Clinical trials: Osteopenia, Generalized
Chronic Rhinosinusitis Without Nasal Polyps, Asthma
Adherence in Global Airways - Steroid Intake and Effects on Chronic Rhinosinosinutis
The purpose of this study is to investigate the relationship between long-term use of systemic steroids in patients with upper and lower respiratory tract diseases and their own production of cortisol (cross-sectional), as well…
- Conditions
- Chronic Rhinosinusitis Without Nasal Polyps, Asthma, Chronic Rhinosinusitis With Nasal Polyps, Steroid-Induced Osteopenia (Diagnosis)
- Trial name
- AGAS 2023 (NCT05843019)
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Christiane Haase
Postmenopausal Osteopenia
The Effect of Aerobic Exercise on Bone Turnover Markers in Postmenopausal Patients
The aim of the study was to evaluate the effect of light-moderate aerobic exercise on BMD in postmenopausal osteopenic women using bone formation-resorption markers.
- Trial name
- NCT06866561
- Testing
- aerobic exercise, cholecalciferol, calcium carbonate
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Low Bone Density, Osteopenia
Safety and Pharmacokinetics of Orally Administered Strontium L-Lactate in Healthy Adults
No clinical trials have evaluated strontium L-lactate (SrLac), the strontium salt of the L-enantiomer of lactic acid. Therefore, this clinical study was conducted to obtain general safety and pharmacokinetic (PK) information…
- Conditions
- Low Bone Density, Osteopenia, Osteoporosis, Postmenopausal
- Trial name
- NCT03761979
- Testing
- Strontium L-lactate
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- BioLink Life Sciences, Inc.
Low Bone Density
Age Related Changes in Calciotropic Hormones and Their Impact on Male Osteoporosis
The purpose of this pilot study is to generate preliminary data regarding the skeletal effects of age-related changes in calcium and vitamin D metabolism in older men.
- Trial name
- NCT00588874
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Yale University
Hypogonadism, Osteopenia
Testosterone and Alendronate in Hypogonadal Men
This study will investigate the hypothesis that the combination of testosterone replacement and alendronate will improve bone density and parameters of bone quality more than either medication alone in older men with low…
- Conditions
- Hypogonadism, Osteopenia, Osteoporosis
- Trial name
- NCT01460654
- Testing
- Testosterone, Alendronate
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Osteopenia
Effect of Whole-Body Vibration on Plasma Sclerostin Level
The aim of this study is to investigate effect of whole-body vibration on plasma sclerostin level in healthy young adult women. Fifteen healthy young adult women are planned to include in this study.
- Trial name
- WBV-SCL (NCT01310335)
- Testing
- whole-body vibration (WBV)
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Bagcilar Training and Research Hospital
Osteopenia
A First-in-human Study Evaluating Romosozumab (AMG 785) in Healthy Men and Postmenopausal Women
The primary objective of this study is to assess the safety and tolerability of romosozumab following single dose subcutaneous (SC) or intravenous (IV) administration in healthy men and postmenopausal women.
- Trial name
- NCT01059435
- Testing
- Romosozumab
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Amgen
Post-Menopausal Osteoporosis, Post-Menopausal Osteopenia
Vitamin K Supplementation in Post-Menopausal Osteopenia
The purpose of this study is to determine whether supplementation with 5 mg vitamin K daily over a 2-year period will prevent bone loss in post-menopausal women with osteopenia.
- Trial name
- NCT00150969
- Testing
- vitamin K1 (phylloquinone)
- Where
- 5 sites in Canada
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Osteopenia
The Effect of Lactobacillus Reuteri ATCC PTA 6475 on Volumetric Bone Mineral Density in Patients With Osteopenia
Lactobacillus reuteri (L. reuteri) has been widely studied in clinical trials and has probiotic, health-promoting effects in both adults and children, and is safe for human consumption.
- Trial name
- NCT02422082
- Testing
- L. reuteri
- Where
- Sweden
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sahlgrenska University Hospital
HIV Infections, HIV-Associated Lipodystrophy Syndrome
A Study of Physical and Metabolic Abnormalities in HIV Infected and Uninfected Children and Youth
The purpose of this study is to assess the prevalence of metabolic and physical abnormalities in HIV infected (via mother-to-child transmission) and uninfected children and youth.
- Conditions
- HIV Infections, HIV-Associated Lipodystrophy Syndrome, HIV Lipodystrophy Syndrome, Lipodystrophy
- Trial name
- NCT00069004
- Where
- 38 sites in United States, Puerto Rico
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Osteoporosis, Osteopenia
Encouraging Calcium Absorption and Bone Formation During Early Puberty
Increasing bone mass during puberty can ultimately decrease the risk of developing osteoporosis, which causes bones to weaken and break more easily later in life.
- Trial name
- NCT00022867
- Testing
- Nondigestible oligosaccharide (NDO)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Osteopenia
Effects of Whole Body Vibration (WBV) on Musculoskeletal System of Aged Women
A controlled, non-randomized trial will be carried out in 240 postmenopausal women, aged 55-75 years, over a 18-month period. The group 1 received a physical intervention, consisting of whole body vibration (WBV) over 12 months…
- Trial name
- VIBROS (NCT01982214)
- Testing
- sedentary, Vibration
- Where
- France
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Osteopenia, Sarcopenia
Effect of Electromyostimulation on Bone
Although there is some evidence that whole body electromyostimulation(WB-EMS) affect bone via its acute and longitudinal effects on muscle mass and strength, the corresponding impact on bone density and falls in older adults has…
- Conditions
- Osteopenia, Sarcopenia, Falls
- Trial name
- NCT01296776
- Testing
- wellness control group., whole-body electromyostimulation
- Where
- Germany
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Osteoporosis, Osteopenia
Effect of Dried Plum on Bone and Markers of Bone Status in Men
The principal objective of this study is to examine whether the addition of 100 g dried plum to the diets of men, regardless of their bone status, positively influences their indices of bone turnover in comparison with their…
- Trial name
- NCT04720833
- Testing
- dried plum, Calcium and vitamin D
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Osteoporosis, Postmenopausal, Osteoporosis, Osteopenia
Effects of Physical Exercise to Prevent Osteoporosis in Postmenopausal Women
According to the World Health Organization criteria, osteoporosis was defined as a bone mineral density that lies 2.5 standard deviations or more below the average value for young healthy women.
- Conditions
- Osteoporosis, Postmenopausal, Osteoporosis, Osteopenia, Physical Activity
- Trial name
- Osteo_women (NCT03091088)
- Testing
- walking at an intense pace, osteoporosis specific-oriented training
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Osteopenia, Osteopenia of the Elderly
A Clinical Trial Investigating the Effect of Salmon Bone Meal on Bone Mass Among Osteopenic Women
The purpose of this study is to evaluate the efficacy of salmon bone meal in preventing bone loss among perimenopausal women with reduced bone mass density.
- Trial name
- NCT05066477
- Testing
- CalGo
- Where
- 3 sites in Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hofseth Biocare ASA
Osteoporosis
Assessment of Bone Micro-Architecture Using HR-pQCT
In the context of male osteoporosis, we hypothesize that regional changes in trabecular bone, as well as changes in cortical porosity will play a major role, and thus also affect bone strength.
- Trial name
- NCT01367730
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Periodontal Disease
Effect of Actonel on Periodontal Health of Postmenopausal Women
Hypothesis: Women who use Actonel (risedronate) for osteopenia will show beneficial periodontal effects.
- Trial name
- NCT00594334
- Testing
- Risedronate
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Sarcopenia, Osteopenia
Exercise Effects on Sarco-Osteopenia in Older Men
The study determined the effects of predominately resistance type exercise in combination with protein supplements on parameters of sarcopenia and osteopenia (sarco-osteopenia) in older, community dwelling men with sarcopenia and…
- Trial name
- NCT03453463
- Testing
- exercise
- Where
- Germany
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Osteoporosis, Osteopenia
Melatonin-Micronutrients for Osteopenia Treatment Study
The investigators' long-term goal is to employ novel methods to improve bone formation and bone density in women (and men) with osteopenia or osteoporosis while also decreasing signs and symptoms of degenerative joint and disc…
- Trial name
- MOTS (NCT01870115)
- Testing
- Fiber Pill, Melatonin, Strontium citrate, Vitamins D3 and K2
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Duquesne University