Clinical trials: Osteoporosis, Postmenopausal
Osteoporosis
Effects of Proteins Fraction Derived From Milk on Osteoporosis Prevention
Osteoporosis is defined as a systemic skeletal disease characterised by low bone mass and microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility to fracture.
- Trial name
- NCT01478724
- Testing
- Milk proteins fraction
- Where
- France
- Volunteers
- 291 people, healthy volunteers welcome
- Sponsor
- Soredab
Postmenopausal Osteoporosis, Compliance
Clinical Study of Raloxifene and Strontium Ranelate in Postmenopausal Osteoporosis
The purpose of this study was to compare compliance and efficacy of raloxifene and strontium ranelate in a group of women with postmenopausal osteoporosis.
- Trial name
- NCT01544894
- Testing
- Raloxifene, Strontium ranelate
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Osteoporosis, Postmenopausal
A Study of Blosozumab (LY2541546) in Postmenopausal Female Participants
The purpose(s) of this study is to measure how much of the study drug gets into the blood stream and how long it takes the body to get rid of it when given in multiple doses, subcutaneously (SC) (by inserting a needle just under…
- Trial name
- NCT02109042
- Testing
- Blosozumab
- Where
- 2 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Postmenopausal Osteoporosis
Phase 1 Study to Compare CMAB807 Injection to Prolia® in Healthy Volunteers
CMAB807 is a human monoclonal antibody targeting the key bone resorption mediator RANKL. The drug is administered via subcutaneous injection once six months and is approved for various indications, including the treatment of…
- Trial name
- NCT03925051
- Testing
- Prolia®, CMAB807
- Where
- China
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Shanghai Biomabs Pharmaceutical Co., Ltd.
Postmenopausal Osteoporosis
Comparing of the Pharmacokinetic, Safety and Immunogenicity of HS-20090-2 Injection and Prolia® in Healthy Adults
A randomized, single-blind and parallel group study to compare the pharmacokinetic, safety and immunogenicity of HS-20090-2 60mg#1ml#and Prolia® in healthy adults.
- Trial name
- NCT04940845
- Testing
- HS-20090-2, Prolia
- Where
- China
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Shanghai Hansoh Biomedical Co., Ltd
Postmenopausal Osteoporosis, Postmenopausal Osteopenia
High Intensity Multi-Modal Exercise Training in Postmenopausal Women
in Pakistan 9.9 million people are osteoporotic and 7.2 million amongst them are women. Globally after every 3 seconds there is occurrence of fragility fracture.In Pakistan females carries different risk factors based on distinct…
- Trial name
- HIT-MMEX (NCT04653350)
- Testing
- High Intensity Exercises, General Exercises
- Where
- 2 sites in Pakistan
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Osteoporosis, Postmenopausal
Parameters of Exercise to Prevent Osteoporosis
The principal goal of this study is to determine parameters of walking in terms of peak mechanical vertical force, bout duration, and bout spacing that can preserve or increase bone mineral density (BMD) in postmenopausal women.
- Trial name
- OSTEOPOROSISEX (NCT04063813)
- Testing
- Experimental: 40 minute up trial, Experimental: 40 minute down trial, Experimental: Two 20 minute up trials
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Osteoporosis Fracture
Height Loss, Kyphosis Indicators, Bone Mineral Density and Vertebral Fractures in Chinese Postmenopausal Women
This is an observational and cross-sectional study on the height loss, kyphosis indicators, bone mineral density and vertebral fractures in Chinese postmenopausal women
- Trial name
- NCT03798444
- Testing
- dual energy X-ray absorptiometry, lateral spine imaging from T4 to L4 on X-ray
- Where
- China
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Central South University
Osteoporosis, Postmenopausal
A Study of 2 Different Formulations of Blosozumab (LY2541546) in Post Menopausal Women
The purpose of this study is to evaluate the tolerability of two different formulations of blosozumab in women who have reached menopause. This study will last approximately 12 weeks for each participant, not including screening.
- Trial name
- NCT02337387
- Testing
- Blosozumab
- Where
- 3 sites in United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Cardiovascular Diseases, Osteoporosis
A Study on the Impact of Calcium on Woman's Vascular Health
The overarching aim of this randomized clinical trial is to estimate the effect of dietary intake of calcium as compared to supplemental calcium on the vascular system and markers of vascular and bone health in postmenopausal…
- Trial name
- NCT01731340
- Testing
- Calcium Citrate, Low Dietary Calcium, High Dietary Calcium
- Where
- Canada
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Osteoporosis, Osteoporosis, Postmenopausal
3-Week Parathyroid Hormone-related Protein (PTHrP) Dose Escalation Study in Post-Menopausal Women
The main purpose of this study is to determine the safety and effectiveness of three week daily subcutaneous injections of Parathyroid Hormone-related Protein (1-36).
- Trial name
- NCT00222872
- Testing
- Parathyroid Hormone-related Protein
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Osteoporosis
A First-in-Human Study Evaluating AGA2118 in Men and Postmenopausal Women
The primary objectives of the study are to assess the safety and tolerability of AGA2118 after single subcutaneous or intravenous administration in healthy men and postmenopausal women and to assess the safety and tolerability of…
- Trial name
- NCT05225857
- Testing
- AGA2118
- Where
- 2 sites in Australia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Angitia Biopharmaceuticals
Osteopenia, Osteoporosis
The Effects of Bovine Colostrum in Bone Metabolism in Humans
Osteoporosis constitutes a major public health concern. For instance, in European Union 1 in 3 women and at least 1 in 6 men will suffer an osteoporotic fracture during their lifespan.
- Trial name
- NCT04040010
- Testing
- Colostrum supplementation for bone loss
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Petros Dinas
Osteoporosis
Tocotrienols and Bone Health of Postmenopausal Women
Osteoporosis (severe bone loss) is a bone disease with bone fragility and an increased chance for bone fractures. Recent studies have indicated tocotrienols (one kind of vitamin E) supplement may be good for the bone health in…
- Trial name
- NCT02058420
- Testing
- Low tocotrienols group, High tocotrienols group
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Postmenopausal Osteoporosis
Bone Modeling Effects of Combined Anabolic/Antiresorptive Administration
The purpose of this study is to examine, via iliac crest bone biopsies, the mechanism of combined teriparatide and denosumab on the bone of postmenopausal osteoporotic women after 3 months of treatment.
- Trial name
- NCT04026256
- Testing
- Teriparatide, Denosumab
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Osteoporosis
Green Tea and Tai Chi for Bone Health
Osteoporosis is a major health problem in postmenopausal women. Our long-term goal is to develop a new alternative treatment that include a dietary supplement (green tea extract) and a mind-body exercise (Tai Chi) for lessening…
- Trial name
- GTP-TC-Bone (NCT00625391)
- Testing
- Green Tea Polyphenols (GTP), GTP+TC
- Where
- United States
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Osteoporosis, Postmenopausal, Osteoporosis
Comparative Antiresorptive Efficacy Discontinuation of Denosumab
Osteoporosis remains a significant healthcare burden for the United States. Current FDA-approved osteoporosis treatments include teriparatide, abaloparatide, bisphosphonates, denosumab, and raloxifene.
- Trial name
- NCT03623633
- Testing
- denosumab, alendronate, raloxifene
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Osteoporosis, Diet Habit
Soft Drinks and Osteoporosis in WHI Participants
Osteoporotic fractures, as a consequence of a reduced mineral bone density (BMD) represents a major public health problem. The lifetime risk of fractures exceeds 40% for women and 13% for men.
- Trial name
- NCT03371433
- Testing
- Soft drinks
- Volunteers
- 79,885 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Healthy, Osteopenia
Resistance Training and Rapamycin to Enhance Bone Formation in Postmenopausal Women
The aim of the present clinical trial is to examine the effects of everolimus, resistance training, or their combination on bone and muscle health formation in elderly women aged 60-75 years.
- Conditions
- Healthy, Osteopenia, Osteoporosis Risk
- Trial name
- StrongBone (NCT07191353)
- Testing
- Everolimus, Resistance training
- Where
- 2 sites in Denmark
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Osteoporosis, Postmenopausal
Coral Calcium's Effect on Bone Density in Postmenopausal Women With and Without Ibandronate
This study will investigate the effect of coral calcium complex supplementation on BMD of osteoporotic individuals either when used alone or in combination with ibandronate.
- Trial name
- NCT04321837
- Testing
- Coral Complex 3, Ibandronate, Vitamin D3
- Where
- Armenia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Columbia University