Clinical trials: Outpatient Surgery
Outpatient Surgery, Abdominal Surgery
Pilot Trial: Postoperative Opioid-free Analgesia
North America is facing an opioid epidemic fueled by surgeons, who are the second largest subgroup of physicians involved in opioid prescribing.
- Conditions
- Outpatient Surgery, Abdominal Surgery, Breast Surgery
- Trial name
- NCT04254679
- Testing
- Opioid analgesics, Non-opioid analgesics
- Where
- Canada
- Volunteers
- 81 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Ambulatory Surgery, Coughing
Effect of Fentanyl on Coughing and Recovery After Anesthesia With an LMA Laryngeal Mask Airway)for Airway Management
The purpose of this research is to evaluate the effectiveness of fentanyl for reducing coughing during the perioperative period (i.e., insertion of an LMA [Laryngeal Mask Airway] device, maintenance period during surgery, and…
- Trial name
- LMA (NCT01368809)
- Testing
- Saline, Fentanyl
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Cedars-Sinai Medical Center
Pain
Use of Dexmedetomidine for Deep Sedation in Patients Undergoing Outpatient Hysteroscopic Surgery
Patients undergoing deep sedation for outpatient procedures typically receive a combination of benzodiazepines, propofol, and opioids.
- Trial name
- NCT01337739
- Testing
- Active Comparator
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- Northwestern University
Opioid Use
A Multimodal Analgesia Protocol Adapted for Ambulatory Surgery
The primary objective of this trial is to determine whether the combination of three non-opioid analgesics (multimodal analgesia) can significantly reduce or eliminate the need for opioids after ambulatory surgery.
- Trial name
- NCT04015908
- Testing
- Celecoxib, Acetaminophen, Pregabalin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Utah
Anxiety
Resistance Under the Microscope
The purpose of this study is to determine whether lorazepam, which is used to lower preoperative anxiety, also improves postoperative recovery.
- Trial name
- NCT01441843
- Testing
- Lorazepam, NaCl 0.9% (Sodium Chloride)
- Where
- Netherlands
- Volunteers
- 400 people
- Sponsor
- Erasmus Medical Center
Outpatient Surgery, Pain, Postoperative
Patient Narcotic Requirements After Outpatient Otolaryngology Procedures
Patient's pain level and narcotic requirements will be evaluated after routine outpatient Otolaryngology procedures. This will be done by having study participants record their pain level and medication usage from home.
- Trial name
- NCT03404518
- Testing
- Norco, Ibuprofen
- Where
- 2 sites in United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Surgery, Anesthesia
A Comparison of Desflurane vs. Sevoflurane and the Time to Awakening and the Incidence and Severity of Cough
Goals for ambulatory surgery include providing optimal surgical conditions while ensuring a rapid early recovery without side effect.
- Trial name
- NCT01202162
- Testing
- Desflurane, Administration of Sevoflurane
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Northwestern University
Inguinal Hernia
Determine the Clinical Advantage of IV vs PO Acetaminophen
There is limited research on the clinical outcome differences between intravenous (IV) acetaminophen versus oral (PO) acetaminophen.
- Trial name
- NCT03558555
- Testing
- Acetaminophen IV Soln, Oral Acetaminophen, Saline
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Yan Lai
Knee Arthroscopy
Assessing the Effects of Sublingual Sufentanil 30 µg on Postoperative Recovery
A pilot study to evaluate the effect of incorporating sublingual sufentanil into our perioperative opioid regimen for ambulatory orthopedic surgery.
- Trial name
- NCT04561375
- Testing
- Sufentanil, Fentanyl
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- The Cleveland Clinic
Pain
The Effect of Intraoperative Esmolol to Improve Postoperative Quality of Recovery and Pain After Ambulatory Surgery
Seventy percent of surgeries performed in the United States are done in an outpatient setting.Pain Control after ambulatory surgery is very challenging because patients do not have access to fast and potent intravenous…
- Trial name
- NCT01782898
- Testing
- Esmolol administered at a rate of 0.5 mg/kg followed by an infusion of 5-15 mcg/kg/min
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Northwestern University
Outpatient Breast Surgery, Mastopexy
Serratus Plane Block for Postoperative Pain Control
This is a randomized, double-blinded, placebo-controlled trial of serratus plane blocks in subjects undergoing outpatient unilateral or bilateral breast surgery.
- Conditions
- Outpatient Breast Surgery, Mastopexy, Augmentation, Revision
- Trial name
- NCT02865928
- Testing
- Bupivicaine HCl, Normal Saline
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Northwell Health
Anesthesia, Surgery
Comparison of Ambu Auragain and I-Gel Supraglottic Airways in Adult Patients at an Ambulatory Surgery Center
The purpose of this study is to determine if an I-gel laryngeal mask airway (LMA) has a higher oropharyngeal leak pressure compared to an Ambu Auragain in adult patients in an ambulatory surgery center.
- Trial name
- NCT04286581
- Testing
- I-Gel Laryngeal Mask Airway, Ambu Auragain Laryngeal Mask Airway
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- University of Minnesota
Pain, Pain, Acute
Sublingual Sufentanil vs Intravenous Fentanyl for Acute Pain in the Ambulatory Surgery Center
The purpose of this study is to determine if a single dose of sublingual sufentanil is as or more efficacious than a single dose of IV fentanyl in a post anesthesia care setting.
- Conditions
- Pain, Pain, Acute, Anesthesia
- Trial name
- NCT04177862
- Testing
- Sublingual Sufentanil, IV Fentanyl
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Minnesota
Pelvic Organ Prolapse, Urinary Incontinence,Stress
Timing of Repeat Voiding Trials After Outpatient Pelvic Floor Surgery
This study is a randomized controlled trial designed to assess the rate of failure of voiding trials in the early and late post-operative period within patients who underwent outpatient pelvic floor surgery that failed initial…
- Conditions
- Pelvic Organ Prolapse, Urinary Incontinence,Stress, Surgery
- Trial name
- NCT03048682
- Testing
- Foley catheter - Early Voiding Trial, Foley catheter - Late Voiding Trial
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- The Cleveland Clinic
Hypothermia
Comparison of Forced Air and Conductive Patient Heating Systems During Ambulatory Surgeries
Comparison of forced air and conductive warming devices in outpatient orthopaedic surgeries.
- Trial name
- NCT02467777
- Testing
- Bair Hugger, VitaHeat
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fox Valley Orthopedic Institute
Pain
Gabapentin as an Adjunct to Paracervical Block for Perioperative Pain Management
This is a randomized controlled trial of gabapentin 600 mg compared to placebo given 1-2 hours preoperatively in conjunction with perioperative paracervical block for surgical abortion.
- Trial name
- Gaba (NCT02944656)
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Emory University
Ambulatory Surgery
REducing Anxiety in CHildren Undergoing Procedures
This is a small pilot, feasibility study designed as a quality improvement project. The purpose is to identify anxiety in children aged 4-12 years who will receive a sedated procedure and to see if the use of an iPad as a focused…
- Trial name
- REACH-UP! (NCT03054077)
- Testing
- iPad with downloaded games
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Supracondylar Humerus Fracture
Supracondylar Humerus Fracture (SCHF) Post-Op Study Between Opioid and Non-Opioid Pain Management
This purpose of this study is to determine the efficacy of nonopioid versus opioid analgesic regimens following surgical fixation of Gartland Type III Supracondylar Humoral Fractures (SCHFs) to assist in the development of a…
- Trial name
- NCT06187584
- Testing
- Hydrocodone/acetaminophen, Acetaminophen, Ibuprofen
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Children's Mercy Hospital Kansas City
Post-operative Pain, Anesthesia
Methadone in Ambulatory Surgery
The μ-opioid receptor agonist methadone is frequently used in adult anesthesia and adult pain therapy. Methadone has an extremely long half-life, which confers therapeutic advantage by providing more stable plasma concentrations…
- Trial name
- NCT02300077
- Testing
- methadone, Control (Intra-operative administration of opioids, other than methadone)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Washington University School of Medicine
Pain, Rotator Cuff Injuries
Bridge Device for Surgical Pain for Rotator Cuff Surgery
The objective of the trial is to investigate the efficacy of the Bridge device in reducing post-operative pain and post-operative opioid consumption in patients undergoing rotator cuff surgery with the typical mode of anesthesia…
- Trial name
- NCT06071884
- Testing
- Bridge Percutaneous Nerve Field Stimulator
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Steven Orebaugh