Clinical trials: Ovarian Endometriosis
Endometrioma, Ovarian Endometriosis
Evaluation of Ovarian Reserve and Recurrence Rate After DWLS Diode Laser OMA Vaporization
PURPOSE OF THE STUDY The study aims to evaluate the effectiveness of the Dual Wavelength Laser System (DWLS) diode laser on the treatment of endometrioma (OMA), with ablation and vaporization of the cystic capsule without…
- Conditions
- Endometrioma, Ovarian Endometriosis, Ovarian Endometrioma
- Trial name
- OMAlaser (NCT06219044)
- Testing
- laparoscopic endometrioma laser vaporization
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Endometriosis, Ovarian Hyperstimulation
Assessment and Prevention of Pain During Ovarian Stimulation in Patients With Endometriosis
Randomized double blinded placebo-controlled trial to evaluate the impact of ovarian hyperstimulation on endometriosis-related symptoms and to evaluate the impact of letrozole use during ovarian hyperstimulation with respect to…
- Trial name
- APPOSE (NCT04002141)
- Testing
- Letrozole
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Endometriosis, Endometriosis Ovary
Menstrual Blood Proteomic Profile in Women With Endometriosis (PROTEO-ENDO) Study
In this prospective case control study a total of 66 women (33 women with endometriosis) and (33 healthy women) will be recruited.
- Conditions
- Endometriosis, Endometriosis Ovary, Endometriosis-related Pain
- Trial name
- PROTEO-ENDO (NCT06214260)
- Testing
- Peripheral blood sample, Menstrual Blood sample
- Where
- Hong Kong
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Endometriosis, Ovarian Reserve
Association Between Laparoscopic Removal of Endometriomas and Anti-mullerian Hormone Levels
Laparoscopic excision of endometriotic cysts is the main stream surgical intervention for treatment of endometriosis. However there is evidence that intervention may effect ovarian reserve by destruction of healthy ovarian tissue…
- Trial name
- NCT02685644
- Testing
- Laparoscopic removal of cysts
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Ankara University
Uterine Fibroids, Endometriosis
AMH Levels Change During Treatment With GnRh Agonist
To evaluate the variation of AMH levels in women undergoing treatment with GnRHa, and to assess whether this variation correlates with changes in the antral and pre-antral follicle ultrasonographic count (AFC).
- Conditions
- Uterine Fibroids, Endometriosis, Endometriosis of Uterus, Pelvic Pain
- Trial name
- NCT02086279
- Testing
- GnRH analogue
- Where
- Italy
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Endometriosis (Diagnosis), Endometriosis
Combining Ultrasound and Biomarkers to Diagnose Superficial Endometriosis
Endometriosis is a benign gynecological disease characterized by uterine-like cells growing outside the uterus, leading to pain, infertility, and inflammation.
- Trial name
- SPGENDO (NCT05523284)
- Testing
- SonoPODography
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- McMaster University
Cervical Cancer, Ovarian Cancer
Clinical Database and Biobank of Patients With Gynecologic Neoplasms
The database and biobank establishment started in 1997 in our institute. However, the sample size was too small with respect to our clinical and fundamental scientific research's requirement.
- Conditions
- Cervical Cancer, Ovarian Cancer, Endometrial Cancer, Choriocarcinoma
- Trial name
- NCT01267851
- Where
- China
- Volunteers
- 1,600,000 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Endometriosis, Endometrial Cancer
Serum Trace Element Levels in Some Gynecological Diseases
The aim of this clinical study is to measure the levels of various trace elements in the blood serum of women with various gynecological diseases and to compare them with healthy controls.
- Conditions
- Endometriosis, Endometrial Cancer, Over Cancer, Healthy Control
- Trial name
- NCT07210918
- Testing
- Blood Product
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Endometriosis
Evaluation of New Biomarkers in Stage 3 and 4 Endometriosis
The diagnostic value of Annexin V, sVCAM-1, sICAM-1, vascular endothelial growth factor and Proinflammatory cytokines (TNF-a and interleukin-6) in ovarian endometriosis and deep infiltrating endometriosis, their levels in…
- Trial name
- NCT05312528
- Testing
- endometriosis surgery, other benign condition surgeries
- Where
- Turkey (Türkiye)
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Bagcilar Training and Research Hospital
Polycystic Ovarian Syndrome, Pelvic Endometriosis
Prevalence of HbA1C in Women With PCOS
Women with PCOS have been observed to be potential diabetics.Recently,American Diabetes Association has suggested screening of women with PCOS for HbA1C.
- Conditions
- Polycystic Ovarian Syndrome, Pelvic Endometriosis, Insulin Resistance, Non-insulin Dependent Diabetes Mellitus
- Trial name
- WHI (NCT01838122)
- Where
- India
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Southern Cross Fertility Centre
Ovarian Endometrioma
Impact on Ovarian Reserve of Diode Laser vs Bipolar Coagulation of Endometriomas
Endometriosis is a benign chronic gynaecological disease that affects 10% of women of reproductive age and takes 40% of them to assisted reproduction techniques.
- Trial name
- NCT02350452
- Testing
- Diode laser coagulation, Bipolar coagulation
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Ovarian Reserve, Endometrioma
Endometrioma Per se Versus Treatment Related Reduction in Ovarian Reserve (ERROR-2 Trial)
The present multi-center study aimed to evaluate whether endometrioma-associated decline in ovarian reserve is progressive in the absence of an intervention and is greater in magnitude than the natural decline over time.
- Trial name
- ERROR2 (NCT03620838)
- Testing
- oral contraceptive pill, oral progesterone
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Uludag University
Infertility, Polycystic Ovary Syndrome
A New Algorithm to Predict Ovarian Age
To collect data of clinical, biochemical and 3D-ultrasonographic parameters of a population of fertile women aged 18-55 in order to design a new algorithm able to predict ovarian age and to evaluate the reliability of a…
- Conditions
- Infertility, Polycystic Ovary Syndrome, Premature Ovarian Failure (POF), Ovarian Cysts
- Trial name
- OvAge (NCT02086318)
- Testing
- OvAge assessment
- Where
- Italy
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Endometriosis, Polycystic Ovary Syndrome
Determination of the Incidence of Endometriosis and or Adenomyosis in Patients Diagnosed With Polycystic Ovary Syndrome, or the Incidence of Polycystic Ovary Syndrome in Patients Diagnosed With Endometriosis and or Adenomyosis
The study was designed as a multicenter, prospective cross-sectional cohort study. The research population will consist of patients under the age of 40, diagnosed with endometriosis and/or adenomyosis and polycystic ovary…
- Conditions
- Endometriosis, Polycystic Ovary Syndrome, Adenomyosis
- Trial name
- NCT04916171
- Testing
- incidence
- Where
- Turkey (Türkiye)
- Volunteers
- 2,450 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Endometriosis, Endometriosis Ovary
The Role of Galectins in the Non-invasive Diagnosis of Endometriosis
Endometriosis is one of the most common infertility-related gynecologic disorder that affect approximately 10-15% of women in reproductive age. The main symptoms are chronic pelvic pain, infertility, dysmenorrhea and dyspareunia.
- Conditions
- Endometriosis, Endometriosis Ovary, Endometriosis Rectovaginal Septum
- Trial name
- NCT04401592
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Ovarian Endometrioma
The Association Between Ovarian Endometrioma and Lower Urinary Tract Symptoms
To assess the relationship between ovarian endometrioma and lower urinary tract symptoms, sexual function and gastrointestinal symptoms.
- Trial name
- NCT02623244
- Testing
- Laparoscopic oophorocystectomy or oophorectomy
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Gynecologic Disease, Gynecologic Cancer
Evaluation of Salivary RNA in Subjects Scheduled for Surgery for a Gynecologic Pathology
GynRAN is an international, multicentre, transversal, diagnostic and non-interventional study carried out in gynecology-obstetrics/gynecological oncology departments that aims to identify a diagnostic signature for gynecological…
- Conditions
- Gynecologic Disease, Gynecologic Cancer, Endometriosis, Ovarian Cancer
- Trial name
- GynRNA (NCT06392997)
- Testing
- Saliva sample
- Where
- 13 sites in France
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- ZIWIG
Ovarian Reserve
Effects of Dienogest and Dienogest Plus Estradiol Valerate in Ovarian Endometrioma
Progesterone resistance in endometriosis is a known fact. The progestin derivatives used in endometriosis cause decidualization and atrophy of ectopic foci.
- Trial name
- NCT03789123
- Testing
- Estradiol valerate/dienogest
- Where
- Turkey (Türkiye)
- Volunteers
- 710 people, healthy volunteers welcome
- Sponsor
- Bagcilar Training and Research Hospital
Endometrioma
Surgicel Reduces Ovarian Endometriomas Recurrence
Two hundred women aged from 20 to 35 years undergoing conservative laparoscopic treatment of ovarian endometriomas (either by drainage or cyst wall excision) were included.
- Trial name
- NCT02947724
- Testing
- SURGICEL®
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cairo University
Endometriosis
The Impact of Surgical Treatment of Endometriomas on Ovarian Reserve
The aim of this study is to assess which of two commonly used surgical procedures in the treatment of ovarian cysts called endometriomas (cutting out of the cyst - "cystectomy", or draining it and cauterising it's inner lining …
- Trial name
- NCT01425333
- Testing
- Surgery for ovarian endometrioma
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Saad Amer