaedic surgery and fitted with a virtual reality headset
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Osteoarthritis, Knee
A Single Time-Point Study to Evaluate the ConforMIS iTotal (PS) Knee Replacement System Versus Off-the-Shelf
This study is designed to compare outcome data for patients who have recently undergone surgery with the iTotal® Posterior Stabilizing (PS) Knee Replacement System (hereafter referred to as the "iTotal") versus those who have…
- Trial name
- NCT03146819
- Testing
- iTotal PS Knee Replacement System, Off-the-Shelf Knee Replacement System
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Restor3D
Pain, Postoperative
Monitoring Postoperative Pain and Recovery Following Orthopedic Surgery
This pilot study will seek to use emotion recognition technology from video to link patient facial expressions, heart rate and respiratory rate changes, and movement patterns to patient pain scores.
- Trial name
- NCT02316951
- Testing
- single-arm study group
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Florida
Musculoskeletal Injury Trauma
An Integrated-Delivery-of-Care Approach to Improve Patient Outcomes, Safety, Well-Being After Orthopaedic Trauma
Orthopedic trauma is an unforeseen life-changing event. Nearly 2.8 million Americans sustain traumatic orthopedic injuries such as major fractures or amputation each year.
- Trial name
- NCT02591472
- Testing
- Integrated care (ICare), Usual Care (UsCare), Patient-Reported Outcomes Measurement Information System
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of Florida
Anxiety State
Augmented Reality Perioperative Training and Patient Satisfaction
The purpose of this study is to learn more about how augmented reality systems can influence perioperative experience and patient satisfaction.
- Trial name
- NCT04727697
- Testing
- Augmented Reality, Standard of Care preoperative teaching and handouts
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- University of Miami
Fracture, Fracture Nonunion
Relationships Between Vitamin D and Orthopedic Trauma
Vitamin D is an essential hormone involved in bone metabolism, bone mineral density maintenance, and bone health. Vitamin D deficiency is putatively linked to poor pediatric orthopedic outcomes [1].
- Conditions
- Fracture, Fracture Nonunion, Fractures, Bone, Vitamin D
- Trial name
- NCT04564625
- Testing
- Vitamin D Assessment, Fracture
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Methodist Health System
Orthopedic Disorder
Parental Perceptions on Prescription Opioid Use
This study involves an anonymous survey given to parents regarding their perceptions on prescription opioid use for pain control in children undergoing orthopedic surgery.
- Trial name
- NCT05344118
- Testing
- Survey
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Nationwide Children's Hospital
Morquio Syndrome A, Maroteaux Lamy Syndrome
Screening an Orthopedic Population for Mildly-affected Individuals With Morquio Syndrome A and Maroteaux-Lamy Syndrome
The purpose of this study is to identify patients with Morquio syndrome type A (MPS IVA) and Maroteaux-Lamy syndrome (MPS VI) who may have been missed or misdiagnosed due to atypical clinical features, a milder course, and/or…
- Conditions
- Morquio Syndrome A, Maroteaux Lamy Syndrome, MPS IVA, MPS VI
- Trial name
- NCT01961518
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Greenwood Genetic Center
Shoulder Arthroscopy, Knee Arthroscopy
Oral Clonidine & Gabapentin: Improving Recovery and Pain Management After Outpatient With Major Orthopedic Surgery
The purpose of this research is to investigate the non-opioid (non-narcotic) pain-relieving medications clonidine and gabapentin to see if they decrease the amount of opioid pain medications needed after surgery, thereby reducing…
- Trial name
- NCT01112878
- Testing
- Sugar pill, Gabapentin, Clonidine
- Where
- United States
- Sponsor
- Cedars-Sinai Medical Center
Postoperative Pain, Rebound Pain
Nerve Block Resolution Time Display and Pain Complaints
This randomized prospective study will evaluate whether displaying the expected nerve block resolution time on a patient's splint reduces postoperative pain-related complaints after orthopedic surgery.
- Conditions
- Postoperative Pain, Rebound Pain, Fracture
- Trial name
- NCT07887516
- Testing
- Physical display
- Volunteers
- 128 people
- Sponsor
- Medical University of South Carolina
Heart Failure
Paracrine Mechanisms of Bone Marrow Stem Cell Signalling in Chronic Heart Failure
The investigators hypothesize that chronic heart failure is associated with a general stem cell dysfunction, which translates into reduced paracrine function of adult stem cells from patients with chronic heart failure as…
- Trial name
- BM-CHF (NCT01086787)
- Testing
- Surgery
- Where
- 2 sites in Italy, Netherlands
- Volunteers
- 125 people
- Sponsor
- University Medical Center Groningen
Tourniquets, Knee Arthroplasty, Total
Tourniquet Pressure in Primary Total Knee Arthroplasty
This proposed novel randomized control trial (RCT) seeks to address this gap in TKA protocol by gaining a better understanding of the relationship between tourniquet pressure and time, and intraoperative performance and…
- Conditions
- Tourniquets, Knee Arthroplasty, Total, Knee Replacement, Total
- Trial name
- NCT02830087
- Testing
- Tourniquet Cuff Pressure
- Where
- 2 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Post-operative Time Saving Techniques
Application Time of Plaster-of-Paris Splint Packs Compared to Bulk Supplies Following Standard Orthopaedic Procedure
The investigators wish to perform a randomized controlled study to determine how much time and money is saved by orthopedic foot and ankle surgeons through the use of prepared splint packs compared to bulk supplies.
- Trial name
- NCT01602484
- Testing
- Pre-prepared Splint Pack composed by Medline, Bulk splint supplies
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Brigham and Women's Hospital
Anxiety, Satisfaction
The Effect of Virtual Tour Training Before Orthopedic Surgery
The purpose of the study is to determine the effect of training on surgical environments provided with virtual tour before orthopedic surgical ıntervention on patients' anxiety and satisfaction level.
- Trial name
- NCT06936540
- Testing
- Virtual Tour, No Interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Istanbul University - Cerrahpasa
Pruritus
Gabapentin for Prophylaxis Intrathecal Morphine-Induced Pruritus
Intrathecal morphine provides good postoperative analgesia for up to 18-24 hour after administration. Pruritus is the most common side effect of intrathecal morphine, which the incidence was reported as 20%-100%2 and 63% in…
- Trial name
- NCT01236859
- Testing
- Gabapentin
- Where
- Thailand
- Volunteers
- 180 people
- Sponsor
- Prince of Songkla University
Pain, Nausea
A Controlled Study to Determine the Efficacy and Safety of CL-108 5 mg for Acute Pain and the Prevention of OINV
To determine the analgesic efficacy of CL-108 5 mg by comparison with placebo and the anti-emetic efficacy of CL-108 5 mg by comparison with hydrocodone 5 mg/acetaminophen 325 mg.
- Conditions
- Pain, Nausea, Vomiting
- Trial name
- NCT03657810
- Testing
- CL-108 5 mg, Norco
- Where
- 5 sites in United States
- Volunteers
- 349 people
- Sponsor
- Charleston Laboratories, Inc
Bone Metastases, Musculoskeletal Cancer
Aspirin and Compression Devices for VTE Prophylaxis in Orthopaedic Oncology
This is a research study to compare the efficacy of aspirin (acetylsalicylic acid) and pneumatic compression devices versus enoxaparin (also known as Lovenox) and pneumatic compression devices in preventing deep vein thrombosis…
- Conditions
- Bone Metastases, Musculoskeletal Cancer, Soft Tissue Sarcoma, Thromboembolism
- Trial name
- NCT01696760
- Testing
- acetylsalicylic acid, enoxaparin, PCD
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Degenerative Osteoarthritis, Degenerative Lumbar Vertebra
Efficacy and Safety Study of Lumbar Interbody Fusion With MatriTMBONE Associated With Autologous Bone Marrow
The main objective of this clinical study is the estimation of the rate of intersomatic fusion observed 12 months after lumbar interbody fusion by posterior approach with PEEK interbody cage of fusion in PEEK performed with…
- Trial name
- MatriBone (NCT01335243)
- Testing
- The Transforaminal Lumbar Interbody Fusion (TLIF) surgery
- Where
- France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Bordeaux
Post Operative Pain
Post Operative Infusion Pump Pain Study
This study will be a pragmatic, prospective cluster randomized trial, where clusters will formed based on sequential 2 week time increments across the study recruitment period..
- Trial name
- NCT07349810
- Testing
- Bupivacaine 0.5% Injectable Solution, Ropivacaine 0.2% Injectable Solution, 1.3% liposomal bupivacaine (Exparel)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Rutgers, The State University of New Jersey
Knee Surgery, Shoulder Surgery
Changes in Anthropometry Following Ambulatory Orthopaedic Surgery
The purpose of this research is to study changes in weight, body mass index, and percentage of fat following orthopaedic knee or shoulder surgery.
- Trial name
- CAS (NCT02435251)
- Testing
- dual energy X-ray absorptiometry
- Where
- United States
- Sponsor
- State University of New York at Buffalo